Antipredator behavior to the chemical cue of potential predators in Korean clawed salamander larvae (Onychodactylus koreanus)

Jiyeon Cheon,Jongsun Kim,Hyerim Kwon,Jiho Park,Daesik Park 한국양서ㆍ파충류학회 2023 한국양서·파충류학회 학술대회 Vol.2023 No.07

Korean clawed salamander larvae (Onychodactylus koreanus) mainly inhabit mountain valleys, unlike other Hynobius salamanders. This study aimed to reveal if predation pressure affects the distribution of O. koreanus larvae in the valleys through olfactory antipredator behavior tests. In summer, the larvae move downstream that increasing the chance of encountering potential fish predators. So, we wanted to know if antipredator behavior is acquired while first experiencing the predators or innate. First, we investigated the response of O. koreanus larvae to chemical cues (100%, 50%, 25%, and 0%) of crayfishes (Cambaroides similis) and minnows (Rhynchocypris oxycephalus). Second, after learning twice by mixing the target species and potential predators' chemical cues, we tested if antipredator behavior is shifted. Onychondactylus koreanus showed significant antipredator response to minow odors by reducing moved time and distance, but not to crayfish odors. In the second test, the larvae showed significant antipredator behavior regardless of whether they had learned about the predator or not. Our results demonstrate that minnows are potential predator of O. koreanus larvae and potentially affect the restriction of distribution of the larvae in the valleys. In addition, the second result suggests that antipredator response of O. koreanus to minow odors is innate.

The Role of Ethnic Socialization, Ethnic Identity and Self-Esteem: Implications for Bi-ethnic Adolescents’ School Adjustment

Lee, Jiyeon,Cheon, Yuen Mi,Wei, Xinying,Chung, Grace H. Springer-Verlag 2018 Journal of child and family studies Vol.27 No.12

관상동맥질환자의 D유형 성격과 치료지시이행의 관계에 미치는 극복력의 매개효과

천미영(Cheon, Mi Young),강지연(Kang, Jiyeon) 한국성인간호학회 2016 성인간호학회지 Vol.28 No.1

실시간 용접데이터를 이용한 Tandem GMW 용접부 비드 형상 예측 모델 개발

심지연(Jiyeon Shim),천현필(Heonpil Cheon) 한국자동차공학회 2023 한국자동차공학회 학술대회 및 전시회 Vol.2023 No.11

20대 소비자에게 벼룩시장 및 중고품의 의미는 무엇인가?

천혜정(Hyejung Cheon),이지연(Jiyeon Lee) 한국유통학회 2015 流通硏究 Vol.20 No.3

본 연구에서는 중노년의 장소로 알려진 황학동/동묘 벼룩시장을 20대 소비자가 왜 찾으며 이 시장에서 어떠한 경험을 하는지, 그리고 20대 소비자에게 벼룩시장 및 중고품의 의미는 무엇인지를 살펴보고자 한다. 이를 위해 황학동/동묘 벼룩시장을 방문, 중고품을 구매하는 20대 소비자 8명과의 개인면접을 실시하였다. 연구결과 20대 소비자는 황학동/동묘 벼룩시장에서 자신이 어렸을 때 가지고 놀거나 사용하던 물건이지만 이제는 현대화된 시장에서 쉽게 발견할 수 없는 물건들을 통해 과거를 추억하는데, 이들에게 추억 ‘돋는’ 물건은 도스형 컴퓨터, 디스켓, 게임팩, 장난감, 워크맨, 비디오테이프등으로 다양하였다. 그런데 이들이 시장의 물건을 보며 느끼는 기억은 과거에 의존하고 있지만 기억을 통해 상기되는 과거의 것들은 현재의 상태를 지시하고 있었다. 즉 한국사회의 20대로서 자신들이 직면한 불안한 현실보다 위협적이지 않고 편안했던 과거를 돌아볼 수 있는 곳으로 황학동/동묘 벼룩시장을 경험하며 승자독식의 현대사회에서 시골생활의 낭만을 느낄 수 있는 힐링의 장소로 황학동/동묘 벼룩시장에 대한 가치를 부여하고 있었다. 또한 마구잡이로 쌓여있는 물건들, 갈 때마다 바뀌는 물건들, 허를 찌르는 물건들에 대한 호기심을 이야기하는 등 ‘탐험가’로서의 소비자의 모습을 띠고 있었으며 자신이 원하는 물건을 저렴하게 구매하는 이른바 ‘득템’의 즐거움을 경험한다. 이들은 중고품에 대한 거부감을 전혀가지지 않으며, 오히려 보물찾기, 빈티지 등의 용어를 사용하며 세월의 흔적을 느낄 수 있는 중고품에 매력을 느낀다고 하였다. 현대화된 백화점과 쇼핑몰, 합리화/대형화된 유통점과 편의점 등에 보다 익숙한 20대 소비자들이 오히려 허름하고 낡은 벼룩시장의 날 것 그대로의 모습에 의미를 부여하고 있다는 것은 매우 흥미로운 지점이다. 결국 중고품과 벼룩시장에서의 소비경험을 이해하기 위해서는 중고품과 벼룩시장이 가지는 기본적인 경제적 기능 이외 사회문화적 가치까지 재고할 필요가 있음을 보여주고 있었다.

Compressive Properties of Nanoporous Gold Through Nanoindentation: An Analytical Approach Based on the Expanding Cavity Model

Oh Min Kwon,Jiyeon Kim,Jinwoo Lee,Jong‑hyoung Kim,Hee‑Jun Ahn,Ju‑Young Kim,Young‑Cheon Kim,Dongil Kwon 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.10

We investigated the analytic relation between hardness and compressive yield stress using an expanding cavity model (ECM)for nanoporous gold (np-Au). We prepared three np-Au samples with ligament sizes 30.61, 59.36 and 116.33 nm by freecorrosiondealloying and post heat treatment. The indentation contact morphology was examined to estimate the hardnessaccurately from the nanoindentation load-depth curve. Unlike conventional dense metals, the deformation was confined to theprojected contact area, and the center of the residual impression was dominated by densification. The projected contact areaestimated by the Oliver–Pharr method was overestimated, so that a new contact area function was proposed that consideredthe indentation contact morphology of np-Au. It was confirmed that a hardness value taking into account the indentationcontact morphology of np-Au matches well with the hardness derived by direct measurement of the residual impression. We modeled the ratio of hardness to compressive yield stress for np-Au using an ECM. The scaling factors, which representthe extra strain-hardening in the core in the ECM, were analyzed for np-Au and dense metals. An ECM that better matchesnp-Au is suggested based on the scaling factor resulting from densification beneath the indenter.

OB-40 : Isolation and Characterization of Chorionic Mesenchymal Stromal Cells from Human Full Term Placenta

( Hye Jung Yun ),( Ju Young Cheon ),( Narinay Kim ),( In Yang Park ),( Bo Kyung Koo ),( Jiyeon Kim ),( Ji Hyun Kim ),( Ahlm Kwon,),( Myungshin Kim ),( Yonggoo Kim ),( Jong Chul Shin ),( Jong Hoon Kim 대한산부인과학회 2014 대한산부인과학회 학술대회 Vol.100 No.-

목적: Adult stem cells are considered as an excellent source for research because they pose few ethical problems and limitations in terms of availability. Although many types of stem cells are available, the sources of the stem cells selected for clinical use should possess the ability to renew, be easily isolated and be pluripotent. These properties can be satisfied with human term placental-derived stromal cells. It is essential to understand the expansion capability and potency of isolated stem cells. 방법: This study focused on the characterization of mesenchymal stromal cells (MSCs) from the chorion of human full term placenta from 15 donors.We characterized the surface markers and multilineage differentiation (adipogenic, osteogenic and chondrogenic induction) ability of cultured chorionic MSCs. We also present our findings regarding their growth rate and gene expressions. 결과: Chorionic MSCs revealed homologous fibroblast-like morphology and expressed CD73, CD29, CD105, and CD90. The hematopoietic stem cell markers including HLA DR, CD11b, CD34, CD79a, and CD45 were not expressed. The growth kinetics of their serial passage was steady at the later passages (passage 10). The multilineage capability of chorionic MSCs was demonstrated by successful adipogenic, osteogenic and chondrogenic differentiation and associated gene expression. Chorionic MSCs expressed genes associated with undifferentiated cells (NANOG, OCT4, REX1) and cardiogenic or neurogenic markers such as SOX2, FGF4, NES, MAP2, and NF. TERT was negative in all the samples. 결론: A low HLA DR expression suggests that chorionic MSCs may serve as a great source of stem cells for transplantation because of their immune- privileged status and their immunosuppressive effect. Based on these unique properties, it is concluded that chorionic MSCs are pluripotent stem cells that are probably less differentiated than BM-MSCs, and they have considerable potential for use in cell-based therapies.

기술성장모형에 기반을 둔 기술수준평가 결과 및 시사점

한민규(Min-Kyu Han),김병수(Byoung Soo Kim),유지연(Jiyeon Ryu),변순천(Soon Cheon Byeon) 한국기술혁신학회 2010 기술혁신학회지 Vol.13 No.2

2008년 기술수준평가 대상기술 중 하나인 ‘바이오칩ㆍ센서기술’은 바이오 분야의 중점과학기술로서 세 가지 세부기술로 구성되어있다. 본 평가에서는 앞선 다른 수준평가의 한계를 극복하기 위하여 델파이와 함께 동태적 방법론(기술성장모형)을 분석틀로 사용하였다. 그 결과 바이오칩ㆍ센서기술은 ‘궁극의 기술’을 기준으로 한국 51.5%, 최고선진국(미국) 75.1%, 두 국가의 기술격차는 6.1년으로 분석되었으며, 5년 후에는 각각 60.1%, 78.4%, 4.3년이 될 것으로 예측되었다. 바이오 분야의 다른 기술과 비교했을 때, 해당 기술은 수준격차가 상대적으로 작았으며, 격차 역시 빠르게 좁혀질 것으로 나타났다. 이러한 특징은 세부기술 수준에서도 마찬가지였다. 설문 분석 결과 해당 기술의 강점은 전문인력 및 연구자금의 효과에 기인하는 것으로 나타났으며, 기초지원의 미비가 취약한 측면으로 지적되었다. 그 외에 이 기술이 상대적으로 신흥 분야이며, 집중적인 연구 활동이 이뤄지고 있다는 점 역시 높은 기술 수준의 요인으로 볼 수 있다. 따라서 바이오칩ㆍ센서 기술의 발전을 위해서는 이러한 강점을 더욱 지원하고, 약점을 보완하는 정책 방안이 필요할 것이다. In this paper, we analyze the result of the Technology Level Evaluation of ‘Biochip and biosensor (BB) Technology’ consisted of 3 sub-categorized technologies; biochip sensing (BS), lab on a chip and high-efficient customized health care technology. As an analysis tool, authors used a delphi (a repeated survey) and dynamic methodology with technology growth model to overcome limits of previous evaluations. As a result, levels of BB were evaluated 51.5% (Korea) and 75.1% (US), and the technology gap between two countries was 6.1 yrs. In 2013, these levels were expected to change to 60.1% (Korea), 78.4% (US) and 4.3 yrs, respectively. In comparison with other biotechnology, the gap of BB was smaller and expected to catch up with US faster. In the case of sub-categorized technologies, they showed the smallest gap and would have faster catch-up speed than other sub-categorized technologies in the Biotechnology field. Based on the result of the survey, relative superiority of BB in Korea was originated from competent researchers and research fund, but weak basic science would be weak points. We think that BB’s characteristic as an emerging technology and concentrated research activities on BB are additional strong points. This research proposes the supporting and supplemented points to promote the BB in Korea.

The Extract of Kochia scoparia Fruit Induces Programmed Necrosis in Oral Squamous Cell Carcinoma Cells

Hye-Yeon Han,Bong-Soo Bark,Hyung Joon Kim,Seung-Hwa Jeong,Jiyeon Kim,Sung-Hee Jeong,Gyoo Cheon Kim,Dae-Seok Hwang,Uk-Kyu Kim,Hyungwoo Kim,Mi Heon Ryu 대한구강악안면병리학회 2016 대한구강악안면병리학회지 Vol.40 No.6

The fruit of Kochia scoparia Scharder is traditionally used as a medicinal ingredient to treat allergic skin diseases and inflammatory diseases in China, Japan and Korea. Recently, several studies reported that K. scoparia had potential for the cytotoxicity of human cancer cells. To investigate the anti-cancer effect of K. scoparia on oral cancer and to determine the specific type of cell death induced by MEKS treatment. We investigated the anti-cancer effects of K. scoparia, methanol extract (MEKS) in HSC4 human oral cancer cells. We examined the effects of MEKS on the proliferation rate, cell cycle arrest, 7-AAD-ANNEXIN V double stain, reactive oxygen species (ROS) generation and activation of apoptosis and necroptosis-associated proteins in HSC4 cells. MTT assay results demonstrated that MEKS decreased the proliferation rates of HSC4 cells in a dose-dependent manner with an IC50 value of 45.3 μg/ml. MEKS at 50 μg/ml significantly increased the sub-G1 DNA contents of HSC4 cells to 84.8%, versus untreated cells. However, the activation of apoptosis-associated proteins such as cleaved caspase 3, cleaved caspase 8, cleaved caspase 9 and cleaved Poly (ADP-ribose) polymerase (PARP) did not detect. The level of Bax protein markedly increased in MEKS-treated HSC4 cells. In addition, the cell viability of the DPQ pre-treated HSC4 cells with MEKS treatment was significantly greater than that of MEKS treated-cells. These results suggest that MEKS inhibits cell proliferation and induces necroptosis in oral cancer cells and that MEKS may have potential chemotherapeutic value for the treatment of human oral cancer.

우리나라 치매 관련기관 종사자의 치매전문교육 요구와 발전 방향

정수아(Jung, Sua),송준아(Song, Jun-Ah),천홍진(Cheon, Hongjin),김지연(Kim, Jiyeon) 한국노인간호학회 2021 노인간호학회지 Vol.23 No.2

Purpose: This study aimed to explore dementia-specialized education and the training needs of employees from various dementia-related institutions in South Korea and propose directions for future development of the standard curriculum. Methods: Qualitative data were generated from four round-table meetings with 44 participants recruited from the metropolitan centers for dementia (N=12), regional dementia-relief centers (N=15), long-term care settings (N=7), and public long-term care hospitals (N=10). Each meeting was held for about 120 minutes, and participants discussed the knowledge, skills, and attitudes required for their job, satisfactory and non-satisfactory experiences of education programs they had participated in, and what should improve. All contents discussed in each meeting were recorded and transcribed verbatim. Data were analyzed using a conventional content-analysis method. Results: Eight categories and 19 subcategories emerged under the three themes of (a) educational contents recognized as necessary, (b) advantages and disadvantages of completed dementia education, and (c) directions for improving educational programs for employees of dementia-related institutions. Conclusion: Dementia-specialized education and training should be standardized and structured systematically and differently depending on the job characteristics, type, and required level of expertise. Communication with and attitudes toward patients with dementia is re-emphasized as a common content regardless of occupation and institution; thus, sufficient training time should be secured. Qualified instructors and various platforms are also necessary to effectively deliver quality education.