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      • KCI등재

        Composition of Optimal Nutrient Solution for Single-stemmed Rose 'Red velvet' in a Closed Aeroponic System

        Kang Mu Jang,Lee Joo Hyun,Lee Yong-Beom The Korean Society for Bio-Environment Control 2005 생물환경조절학회지 Vol.14 No.3

        Experiments were carried out to develop an optimal nutrient solution for the single-stemmed rose (Rosa hybrida L.) 'Red velvet' in a closed aeroponic system. Plants were grown in 1/3, 1/2, 1, or 3/2 strength of the nutrient solution of National Horticultural Research Station in Japan (NHRS). Significantly less changes of pH and EC ($dS{\cdot}m^{-1}$) in the drainage were observed in 1/2 strength treatment as compared to other treatments. The $NO_3-N$, K, Ca, and Mg concentrations in the drainage solution of 1/2 strength treatment were maintained at optimal levels. These results indicated that the rose uptakes of both nutrients and water was more stable than those in other concentration. The concentration of macronutrients in nutrient solution were adjusted based on the ratio of nutrient:water (n/w) taken up by plants grown in the 1/2 strength solution. The composition of the new solution (classified the University of Seoul (UOS) solution) was as follow; $NO_3-N$ 8.8, $NH_4-N$ 0.67, P 2.0, K 4.8, Ca 4.0, Mg 2.0 $me{\cdot}L^{-1}$. To further evaluate new solution on crop growth, the rose 'Red Velvet' was grown again in l/2, 1, and 2 strength UOS solution to compare with 1.0 strength PBG (proefstion voor bloemisterij en glasgroenpe) solution. Overall the plant growth, including the stem length and number of five-leaflet leaves was higher in 1.0 strength of UOS solution than other treatments. Results presented in this study indicate that the nutrients in the UOS solution are well balanced for the single-stemmed rose in the closed aeroponic system.

      • KCI등재

        Composition of Optimal Nutrient Solution for Single-stemmed Rose 'Red velvet' in a Closed Aeroponic System

        Mu Jang Kang,Joo Hyun Lee,Yong-Beom Lee (사)한국생물환경조절학회 2005 시설원예‧식물공장 Vol.14 No.3

        Experiments were carried out to develop an optimal nutrient solution for the single-stemmed rose (Rosa hybrida L.) 'Red velvet' in a closed aeroponic system. Plants were grown in 1/3, 1/2, 1, or 3/2 strength of the nutrient solution of National Horticultural Research Station in Japan (NHRS). Significantly less changes of pH and EC (dSㆍm?¹) in the drainage were observed in 1/2 strength treatment as compared to other treatments. The NO₃-N, K, Ca, and Mg concentrations in the drainage solution of 1/2 strength treatment were maintained at optimal levels. These results indicated that the rose uptakes of both nutrients and water was more stable than those in other concentration. The concentration of macronutrients in nutrient solution were adjusted based on the ratio of nutrient water (n/w) taken up by plants grown in the 1/2 strength solution. The composition of the new solution (classified the University of Seoul (UOS) solution) was as follow; NO₃-N 8.8, NH₄-N 0.67, P 2.0, K 4.8, Ca 4.0, Mg 2.0 meㆍL?¹. To further evaluate new solution on crop growth, the rose 'Red Velvet' was grown again in 1/2, 1, and 2 strength UOS solution to compare with 1.0 strength PBG (proefstion voor bloemisterij en glasgroenpe) solution. Overall the plant growth, including the stem length and number of five-leaflet leaves was higher in 1.0 strength of UOS solution than other treatments. Results presented in this study indicate that the nutrients in the UOS solution are well balanced for the single-stemmed rose in the closed aeroponic system.

      • SCISCIESCOPUS

        Cks1 regulates human hepatocellular carcinoma cell progression through osteopontin expression

        Kang, Yu-Seon,Jeong, Eun-Jeong,Seok, Hyun-Jeong,Kim, Seon-Kyu,Hwang, Jin-Seong,Choi, Mu Lim,Jo, Dong-Gyu,Kim, Yuna,Choi, Jinhyeon,Lee, Yeo-Jin,Jung, Eunsun,Min, Jeong-Ki,Han, Tae-Su,Kim, Jang-Seong Elsevier 2019 Biochemical and biophysical research communication Vol.508 No.1

        <P><B>Abstract</B></P> <P>Precise cell cycle regulation is critical to prevent aberrant cell proliferation and cancer progression. Cks1 was reported to be an essential accessory factor for SCF<SUP>Skp2</SUP>, the ubiquitin ligase that targets p27<SUP>Kip1</SUP> for proteasomal degradation; these actions drive mammalian cell transition from G1 to S phase. In this study, we investigated the role played by Cks1 in the growth and progression of human hepatocellular carcinoma (HCC) cells. Silencing Cks1 expression abrogated osteopontin (OPN) expression in a p27<SUP>Kip1</SUP>-dependent manner in Huh7 HCC cells. OPN increased the proliferation, migration and invasion of Huh7 cells. Pharmacological inhibitor studies demonstrated that ERK1/2 signaling is responsible mainly for Cks1-mediated OPN expression. Cks1 appears to regulate ERK1/2 signaling through the expression of dual-specificity phosphatase 16 (DUSP16) because both Cks1 knockdown, which leads to DUSP16 upregulation, and DUSP16 overexpression decreased ERK1/2 phosphorylation and the resulting OPN expression. The same is true for the Cks1-mediated increases in p27<SUP>Kip1</SUP>, suggesting that Cks1 regulates OPN expression through activating ERK1/2 signaling either by suppressing DUSP16 expression or by a p27<SUP>Kip1</SUP>-dependent mechanism. Cks1 and OPN expression levels were significantly higher, but DUSP16 expression levels were significantly lower in HCC tissues than in normal liver tissues. Both Cks1 and OPN expression were negatively correlated with DUSP16 expression, whereas Cks1 expression was positively correlated with OPN expression. Moreover, combined panels for the expression levels of Cks1, DUSP16 and OPN showed significant prognostic power for the risk assessment of HCC patient overall survival. In conclusion, our data propose a novel function for Cks1 as a tumor promoter through the expression of the strongly oncogenic protein OPN in HCC.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Cks1 promotes OPN expression in human HCC cells. </LI> <LI> The Cks1-mediated upregulation of DUSP16 or p27<SUP>Kip1</SUP> decreased OPN expression. </LI> <LI> DUSP16- or p27<SUP>Kip1</SUP>-mediated ERK1/2 inactivation is responsible for OPN abrogation. </LI> <LI> Cks1, DUSP16 and OPN may be a useful prognostic biomarker panel for HCC patients. </LI> </UL> </P>

      • SCISCIESCOPUS

        Design issues in cross-sectional biomarkers studies: Urinary biomarkers of PAH exposure and oxidative stress

        Kang, Daehee,Lee, Kyoung-Ho,Lee, Kyoung-Mu,Kwon, Ho-Jang,Hong, Yun-Chul,Cho, Soo-Hun,Strickland, Paul T. Elsevier 2005 Mutation research Vol.592 No.1-2

        <P><B>Abstract</B></P><P>Cross-sectional biomarker studies can provide a snapshot of the frequency and characteristics of exposure/disease in a population at a particular point in time and, as a result, valuable insights for delineating the multi-step association between exposure and disease occurrence. Three major issues should be considered when designing biomarker studies: selection of appropriate biomarkers, the assay (laboratory validity), and the population validity of the selected biomarkers. Factors related to biomarker selection include biological relevance, specificity, sensitivity, biological half-life, stability, and so on. The assay attributes include limit of detection, reproducibility/reliability, inter-laboratory variation, specificity, time, and cost. Factors related to the population validity include the frequency or prevalence of markers, greater inter-individual variation than intra-individual variation, intra-class correlation coefficients (ICC), association with potential confounders, invasiveness of specimen collection, and subject selection.</P><P>Three studies are selected to demonstrate different features of cross-sectional biomarker studies: (1) characterizing the determinants of the biomarkers (study I: urinary PAH metabolites and environmental particulate exposure), (2) relationship of multiple biomarkers of exposure and effect (study II: relationship between urinary PAH metabolites and oxidative stress), and (3) evaluating gene–environmental interaction (study III: effect of genetic polymorphisms of <I>GSTM1</I> on the association of green tea consumption and urinary 1-OHPG levels in shipbuilding workers).</P>

      • Systematic Review for Exposure Assessment of Polycyclic Aromatic Hydrocarbons (PAHs)

        Jang Woo Park,Young Joo Lee,Ga Young Song,Yong-Mu Kim,Yun-Sook Kang 한국식품영양과학회 2021 한국식품영양과학회 학술대회발표집 Vol.2021 No.10

        Polycyclic aromatic hydrocarbons (PAHs) are compounds consisting of more than two aromatic rings. They are produced during the incomplete combustion of substances or cooking·processing under high temperature and pressure. We have identified the hazardous characteristics of the substance, and the various exposure media such as foods, environments, and commodities. The possible routes of exposure are intake, inhalation, and dermal absorption. In this study, we conducted the evaluation of 8 species of PAHs including BaP, Chry. BaA, BbFA, BkFA, DBahA, BghiP, and IP. For evaluation of the PAHs in food consumption, particularly regarding concentration changes at level of the pre- and post-cooking, we have investigated the national Total Diet Study (TDS), and the Korea National Health and Nutrition Examination Survey (KNHANES). The environments-and commodities-related monitoring data with validity of PAHs have been systematically reviewed from the recent scientific reports in Korea for estimating the exposure levels. This study can provide the basis for conducting an integrated risk assessment of PAHs.)

      • 釜山市 地下商街의 大氣汚染度에 관한 調査硏究

        鄭長均,李武康,洪性洙 慶星大學校 1990 論文集 Vol.11 No.2

        This study was performed to investigate air pollution of 2 underground shopping centers and 1 subway station in Busan, SO₂ CO, No₂ and THC were measured 4 times (a time each quarter) during 1987. The results were as follows. 1. The mean concentration of SO₂was 21.6 ppb at 3 sites and those were comparatively good air quality. The trends of concentration changes were same at 3 sites through seasons. 2. The mean concentration of CO was 3.86 ppm at 3 sites and there were no significant differences in levels among 3 sites. 3. The mean concentration of NO₂was 37.5ppb at 3 sites, all sites showed high concentration in summer season. 4. The mean concentration of THC was 8.4ppm at 3 sites, and showed higher pollution degree than the other pollutants. Methane of that was 3.55ppm, non methane was 4.88ppm, and the contribution of nonmethane was greater (about 3:2). 5. There were significant correlation between SO₂and CO(r=0.6738), NO₂and THC(4=0.7143). 6. To control of indoor air quality, comprehensive and systematic measures shouded be established.

      • Comparing esthetic smile perceptions among laypersons with and without orthodontic treatment experience and dentists

        Seong-Mu An,Sun-Young Choi,Young-Wook Chung,Tae-Ho Jang,Kyung-Hwa Kang 대한치과교정학회 2014 대한치과교정학회지 Vol.44 No.6

        Objective: The purpose of this study was to examine whether orthodontic treatment experience affects the individual’s perception of smile esthetics and to evaluate differences among orthodontically treated laypersons, non-treated laypersons, and dentists by using computerized image alterations. Methods: A photograph of a woman’s smile was digitally altered using a software image editing program. The alterations involved gingival margin height, crown width and length, incisal plane canting, and dental midline of the maxillary anterior teeth. Three groups of raters (orthodontically treated laypersons, non-treated laypersons, and dentists) evaluated the original and altered images using a visual analog scale. Results: The threshold for detecting changes in maxillary central incisor gingival margin height among laypersons was 1.5 mm; the threshold of dentists, who were more perceptive, was 1.0 mm. For maxillary lateral incisor crown width and height, the threshold of all three groups was 3.0 mm. Canting of the incisal plane was perceived when the canting was 3.0 mm among non-treated laypersons, 2.0 mm among treated laypersons, and 1.0 mm among dentists. Non-treated laypersons could not perceive dental midline shifts; however, treated laypersons and dentists perceived them when the shift was ≥ 3.0 mm. Conclusions: Laypersons with and without orthodontic treatment experience and dentists have different perceptions of smile esthetics. Orthodontically treated laypersons were more critical than non-treated laypersons regarding incisal plane canting and dental midline shifts. Based on these findings, it is suggested that orthodontic treatment experience improved the esthetic perceptions of laypersons.

      • 서울市 糞尿處理計劃을 爲한 基礎硏究

        李武康,鄭長杓,金座官 慶星大學校 1990 論文集 Vol.11 No.2

        1. Objectives & Scope of the Study The purpose of this study is (1) to identify & analyze problems of Seoul nightsoil management, and (2) to make policy recommendations for efficient nightsoil management. Even though this study mainly deals with the seoul nightsoil, it approached the problem of Busan nightsoil management. 2. summary & policy recommendations The general results of this study is focused on as follows. 1) the generation rates of nightsoil Raw nightsoil generation rates are 1986 kl/day as 30% of total generation rates 2) collection of nightsoil Raw nightsoil collection efficiency is 94.3%, but on the other hand septic sludge collection efficiency is 72.5%. As the policy Recommendation, Collection rate of 70% is necessary when septic tank sludge is collected. 3) Disposal plan & policy recommendation In the prediction of nightsoil, septic tank sludge generation rates will be increased, and raw nightsoil generation rates will be decreased. For total nightsoil treatment plan, it is necessary to construct anaerobic digestion processing plant in Anyang sewage treatment plant. Therefore, In order to execute nightsoil treatment plan, the current system of nightsoil plant system needs to be modified according to decreasing of nightsoil. After all, nightsoil treatment system will be altered sewage plant system soon, and focused on septic tank sludge disposal for the present.

      • KCI등재

        한국 고유종 미유기 (Silurus microdorsalis Mori, 1936)의 난 발생 및 자치어 형태발달

        김강래 ( Kang-rae Kim ),곽영호 ( Yeong-ho Kwak ),성무성 ( Mu-sung Sung ),양현 ( Heon Yang ),조성장 ( Seong-jang Cho ),윤봉한 ( Bong Han Yun ),방인철 ( In-chul Bang ) 한국어류학회 2023 韓國魚類學會誌 Vol.35 No.2

        The early life history of Silurus microdorsalis living in Jahocheon Stream was studied by observing egg and morphological development. Live fish were captured in June 2018, then reared in a circulating filtration system under a 14L : 10D photoperiod with a water temperature of 18℃. To artificially induce spawning, females were injected with 0.5 mL of Ovaprim (Syndel, Nanaimo, BC, Canada) per kg of body weight, and males were injected with 10,000 IU/kg body weight of human chorionic gonadotropin. Approximately 15 h later, eggs were artificially inseminated by the dry method. Mature eggs were light pale yellow, which separated them from immature eggs. Fertilized eggs were 2.16±0.06 mm (n=8) in diameter and fully hatched at 181 h after fertilization. The fertilization rate was 63.1±2.2%, and 10.0±3.7% of the embryos were malformed at 18℃. The rates of development were 181 h at 18℃, 109 h at 21℃, and 76 h at 24℃. The larval size immediately after hatching was 4.64±0.22 mm (n=8), and the larvae displayed negative phototaxis at 1 day after hatching. The total larval length on 7 days after hatching was 12.47±0.53 mm, with 25~30 basal anal fin rays and 14~16 basal caudal fin rays observed. The total larval length was 14.13±0.51 mm on 9 days after hatching, and approximately 90% of the black endoplasmic reticulum was deposited on the head and body. The dorsal fin had formed, and a single basal body was observed. On 15 days after hatching, the total larval length was 16.69±0.31 mm; the number of basal caudal fin rays (18 poles) was an integer because 2 dorsal fin basal rays and 60~63 anal fin basal rays were observed. The total larval length was 28.96±1.10 mm on 50 days after hatching; the numbers of caudal fins (n=18), dorsal fins (n=3), pectoral fins (n=11), and anal fin basal rays (n=67~73) were integers.

      • 자료 저장소 랩퍼에서 XML 뷰 기반의 XML 스키마 관리 시스템

        정무장(Mu-Jang Jung),박진수(Jin-soo Park),정채영(Chae-yeong Jeong),이미영(Mi-young Lee),강현석(Hyun-syug Kang),배종민(Jong-min Bae) 한국정보과학회 2002 한국정보과학회 학술발표논문집 Vol.29 No.1B

        미디에이터 기반의 데이터베이스 통합 방법론에서 랩퍼는 미디에이터에게 지역 데이터베이스의 스키마를 전달해야 한다. 여기서는 지역 데이터베이스의 스키마를 XML 스키마로 변환하여 미디에이터에게 전달하는 랩퍼 시스템에서의 스키마 관리기에 대하여 논한다. 이를 위하여 관계형 모델의 지역 데이터베이스에서, 지역 데이터베이스 스키마를 XML 스카마로 변환할 때 고려할 사항을 논한다. 그리고 XML 질의어인 XQuery로 XML 뷰 정의 언어를 사용할 때, XQuery로 표현된 XML 뷰를 XML Schema로 표현된 XML 스키마로 변환하는 방법을 제시한다.

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