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      • 건강한 성인에서 발병한 칸디다와 연관된 위궤양 1례

        박지훈,이상혁,김희,이재호,박성재,지삼룡,양성연,박은택,이연재,설상영,정정명,강미선 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

        Fungus such as Candida albicans is a normal flora that is frequently found in the oral cavity, gastrointestinal tract, genitourinary tract, vaginal mucosa in a normal person. However, candida can cause opportunistic infection in an immune compromised host. Candidiasis has broad spectrum of disease from mucocutaneous infection to invasive or disseminated infection. But, it is rarely reported that candida is associaed with gastrointestinal tract disease in a healthy adult. The case of gastric ulcer associated with candida particularly in a health adult is reported with relevant literature.

      • 바터 팽대부에 생긴 유암종 1예

        강명주,지삼룡,박석주,이재익,조영완,김준영,박성재,박은택,이연재,이상혁,설상영,배상균 인제대학교 2006 仁濟醫學 Vol.27 No.-

        Carcinoid tumors have been reported in a wide range of organs but most commonly involve the lungs, bronchi and gastrointestinal tract. Within the gastrointestinal tract, appendix is the most common location for carcinoid, followed by the distal small intestine, the rectum, and the stomach. Among these, primary involvement of the ampulla of Vater is extremely rare. We report a case of carcinoid tumor of ampulla of Vater. A 62-year-old man presented with epigastric soreness. Gastroduodenal endoscopy showed hyperemic bulging mass on ampulla of Vater and diagnosed as carcinoid tumor by histologic finding, with immunohistochemical study. In ^(111)In-octreoscan, tumor had regional lymph node metastasis, but no evidence of distant metastasis. Pancreatoduodenectomy with lymph node dissection was performed.

      • 간세포암의 고주파 열치료 후 천자침 경로를 통한 전이 1례

        조영완,박석주,진한영,김준영,이재익,강명주,박정하,윤정희,박성재,지삼룡,이연재,이상혁,설상영 인제대학교 2006 仁濟醫學 Vol.27 No.-

        Radiofrequency ablation(RFA), as a form of minimally invasive therapy for hepatocellular carcinoma, has become an important treatment modality. Because of limitation of surgery, RFA has become standard therapy for hepatocellular carcinoma in some situations. But there are some complications of RFA such as bleeding, infection, hematoma, adjacent organ thermal damage including intestinal perforation, needle track seeding, and so on. There are few reports in the literature that systematically evaluate the incidence of needle tract seeding and its associated risk factors. And only 2 cases of needle tract seeding of hepatocellular carcinoma after RFA were reported in Korea. We report a case of needle tract seeding of hepatocellular carcinoma after RFA.

      • KCI등재

        열공형과 비열공형 피질하 혈관성 치매에서 위험인자의 차이에 관한 비교 연구

        배희준,정지향,유경호,나덕렬,김상윤,최경규,양동원,손의주,이상도,김재우,박경원,김응규,이재홍,박미영,한일우,함동석,최문성,하충건,최성혜,이애영,이병철,한설희 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.2

        Backgrounds and Objectives: Vascular dementia is a group of dementing disoders arising from various stroke syndrome. Among these. subcortical ischemic vascular dementia (SIVD) is regarded as a relatively distinct clinical entity. However, MRI patterns of SIVD are not homogenous. In some patients, lacunes are dominant, and in others, subcortical white matter changes are. This study was designed to compare risk factor profiles between SIVD with and without multiple lacunes. Methods: We divided 47 subjects (22 males, mean age. 68 years) recruited from VADAPET (Multicenter Trial For Evaluation Of The Changes In the PET Images Of Subcortical Vascular Dementia Patient) study into two groups one with more than 5 lacunes in deep gray matter (lacune group) and the other with 5 or less(non-lacune group) Clinical characteristics and laboratory findings of two groups were compared. Results: Nineteen of 47 patients (40%) belonged to the lacune group. The lacune and non-lacune groups d d not differ in the following variables: age, hypertension, diabetes mellitus, hyperlipidemia heart disease, history of stroke or TIA, history of trauma or major surgery, family history of hypertension stroke, or dementia, age at diagnosis of dementia, body mass index, white blood cell count, ESR, CRP, fibrinogen, hemoglobin A1C, total cholesterol. LDL cholesterol creatinine, proteinuria, glucosuria, and microhematuria. However, male sex, smoking alcohol. hemoglobin, and HDL cholesterol were possibly associated more with lacune group SIVD than with non-lacune group (p<0 1) Multivariate analyses revealed that smoking, hemoglobin, and HDL cholesterol were independent predictors of SIVD with multiple lacunes Conclusion: Our study suggests that SIVD with multiple lacunes may be significantly different in smoking habits hemoglobin, and HDL cholesterol from SIVD without multiple lacunes.

      • KCI등재

        레이저 형광법을 이용한 인접면 우식증의 진단

        설재헌,오유향,이난영,이상호 大韓小兒齒科學會 2004 大韓小兒齒科學會誌 Vol.31 No.2

        레이저 형광법을 이용하여 초기 인접면 우식증을 탐지할 수 있는지의 여부와 그 탐지 감도를 평가하여 인접면 우식증의 진단에 활용 가능한지의 여부를 규명하기 위하여 사람의 치아를 사용하여 다양한 깊이의 인공우식병소를 유발시키고 이를 가시광선 투과법에 의한 사진, 교익 방사선사진 촬영, 레이저 형광법, 광활성 염료를 이용한 레이저 형광법 등으로 관찰하여 검사법 간의 일치도, 상관관계, 병소 깊이에 따른 광밀도 등을 분석하여 다음과 같은 결과를 얻었다. 1. 탈회시간과 각 검사법들과 일치도 검사에서 사진의 경우 tau-c 값이 0.08로 탈회시간에 따른 사진의 검사 수치가 일치하지 않았으나 교익 방사선사진, 레이저 형광법, 광활성 염료를 이용한 레이저 형광법의 tau-c 값은 각각 0.60, 0.48, 0.64로 일치하는 것으로 나타났다. 2. 탈회시간에 따른 병소깊이와 각 검사법 간의 상관관계는 광활성 염료를 이용한 레이저 형광법(r=0.51), 레이저 형광법(r=0.43), 교익 방사선사진(r=0.35), 사진(r=0.33) 순으로 높았으며 광활성 염료를 이용한 레이저 형광법과 레이저 형광법은 탈회 시간과 상관관계가 있었다(P<0.05). 3. 교익 방사선사진을 기준 검사법으로 한 레이저 형광법과 광활성 염료를 이용한 레이저 형광법의 진단학적 민감도는 각각 67%, 100%였으며 특이도는 57%, 11%로 민감도에 비해 상대적으로 낮게 나타났다. 4. 병소의 깊이에 따른 병소 표면에서의 건전 치질과 우식 치질 사이의 광밀도의 차이(DFR)는 광활성 염료를 이용한 레이저 형광법이 레이저 형광법에 비해 크게 나타났으며(P<O.05) 병소 깊이의 변화에 따른 광밀도 변화는 레이저 형광법의 경우 유의한 변화를 보이는데 반해 광활성 염료를 이용한 레이저 형광법에서는 변화를 보이지 않았다. 이상의 결과를 종합하면, 초기 인접면 우식증의 진단에 있어 레이저 형광법과 광활성 염료를 이용한 레이저 형광법을 교익 방사선사진에 뒤지지 않은 진단능을 가지고 있으나 우식 병소의 정성적인 분석뿐 아니라 정량적 분석이 가능한지의 여부는 향후 더 많은 연구가 필요하리라 사료된다. Artificial carious lesions in various depths were observed with visual examination using light transillumination, bite-wing radiography, laser fluorescence, and dye-enhanced laser fluorescence to determine the reproducibility, correlation of each diagnostic method, diagnostic sensitivity and diagnostic specificity. And optical densities according to demineralized times were measured whether laser fluorescence could be used as a quantitative diagnostic method. The following results were obtained whether laser fluorescence could be used for diagnosis of initial proximal caries. 1. Tau-c values of visual examination was 0.08 which showed lowest reproducibility, and those of bite-wing radiography, laser fluorescence, dye-enhanced laser fluorescence were 0.60, 0.48, and 0.64. respectively which showed relatively high reproducibility. 2. The correlation between demineralization time and each examination was the highest in dye-enhanced laser fluorescence(γ=0.51), followed by laser fluorescence(γ=0.43), bite-wing radiograph(γ=0.35), and visual examination (γ= 0.33). Dye-enhanced laser fluorescence and laser fluorescence showed significant correlation with demineralization time. 3. The sensitivity of laser fluorescence and dye-enhanced laser fluorescence for diagnosing approximal caries based on bite-wing radiography were 67%, 100% and those of specificity were 57%. 11% which showed diagnostic specificity was relatively lower than sensitivity. 4. The difference in optical density(DFR) between sound teeth and carious lesions according to lesion depth was high with dye-enhanced laser fluorescence compared with laser fluorescence. DFR measured with laser fluorescence according to changes in lesion depth was statistically significant but was not statistically significant with dye-enhanced laser fluorescence. Based on these results, laser fluorescence and dye-enhanced laser fluorescence have comparable diagnostic power as bite-wing radiography in early diagnosis of proximal caries.

      • KCI등재

        출생 시 발생한 특발성 치은섬유종증

        이효설,최형준,최병재,손홍규,이제호 大韓小兒齒科學會 2008 大韓小兒齒科學會誌 Vol.35 No.4

        치은섬유종증(Gingival fibromaotsis)은 치은조직의 섬유성 증식을 나타내는 드문 구강질환이다. 원인은 명확히 규명되지 않았으나 상염색체 우성 또는 열성의 유전성이거나 특발성일수 있다. 주로 영구치 맹출 시기에 나타나기 시작하나, 드물게 유치열기나 출생시부터 이환되는 경우도 있다. 치은은 서서히 증식하여 치아의 해부학적 치관부위를 덮거나 구개 변이를 일으켜 혀 운동장애를 야기하거나 입술 폐쇄를 방해하기도 한다. 이 증례의 환아는 14개월 된 여아로 출생 시부터 계속딘 치은증식을 주소로 내원하였다. 특별한 가족력이나 의학적 병력은 없었고, 임상 유전검사 결과 알려진 어떤 증후군으로 진단되지 않았으나, 신체발달이 지연되어 있었다. 펀치 생검을 하였으며, 조직검사명은 치은섬유유종증이었다. 가족력이 없어 특발성 치은섬유종증으로 진단하였다. 환아의 연령 및 전신 상태를 고려해 치은 절제술 등의 외과적 치료는 연기하기로 하였다. Gingival fibromatosis is a rare condition characterized by varying degrees of gingival hyperplasia. Gingival fibromatosis usually occurs as an isolated disorder or can be associated with a variety of other syndromes. It usually appears at the time of eruption of permanent dentition but, can develop at the time of eruption of the primary dentition and rarely at birth. It may deform palatal contour and subsequently restrict the tongue movement, resulting in interference during speech and mastication. In addition, it incapacitates maintenance of normal lip closure. A 14-month-old girl visited the department of pediatric dentistry, Yonsei University Dental Hospital, for the congenital gingival overgrowth. There was no one in the family, who showed similar pattern of gingival growth. The intraoral clinical examination revealed generalized severe enlargement throughout the maxillary and the mandibular arches. Enlarged gingival tissue was pink and had firm consistency. She was referred for chromosomal analysis, which confirmed absence of any known syndrome. Under local anesthesia, "Punch-biopsy" was performed on the labial area, and the specimen was histologically diagnosed as gingival fibromatosis. For she did not have any medical problem nor familiar history, she was diagnosed as having idiopathic gingival fibromatosis. Regarding her age and behavior, close follow-up was decided.

      • 보드 레벨 플립칩의 4점 굽힘 시험 시 파단 특성 연구

        이용성,정종설,이재헌,신기훈,정성균 한국공작기계학회 2008 한국공작기계학회 춘계학술대회논문집 Vol.2008 No.-

        In general, circuit board assemblies experience various mechanical loadings during assembly and in actual use. The repeated cyclic bending can cause electrical failures due to circuit board cracks, solder interconnects cracks, and the component cracks. In this paper, we report on the failure characteristics of board level flip chips under the repeated cyclic bending. We first describe a new 4-point bending tester, which is developed according to JEDEC standard No.. 22B113. The performance of the tester is then estimated through actual experiments . Test results reveal that the cracks first occur on the outer balls around 20,000 cycles and gradually propagate to the inner balls where cracks are found around 70,000 cycles.

      • 水深變化 및 反射率을 考廬한 港內波高分布에 관한 硏究

        이홍식,지환욱,심재설 中央大學校 建設環境硏究所 1997 環境科學硏究 Vol.8 No.-

        A numerical model is presented for the prediction of wave height distribution in a harbor due to the linear wave theory. The method is based upon the solution of a time-dependent analysis including wave refraction, diffraction, and arbitrary reflection coefficient by the finite difference approach. The present numerical model has been validated in several stages. The result obtained from wave shoaling effect has been compared with hydraulic experimental result presented by Ito and Tanimoto. The portion of the diffracted wave heights in a harbor has also been compared with the experimental works proposed by Nisimura et. al.. Good agreement was obtained between the present model and previously obtained results. Therefore it is concluded that the model can be applied to predict the wave height distribution in a harbor with varying depth and arbitrary reflection coefficients. Finally, a numerical example of this application for the Hwa-Sun harbor is shown.

      • KCI등재

        치과주조용 Ag-Pd-Zn-Sn-In 합금의 시효경화 특성

        이재호,김명진,이희경,김형일,설효정 大韓齒科器材學會 2004 대한치과재료학회지 Vol.31 No.1

        Cu가 첨가되어 있지 않고, 대신에 상대적으로 많은 양의 Zn 그리고 소량의 Sn과 In이 첨가된 치과주조용 Ag-Pd-Zn-Sn-In 합금의 시효경화 특성을 경도 시험, X선회절 실험, 주사전자현미경 관찰, 전자탐침 미소분석법으로 조사하여, 다음과 같은 결과를 얻었다. 1. 950℃에서 용체화처리된 시편을 500℃와 550℃에서 등온시효처리하면, 시효 초기에 경도가 완만히 상승하여 최고 경도에 도달하였고 최고 경도를 일정 기간 유지하고 나서 서서히 하강하였다. 2. 용체화처리된 시편은 Pd 원자가 고용된 Ag-rich α1상, Pd3Sn인 α2상, Pd2Zn인 α3상의 3상 공존이었고, 등온시효처리함에 따라 Ag-rich α1상에서 Pd-rich 상으로 추정되는 β상이 석출하였다. 3. 시효 초기의 경화는 Ag-rich 기지에서 Pd-rich 상의 석출로 인한 격자변형에 기인하는 것으로 추정된다. 4. 시효처리 시간을 연장함에 따른 과시효 연화는 입계에 Ag-rich α1상과 Pd-rich β상으로 된 층상조직의 석출과 조대화에 기인하였다. 5. Pd3Sn인 α2상과 Pd2Zn인 α3상은 시효경화에 기여하지 않았다. Age-hardening characteristics of a dental casting Ag-Pd-Zn-Sn-In alloy without copper (52.0 wt% Ag - 39.9 wt% Pd - 4.0 wt% Zn - 2.0 wt% Sn - 2.0 wt% In - 0.1 wt% Ir) was investigated by means of hardness test, X-ray diffraction study, scanning electron microscopic observations and electron probe microanalysis. The specimen solution-treated at 950℃ was three phases of the Ag-rich α1 phase containing Pd element, the α2 phase based on Pd3Sn and the α3 phase based on Pd2Zn, and the Pd-rich β phase was precipitated from the Ag-rich α1 phase by the isothermal ageing,. The initial hardening seemed to be attributed to coherency strains which were formed in the Ag-rich matrix by the precipitation of Pd-rich phase. Overageing with softening was due to the formation and coarsening of the lamella precipitates at grain boundaries, which were composed of the Ag-rich α1 and Pd-rich β phases. The α2 phase based on Pd3Sn and the α3 phase based on Pd2Zn did not contribute to the age-hardening of this alloy.

      • KCI등재

        화학제재를 이용한 우식상아질 제거 효과 및 레진과의 결합강도에 관한 연구

        강덕일,이병채,설재헌 조선대학교 구강생물학연구소 2003 口腔生物學硏究 Vol.27 No.1

        The aim of this study was to evaluate the effect of chemo-mechanical caries removal system(CarisolvTM, Medi Team. Sweden) for resin adhesion to carious primary and Permanent dentin compared with conventional drilling method. The buccal surface of 92 Primary molars and 92 permanet molars were used. Exposed dentins were occurred artificial caries. 32 tooth of primary molars and 32 tooth of permanet molars were prepared to observe treated dentin surface with CarisolvTM and conventional drilling method by SEM. Other tooth were prepared to measure resin-dentin shear bonding strength according to caries removal methods and dentin adhesive system. Two adhesive systems and a composite resin were used: single bonding agent(Scotchbond Multi-Purpose Plus, 3M) and self-etching bonding system(Prompt L-Pop, 3M ESPE), and a composite resin(Z-250, 3M) The results were as follows : 1. The effect of CarisolvTM on primary dentin was stronger than that to permanent dentin, and dentin surface became rougher with treated CarisolvTM than drilling method. 2. Acid-etched dentin surfaces were showed smoothing without smear layer. 3. In specimen applied single bonding system hybrid layer and adhesive layer were 3-4㎛ and 10-15㎛ in thickness, whereas self-etching bonding system hybrid layer were 1-2㎛ 4. The shear bonding strength of group applied single bonding agent was higher than that applied self-etching priming system(P<0.05). 5. The shear bonding strength of group applied CarisolvTM and self-etching priming system were slightly higher than that applied conventional drilling method and self-etching priming system(P>0.05).

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