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      • 북한문학과 근대성

        김형수 국립7개대학공동논문집간행위원회 2004 人文學論叢 Vol.4 No.-

        The discussion North Korean literature has to be begun from researching its modernity. The realization of the modernity for the North Korean socialism is propeled by Kim Ilsungism, North Korean predominant ideology. Therefore, the study for Kim Ilsungism is the first work of the discussion of the North Korean literature. The Kim Ilsungism has based on Juche ideology. But, not like Juche ideology as a doctrine for a human being, the Kim Ilsungism has took its root in the doctrine for the head. This means that the Kim Ilsungism is a kind of identical logic which is concentrative itself with never accepting other thought. This identical logic is a product of making Kim Ilsung as national philosophical subject with desiring for establishment of solitary controlling system. With putting Juche ideology into Kim Ilsung himself, he makes his position to the top as the object which has absolute powered. This is the right reason why people has not been the subject of the history. The Kim Ilsungism emphasize that the modernity of North Korean socialism through the reconstruction of human being, society and nature has to be actualized by only its boos, Kim Ilsung. As this reason, I stand on my opinion that the discussion of the North Korean literature has to set its starting on researching Kim Ilsungism.

      • KCI등재후보
      • KCI등재

        인천지역 TDI 노출 작업자에서 직업성천식 유병율

        김형렬,김철우,홍윤철,전형준,김치년,김현수,이지나,신주연,고동희,노재훈 大韓産業醫學會 2004 대한직업환경의학회지 Vol.16 No.2

        목적 : TDI는 직업성천식을 일으키는 대표적인 물질로 알려져 있다. 과거 TDI에 노출된 작업자들의 천식 발생률을 5~6%가량 보고하였고, 국내에서도 2-20%에 이르는 유병율을 보고한바 있다. 작업환경이 많이 개선되고, 노출량이 감소된 최근에도 TDI에 의한 직업성천식에 대한 보고가 많이 이루어지고 있어, 이에 대한 적극적인 조사와 진단과정을 통해 유병율을 구하고 질병발생의 변화양상을 파악해 보고자 하였다. 방법 : 인천지역에서 특수건강진단을 수행하는 2개 기관의 TDI 노출 근로자 400여명 중, 사업장의 규모가 50인 이상이며 사업주가 연구진행을 허락한 사업장에서 근무하는 근로자 중 직접적으로 TDI에 노출되는 작업에 종사하는 근로자 170명을 연구대상으로 하였다. 이들에 대해 설문지와 산업의학의사의 면담을 통한 작업관련성 평가를 근거로 정밀대상자를 선정하고 이들에 대해 메타콜린 유발시험, TDI 유발시험 등을 수행하여 직업성천식을 확인하였다. 결과 : 설문조사 결과 11명이 직업과 관련하여 천식증상을 보이는 것으로 나타났고(6.9%), 이중 7명에서 메타콜린 유발검사 양성소견을 보였다. TDI에 의한 특이유발시험 결과 1명에서 양성반응이 나타나, 이 집단에서 TDI에 의한 직업성천식의 유병율은 0.58%였다. 결론 : 과거 국내연구에서 TDI에 의한 직업성천식의 유병율이 2~20%에 이르렀던 데 비해, 본 연구에서는 0.58%로 나타났다. 이는 국외 논문에서도 나타나는 경향으로 작업장 노출량 감소로 점차 발생률이 감소하는 양상을 보이고 있다. 그러나 이미 증상이 나타난 근로자들이 부서를 옮기거나, 직장을 그만둠으로 인해 그 유병율이 과소평가되었을 가능성도 있다고 판단된다. Objecdives: This study was carried out to estimate the prevalence of isocyanate-induced occupational asthma in toluene diisocyanate (TDI) exposed workers. Methods: We examined 170 workers who had been directly exposed to TDI through a medical questionnaire, physical examination, and pulmonary function test. Based on screening examination, workers with suspected occupational asthma were selected for further evaluation such as methacholine and TDI challenge tests. Results: Eleven (6.9%) among 170 workers complained of symptoms of occupational asthma. and 7 among these 11 symptomatic workers showed positive responses to the methacholine challenge test (4.1 %). One spray painter was confirmed as having the TDI induced occupational asthma following a positive response to TDI challenge test. Conclusions: The prevalence of TDI-induced asthma was at 0.58% was lower than that for former studies (2-20%). Improved workplace environment, lower level of TDI exposure compared to the past, and the healthy workers effect may have contributed to this low rate of asthma prevalence in workers with TDI exposure.

      • 간 세포암에서 VEGF, TGF-β1, b-FGF 발현의 의의

        김성용,남충현,주종우,채만규,백무준,이문수,김형철,안현철,김홍수,김창진,김창호 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.1

        Purpose: Angiogenesis is important for the proliferation and the metastasis of solid tumors. The growth of a solid tumor is widely recognized to depend on the process of neovascularrozation. Without angiogenesis, tumors cease to grow beyond even a few milimeters in diameter. It has been shown that tumor vascular density is an independent prognostic marker in several types of human tumors and is known to correlate with poor prognosis. To date, many angiogenic factors have been identified, such as transforming growth factor-α(TGF-α), transforming growth factor-β(TGF-β), fibroblast growth factor family(FGF), vascular endothelial growth factor(VEGF), platelet derived endothelial cell growth factor(PD-ECGF), tumor necrosis factor-α(TNF-α), and angiogenin. Hepatocellular carcinoma(HCC) is the second most common tumor in Korean males and is known as a typical hypervascular tumor with frequent portal vein invastion. The authors identified the expreesion of VEGF, TGF-β1, and b-FGF in HCC specimens and evaluated the relationship between these growth factors and the clinicopathologic characteristics of HCC. Method: We reviewed the medical records of 30 patients who were diagnosed as hepatocellular carinoma treated with hepatic resection between January 1994 and December 1998 in Soonchunhyang University Chunan Hospital. The selection of the cases was decided according to the condition of paraffin block fixation. The prognostic factors such as age, sex, tumor size, concentration of serum α-fetoprotein, presence of liver cirrhosis, presence of tumor emboli in portal vein, TMN stage, amount of transfusion during the operation, hepatitis B virus(HBV) infection, and Edmonson-Steiner(E-S) grade were investigated. Relationship between the prognostic factors and the immunopathologic expression of the TGF-β1, b-FGF, and VEGF was examined. Result: Thirty patients (24 males, 6 females) were included in the current study. The patient's mean age was 50.6 years and the age ranged from 36 to 65 years. The mean size of the tumor was found to be 5.2cm. All the patients were follewed up for 7 to 63 months. Child's classification A patients were 23(76.7%)cases, B patients were 7(23.3%)cases, and C was none. Immunohistochemical staining of HCC tumor mass in VEGF expression patients were 17(56.7%), b-FGF expression patients were 10(33.3%), and TGF-β1 expression patients were 10(33.3%). VEGF expression or more than one positive expression among the three factors correlated with tumor size and the stage of HCC but did not correlated with other clinicopathological characteristics. TGF-β1 and b-FGF did not correlate with any clinicopathological characteristics. Conclusion: The results suggest that the expression of VEGF or more than one positive expression among the three factors in HCC cells may be a significant prognostic factor of HCC.

      • KCI등재

        Underlying representations in glide formation in Korean: A reply to Cho (2000)

        Hyung-Soo Kim 한국음운론학회 2002 음성·음운·형태론 연구 Vol.8 No.1

        Kim, Hyung-Soo. 2002. Underlying representations in glide formation in Korean: A reply to Cho (2000). Studies in Phonetics, Phonology and Morphology 8.1. 65-83. One of the most recalcitrant problems in Korean phonology has been the explanation of the irregular continuative form wa<oa ""come[continuative]""(cf inf. o-ta) where, unlike verbs such as poa, pwa ""see[continuative]""(cf. inf. po-ta), glide formation occurs obligatorily without compensatory lengthening. In Kim (1999) it has been proposed that the exceptional behavior of the verb 0- can be most aptly explained by positing its underlying form as WΛ, whose stem vowel drops before a vowel-initial ending but contracts with the preceding W to become 0 before a consonant-initial suffix. Cho (2000), however, has criticized this analysis as being too opaque, employing a synchronically unmotivated underlying representation. This paper responds to her criticism by reviewing and revaluating all of the underlying representations posited in previous analyses while offering additional arguments for the abstract underlying form WΛ. (Jeonju University)

      • 장기간의 에어로빅스 운동이 골형성 및 각종 호르몬과의 상관관계

        김종인,김은희,김주혁,김수진,김도형,장성동 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.3

        Selected girl mid㎗e school of 14- and 15- years-old who got 35% body fat rate and are obese, and have them aerobics exercise for 20 weeks, the conclusion on the matter of change between Osteoporosis and Hormones showed. The contents of Calcium has significant difference(p<.05) between 9.38±0.34㎎/㎗ pre-exercise and 9.34±0.29㎎/㎗ post-exercise, and the contents of Glucose has significant difference (p<.05) between 78.0±5.38㎎/㎗ pre-exercise and 81.3±5.91㎎/㎗ post-exercise. parathyroid hormone (PTH) is shown as 11.2±3.06pg/㎖ at pre-exercise arid 13.8± 4.41pg/㎖ at post-exercise, hyperparathyroidism and osteoporosis (Osteocalcin) is shown as 6.04±3.56ng/㎖ at pre-exercise and 5.29±4.92ng/㎖ at post exercise, there is no significant difference. Deoxypyridinoline is shown as like 8.18±2.43nM/mMcre pre-exercise arid 9.97±2.76nM/mMcre post-exercise, Alkaline phosphatase (ALP), which has an effect on the born disease, is shown 229.7±61.66[U/㎖ pre-exercise and 224.3±8.27 [U/㎖ post-exercise, there is significant difference(p<.0l). There is significant difference (p<.05) between Growth Hormone and Parathyroid hormone(PTH) which is bone absorption hormone, the Osteocalcin which is the mark of born-formation, there is no significant difference among the index of born formation mark, lipid, and hormones.

      • KCI등재

        Universal Phonological Processes in eastern Bantu : a Theoretical analysis

        Kim,Hyung Soo 대한언어학회 1999 언어학 Vol.7 No.1

        Kim, Hyung-Soo. 1999. Universal Phonological Processes in eastern Bantu: a theoretical analysis. Linguistics 7-1, 199-225 In this paper the concept of universal phonological process in Foley's Theoretical Phonology is utilized to first introduce five phonological processes that commonly occur in eastern Bantu languages and then explain two important problems in morphophonemic alternation occurring in Luganda first singular present forms and Swahili adjectives. The five processes introduced are glide formation, syncope, glide strengthening, assibilation, and dissimilation. These processes are argued to be universal because 1) they occur not only in many Bantu languages but also in remotely related languages such as Korean and 2) their knowledge is required as a prerequisite to finding a coherent explanation of the two morphophonemic alternations. A brief comment on the ramifications of the analysis for the phonological theory in general is also included, especially the difficulties that a constraint-based approach may face in analyzing phonological probelms of this type. (Jeonju University)

      • KCI등재후보

        흰쥐 해마박편에서 veratrine과 고농도 포타슘자극시 칼슘이온이 gamma-aminobutyric acid 유리에 미치는 영향에 관한 연구 : A role of calcium

        강수만,김형룡,김관식,정동균 대한구강생물학회 1991 International Journal of Oral Biology Vol.15 No.2

        Present study was performed to clarify the effect of calcium on the release of gamma-aminobutyric acid (GABA) employing hippocampal slices. Hippocampal slices(300-400㎛ thick) were prepared by the method of Kim et al(1988) and pre-equilibrated in Krebs-bicarbonate medium(KBM, pH 7.4) for 1hr at 37℃. In case of veratrine-induced GABA release, pre-equilibrated slices were incubated in fresh KBM and then veratrine (25μM)-containing KBM for 10min period in the presence or absence of 2.5mM Ca^2+. In case of potassium-induced GABA relaese, pre-equilibrated slices were incubated in fresh KBM and then potassium(50mM)-containing KBM for 5min period in the presence or absence of 2.5mM Ca^2+. Basal and veratrine and potassium-induced release of GABA was determined from recovered medium by HPLC. The observed results were as follows: 1. The release of GABA induced by the 10min-exposure of 25μM veratrine and 5min-exposure of 50mM potassium in the presence of 2.5mM Ca^2+ was 228.9±11.2 nmol and 100.1±8.9nmol, respectively. When compared with released amounts of GABA during the corresponding spontaneous periods, these were 6.8 and 4.6-fold increase respectively. 2. The release of GABA induced by the 10min-exposure of 25μM veratrine and 5min-exposure of 50mM potassium in the absence of Ca^2+ was 381.4±30.2 nmol and 55.1±4.1 nmol, respectively. When compared with released amounts of GABA during the corresponding spontaneous periods, these were 11.3 and 2.4-fold increase respectively.

      • KCI등재

        Meinhof's Rule in Bantu Revisited : with special reference to Chibemba

        Kim, Hyung Soo 대한언어학회 1999 언어학 Vol.7 No.2

        Kim, Hyung-Soo. 1999. Meinhof's Rule in Bantu Revisited. Linguistics 7-2, 183-206. Well known to any Bantu phonologist is Meinhof's Rule, a dissimilation phenomenon observed between two nasal compounds in successive syllables. This paper analyzes application of this rule in Chibemba, a Bantu language spoken in Zambia. Chibemba has been previously classified by Meeussen(1963) and Meinhof(1932) as one of those Bantu languages in which the dissimilation rule occurs under a more limited condition. It is argued that such restriction is unnecessary in light of the data presented by Mann(1977). It is shown that the application of Meinhof's Rule in Chibemba occurs essentially under the same universal condition on dissimilation as in other Bantu languages, for example, Luganda. To place the analysis in proper context, I begin with discussion of Meinhof's Rule as a dissimilation; its interpretation, the mechanism of change, and the rule's condition and reflexes in Bantu languages. (Jeonju University)

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