쐐기형 5급 와동과 근관와동을 복합레진으로 수복한 상악소구치에 대한 응력 분석 : 3차원 유한요소법적 연구

이선화,김현철,허복,김광훈,손권,박정길 大韓齒科保存學會 2008 Restorative Dentistry & Endodontics Vol.33 No.6

이 연구의 목적은 쐐기형 5급 와동과 근관와동을 복합레진으로 수복한 상악 제2소구치에 대한 응력 분포를 3차원 유한요소법으로 분석하여 평가하기 위한 것이다. 발치된 상악 제2소구치를 이용하여 Micro-CT로 스캔한 후 3D-D0C-TOR로 3차원 유한요소 모형을 제작하였다. 제작된 소구치 모형에 근관 와동을 형성하고 쐐기형 5급 와동과 글래스 아이오노머 기저재의 사용 여부를 구분하여 근관 와동을 혼합형 복합레진으로 충전하였다. 협측 교두 또는 설측 교두에 500 N의 하중을 가하고, ANSYS 8.0 프로그램으로 인장 응력의 분포를 분석하여 평가한 결과 베이스 사용유무에 따른 응력 분포의 차이는 없었다. 협측 교두에 하중이 가해질 때, 하중점과 교합면의 중심구, 구개측 백악법랑경계부에 과도한 인장 응력이 집중되었으며, 5급 와동이 없는 경우보다 5급 와동이 있는 경우에 약간 더 높았다. 설측 교두의 협측 경사면에 하중이 가해질 때, 하중점과 교합면의 중심구, 협측 치경부에 과도한 인장 응력이 집중되었으며, 5급 와동이 있는 경우가 5급 와동이 없는 경우보다 약간 더 낮았다. The purpose of this study was to investigate the distribution of tensile stress of canal obturated maxillary second premolar with access cavity and notch-shaped class Ⅴ cavity restored with composite resin using a 3D finite element analysis. The tested groups were classified as 8 situations by only access cavity or access cavity with notch-shaped class Ⅴ cavity (S or N), loading condition (L1 or L2), and with or without glass ionomer cement base (R1 or R2). A static load of 500 N was applied at buccal and palatal cusps. Notch-shaped cavity and access cavity were filled microhybrid composite resin (Z100) with or without GIC base (Fuji Ⅱ LC). The tensile stresses presented in the buccal cervical area, palatal cervical area and occlusal surface were analyzed using ANSYS. Tensile stress distributions were similar regardless of base. When the load was applied on the buccal cusp, excessive high tensile stress was concentrated around the loading point and along the central groove of occlusal surface. The tensile stress values of the tooth with class Ⅴ cavity were slightly higher than that of the tooth without class Ⅴ cavity. When the load was applied the palatal cusp, excessive" high tensile stress was concentrated around the loading point and along the central groove of occlusal surface. The ten-sile stress values of the tooth without class Ⅴ cavity were slightly higher than that of the tooth with class Ⅴ cavity.

콩 종간교잡에서 주요형질의 유전분석

이정동,권택화,조호영,황영현 慶北大學校農業科學技術硏究所 2002 慶北大農學誌 Vol.20 No.-

재배종과 야생종의 인공교잡 분리세대에서 주요형질들의 변이와 유전력을 조사하여 야생종을 이용한 콩 품종육성의 기초자료를 얻고자 수행한 결과를 요약하면 다음과 같다. 두 인공교배의 F_2 집단에서 100립중을 제외한 나머지 조사 형질들은 초원분리를 보였다. F_1과 F_2의 평균 개화일수는 양친의 중간정도로 정규 분포를 보였다. 백립중의 F_1 평균은 은하콩, 소백나물콩 두 조합 각각6.5, 5.7g으로 소립종 쪽으로 치우친 정규분포를 보였다. F_2의 평균수량은 양친의 중간정도이었다. F_1의 덩굴성은 두 조합 각각 6.4, 6.6이었으며 F_2 평균은 은하콩 조합이 6.0으로 덩굴성 쪽으로 치우쳐 덩굴성이 부분적인 우성으로 보였으나, 소백나물콩 조합에서는 4.6으로 은하콩과는 다른 결과를 보였다. 경장, 개회일수, 개체당 협수, 수량, 도복, 덩굴성 등은 높은 광의의 유전력을 보였으며 100립중은 협의의 유전력이 은하콩 조합에서 52.3%, 소백나물콩 조합에서 65.6%로 평가되어 초기세대에서의 선발이 가능한 것으로 나타났다. This study was conducted to obtain the information of varietal development using wild soybean through investigation of variation and heredity of major agronomic characters in F_2 generation of interspecific cross between Glycine max and G. soja. In segregating populations of two crosses, all characters observed except 100-seed weight showed transgressive segregation. Days to flowering showed normal distribution; mean days to flowering in F_1 and F_2 was approximately mean of parent. Mean of F_1 for 100-seed weight was 6.2g and 5.7g for Eunhakong/KLG10084 and Sobaegnamulkong/KLG10084, respectively, which were somewhat skewed distribution to small seeded parent. Mean of F_2 was about mean of two parents. Degree of vine was 6.4 and 5.7 in F_1 for two crosses but it was 6.0 in F_2 for Eunhakong/KLG10084, which revealed the degree of vine as partial dominance while 4.6 for Sobasgnamulkong/KLG10084, somewhat different results from the previous cross. Broad-sense heritability(h^2B) for plant height, days to flowering, pods per plant, seed yield, and degree of vine was comparatively high and narrow-sense heritability(h^2N) for 100-seed weight which is the most important character in the development of small seed-size sprout soybean was 52.3% and 65.6% for Eunhakong/KLG10084 and Sobaegnamulkong/KLG10084, respectively, which indicated that selection for the character in early generation was possible.

산재지정병원 이용 후 산재요양환자에 대한 만족도 조사

이화평,임형준,주영수,권영준,강희태,김정민,조성식,이태경,윤종완 대한산업의학회 2007 대한직업환경의학회지 Vol.19 No.3

MPEG-21 표준의 구현을 위한 Testbed 구축

손정화,손현식,조영란,권혁민,김만배 강원대학교 정보통신연구소 2003 정보통신논문지 Vol.7 No.-

1990년대 후반부터 다양한 디지털 통신망을 이용하여 멀티미디어 컨텐츠 서비스가 가능하게 되었다. 하지만, 멀티미디어 컨텐츠의 전달 및 이용을 위한 기반 구조들의 독자적 발전 및 다양한 통합적 관리 체계 시스템으로 인해, 멀티미디어 컨텐츠 표현 방식의 호환성 문제, 혼재하는 네트워크 전달 방식과 단말 방식의 호환성 문제 등의 잠재적인 문제점이 발생한다. 이런 문제의 대안으로 현재 존재하는 기술 및 기반 구조들 사이의 연동을 통한 큰 프레임워크인 MPEG-21이 진행 중이다. 본 논문에서는 현재 표준화 작업이 진행 중인 MPEG-21을 기반으로 하는 Testbed를 제안한다. Testbed는 server, client, DIA(Digital Item Adaptation)의 세 모듈로 구성된다. Server의 역할은 멀티미디어 컨텐츠를 Digital Item(DI)으로 생성하고, client가 DI를 요구할 경우 DIA 모듈을 통해서 변환된 DI를 client에게 제공한다. DIA 모듈은 server에서 동작되며 client로부터 요청된 DI를 분석하고 client로부터 전송된 환경 정보를 이용하여 client 환경에 적합하게 변환된(adapted) DI를 생성하는 것이 주 기능이다. Client는 server에 저장되어 있는 DI를 선택하고 user preference, terminal capability 등의 필요한 정보를 server로 전송한다. Testbed에서는 스포츠 경기의 동영상, 정지 영상, 경기 내용, 역사를 기록한 파일 등의 DI를 이용한다. 표현 언어는 XML이며, HTTP 기반의 Web 환경에서 구동되도록 설계된다.

낭종 적출후 악골 결손부 치유에 관한 동종골 이식 효과에 관한 연구

이동근,박화규,권경환,강문정,신기영,민승기,성헌모 大韓顎顔面成形再建外科學會 1999 Maxillofacial Plastic Reconstructive Surgery Vol.21 No.4

This study was aimed to suggest to better treatment method of jaw cyst that the maximum diameter was wider than 3cm, using different treatment and clinical and radiographic result. We divided the 60 patients into three groups, group A(20 patients) were treated with cyst enucleation and Decalcified Freeze-Dried Allogeneic Bone(DFDB) graft, group B(20 patients) were treated with cyst enucleation and autogenous bone graft, group C(20 patients) were treated with only cyst enucleation. Each group was evaluated with panramic radiograph and clinical sign & symptom at pre-op and post-op(immediate, 6, 12, 24, 36 month). Bone density was evaluated with disital densitometer. The result was as follows : 1. Post-Op infection was higher in group C(4 pts.) than in group A(1 pt.) and B(1 pt.) 2. Post-Op gingival recession was higher in group C(3 Pts.) than in group A(1 pt.) and B(1 pt.) 3. Anatomic distortion was higher in group C(3 Pt.) than in group A(1 Pt.), and B(1 pt.) 4. reoperation was done in two patients who were in group C 5. There were donor site morbidity in two patients 6. there was no significant difference between group A and B in their bony density in their follow up period(p>0.05). 7. There were significant differences between group A, B and group C in their bony density until post-op 24 months but a little differences at post-op 36 months(P<0.01)

한국 재래 나물콩 품종 및 계통의 콩나물 특성

황영현,이정동,조호영,권택화,정연신 慶北大學校農業科學技術硏究所 2002 慶北大農學誌 Vol.20 No.-

우수한 특성을 가진 나물콩 품종 육성을 위하여 국내 재래 나물콩 계통의 콩나물 특성을 분석한 결과는 다음과 같다. 1. 공시된 301품종 및 계통의 콩나물 전체길이의 범위는 9.5∼23.0cm, 하배축 길이는 5.9∼15.1cm, 뿌리 길이는 3.2∼9.2cm로 다양한 변이를 보였고, 수율에서도 121∼695%로 다양하게 분포하고 있다. 2. 공시된 301품종 및 계통의 종피색에 따른 콩나물 수율은 혼색종피종에서 409%로 가장 높게 나타났고, 백립중에 따른 콩나물 수율은 소립종일수록 높은 경향이었으며, 잔뿌리수는 흑색종피종과 갈색 종피종에서 현저히 적었다. 3. 콩나물 길이와 전체길이에 대한 뿌리길이의 비율, 수율을 기준으로 한 공시품종 및 계통들의 분포에서 장려품종보다 우수한 특성을 가지는 다수의 재래계통이 분포하고 있었다. 4. 콩나물 하배축의 색도는 백색도(L값)에서 장려품종이 재래계통에 비해 백색에 더 가까웠고, 적색도(a값)와 황색도(c값)는 장려품종보다 재래계통에서 높은 경향이었다. To develop good soybean varieties for sprouts. 285 indigenous lines and 16 recommending varieties were evaluated by the sprout and agronomic characteristics. The range of whole length, hypocotyl length, root length, and yield rate of sprouts was 9.5~23.0cm, 5.9~15.1cm, 3.2~9.2cm, and 121~695%, respectively. Yield rate of sprouts was the highest, 409%, in the lines of mixed seed coat color. At the same time, it was reversely proportional to seed weight : the smaller the seed weight, the higher the yield rate as in all other reports. The number of roots was significantly fewer in the lines of the black and the green seed coat color than others. Based on whole length, rate of root length, and yield rate of sprouts, many indigenous lines were evaluated much better than recommending varieties. In the hypocotyl color of sprouts, the brightness was higher in improved variety than indigenous lines but vice versa in redness and yellowness in general.

여호와의 증인 환자에서 산과적 출혈 후 무수혈 치료 2예

김재령,여소진,이해혁,김정식,김태희,남계현,이권해,이임순,박진화,황경호 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Jehovah's Witness comprise a unique obstetric population. Their refusal of blood stems from an interpretation of a literal translation of the Bible, and it is this belief that puts them at an increased risk of morbidity and mortality if hemorrhage occurs. We report two cases of a Jehovah's Witness who bled massively due to obstetric hemorrhage, refused blood transfusion and had profound anemia. The patients were treated with recombinant human erythropoietin, parenteral iron and oxygen. And they were treated on an intensive care unit with intermittent positive pressure ventilation. We reviewed with literature considering the therapy for acutely anemic patients who refuse transfusion to decrease the duration of the most severe anemia.

Analysis of the Shading Effectiveness of Photo-selective White Wash Agents Applied on Even-span Glasshouse in Summer Season

Jeong Hwa Kang,Doo Hyun Kwon,Seung Ho Shin,Hye Min Kim,Hyun Woo Jeong,Min Ji No,Ji Young Seo,Yeo Hyun Yoon,Seung Jae Hwang 한국원예학회 2012 한국원예학회 학술발표요지 Vol.2012 No.10

Enhanced angiogenesis mediated by vascular endothelial growth factor plasmid-loaded thermo-responsive amphiphilic polymer in a rat myocardial infarction model

Kwon, Jin Sook,Park, In Kyu,Cho, Ae Shin,Shin, Sun Mi,Hong, Moon Hwa,Jeong, Seo Yeon,Kim, Yong Sook,Min, Jung-Joon,Jeong, Myung Ho,Kim, Won Jong,Jo, Seongbong,Pun, Suzie H.,Cho, Jeong Gwan,Park, Jong Elsevier 2009 Journal of controlled release Vol.138 No.2

<P><B>Abstract</B></P><P>Thermo-responsive hydrogel-mediated gene transfer may be preferred for the muscle, because the release of DNA into the surrounding tissue can be controlled by the 3-dimensional structure of the hydrogel. Such a system for the controlled release of a therapeutic gene may extend the duration of gene expression. Here, a thermo-responsive, biodegradable polymeric hydrogel was synthesized for local gene transfer in the heart. Initially, the luciferase gene was delivered into mouse heart. The intensity of gene expression assessed by optical imaging was closely correlated with the expressed protein concentration measured by luciferase assay in homogenized heart. Polymeric hydrogel-based gene transfer enhanced gene expression up to 4 fold, compared with naked plasmid, and displayed 2 bi-modal expression profiles with peaks at 2?days and around 25?days after local injection. Histological analyses showed that gene expression was initially highest in the myocardium, whereas lower and longer expression was seen mainly in fibrotic or inflammatory cells that infiltrated the injury site during injection. Next, a rat myocardial infarction model was made for 1?week, and human vascular endothelial growth factor (hVEGF) plasmid was injected into the infarct area with an amphiphilic thermo-responsive polymer. Enhanced and sustained hVEGF expression in the infarct region mediated by amphiphilic thermo-responsive polymer increased capillary density and larger vessel formation, thus enabling effective angiogenesis.</P> <P><B>Graphical abstract</B></P><P><ce:figure></ce:figure></P>

Origin of Restenosis after Drug-Eluting Stent Implantation in Hyperglycemia is Inflammatory Cells and Thrombus

Kwon, Jin Sook,Kim, Yong Sook,Cho, Ae Shin,Kim, Jeong Sook,Jeong, Seo Yeon,Hong, Moon Hwa,Jeong, Myung Ho,Ahn, Youngkeun Japan Atherosclerosis Society 2011 Journal of atherosclerosis and thrombosis Vol.18 No.7

<P>Aims: The cellular and molecular mechanisms and safety after drug-eluting stent (DES) implantation in diabetic patients are still poorly understood; therefore, in this study, we evaluated the pathologic responses of the sirolimus-eluting stent (SES) or paclitaxel-eluting stent (PES) in a type I diabetes mellitus (DM) rat model.Methods: The type I DM rat model was manipulated by intra-peritoneal streptozotocin injection. Two weeks later, DES was implanted in the aorta of rats with hyperglycemia or not as a control. Four weeks after DES implantation, the stented aorta was isolated and histomorphometric analysis was performed.Results: On histomorphometric analysis, increased thrombus, inflammatory cell infiltration, and neointimal hyperplasia (NIH) without change of the smooth muscle cell number after DES implantation were observed in DM rats compared with non-DM (NDM) rats. Furthermore, delayed coverage of mature endothelial cells defined as a von Willebrand factor expression and increased immature endothelial cells as a c-kit expression after DES implantation were observed in DM rats compared with NDM rats. Increased fibrin deposition and decreased hyaluronic acid accumulation at NIH after DES implantation were also observed in DM rats compared with NDM rats.Conclusions: In conclusion, the main mechanism of restenosis after DES implantation under hyperglycemic conditions was initial thrombus with changes of the extracellular matrix rather than SMC proliferation. These results provided a therapeutic clue for the selection of DES and application of combination therapy using anti-thrombotic and anti-inflammatory drugs in diabetic patients.</P>