Treatment and Follow-up of Human Papillomavirus Infected Women in a Municipality in Southern Brazil

Ruggeri, Joao Batista,Agnolo, Catia Millene Dell,Gravena, Angela Andreia Franca,Demitto, Marcela de Oliveira,Lopes, Tiara Cristina Romeiro,Delatorre, Silvana,Carvalho, Maria Dalva de Barros,Consolaro, Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.15

Background: This study aimed toanalyze the risk behavior for cervical cancer (CC) and the human papillomavirus (HPV) prevalence and resolution among women who received care through the private healthcare network of a municipality in southern Brazil. Materials and Methods: This descriptive and retrospective study was conducted with 25 women aged 20 to 59 years who received care through the private healthcare network and were treated at a specialty clinic in the period from January to December 2012 in a municipality in Northwest Parana, Southern Brazil. Data from medical records with cytological and HPV results were used. Following treatment, these women were followed-up and reassessed after 6 months. Data were statistically analyzed using the t-test and chi-squared test at a 5% significance level. Results: The mean age of the studied women was $27.8{\pm}7.75$ years old, and the majority were married, with paid employment and were non-smokers. The mean age at menarche was $13.0{\pm}0.50$ years old, and the mean age at first intercourse was $17.5{\pm}1.78$ years, with only 8.0% (2) initiating sexual activity at an age ${\leq}15$ years old. The majority had 1 to 2 children (60.0%), while 88.0% reported having had one sexual partner in their lifetime, and all the women were sexually active. A total of 68.0% used a hormonal contraceptive method. All the women had leukorrhea and pain and were infected by a single HPV type. Regarding the lesion grade, 80.0% showed high risk and 20.0% low risk. The most prevalent high-risk HPV strain was 16. Conclusions: These findings provide relevant information on HPV risk factors and infection, as well as the treatment and 6-month follow-up results, in economically and socially advantaged women with no traditional risk factors, corroborating previous reports that different risk factors may be described in different populations. Thus, this study reinforces the fact that even women without the traditional risk factors should undergo HPVmonitoring and assessment to determine the persistence of infection, promoting early diagnosis of the lesions presented and appropriate treatment to thus prevent the occurrence of CC.

Comparison of condylar displacement between three biotypological facial groups by using mounted models and a mandibular position indicator

Maria Joao Ponces,Jose Pedro Tavares,Jorge Dias Lopes,Afonso Pinhao Ferreira 대한치과교정학회 2014 대한치과교정학회지 Vol.44 No.6

Objective: Facial-type?associated variations in diagnostic features have several implications in orthodontics. For example, in hyperdivergent craniofacial types, growth imbalances are compensated by displacement of the condyle. When diagnosis and treatment planning involves centric relation (CR), detailed knowledge of the condylar position is desirable. The present study aimed to measure condylar displacement (CD) between CR and maximum intercuspation in three facial types of an asymptomatic orthodontic population. Methods: The study was conducted in 108 patients classified into three groups of 36 individuals each (27 women and 9 men; mean age, 20.5 years), based on the following facial patterns: hyperdivergent, hypodivergent, and intermediate. To quantify CD along the horizontal and vertical axes, the condylar position was analyzed using mounted casts on a semi-adjustable articulator and a mandibular position indicator. The Student t-test was used to compare CD between the groups. Results: Vertical displacement was found to be significantly different between the hyperdivergent and hypodivergent groups (p < 0.0002) and between the hyperdivergent and intermediate groups (p < 0.0006). The differences in horizontal displacement were not significant between the groups. In each group, vertical CD was more evident than horizontal displacement was. Conclusions: All facial types, especially the hyperdivergent type, carried a significantly high risk of CD. Therefore, the possibility of CD should be carefully evaluated and considered in the assessment of all orthodontic cases in order to accurately assess jaw relationships and avoid possible misdiagnosis.

Shaping ability and apical debris extrusion after root canal preparation with rotary or reciprocating instruments: a micro-CT study

da Silva Emmanuel João Nogueira Leal,de Moura Sara Gomes,de Lima Carolina Oliveira,Barbosa Ana Flávia Almeida,Misael Waleska Florentino,Lacerda Mariane Floriano Lopes Santos,Sassone Luciana Moura 대한치과보존학회 2021 Restorative Dentistry & Endodontics Vol.46 No.2

Objectives: The aim of this study was to evaluate the shaping ability of the TruShape and Reciproc Blue systems and the apical extrusion of debris after root canal instrumentation. The ProTaper Universal system was used as a reference for comparison. Materials and Methods: Thirty-three mandibular premolars with a single canal were scanned using micro-computed tomography and were matched into 3 groups (n = 11) according to the instrumentation system: TruShape, Reciproc Blue and ProTaper Universal. The teeth were accessed and mounted in an apparatus with agarose gel, which simulated apical resistance provided by the periapical tissue and enabled the collection of apically extruded debris. During root canal preparation, 2.5% sodium hypochlorite was used as an irrigant. The samples were scanned again after instrumentation. The percentage of unprepared area, removed dentin, and volume of apically extruded debris were analyzed. The data were analyzed using 1-way analysis of variance and the Tukey test for multiple comparisons at a 5% significance level. Results: No significant differences in the percentage of unprepared area were observed among the systems (p > 0.05). ProTaper Universal presented a higher percentage of dentin removal than the TruShape and Reciproc Blue systems (p < 0.05). The systems produced similar volumes of apically extruded debris (p > 0.05). Conclusions: All systems caused apically extruded debris, without any significant differences among them. TruShape, Reciproc Blue, and ProTaper Universal presented similar percentages of unprepared area after root canal instrumentation; however, ProTaper Universal was associated with higher dentin removal than the other systems.

Poster Session:PS 0557 ; Oncology : Massive Bleeding as the First Clinical Manifestation of Metastatic Prostate Cancer Due to Primary Fibrinolysis, Successfully Treated with Aminocaproic Acid

( Monica Palma Anselmo ),( Gustavo Nobre De Jesus ),( Joao Madeira Lopes ),( Rui M M Victorino ),( Joao Meneses Santos ) 대한내과학회 2014 대한내과학회 추계학술발표논문집 Vol.2014 No.1

Disseminated intravascular coagulation (DIC) is the most frequent coagulation disorder associated with metastatic prostate adenocarcinoma. However, DIC as an initial presentation of prostate cancer with primary fi brinolysis is extremely rare. The appropriate treatment to control bleeding in these situations is challenging, controversial and based on isolated case reports in the literature. A 66-year-old male presented at the emergency department with acute severe spontaneous ecchymoses localized to the limbs, latero-cervical hematoma and hemothorax. Prostate specifi c antigen level was 385 μg/L, bone scintigraphy revealed multiple bone metastases and prostate biopsy confi rmed adenocarcinoma (Gleason 9; 4+5). Laboratory investigation showed a pattern of primary fi brinolysis rather than the more common intravascular coagulation mechanism. Epsilon aminocaproic acid in monotherapy was initiated with a clear and rapid control of bleeding manifestations. This rare case of massive bleeding due to hyperfi brinolysis as the fi rst manifestation of prostate cancer suggests that in selected cases where the acute bleeding dyscrasia is clearly associated to a dominant fi brinolysis mechanism it is possible to use an approach of monotherapy with antifi brinolytics.

Transmission of Methylobacterium mesophilicum by Bucephalogonia xanthophis for Paratransgenic Control Strategy of Citrus Variegated Chlorosis

Cláudia Santos Gai,Paulo Teixeira Lacava,Maria Carolina Quecine,Marie-Christine Auriac,João Roberto Spotti Lopes,Welington Luiz Araújo,Thomas Albert Miller,João Lúcio Azevedo 한국미생물학회 2009 The journal of microbiology Vol.47 No.4

Methylobacterium mesophilicum, originally isolated as an endophytic bacterium from citrus plants, was genetically transformed to express green fluorescent protein (GFP). The GFP-labeled strain of M. mesophilicum was inoculated into Catharanthus roseus (model plant) seedlings and further observed colonizing its xylem vessels. The transmission of this endophyte by Bucephalogonia xanthophis, one of the insect vectors that transmit Xylella fastidiosa subsp. pauca, was verified by insects feeding from fluids containing the GFP bacterium followed by transmission to plants and isolating the endophyte from C. roseus plants. Forty-five days after inoculation, the plants exhibited endophytic colonization by M. mesophilicum, confirming this bacterium as a nonpathogenic, xylem-associated endophyte. Our data demonstrate that M. mesophilicum not only occupy the same niche of X. fastidiosa subsp. pauca inside plants but also may be transmitted by B. xanthophis. The transmission, colonization, and genetic manipulation of M. mesophilicum is a prerequisite to examining the potential use of symbiotic control to interrupt the transmission of X. fastidiosa subsp. pauca, the bacterial pathogen causing Citrus variegated chlorosis by insect vectors.

A review of properties, nutritional and pharmaceutical applications of Moringa oleifera: integrative approach on conventional and traditional Asian medicine

Diana Meireles,João Gomes,Lara Lopes,Mariana Hinzmann,Jorge Machado 경희대학교 융합한의과학연구소 2020 Oriental Pharmacy and Experimental Medicine Vol.20 No.4

Moringa oleifera L. from the Moringaceae family is a perennial tree widely cultivated in many tropic regions and easily grown even in adverse conditions. M. oleifera is also known as the miracle tree, which for centuries has been indicated for traditional medicine. With no reports of side effects, in doses achievable by ingestion, different parts of M. oleifera is used to treat several conditions, such as malnutrition, diabetes, blindness, anemia, hypertension, stress, depression, skin, arthritis, joints and kidney stones disorders. This plant also showed capacity of helping in maintenance of the cardiovascular system health, blood-glucose levels and providing anti-oxidant, anti-inflammatory and anti-cancer activity as well as the regulation of urinary tract and lactation in nursing women. The seed and leaves powder has water purification properties through flocculation. It also supplements the food in the human diet and in the fortification of livestock feed, especially in developing countries. So, M. oleifera properties have also been applied to cosmetic and byproducts industries due to the high nutritive and protective properties of its seed oil. According to the holistic or traditional medicine, M. oleifera has very relevant therapeutic properties and applications depending on the constitution, somatic and psychological needs of patients. It is usually referred as a natural product that can treat different physical and psychological health aspects, offering an energetic action and structural rebuilder of the body and promoting emotions of highly positive attitudes towards life. The high and specific immunological potential of M. oleifera leads us to suggest an in-depth study to assess the hypothesis of conferring a supportive effect against Covid-19 disease.

Extracting Translation Equivalents from Portuguese - Chinese Parallel Texts

Ribeiro, Antonio,Lopes, Gabriel,Mexia, Joao 연세대학교 언어정보개발원 2001 사전편찬학 연구 Vol.11 No.1

In this paper we will present a method of extracting translations equivalents from Chinese-Portuguese parallel texts. The parallel texts are aligned using a statistically based method which recurs to no heuristics and does not assume any a priori knowledge of both languages. We extract multiword units, or multicharacter units for the case of Chinese, in order to capture recurring patterns of words or characters. Then we extract translation equivalents by looking for patterns of words which tend occur in the same aligned text segments using a similarity measure. Finally, the extracted translation equivalents are reused as additional points of correspondence between parallel texts of both languages in order to further extract other translation equivalents and enhance the quality of the alignment.

Extracting Translation Equivalents from Portuguese - Chinese Parallel Texts

(Antonio Ribeiro),(Gabriel Lopes),(Joao Mexia) 연세대학교 언어정보연구원 2001 제 2 차 아시아 사전학회 국제 학술대회 Vol.- No.-

N/A

The Ketone Bridge Between the Heart and the Bladder: How Fast Should We Go?

Gabriel Faria-Costa,João Oliveira,Inês Vilas-Boas,Inês Campelo,Elisa Azeredo Silva,Carmen Brás-Silva,Susana Maria Silva,Tiago Antunes-Lopes,Ana Charrua 대한배뇨장애요실금학회 2024 International Neurourology Journal Vol.28 No.-

Metabolic syndrome (MS) is associated with both cardiovascular and bladder dysfunction. Insulin resistance (IR) and central obesity, in particular, are the main risk factors. In these patients, vicious pathological cycles exacerbate abnormal carbohydrate metabolism and sustain an inflammatory state, with serious implications for both the heart and bladder. Ketone bodies serve as an alternative energy source in this context. They are considered a “super-fuel” because they generate adenosine triphosphate with less oxygen consumption per molecule, thus enhancing metabolic efficiency. Ketone bodies have a positive impact on all components of MS. They aid in weight loss and glycemic control, lower blood pressure, improve lipid profiles, and enhance endothelial function. Additionally, they possess direct anti-inflammatory, antioxidant, and vasodilatory properties. A shared key player in dysfunction of both the heart and bladder dysfunction is the formation of the NLRP3 inflammasome, which ketone bodies inhibit. Interventions that elevate ketone body levels—such as fasting, a ketogenic diet, ketone supplements, and sodium-glucose cotransporter 2 inhibitors—have been shown to directly affect cardiovascular outcomes and improve lower urinary tract symptoms derived from MS. This review explores the pathophysiological basis of the benefits of ketone bodies in cardiac and bladder dysfunction.

Mechanical Properties of Alumina Nanofilled Polymeric Composites Cured with DDSA and MNA

Ana M. Amaro,Deesy G. Pinto,Luís Bernardo,Sérgio Lopes,João Rodrigues,Cristina S. Louro 한국섬유공학회 2018 Fibers and polymers Vol.19 No.2

Reinforced concrete is widely used in structures. New materials to replace both the steel and the concrete have been studied in many research centres. One of the possibilities for the reinforcement is the partial or total replacement of the steel bars by new composite materials. Nano composites are very promising, and an investigation line was developed to this end by an interdisciplinary team. On this work, the mechanical properties of epoxy resin nanocomposites (EPNCs) filled with α-Al2O3 nanoparticles (NPs) with irregular shape and approximately 100 nm maximum diameter size was investigated. The variable study was the alumina NPs contents: 1, 3 and 5 wt.%. The NPs were previously pretreated with a silane agent (APTES). Two hardeners, 3-dodec-2-enyloxolane-2,5-dione (DDSA) and 8-methyl-3a,4,7,7a-tetrahydro-4,7-methano-2- benzofuran-1,3-dione (MNA), frequently used in epoxy resin embedding tissues, were used simultaneously for this study. Unlike other hardeners, DDSA does not need curing treatment, constituting a novel application and a saving time-energy during the manufacturing process. Considering the mechanical behaviour, it was observed that the EPNCs filled with 5 wt.% of alumina NPs showed the maximum improvement in flexural modulus, around 14 % when compared to the pristine EP sample. No relevant effect was observed on the flexural strength by adding alumina NPs. Additionally, the maximum increase observed for hardness, and Young’s modulus were about 13 % and 28 %, respectively (the maximum increase was observed at 3 wt.%).