Application of Antioxidant Transgenic Mice

Sun?Uk Kim,Hee-Young Yang,Sun-Hee Ahn,Suhee Kim,Dae?Yeul Yu,Dong?Seok Lee,Tae-Hoon Lee 한국실험동물학회 2014 한국실험동물학회 학술발표대회 논문집 Vol.2014 No.8

골격성 3급 부정교합자의 임상적 특성에 따른 심리상태

김선옥 ( Sun Ok Kim ),진미영 ( Mi Young Jin ),유병철 ( Byeng Chul Yu ) 한국치위생학회(구 한국치위생교육학회) 2015 한국치위생학회지 Vol.15 No.2

Objectives: The purpose of the study is to investigate the psychological state of the patients according to skeletal class Ⅲ malocclusion symptoms. Methods: The subjects were 200 skeletal class Ⅲ malocclusion patients. The questionnaire consisted of general characteristics, clinical manifestation, and T score of Korean version of self-rated Symptom Checklist-90-Revision modified by Jae-hwan Kim. The data were analyzed using SAS version 9.2 and t-test, ANOVA, and ANCOVA were used. Clinical manifestation included subjective recognition and radiological analysis. The subjective recognition of the patients consisted of self-satisfaction of the appearance, phonation, mastication, and temporomandibular joint pain. T score consisted of somatization, obsessive-compulsive, interpersonal sensitivity, depression, anxiety, hostility, phobic anxiety, paranoid ideation, and psychoticism. Results: The most serious factor in 9 scales was the severe TMJ pain by ANCOVA. Male patients had a higher T score in phobic anxiety, psyochoticism, somatization and depression than female patients. Those having low appearance satisfaction had the problem in interpersonal sensitivity. Obsessive-compulsive symptoms were conspicuous in phonation difficulty and temporomandibular pain. Conclusions: The patients with skeletal class Ⅲ malocclusion have more satisfaction with appearance, pronunciation, and phonation than those with skeletal class Ⅲ malocclusion and overjet. Proper dental treatment will improve the communication and quality of life.

혈관외피종 -1증례 보고-

강유미,지미경,양기화,강석진,김병기,김선무,정수일 대한병리학회 1990 Journal of Pathology and Translational Medicine Vol.25 No.5

Guar gum의 섭취 수준과 기간이 흰쥐의 영양소 흡수율에 미치는 영향

김상연,선영실,장유경 漢陽大學校 韓國生活科學硏究所 1993 韓國 生活 科學 硏究 Vol.- No.11

This study was performed to investigate apparent absorption of nutrients according to level and duration of guar gum intake. Eighteen male rats of Sparague-Dawley strain weighing 50g were blocked into three groups : FF, 5G, 10G(Fiber Free, 5% Guar gam, 10% Guar gum). Balance studies were conducted at 2nd week, 4th week and 8th week. Feed in-take body weight gains, apparent absorption of protein, fat, Ca and P were measured. The results obtained in this study were summarized as follows : (1) Feed intake was not significantly different among the groups during each balance studies. Weiht gain was decreased according to level of guar gum intake during each balance studies. (2) Protein apparent absorption of 5G were not significantly different with that of 10G at 2nd week and 4th week but at 8th week protein apparent absorption of 10G was singificantly lower than that of 5G According to duration of guar gum intake, protein apparent absorption of FF and 5G were not significantly different. Wherease protein apparent absorption of 10G was significantly decreased at 8th week. (3) Fat and Ca apparent absorption were not significantly different among groups at 2nd week. Fat apparent absorption of 10G was not significantly lower than that of 5G at 4th week and 8th week. According to duration of guar gum intake, fat and Ca apparent absorption of FF and 5G were not significant different. But fat and Ca apparent absorption of 10G was significantly decreased according to duration of fur gum intake. (4) Phosphorus apparent absorption were not significantly different among groups at 2, 4th week. But phosphorus apparent absorption of 10G were significantly higher than that of 5G at 8th week. According to duration of guar gum intake, phosphorus apparent absorption of FF and 10G were not influenced. But Phosphorus apparent absorption of 5G was significantly decreased according to duration of guar gum intake. From the results of this study, we could recommend 5% guar gum in diet of obese man and di abetics.

신규간호사와 프리셉터가 인지하는 프리셉터의 교수효율성 비교

김지양,김영선,김춘실,박현숙,신미영,윤연숙,조유숙,박미미,유문숙 한국간호과학회 간호행정학회 2009 간호행정학회지 Vol.15 No.2

Objective: The purpose of this study was to compare preceptors and new graduate nurses on their perception of preceptor teaching effectiveness. Methods: The participants were 90 new nurses and 90 preceptors who worked in A medical center. The data were collected from July 1 to September 30, 2008. A cross-sectional descriptive survey was done using a structured questionnaire. Results: New nurses' perception (4.07±.44) of the preceptor teaching effectiveness was significantly higher than perception of the preceptors (3.57±.37). Fifty five percent of new graduate nurses reported a lack of coherence in the preceptor's practice guidelines. For 5 causal factors classified on the teaching effectiveness, the factor of 'Professional knowledge and ability' showed the highest score, but 'Interpersonal and communication skill' got lowest score for both group. Preceptors responded that they did not have enough time to teach well because of their heavy workloads. Conclusions: These results suggest that the preceptors need appropriate compensation and education opportunities, and new graduate nurses need consistent education by the teaching professionals. Therefore, it is important to give preceptors full charge of the preceptorship. Also, it will be necessary to develop education programs to enhance interpersonal and communication skill for preceptors and new nurses.

노년기 여성의 생활만족도 및 외모만족도에 따른 의복만족도와 의복디자인 선호도에 대한 연구

김진구,서미아,이유경,이선희 服飾文化學會 1996 服飾文化硏究 Vol.4 No.1

The elderly population of Korea has been significantly increasing due to advances in public health, medical care, and quality of life. Social and economic influence of the elderly population has been also increasing. As elderly people become more interested in their appearance and clothing than before, clothing plays an important role in the elderly women's everyday life. The objectives of the research are to explore the life satisfaction, appearance satisfaction clothing satisfaction, and clothing design preferance of 416 women aged 55 years and older who were residents of Seoul. Data were gathered through survey using a self-administered questionnaire from November, 1994 to January, 1995 in 8 senior schools and 3 senior centers which were scattered in Seoul. Descriptive statistics, t-test, and factor analysis were used in analysing the data. The results of this study indicate that life satisfaction have a positive relationship with clothing satisfaction. The respondents were divided into two groups by life satisfaction. The higher life satisfaction group prefered skirts and formal wear to the lower. But, two groups did not show any significant differences in terms of the color preference, motif preference, and fabric preference. The result of factor analysis divided appearance satisfaction into body satisfaction and face satisfaction. Body satisfaction had a positive relationship with clothing satisfaction. And the group of lower physical satisfaction showed lower satisfaction in apparel fitness. Also the face satisfaction had a positive relationship with clothing satisfaction. The group of higher physical satisfaction prefered skirts and formal wear compared to that of lower physical satisfaction. The color preference and motif preference between two group showed no significant difference. And the group of higher physical satisfaction prefered fabric that enhances the clothing style. Also, the group of higher face satisfaction prefered fabric that enhances the clothing style. However, there was no significant difference in the color preference and motif preference between two groups. The findings of this study may contribute to knowledge about clothing satisfaction and preference of elderly women in Seoul since there have been few studies, and be useful to apparel manufacturers as well as clothing researchers. Also, research subjects of this study could be extended to aged men and various regions.

대학생의 취업스트레스와 자아존중감, 자아효능감, 외모관리행동의 관계

김보라,김유진,김지희,노혜진,오승희,홍지혜,황윤희,박선아 水原大學校 2016 論文集 Vol.30 No.-

Purpose: Many university students are under a lot of job-seeking stress because the employment rate is low. This study sought to determine the relationship between job-seeking stress, self esteem, self efficacy and appearance management behavior amongst university students focusing on nursing. Methods: This descriptive correlational study evaluated the relationships between job-seeking stress, self esteem, self efficacy and appearance management behavior of 340 university students was conducted between September 1 and October 5, 2015. Results: The correlational analysis between job-seeking stress, self esteem, self efficacy and appearance management behavior revealed a negative correlation between job-seeking stress, self esteem and self efficacy and a positive correlation between job-seeking stress and appearance management behavior. In addition, age also correlated with self esteem, self efficacy and appearance management behavior. Conclusion: Stress correlated with self esteem and self efficacy and appearance management behavior. Therefore job-seeking stress may be reduced through not only self esteem and self efficacy enhancement programs but also management according to age.

항산화 및 미생물의 성장에 대한 해양성 심층수의 영향

김유정,정일선,최영주 신라대학교 자연과학연구소 2006 自然科學論文集 Vol.15 No.-

해양심층수의 첨가에 따른 항산화력과 된장에서 분리한 Bacillus, 석유분해균인 Sphingomonas 및 효모의 증식을 측정하였다. Bacillus와 Sphingomonas 경우는 KDMW와 다나수의 첨가에 의해서 균주의 생육이 증가되었을 뿐만 아니라 정지기 및 사멸기에 도달하는 시간도 연장되는 것으로 보아 심층수에 있는 미네랄이 이러한 생리활성을 나타내는 것으로 추정된다. 효모의 경우는 심층수의 첨가에 의하여 대조구와 별다른 차이를 보이지 않고 있다. 항산화력의 경은 KDMW를 50%까지 첨가 했을 경우는 25% 항산회력을 나타냈지만 60% 이상 첨가하면 오히려 항산회력이 현저히 감소하였다. 다나수의 경우는 40 - 100% 범위내에서 약 20%의 유사한 활성을 나타냈다. Korean deep mineral water (KDMW) has a similar mineral composition with deep sea water KDMW has demonstrated its usefulness and attracted in the medical fields. KDMW intake improves antioxidant activity and the growth of fermentation related strains. The antioxidant activity was increased up to 23% by the addition of 40% KDMW. The growth rate of Bacillus sp. on medium containing KDMW(40%) was faster than that of the strain on the medium without it. These results suggest that the minerals in KDMW play an important role for activation of immune system and the microbial growth. In addition to, it is considered that the study on the effects of abundant minerals of deep mineral water in the fermentation will by continued.

PCR 기법을 이용한 한국재래산양 β-casein 유전자의 특성

김지애,류승희,유성란,이준헌,서길웅,김선균,상병찬 충남대학교 농업과학연구소 2002 농업과학연구 Vol.29 No.2

본 연구는 한국 재래 산양 112두와 유산양인 Saanen종 7두의 혈액으로부터 genomic DNA를 추출하고, PCR-RFLP 방법에 의해 β-casein 유전자의 특성을 분석하여 한국재래산양의 효율적인 유전자원의 보전 및 개량을 위한 기초 자료로 제공하고자 실시하였다. 한국재래산양의 genomic DNA로부터 PCR기법을 이용하여 β-casein의 유전자좌를 증폭한 결과 각각 481bp 크기의 단편이 양호하게 증폭되었음을 확인하였다. β-casein 유전자좌의 증폭산물에 대한 Bal Ⅰ의 제한효소를 처리한 결과, β-casein AB형은 481bp, 284bp 및 197bp의 단편을, 그리고 BB형은 284BP와 197BP의 단편을 한국재래산양과 유산양인 Saanen 종에서 확인 할 수 있었다, 유전자형 빈도에 있어서는 한국재래산양에서 β-casein AB 및 BB의 빈도는 각각 6.25 및 93.75%이었고, 유산양인 Saanen 종은 각각 57.14 및 42.86%이었다. 유전자빈도에 있어서는 한국재래산양의 β-casein A 및 B의 빈도가 각각 0.031 및 0.969이었고, Saanen 종에서는 각각 0.286 및 0.714의 빈도를 보였다 한국재래산양의 β-casein 유전자의 염기서열과 이미 보고되어 있는 goat의 염기서열(GeneBank accession Number M90556)간에는 총 11개의 염기서열에 차이를 나타내어 97.71%의 상동성을 보였다, 따라서 한국재래산양의 β-casein 유전자의 다형성과 염기서열 분석에 의한 분자유전학적 특성의 규명은 한국재래산양의 유전자원의 보전 및 개량을 위한 기초 및 응용 자료로 이용될 수 있을 것으로 생각된다. This study was performed to provide the basic data for preservation and improvement of genetic resources according to finding genetic construction obtained from analysis of genetic characteristics of β-casein gene in Korean Native goat and Saanen using the PCR-RFLP. This study confirmed the amplified products of 481bp fragments obtained from the amplification of β-casein loci by PCR. The β-casein AB genotype showed 481, 284 and 197bp, and β-casein BB genotype showed 284 and 197bp fragments in Korean Native goat and Saanen. The frequencies of β-casein genotype in Korean Native goat were 6.25 and 93.75% for AA and AB and the frequencies of β-casein genotype in Saanen were 57.14 and 42.86% for AA and AB types. The frequencies of β-casein A and B alleles were 0.031 and 0.969 in Korean Native goat and the frequencies of β-casein A and B alleles are 0.286 and 0.714 in Saanen, respectively. The nucleotide sequence of β-casein gene of Korean Native goat was 97.71% higher homology with 11 nucleotide sequences difference of that of goat reported in GeneBank (M90556). Therefore, this study of molecular genetic characteristics by the analysis of genetic polymorphism and sequencing for β-casein gene should be used as basic and applying data for preservation and improvement of genetic resources in Korean Native goat breeding.

관상동맥 질환에서 SDF-1α의 농도

김보영,박용규,박형서,노상필,정승현,이유선,이정우,이재환,최시완,정진옥,성인환 충남대학교 의과대학 의학연구소 2003 충남의대잡지 Vol.30 No.1

Atherosclerosis is now viewed as an inflammatory disease of the vascular system. Expression of several chemokines, including monocyte chemoattractant protein(MCP)-1, MCP-4, RANTES(regulated on activation normal T-cell expressed and secreted), and interleukin-8(IL-8) are increased in human atherosclerotic plaques compared with normal vessels. They are involved in the pathogenesis of atherosclerosis and plaque rupture by activating and directing leukocytes into the atherosclerotic lesions. However, some are involved in homeostatic functions such as normal leukocyte traffic and growth regulation. SDF-la is a multi-functional cytokine that is involved in myelogenesis, hematopoiesis, angiogenesis and injured gastric mucosal regeneration in the gastric ulcer patient. SDF-la is recently shown to be highly expressed in atherosclerotic plaques and a potent platelet agonist. At least in high concentrations, SDF-la may mediate antiinflammatory and matrix stabilizing effects in unstable angina. Many studies are going on to know the function of SDF-la in coronary artery diseases. I investigated the difference of the plasma level of SDF-la between control group and coronary artery disease group. Total 75 subjects were enrolled. The diagnosis of coronary artery disease was confirmed in all patients by coronary angiography. Control subjects in this study were confirmed normal by coronary angiography. Clinical profile and risk factors were also reviewed. Control subjects in this study were 27 (M=10, F=17). Plasma for the study was collected before the angiography and centrifuged. SDF-la analysis was performed by ELISA. Plasma level of SDF-la is significantly increased in patients with stable angina(n=20) and unstable angina group(n=28) compared with healthy control group(n=27). the risk factors do not influence the plasma level of SDF-la in coronary artery diseases. In this study, plasma level of SDF-la is increased in patients with stable angina and unstable angina groups compared with healthy control group(P<0.05). the risk factors do not influence the plasma level of SDF-la in coronary artery diseases.