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      • GG-38 : Minimal invasive surgery (LESS) for huge cystic adnexal tumors in whole abdomen

        ( In Young Choi ),( Ji Hye Lee ),( Mi Hyun Park ),( Ji Kwoun Park ),( Jeong Kyu Shin1 ),( Won Jun Choi1 ),( Soon Ae Lee ),( Jong Hak Lee ),( Won Young Paik ) 대한산부인과학회 2014 대한산부인과학회 학술대회 Vol.100 No.-

        Laparoendoscopic single-site surgery (LESS) is helpful if not an evidence of suspicious malignancy in huge adnexa tumors. This approach might be reasonable alternative to conventional laparoscopic surgery. We report two cases with LESS for huge cystic adnexal tumors in whole abdomen. A 58 years old multigravida woman in menopause underwent removal of a huge cystic adnexal mass that occupied her entire abdomen by LESS.(ca.5200ml aspiration) A 15 years old single nulligravida woman had a huge cystic adnexal tumor in whole abdomen reaching to the level of the xyphoid process. A needle through the transumbilical single port was inserted directly under the mass. Subsequently, 8000 ml of cystic fluid was aspirated without spillage.

      • KCI등재

        스마트 미디어 환경의 시각 인터페이스 디자인에 관한 연구

        최진원(Jin Won Choi),박정기(Jeong Kee Park) 한국디자인문화학회 2013 한국디자인문화학회지 Vol.19 No.3

        최근 웹뿐만 아니라 모바일 전반을 아우르며 디지털 디바이스의 사용자 환경(UI :User Interface) 디자인 패러다임이 새롭게 변화하고 있다. 이러한 변화 가운데 디바이스가 다양해지고 콘텐츠들이 많아지면서 사용자들은 타 기기에서도 웹 서비스를 일관성 있게 제공받기를 원하게 되었다. 이에 본 연구에서는 스마트 미디어 환경에 대해 이해하고, 웹사이트 UI디자인 동향을 수집하여 특징을 알아보고, 그에 따라 분류된 레이아웃, 스크롤, 해상도, 그래픽요소, 기술 요소를 기준으로 브랜드, 프로모션, 쇼핑몰, 3가지 유형의 사례 분석을 진행하였다. 그 결과 레이아웃은 콘텐츠가 단순하고 비주얼이 강화된 일반 그리드, 브로슈어 레이아웃과 스마트기기에 적합한 블록 레이아웃의 형태가 나타났다. 스크롤은 전반적으로 태블릿, 폰에 좀 더 적합한 싱글 페이지 구조의 세로 스크롤 사이트가 늘어나고 있음을 알수 있었다. 해상도 반응의 경우 다양한 해상도에 대응하는 반응형 웹사이트가 늘어나고 있고, 그래픽 요소의 경우 직관적이고 신뢰할 수 있는 사진 이미지의 사용이 많았다. 기술적 요소는 스마트 기기에 적합한 html5, jQuery의 적용이 많았고, 세로 스크롤 방식을 통해 마우스 휠이 아닌 넘김 방식으로 스토리에 맞는 모션이 혼합되어 차별화된 경험을 제공했다. 이러한 결과로 도출된 동향을 통해 추후 웹사이트 제작 시기초자료로 활용할 수 있으리라 기대한다. Recently, with the web as well as mobile digital devices, the user experience (UI: User Interface) is a new design paradigm is changing. Among these changes, the device As more users are diverse and content to other devices, in addition to the PC consistently provide Web services were to be won. In this research, a smart media environment for the understanding and design trends by collecting website UI features to learn, and accordingly classified layout, scroll, resolution, design elements, technical elements, based on brand, promotion, shopping malls, three type of case analysis was conducted. As a result, the content, the layout is simple and regular grid with enhanced visuals, brochure layout and is suitable for smart devices in the form of a block layout appeared. Scroll structure as a whole tablet, phones, a more suitable structure of a single-page vertical scroll was found that increasing the site. Resolution corresponding to different resolutions reaction responsive Web sites is growing, graphic elements, the intuitive and reliable use of photographic images respectively. Technology components suitable for the smart devices html5, jQuery application of the common vertical scrolling mouse wheel over the story in a way that meets a non-feed is a mixture of motion were differentiated experience. As a result, the derived trends as a basis for making future web site can use to expect that.

      • SCIESCOPUSKCI등재

        Cordyceps militaris alleviates non-alcoholic fatty liver disease in ob/ob mice

        Ha-Neul Choi,Yang-Hee Jang,Min-Joo Kim,Min Jeong Seo,Byoung Won Kang,Yong Kee Jeong3,,Jung-In Kim 대한지역사회영양학회 2014 Nutrition Research and Practice Vol.8 No.2

        BACKGROUND/OBJECTIVES: Non-alcoholic fatty liver disease (NAFLD) is becoming an important public health problem as metabolic syndrome and type 2 diabetes have become epidemic. In this study we investigated the protective effect of Cordyceps militaris (C. militaris) against NAFLD in an obese mouse model. MATERIALS/METHODS: Four-week-old male ob/ob mice were fed an AIN-93G diet or a diet containing 1% C. militaris water extract for 10 weeks after 1 week of adaptation. Serum glucose, insulin, free fatty acid (FFA), alanine transaminase (ALT), and proinflammatory cytokines were measured. Hepatic levels of lipids, glutathione (GSH), and lipid peroxide were determined. RESULTS: Consumption of C. militaris significantly decreased serum glucose, as well as homeostasis model assessment for insulin resistance (HOMA-IR), in ob/ob mice. In addition to lowering serum FFA levels, C. militaris also significantly decreased hepatic total lipids and triglyceride contents. Serum ALT activities and tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) levels were reduced by C. militaris. Consumption of C. militaris increased hepatic GSH and reduced lipid peroxide levels. CONCLUSIONS: These results indicate that C. militaris can exert protective effects against development of NAFLD, partly by reducing inflammatory cytokines and improving hepatic antioxidant status in ob/ob mice.

      • 난지형 조숙종 마늘 신품종 ‘올캐’ 특성

        최학순(Hak Soon Choi1),채원병(Won-Byoung Chae),곽용범(Yong-Bum Kwack),정명일(Myeong-Il Jeong) 한국원예학회 2008 한국원예학회 학술발표요지 Vol.2008 No.12

        원예연구소 남해출장소에서는 원예적 특성이 우수한 유전자원을 도입 선발하여 ‘올캐’로 명명하였다. 특성평가를 2000년부터 3년간 실시하였으며 2003년부터 3년간 지역적응시험을 실시한 결과 그 특성이 우수하여 품종등록 하였다. 도입 육성한 ‘올캐’ 마늘은 난지형 조숙종 마늘로 생태형으로는 난지형이며 추대형은 완전 추대종이다. 인경의 모양은 아래가 평편한 구형이며 구색과 인편색은 약간 자색이 돈다. 인편의 배열은 동심형(concentric)으로 ‘남도’ 마늘과 같다. 초형은 직립이며 초장, 엽초경 및 잎의 수는 대비종인 ‘남도’ 마늘에 비해서 약간 작거나 적으며 잎의 색깔은 ‘남도’ 마늘에 비해서 약간 연한 녹색이다. 평균구중은 42.2g으로 ‘남도’ 마늘 40.5g 보다 약간 무거우며 인경의 모양은 대비종인 ‘남도’ 마늘과 비슷하다. ‘올캐’ 마늘의 추대기는 3월 하순으로 ‘남도’ 마늘보다 15~20일 정도 빠르며 수확기도 일주일 이상 빠르다. Namhae Sub-station of National Horticultural Research Institute has collected 240 different garlic germplasms since 1999 and has used germplasms of superior quality. Among them, ‘Namhae 57328’ is a precocious variety with superior characteristics of growth and bulb, and was named ‘Allkae’ garlic (Allium sativum) in 2006. The garlic was registered after 3 consecutive years’ assessment of the variety trait starting from 2000 and a 3 consecutive years’ adaptability test from 2003. The ecotype of ‘Allkae’ garlic is southern one and bolting one is complete bolting type. The bottom of a bulb is flat and the colors of a bulb and a clove are light purple, and the arrangement of cloves is concentric as in ‘Namdo’ garlic. The plant type is erect one and its height is slightly smaller than ‘Namdo’ garlic’ one but it’s bolting in mid March which is about 20 days ahead of ‘Namdo’ garlic. Average bulb weight is 42.2 g which is slightly heavier than ‘Namdo’ garlic (40.5 g). The shape of the bulb is similar with ‘Namdo’ garlic.

      • KCI등재

        Long-term outcomes of single-port laparoscopic myomectomy using a modified suture technique

        ( Mina Kang ),( Jihye Kim ),( Tae-joong Kim ),( Jeong-won Lee ),( Byoung-gie Kim ),( Duk-soo Bae ),( Chel Hun Choi ) 대한산부인과학회 2020 Obstetrics & Gynecology Science Vol.63 No.2

        Objective To evaluate the long-term outcomes, including the pregnancy outcome and recurrence rate after single-port laparoscopic myomectomy (LM) using a modified suture technique with a Hem-o-lok clip (Choi’s LM) and conventional 4-port LM. Methods A retrospective study of patients who underwent Choi’s LM (n=55) and 4-port LM (n=102) in a single institutional hospital was conducted. Patients with <3 symptomatic myomas sized <10 cm each and operated on by a single surgeon were included. Recurrence was confirmed when a myoma measuring ≥3 cm was detected. Results The patients in both groups had similar demographic characteristics. Single (76.4% vs. 62.7%) and intramural (52.7% vs. 56.9%) tumors were commonly detected in both groups in the mean diameter (6.8±1.5 cm vs. 7.0±1.6 cm; P=0.40). In Choi’s LM, 16 patients (29.1%) needed an additional port; those who were nulliparous and/or had a large leiomyoma more frequently required an additional port (P=0.023 and 0.04, respectively). During a median follow-up period of 69 months, 17 patients (7.1% vs. 14.6%) had recurrence. The size of dominant myomas at recurrence was significantly smaller in patients who underwent Choi’s LM (3.4±0.7 cm vs. 5.7±2.4 cm; P=0.004). All 13 patients in both groups who successfully conceived had a full-term delivery. No major complications occurred during pregnancy. Conclusion Although an additional port was frequently used, the long-term outcomes of patients who experienced recurrence and pregnancy after Choi’s LM were acceptable. Considering its usability, Choi’s LM is feasible for the treatment of uterine leiomyoma.

      • KCI등재

        기상조절(인공강우와 안개저감)의 경제적 가치 추정 연구

        이철규(Chulkyu Lee),장기호(Ki-Ho Chang),차주완(Joo-Wan Cha),정재원(Jae-Won Jung),정진임(Jin-Yim Jeong),양하영(Ha-Young Yang),서성규(Sung-Kyu Seo),배진영(Jin-Young Bae),강선영(Sun-Young Kang),최영진(Young-Jean Choi),조하만(Ha-man Cho) 한국기상학회 2010 대기 Vol.20 No.2

        We estimate the economic benefit of weather modification (precipitation enhancement and fog dissipation) by assuming its operation for the considered regions. Based on the statistical data, the economic benefit of the virtually operational precipitation enhancement experiments for the Andong and Imha basins, where the natural precipitation is relatively lack in South Korea, is calculated 348 for the water resources, 22,458 for forest fire prevention, and 28,458 million won/year for the drought relief. The benefit of the fog dissipation operation for the Incheon International Airport is estimated 7,365 million won/year for the flight delay due to fog. The calculated ratio of benefit to cost for precipitation enhancement operation for the basins is 14.07, which is comparable to that conducted in other countries.

      • KCI등재

        Effects of Fenofibrate on Adipogenesis in Female C57BL/6J Mice

        Jeong, Sunhyo,Choi, Won Chang,Yoon, Michung 대한의생명과학회 2005 Biomedical Science Letters Vol.11 No.1

        Fibrates are a class of hypolipidemic agents whose effects are mediated by activation of a specific transcription factor called the peroxisome proliferator-activated receptor α (PPARα). PPARα regulates the pathways of lipid catabolism such as fatty acid oxidation and the triglyceride metabolism, resulting in the treatment of hyperlipidemia. The decreased levels of plasma triglycerides by fibrates are responsible for hypertrophy and hyperpalsia of adipose cells. To determine whether fenofibrate regulates adipogenesis in female C57BL/6J mice, we measured the effects of fenofibrate on not only body weight, adipose tissue mass and serum triglycerides, but also the histology of adipose tissue and the expression of adipocyte marker genes. Fenofibrate did not inhibit high fat diet-induced increases in body weight, adipose tissue mass and serum triglycerides. Furthermore, fenofibrate did not cause the changes in the size and number of adipocytes and the expression of adipocyte-specific genes such as leptin and TNFα. Therefore, this study demonstrates that fenofibrate does not affect adipogenesis in female mice.

      • An injectable and physical levan-based hydrogel as a dermal filler for soft tissue augmentation

        Choi, Won Il,Hwang, Youngmin,Sahu, Abhishek,Min, Kiyoon,Sung, Daekyung,Tae, Giyoong,Chang, Jeong Ho The Royal Society of Chemistry 2018 Biomaterials Science Vol.6 No.10

        <P>The use of injectable materials as a biofiller for soft tissue augmentation has been increasing worldwide. Levan is a biocompatible and inexpensive polysaccharide with great potential in biomaterial applications, but it has not been extensively studied. In this study, we evaluated the potential of levan as a new material for dermal fillers and prepared an injectable and physical levan-based hydrogel by combining levan with Pluronic and carboxymethyl cellulose (CMC). A sol state was prepared by mixing the polymers in a specific ratio at 4 °C for 2 days and the hydrogel was formed by increasing the temperature to 37 °C. The elastic modulus of the levan hydrogel was higher than that of a hyaluronic acid (HA)-based hydrogel. The SEM images of the levan hydrogel showed an interconnected porous structure, similar to the HA hydrogel. Levan showed non-cytotoxicity, enhanced cell proliferation, and higher amount of collagen synthesis in human dermal fibroblast cells compared to HA. The injected levan hydrogel was biocompatible and stable over 2 weeks <I>in vivo</I>, longer than the Pluronic F127 hydrogel or HA hydrogel. Also, the levan hydrogel showed a higher amount of collagen production than the HA hydrogel <I>in vivo</I>. More importantly, the levan hydrogel showed enhanced anti-wrinkle efficacy compared to the HA hydrogel in a wrinkle model mouse. Thus, the levan hydrogel with injectability, biocompatibility, and an anti-wrinkle effect has high potential as an alternative to existing commercial dermal fillers.</P>

      • Changes in Gait Characteristics due to Outsole Structure of Shoe

        Choi, Jin Seung,Kang, Dong Won,Seo, Jeong Woo,Kim, Ju Young,Yang, Seung Tae,Kim, Dae Hyeok,Tack, Gye Rae Trans Tech Publications, Ltd. 2015 Applied Mechanics and Materials Vol.775 No.-

        <P>The purpose of this study was to evaluate changes in kinematic and kinetic gait characteristics due to outsole structure of the shoe. In this experiment, cushioning shoe having cushion for heel (BOSS Corps., Korea) which is designed as a lever, MBT having an unstable rounded shoe (Masai Barefoot Technology, MBT, Swiss) and normal running shoe (Adidas, Germany) were compared. The experiment was performed walking on the straight walkway (10m x 3m) five times with preferred walking speed. 3D motion capture system was used to acquire kinematic and kinetic data using six infrared cameras and two force plates. For comparison among shoes, walking velocity, hip, knee and ankle joint angles (range of motion, trajectory), ground reaction force (loading rate, the decay rate, maximal vertical ground reaction force), and center of mass - center of pressure inclination angle (COM-COP angle) were used. The results showed that there were different effects of types of shoe on lower extremities. Joint angle trajectory of ankle, joint range of motion (ROM) of the hip, and peak force were significantly different among shoe types. MBT provided a decreased impact force. Cushioning shoe provided increased progressive force, decreased loading rate, and decreased COM-COP angle. For further study, it is necessary to analyze additional subjects (i.e., elderly) and long-term effects.</P>

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