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      • 젊은 남자에게 발생한 통상성 간질성 폐렴과 동반된 폐암 1예

        박종숙,이준혁,박성우,장안수,박춘식,박재성,백상현,고은석,신화균 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

        Usual interstitial pneumonia(UIP) is relatively rare disease of lung parenchyme under the age of 50. Lung cancer is reported to occur as a complication of UIP, but has not been reported in young age patient with UIP in Korea. A 35-year-old man was admitted to the hospital because of dyspnea, cough and mild fever. He had been suffered from dyspnea during 3 years. The dyspnea worsened recent 1 month ago. He had been treated with pneumonia at another hospital during 4 months before this admission. Chest radiographs and High resolution CT showed subpleural and basal dominant reticular opacities in both lung with no change until now. He was smoker and his occupation was car engine-man dealing with benzene. UIP is suspected by history and radiologic findings. Operation for open lung biopsy was performed to obtain lung specimen via video-assisted thoracoscopic surgery. Patient's pathologic examination showed UIP combined with adenocarcinoma in RLL superior segment and posterobasal segment and RLL lobectomy was done. After operation, the patient has been in cancer free condition so far. We report a case of UIP combined with lung cancer in young man with brief review of the literature.

      • KCI등재
      • SCOPUSKCI등재

        김치유래 젖산균의 균체지방산 분석을 이용한 분류학적 연구

        이정숙,정민철,김우식,이근철,김홍중,박찬선,이헌주,주윤정,이근종,안종석,박완,박용하,민태익 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.2

        표준균주를 포함한 230여개의 김치유래 젖산균에 대한 균체지방산(FAMEs)을 분석하였다. FAMEs profiles는 Euclidian Distance 17.5에 의해 7개의 Major Cluster와 1개의 Single Cluster로 나뉘어졌다. 이중 A, B, C 및 Cluster는 Leuconostoc속으로 분석되어졌고, F는 Lactobacillus속으로 분석되어졌다. 그리고 E와 G cluster는 두개의 Genus가 혼재되어 나타났으며 보충적인 연구가 필요하다. 앞으로 김치유래 젖산균의 균체지방산 분석결과를 기반으로 한 데이타베이스에 95가지 탄소원을 이용하는 수치분류학적 접근방법 및 Pyrolysis Mass Spectrometry 등의 화학적 분석 방법과 분자친화적 연구를 통한 종합적 분류정보 체계가 갖추어지면 젖산균의 신속, 정확한 동정 및 연구에 활발히 이용되어질 것이다. Two hundreds and thirty lactic acid bacteria, mostly isolated from Kimchi, including type strains were sued for analysis of cellular fatty acids. The 230 test strains were recoverd in 7 major and 1 single clusters defined a Euclidian distance of 17.5. These aggregate taxa were equivalent to the genus Leuconostoc (aggregate group A, B, C and D), and the genera Leuconostoc and Lactobacillus (aggregate group G). It is concluded as evident that FAMEs (Fatty Acid Methyl Esters) profile of cell can be used as a criterion in classification of lactic acid bacterial from kimchi. Additional comparative taxonomic studies need to be carried out on well chosen representative strains to determine the most appropriate methods of value.

      • TiO_(2)-SiO_(2) 나노 복합미립자의 합성

        박진구,송영상,김종길,김호건 한양대학교 이학기술연구소 2005 이학기술연구지 Vol.8 No.-

        TEOS(tetrethyl orthosilicate)로 부터 제조된 구형의 SiO_(2) 미립자를 TiOCl_(2) 수용액과 반응시켜 SiO_(2) 표면에 10~20㎚ 두께의 균일한 TiO_(2)막이 형성된 TiO_(2)-SiO_(2) 복합미립자를 합성하였다. X-선 회절 분석결과 합성초기의 복합체 TiO_(2)는 비정질 상태이지만 700℃이상의 열처리에 의하여 anatase결정상이 나타났고 900℃이상에서 rutile결정상으로 전이됨을 확인하였다. TiO_(2)-SiO_(2) composite particle in which the homogeneous TiO_(2) layer with width of 10~20㎚ was formed on the SiO_(2) surface by the reaciton of the spherical SiO_(2) particale in TiOCl_(2) solution As the resulte of XRD analysis the phase of TiO_(2) coated on SiO_(2) sphere was noncrystalline state however it was changed to anatase crystal state by heating at 700℃and th anatase phase was transfomed to reile phase at the aboce 900℃

      • 교통사고에 의해 발생한 뇌내 좌상 1례

        박혜연,전소분,김선아,정금선,조종기,송근호,이영원 충남대학교 수의과대학 동물의과학연구소 2004 動物醫科學硏究誌 Vol.12 No.-

        A two years old intact female Minature Schnauzer was referred to the Veterinary Medical Teaching Hospital of Chungnam National University with an intermittent seizure by traffic accident. No specific finding was found by radiography and computer tomography (CT). Hematologic and blood chemical examination revealed that PCV (62.5%), BUN (72.6 mg/dl), CK (1769 U/l), ALT (169 U/l) and ALP (353 U/l) were increased. This dog was recovered by medical treatment.

      • 人蔘脂溶牲 成分이 四鹽化炭素 投與 白鼠의 蛋白質代謝에 미치는 影響

        朴鍾培,柳總根 고려대학교 의과대학 1984 고려대 의대 잡지 Vol.21 No.1

        In order to observe a part of the effect of Ginseng fat soluble components (Gx) on the protein metabolism under CCI₄ poisoning, 192 male and female albino rats were taken as subjects which were divided into 6 experimental groups i.e. control grop; CCI₄ group which were observed after CCI₄ and been administered only one time; Gx group which were observed administering Ginseng one time daily; CCI₄+Gx group which were observed administering Ginseng one time daily after CCI₄ had been administered, Gx+CCI₄ group to which CCI₄ was administered only on time after Ginseng had been administered 6 times; and Gx_CCI₄+Gx group to which Ginseng was administered one time daily after CCI₄ had been administered following a 6th time administration of Ginseng. Programed administrations of Ginseng or CCI₄ were given to each corresponding groups at several periods i.e. 1,2,4,6 and 8 days after the intial administration of given doses, changes of total protein, albumin, globulin, urea nitrogen, transaminase (GOT) of serum and total nitrogen observed at each period were measured and the results obtained are as follows: 1. Gx administration was found to have the ability to decrease the elevated SGOT activity resulting from administration of CCI₄ and induce rapid recrovery from such an elevated level and the extent of such a dereasing action was greatest in Gx+CCI₄+Gx group, than Gx+CCI₄ group, and the least in CCI₄+Gx group. 2. Gx+CCI₄+Gx group showed nearly no change in serum albumin level, and being in second place, Gx administering groups (CCI₄+Gx group, Gx+CCI₄ group) showed small change. 3. Gx administering groups showed more increase in globulin level at 1-2 day period than the CCI₄ group and during the same period A/G ratio was found inverted. 4. Total nitrogen amount in the liver was remarkably decreased in Gx administering groups at 2 day period. 5. Urea nitrogen was increased in CCI₄ group at 2 day period, whereas Gx administering groups showed decreases. 6. Great changes in electrophoresis fractions were found in α₁-and r-globulin fractions at 1-2 day period. For more detail a. α₁-globulin; Gx administering groups showed lower increases than the CCI₄ group at 2 day period. b. r-globulin; Gx_CCI₄ group and CCI₄+Gx group showed more increases than the CCI₄ group at 1-2 day period. 7. α₂-globulin, revealing characteristic pattern, was increased to the same extent in all the Gx administerings groups during Gx administering period, thus Gx was estimated to increase the α₂-globulin component.

      • 家族計劃에 依한 出生抑制兒數 推定

        朴仁和,金正根 서울大學校 保健大學院 1978 보건학논집 Vol.15 No.1

        The purpose of thos study is to estimate births averted and to measure impact on fertility by family planning programs. The data used in this study were collected from 'the Community Pregnancy Study'in three Myons of Chunseong Gun, Kangwon Province, during the period from May 1973 to April 1976. 1,246 cases practicing one other methods of contraception among 3,630 fecund women, who were under surveillance by the cohort study, were the objects of this study. In this analysis, estimated number of births averted was performed, especially upon the acceptors of IUD, by the Model developed by potter(1969). The analysis was carried out separately for five age groups: under 25, 25-29 30-34, 35-39, and 40 and over, Results for the total population were derived as weighted averages of age-specific results. The results were as follows: (1) R: Mean span of useful retention of IUD, using 'PER' (Pregnancy, Expulsion, Removal) and 'Mortality' as competing risks, was 20.1 months. (2) I: Mean length of interruption of childbearing by each IUD inserted allowing for the overlap between IUD retention and amenorrhea (A), and the effect of accidental pregnancies (PW), was 16.7 months. (3) The allocation of useful retention of IUD to successive years following insertion: After initial year, the number of births averted was declined. This decline was more rapid in the younger age group, due to the shorter retention span of IUD. Therefore, exception might be taken to Chow's allegation that “impact from IUD will be fairly uniform over the 5 years following insertion.” (4) The level of potential fertility without contraception: Potential fertility cannot be measured directly from 'Age-Specific Marital Fertility Rate of total women belonging to the same age group. In this analysis, the estimate of D was based on the acceptors own experiences for pregnancy. D: The mean length of the birth interval in the absence of contraception was 40 months. (5) The number of births averted by the segment of IUD was 0.36, which was measured by the ration of I to D. The effectiveness of birth averted by age group was better in the younger age group than that of the older. This Supported Lee and Isbister's generalization that “more is accomplished by securing younger participants in an IUD program” (6) In the application of the Potter's Models the most important parameters for the estimation of births averted were thought to be R, the typical lenght of retention and D, the degree of potential fertility. Consequently, the demographic effectiveness of contraceptive in a given population depends on R and D. (7) The total mumber of births averted during the period of this study was estimated as 359 by all contraceptives. The IUD, which contributed to 45 percent of total number of birth averted, was superior to other methods. (8) The impact on 'Fertility Rate' during this study was 16 percent decrease when compared with 'the Expected Fertility Rate' in the absence of family planning programs.

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