척추마취시 Midazolam 과 Diazepam 의 진정작용에 대한 비교

김미운,김성태,김혜경 대한마취과학회 1991 Korean Journal of Anesthesiology Vol.24 No.3

Midazolam, a water soluble benzodiazepine, was compared with diazepam as a sedation for spinal anesthesia. Forthy healthy patients were allocated at random to receive midazolam 0.1mg/kg or diazepam 0.2mg/kg at 15 min after tetracaine inction for spinal anesthesia and increments of half of the initial dose every 2 min to induce sleep. Mean dose of midazolam 8.5 mg and diazepam 17.1 mg were injected for sedation throughout surgery. There was no difference concerning sedation level during surgery and speed of recovery. With the same degree of sedation, midazolam produced a higher frequency of anterograde amnesia(70% vs. 30%). Uenous tolerance was better for midazolam. Neither drug caused obstruction of airway nor significant cardiovascular change. Higher degree of amnesia and venous tolerance with midazolam may be advantages of sedation for spinal anesthesia.

New method of assessing the relationship between buccal bone thickness and gingival thickness

Kim, Yun-Jeong,Park, Ji-Man,Kim, Sungtae,Koo, Ki-Tae,Seol, Yang-Jo,Lee, Yong-Moo,Rhyu, In-Chul,Ku, Young Korean Academy of Periodontology 2016 Journal of Periodontal & Implant Science Vol.46 No.6

Purpose: The aim of this study was to determine the relationship between buccal bone thickness and gingival thickness by means of a noninvasive and relatively accurate digital registration method. Methods: In 20 periodontally healthy subjects, cone-beam computed tomographic images and intraoral scanned files were obtained. Measurements of buccal bone thickness and gingival thickness at the central incisors, lateral incisors, and canines were performed at points 0-5 mm from the alveolar crest on the superimposed images. The Friedman test was used to compare buccal bone and gingival thickness for each depth between the 3 tooth types. Spearman's correlation coefficient was calculated to assess the correlation between buccal bone thickness and gingival thickness. Results: Of the central incisors, 77% of all sites had a buccal thickness of 0.5-1.0 mm, and 23% had a thickness of 1.0-1.5 mm. Of the lateral incisors, 71% of sites demonstrated a buccal bone thickness <1.0 mm, as did 63% of the canine sites. For gingival thickness, the proportion of sites <1.0 mm was 88%, 82%, and 91% for the central incisors, lateral incisors, and canines, respectively. Significant differences were observed in gingival thickness at the alveolar crest level (G0) between the central incisors and canines (P=0.032) and between the central incisors and lateral incisors (P=0.013). At 1 mm inferior to the alveolar crest, a difference was found between the central incisors and canines (P=0.025). The lateral incisors and canines showed a significant difference for buccal bone thickness 5 mm under the alveolar crest (P=0.025). Conclusions: The gingiva and buccal bone of the anterior maxillary teeth were found to be relatively thin (<1 mm) overall. A tendency was found for gingival thickness to increase and bone thickness to decrease toward the root apex. Differences were found between teeth at some positions, although the correlation between buccal bone thickness and soft tissue thickness was generally not significant.

An Experimental Exclusion of Mud Shrimps to Enhance Clam Production on the Jugyo Tidal Flat, West Sea, South Korea

Sungtae Kim,Sukhyun Nam,Cheol Yu,So-Hyuk Woo,Chae-Lin Lee,Yoon-Hee Jung,Jae-Sang Hong 한국수산과학회 양식분과 2016 한국수산과학회 양식분과 학술대회 Vol.2015 No.05

Advanced Energy Detector with Correlated Multiple Antennas

( Sungtae Kim ),( Sungmook Lim ) 한국인터넷정보학회 2021 KSII Transactions on Internet and Information Syst Vol.15 No.12

In cognitive radio networks where unlicensed secondary users opportunistically access to licensed spectrum unused by licensed primary users, spectrum sensing is one of the key issues in order to effectively use the frequency resource. For enhancing the sensing performance in energy detection-based spectrum sensing, spatial diversity based on multiple antennas is utilized. However, the sensing performance can be degraded when antennas are spatially correlated, resulting in inducing the harmful interference to primary users. To overcome this problem, in this paper, an advanced energy detector is proposed. In the proposed sensing method, a weight matrix based on the eigenvalues of the spatial channels without any prior information on the primary signals is defined and utilized. In numerical simulations, it is shown that the proposed detector outperforms the conventional detector with regard to false-alarm and detection probabilities when antenna are spatially correlated.

Pluripotency of male germline stem cells

Kim, Sungtae,Belmonte, Juan Carlos Izpisua Springer-Verlag 2011 Molecules and cells Vol.32 No.2

Periodontal pathogens and the association between periodontitis and rheumatoid arthritis in Korean adults

Kim, Jin-Hee,Choi, In Ah,Lee, Joo Youn,Kim, Kyoung-Hwa,Kim, Sungtae,Koo, Ki-Tae,Kim, Tae-Il,Seol, Yang-Jo,Ku, Young,Rhyu, In-Chul,Song, Yeong Wook,Lee, Yong-Moo Korean Academy of Periodontology 2018 Journal of Periodontal & Implant Science Vol.48 No.6

Purpose: Periodontitis and rheumatoid arthritis (RA) share a similar inflammatory pathogenesis. Porphyromonas gingivalis (Pg) can induce anticyclic-citrullinated peptide autoantibodies (anti-CCP antibodies), a key factor in the development of RA. This study aimed at evaluating the relationships between the 2 diseases and identifying the clinical implications thereof, with a focus on periodontal pathogens in Korean adults. Methods: A total of 260 RA patients and 86 age- and sex-matched control patients without arthritis were enrolled in this prospective cross-sectional study. Periodontal indices and the prevalence and amount of periodontal pathogens were compared between the groups. Correlations between periodontal and RA indices were examined, as were correlations between 9 periodontal pathogens and RA indices. Results: The RA group had significantly higher values than the control group for all investigated periodontal indices (P<0.05) except the number of teeth. The gingival index (GI) was correlated with the disease activity score 28 (DAS28) (r=0.125, P=0.049), RA disease duration (r=0.253, P<0.001), erythrocyte sedimentation rate (ESR) (r=0.162, P=0.010), and anti-CCP antibody titer (r=0.205, P=0.004). Probing pocket depth (PPD) was correlated with ESR (r=0.139, P=0.027) and anti-Pg antibody titer (r=0.203, P=0.001). Bleeding on probing (BOP) was correlated with DAS28 (r=0.137, P=0.030), RA disease duration (r=0.202, P=0.001), ESR (r=0.136, P=0.030), anti-Pg antibody titer (r=0.177, P=0.005), and anti-CCP antibody titer (r=0.188, P=0.007). Clinical attachment level (CAL) and periodontitis severity were correlated with anti-Pg antibody titer (the former r=0.201, P=0.002; the latter r=0.175, P=0.006). The quantity of Pg was positively correlated with the serum anti-Pg antibody titer (r=0.148, P=0.020). Conclusions: The GI, BOP, and PPD showed positive relationships with several RA indices. The anti-Pg antibody titer had positive relationships with PPD, BOP, CAL, and periodontitis severity. Thus, increasing values of periodontal indices could be used as a risk indicator of disease development in RA patients, and an increasing anti-Pg antibody titer could be considered as a warning sign in RA patients suffering with periodontitis.

Design and Assessment of Phase-Shifting Algorithms in Optical Interferometer

Sungtae Kim,Jurim Jeon,Yangjin Kim,Naohiko Sugita,Mamoru Mitsuishi 한국정밀공학회 2023 International Journal of Precision Engineering and Vol.10 No.2

Silicon wafers and transparent glass plates are major components in the semiconductor industry. In semiconductor devices, the surface shape and optical thickness of the wafers and glass plates are the key parameters for the optimal performance of the devices. Phase-shifting interferometry has been widely used to achieve precision measurements of these parameters. The phase-shifting algorithm significantly affects the interferometric measurement results with phase-shifting interferometry. In this review, we introduce the design and assessment of phase-shifting algorithms in the Fizeau interferometer. Section 2 categorized the phase-shifting algorithms designed by several methods in terms of their error compensation ability. Then, the optical setup of the Fizeau interferometer used for surface and thickness measurement is explained in Sect. 3. In addition, Sect. 4 explained the principle of phase extraction using phase-shifting interferometry and discussed its error sources. Moreover, design methods for the phase-shifting algorithm to eliminate error sources are introduced in Sect. 5. Finally, the error compensation abilities of designed algorithms are estimated by several methods in Sect. 6.

<i>Sophora flavescens</i> Aiton Decreases MPP ⁺ -Induced Mitochondrial Dysfunction in SH-SY5Y Cells

Kim, Hee-Young,Jeon, Hyongjun,Kim, Hyungwoo,Koo, Sungtae,Kim, Seungtae Frontiers Media S.A. 2018 FRONTIERS IN AGING NEUROSCIENCE Vol.10 No.-

<P><I>Sophora flavescens</I> Aiton (SF) has been used to treat various diseases including fever and inflammation in China, South Korea and Japan. Several recent reports have shown that SF has anti-inflammatory and anti-apoptotic effects, indicating that it is a promising candidate for treatment of Parkinson’s disease (PD). We evaluated the protective effect of SF against neurotoxin 1-methyl-4-phenylpyridinium ion (MPP<SUP>+</SUP>)-induced mitochondrial dysfunction in SH-SY5Y human neuroblastoma cells, an <I>in vitro</I> PD model. SH-SY5Y cells were incubated with SF for 24 h, after which they were treated with MPP<SUP>+</SUP>. MPP<SUP>+</SUP>-induced cytotoxicity and apoptosis were confirmed by 3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyl tetrazolium bromide assay and terminal deoxynucleotidyl transferase-mediated biotinylated UTP nick end labeling assay. MitoSOX red mitochondrial superoxide indicator, tetramethylrhodamine methyl ester perchlorate and Parkin, PTEN-induced putative kinase 1 (PINK1), and DJ-1 immunofluorescent staining were conducted to confirm the mitochondrial function. In addition, western blot was performed to evaluate apoptosis factors (Bcl-2, Bax, caspase-3 and cytochrome c) and mitochondrial function-related factors (Parkin, PINK1 and DJ-1). SF suppressed MPP<SUP>+</SUP>-induced cytotoxicity, apoptosis and collapse of mitochondrial membrane potential by inhibiting the increase of reactive oxidative species (ROS) and DNA fragmentation, and controlling Bcl-2, Bax, caspase-3 and cytochrome <I>c</I> expression. Moreover, it attenuated Parkin, PINK1 and DJ-1 expression from MPP<SUP>+</SUP>-induced decrease. SF effectively suppressed MPP<SUP>+</SUP>-induced cytotoxicity, apoptosis and mitochondrial dysfunction by regulating generation of ROS, disruption of mitochondrial membrane potential, mitochondria-dependent apoptosis and loss or mutation of mitochondria-related PD markers including Parkin, PINK1 and DJ-1.</P>

Acupuncture alters pro-inflammatory cytokines in the plasma of maternally separated rat pups

Kim, Dongsoo,Bae, Chang-Hwan,Jun, Ye Lee,Jeon, Hyongjun,Koo, Sungtae,Kim, Seungtae Springer-Verlag 2017 CHINESE JOURNAL OF INTEGRATIVE MEDICINE Vol.23 No.12

<P>Acupuncture stimulation at HT 7 can alleviate the behavioral impairment and changes of the cytokines by MS, indicating that acupuncture can help to relieve MS-induced depression.</P>

Periodontal biotype modification using a volume-stable collagen matrix and autogenous subepithelial connective tissue graft for the treatment of gingival recession: a case series

Kim, Hyun Ju,Chang, Hyeyoon,Kim, Sungtae,Seol, Yang-Jo,Kim, Hyeong-Il Korean Academy of Periodontology 2018 Journal of Periodontal & Implant Science Vol.48 No.6

Purpose: The purpose of this study was to propose a technique for periodontal biotype modification through thickening of the entire facial aspect using a volume-stable collagen matrix and autogenous subepithelial connective tissue graft (CTG) for the treatment of gingival recession. Methods: Four systemically healthy patients showing Miller class I or class II gingival recession in the mandibular incisor area were included in this study. Full-mouth scaling and root planing procedures were performed at least 4 weeks prior to periodontal plastic surgery. A split-thickness flap with a horizontal intrasulcular incision and 2 vertical incisions was used in cases 1-3, and the modified tunnel technique was used in case 4 for coronal advancement of the mucogingival complex. After the exposed root surfaces were debrided thoroughly, double-layered volume-stable collagen matrix was placed on the apical part of the recession and a subepithelial CTG harvested from the palatal area was placed on the coronal part. The amount of root coverage at 3 months postoperatively was evaluated in cases 1-3, and facio-lingual volumetric changes were analyzed in cases 1 and 2. Results: Healing was uneventful in all 4 cases and complete root coverage was shown in cases 1-3. In case 4, reduction of gingival recession was observed at 3 months after surgery. In cases 1 and 2, a comparison of stereolithographic files from the preoperative and postoperative time points demonstrated that the entire facio-lingual volume had increased. Conclusions: The surgical technique suggested herein, using a volume-stable collagen matrix and autogenous subepithelial CTG, may be an effective method for periodontal biotype modification through thickening of the entire facial aspect for the treatment of gingival recession.