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생약제제인 이공산(異功散)의 Cisplatin 유도 신장독성 보호 및 항산화 효과
Lee, Kyung-Tae,Ahn, Kyoo-Seok,Chang, Sung-Goo,Oh, Soo-Myung,Jung, Jee-Chang 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1
Kyung-Tae Lee, Kyoo-Seok Ahn¹, Sung-Goo Chang², Soo-Myung Oh²and Jee-Chang Jung²¹College of Pharmacy, ²Oriental Medicine and ³College of Medicine, and East-West Medical Reserch Institute, Kyung Hee University, Seoul, Korea. Preventive and Antioxidative Effects of Crude Drug Preparation(E-kong-san) on Cisplatin Induced Nephrotoxicity. Proceedings of International Symposium on East-West Medicine, Seoul. 201-211, 1999. -Nephroprotective effects of a crude drug-prearation (E-kong-san) were determined from cisplatin on rabbit kidney proximal tubule and human renal cortical cells by MTT assays and sustained glucose consumption on ciplatin-induced human renal cortical tissue. Levels of creatinine and blood ure nitrogen(BUN) in serum after administration of cisplatin(0.75mg/kg,i.p.) to E-kong-san(0.75g/kg/day,p.o.)-pretreated rats were markedly lower compared to those of cisplatin-treated rats. Moreover, the administration of E-kong-san significantly inhibited the loss of body weight of cisplatin injected rts. These findings suggest that E-kong-san on the cisplatin induced nephrotoxicity led us to investigate whether the effect of this water extract was a result of anti-oxidation. E-kong-san showed strong free radical scavenger activities on 1,1-dipheny1-2picrylhydrazil(DPPH) radical and xanthine/xanthine oxidase(XOD) generated superoxide anion radical(O2-). We further studied the effects of E-kong-san on lipid peroxidation in rat liver microsomes induced by enzymatic and nonenzymatic methods. E-kong-san exhibited significant inhibition on both ascorbic acid/Fe2+and ADP/NADPH/Fe3+ induced lipid peroxidation in rat liver microsomes. Based on these results, we suggest that-E-kong-san attenuate the cisplatin induced cytotoxicity and its mechanism can be eplained by antioxidant.
구성태,송문영,강정묵,김용명,박보라,이은석,홍정아,김경식,손인철 한국전통의학연구소 2003 한국전통의학지 Vol.13 No.1
Literally, the mean of Tae-gye is highest brook. And on the basis of the acupuncture theory, Tae-gye point is the Soo earth point and source point of the Kidney Channel as well. In addition, Tae-gye point is one of the Yang-Returning Nine points. We were trying to study bibliographically on the Tae-gye point because Tae-gye point can be used very broadly across the symptoms in the theoretical aspect described above. As a results, we found out that according to the classical books of acupuncture, Tae-gye point is entering point of the Meridian Water as a source point and can be used at both Kidney-Sufficient Syndrom and Kidney-Deficient Syndrom. And Tae-gye can be applied to the disease of kidney or bladder that is urogenital symtoms, Also, Tae-gye is an useful option of tooth-ache, asthma, indigestion, constipation, edema etc whose cause is related with decrease of Kidney ki.
주정 중독 환자에게 Fluoxetine 장기 투여가 음주 욕구에 미치는 영향
강병구,김명정,변원탄 大韓神經精神醫學會 1994 신경정신의학 Vol.33 No.2
Effects of long-term medication of fluoxetine and nortriptyline on alcohol craving in alcoholic patients were studied. The subjects were hospitalized male alcoholics recovered from acute intoxication and withdrawal symptoms. They were divided into placebo, nortriptyline(100㎎), fluoxetine(40㎎) and fluoxetine(60㎎) groups. Alcohol craving was measured at the start, 2 weeks and 4 weeks after medication by means of visual analogue scale, verbal rating scale and the amount of alcohol consumed during the taste test. The results were as follows : 1) Alcohol craving as measured by VAS was significantly reduced after 4 weeks of treatment of nortriptyline. 2) Alcohol craving as measured by VAS was significantly abated after 2 and 4 weeks of treatment of fluoxetine(60㎎). 3) Reduction of alcohol craving by fluoxetine treatment preceded emergence of the antidepressant effect of the drug. From these results, the authors suggest that the reduction of alcohol intake by fluoxetine may be partially due to the reduction of alcohol craving and that the effect may precede the antidepressant effect of the drug.
金正玉,崔外仙,李明嬌,具香淑 효성여자대학교 새마을연구소 1985 새마을硏究論文集 Vol.5 No.-
The purpose of this studyy was to explore conjugal power structitrein urban spouses in order to suggest basic data of family problemsolution. For this purpose, a questionnaire was constructed and administratedto 635 married women. The conjugal power structure scale used a modified version ofdecision making meaure constructed by Blood and wolfe. The results of tis study are summarized as follows : 1. Urban family types by conjugal power structure were establishedas follows: Autonomic type 49.6% syncratic type 32.4%, wife-domi-nant type 12.8%, husband-dominant type 5.2%. 2. Conjugal power structure represented more explict difference atpsychological variables rather than social, demographic statistic,family environmental variables. 3. Marital satisfaction was highest in syncratic type and wife-do-rninant type was lowest. 4. Wife's power was highest for "food preparation" and "purchaseof family clothes," Husband's power was highest for "purchase andsale of housing" "method of property management." 5. The degree of joint decision making between husband and wifewas highest in deciding problem of children.
쏘가리 Siniperca scherzeri 자어기에 있어 초기 기아가 체형 , 생존율 및 공식에 미치는 영향
명정구(Jung Goo Myoung),정철(Chul Jung),한명수(Myung Soo Han),김병기(Pyong Kih Kim),김형배(Hung Bae Kim),최희정(Hi Jung Choi),김민석(Min Suk Kim) 한국수산과학회 1999 한국수산과학회지 Vol.32 No.5
The effect of delayed initial feeding (1, 3, 5, 7 days) and starvation on morphological change, mortality and cannibalism on larvae of Siniperca scheneri was examined by laboratory rearing. The larvae of S. scherzeri began to feed on Artemia nauplii at 4 days after hatching. In case of unfed and 7-days delayed groups, all of the larvae died at 12 days after hatching. The larvae of 1 day delayed feeding survived and grew as almost same as the control group, and 3-days delayed groups showed 33% survival rate at the end of experiment (12 days after hatching). In case of the unfed group, total length of the starved larvae showed lower growth rate than the control group, and they did not reached at the same size of the larvae of the control group. Cannibalism were more common in the unfed group and the delayed fed group than the control group. The highest rate of daily mortality caused by cannibalism in the delayed fed group was 23% at 8 days after hatching.
한국 성인에서 Helicobacter pylori 감염의 진단에 있어 Helicobacter pylori Stool Antigen Test ( HpSA ) 의 진단 정확도
윤종구(Jung Goo Yoon),한석원(Sok Won Han),양성은(Seong Eun Yang),박지찬(Ji Chan Park),이계원(Kye Won Lee),이승규(Seung Kyu Lee),김명철(Myung Cheol Kim),김상우(Sang Woo Kim),김진일(Jin Il Kim),최명규(Myung Kyu Choi),한남익(Nam Ik Han) 대한소화기학회 2002 대한소화기학회지 Vol.40 No.2
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