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      • 담관계 감염증에서 혈액 및 담즙배양 균주의 특성과 항생제 감수성

        송재훈,이철환,김양수,이성구,이근찬,민영일,김명환 대한감염학회 1994 감염 Vol.26 No.1

        During a three-year period, 600 patients were admitted to the Asan Medical Center because of biliary tract diseases. Both aerobic and anaerobic cultures were performed in 313 patients with cholangitis (bile : 253, blood : 113, both : 53). Of these patients, 189 were positive(bile 159. blood 68. both 38). The most common organisms were E. coli, K pneumoniae, and P. aeruginosa in both bile(respectively, 49.7%, 20.8%, 51.5%) and blood cultures(respectively, 45.6%, 26.5%, 22.1%). Antibiotic therapy did not sterilize bile, but selectively increased the proportions of P. aeruginosa. There was no significant difference in biliary bacteriology according to the history of biliary surgery, or the presence of percutaneous biliary drainage or underlying disease. More than 95% of gram-negative organisms isolated was highly susceptible to imipenem and amikacin. P. aeruginosa was resistant to ceftazidime in 63.3% which might be associated with overuse of the drug during the study period. Further studies will be necessary in patients with cholangitis to determine whether newer antibiotics replace previous combination therapy.

      • KCI등재
      • KCI등재
      • SCOPUSSCIEKCI등재

        두개강내로 전이된 Adenoid Cystic Carcinoma 2례 : 증례보고 Report of Two Cases

        송재욱,윤상민,이창훈,장지수,이승훈,조경자,강신광 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.10

        The authors describe two cases of unusual intracranial metastatic adenoid cystic carcinomas. A 42-year-old woman had a right pariental epidural metastatic mass. presumed hematogenous. spread from a primary tumor in the parotid gland. In second case, a 32-year-old man had a intracranial metastatic adenoid cystic carcinoma mimicking calcified psammomatous meningioma on CT scans. We present these unusual cases with a review of relevant literature and a discussion of possible pathogenesis.

      • 해남지역 하천에서의 비점오염원에 관한 연구

        송재준,천지훈,서지양 木浦大學校 沿岸環境硏究所 1999 沿岸環境硏究 Vol.16 No.1

        It is so difficult to know about the course of non-point source that only few people studying. This is the reason why we did not get good result in water-treatment frequently. Point and non-point source study must be balanced. This report have this intention. Summer is rain season in Korea so we have many problem in water quality. Bad quality originated from agricultural field, non-point source, that flow nutrients, agricultural chemicals, weed chemicals and etc. In this report provide the basic data of non-point source study on river of Haenam Area. Three point that we research is near Bok-pyoung, Kil-ho and Eo-seong bridge at 1999. 7. 5 ∼ 7. 12. Resulted: BOD, COD, SS, T-N, NH₃-N, NO₃-N, T-P, PO₄-P, Alkalinity decrease afterraining, dilution, much amount of water quantity made it. Agricultural section that major non-point source effluent high waste concentration at first stage, but dilution made lower at last. so it is needed that non-point source water storage for improve first stage wastewater at the lower part of a river. And continuous study about non-point source outbreak reason by waste effluent quantity data that made water quality and quantity research after division of the land useness near the river is needed, too.

      • KCI등재후보

        소음성 난청 선별검사용 문진표의 유용성

        송재석,최병수,원종욱,노재훈 大韓産業醫學會 2000 대한직업환경의학회지 Vol.12 No.4

        목적 : 소음 특수건강진단시 문진표의 유용성을 알기 위하여 실시되었다. 방법 : 자료로는 전국을 5대 권역으로 나눈 후 연구에 협조적인 산업보건기관을 대상으로 하여, 소음성 난청이 발생한 사업장과 그 부서에 대하여 정상인 근로자의 검진기록과 작업환경측정 기록 및 문진표를 수집하여 분석하였다. 결 과 : 각각의 문진 항목과 청력이상 여부에 대한 분석결과, 귀에서 소리가 난다고 하는 항목과 최근 작은 소리가 잘 안들린다고 하는 만성 특이적 항목만 청력이상 여부와 관계가 있었고, 급성 항목들은 청력 이상 여부와 통계적 연관성이 없었다. 또한 7개의 설문 항목과 연령 및 근무경력만을 이용하여 청력이상을 판정한다고 하였을 때, 실제 건강진단 결과와 비교하게 되면 민감도, 59 %, 특이도, 88 %로 계산 되었으며, 평균 23 %정도가 잘못 분류되었다. 결 론 : 만성적이고 특이적인 항목을 위주로 한 단순하고도 판별력있는 항목의 개발이 필요하며, 이러한 항목들을 전산화하였을 때, 효과적인 소음성 난청의 선별검사 체계를 구축할 수 있을 것이다. Objectives : This study was performed to investigate the effectiveness of the questionnaire. Methods : Workers'health examination records, work environment record, and questionnaires of selected industries as samples were analysed using logistic regression analysis and discrimination analysis Results'Cases of bearing impairment (Dl+C) as dependent variables, and age, work duration and level of environmental noise as independent variables were selected for multiple unconditional logistic regression analysis. Odds ratio was 4.04 in hearing difficulty, 2.78 in tlnnitus and 1.08 in age. In the second analysis Noise induced hearing loss is selected as dependent variable. The OR in hearing difficulty was 3.67(95 % C.1. : 1.61 8.61), and was 1.09(95 % C.1. : 1.05-1.14) in age. Conditionnal multlple logistic regression analysis was performed. In hearing impairment as dependent variable, the OR of age was 1.02(95 % C.1. : 1.00-1.04) and other variables were not significant. However, NIHL as dependent, the OR of hearing difficulty was 4.57(95 % C.1. : 1.43-14.67). According to multiple logistic regression adopting each items of questionnaire as dependent variable, the only item of hearing difficulty showed significant difference with hearing ability. The discrimination analysis was performed with the class variable of hearing impairment, and discrimination variables of age, work duration, and environment noise level. The sensitivity of 59 %, and specificity of 88 %, and average error count of 23 % were obtained. When the numbers of items answered in questionnaire were assumed as the parameter of judgement for noise induced hearing loss (NIHL), the highest sensitivity and specificity were 33.5% and 49.0% in cases of more than two items answered. Conclusions : The development of items that is simple and discriminative mainly consisted of chronic and specific diseases related items is needed. Computerization for newly developed items might be needed to establish effective surveillance system for NIHL in the future.

      • 열처리 및 보상이온의 주입에 의한 α-수정내의 S₁,S₁',S₁˝ 공명중심들의 변화

        송광섭,최재현,최 덕,최옥천,이재훈 명지대학교 자연과학연구소 1995 자연과학논문집 Vol.12 No.-

        수정시편을 300℃, 400℃,500℃,530℃에서 각각 20시간씩 열처리한 후에 X밴드 전자 공명장치를 사용하여 α-수정내의 S?(1).S?',S?'' 세 공명중심들에 대한 열처리 조건에 따른 공명 신호들의 세기의 변화를 상온에서 조사하였다.열처리 효과로 S?'과 S?'' 공명중심들이 일부 S?(1)으로 전환되었다. 480℃에서 수정시편의 c축 방향으로 15ooV/cm의 전기장을 가하여 시편내에서 +1가의 보상이온들을 빼내거나, 500V/cm 와 1000V/cm의 전기장으로 Li+ 이온과 Na+이온을 각각 주입시킨 후에 공명신호들의 세기를 서로 비교하였다.한편 시편내에서 보상이온들을 빼내지 않고 400℃에서 20V/cm 와 50 V/cm의 약한 전기장으로La+이온을 주입시킨 경우와 200V/cm의 전기장으로 Na+이온을 주입시킨후에 공명신호들의 세기가 변화하는 모습을 조사하였다.Li+ 이온이 시편에 주입됨에 따라 세 공명중심들 모두 공명신호들의 세기가 증가하였으며, Na+이온이 주입된 경우에는 공명신호를의 세기가 크게 감소하였다. 열처리 효과와 전기장 처리의 결과로부터 세 공명중심들 모두 Li+이온에 의하여 전하가 보상되는 것으로 판명되었다. After heating a quartz sample for 20 hours at 300℃, 400℃, 500℃, and 530℃, respectively, the changes of resonances signal intensities of the centers S?(1), S?', and S?''in α-quartz according to the conditions of heat treatments were investigated at room temperature by employing an X-band electron spin resonance spectrometer. The centers S?' and S1'' were partly converted into S?(1) by the effect of heat treatments. After extracting positively monovalent ions from quartz samples by applying an electric field of 1500V/cm along the crystal c-axis at 480℃ and after electrodiffusing Li+ ions and Na+ ions into the samples with applied electric fields of 500 and 1000 V/cm, respectively, the intensities of resonance spectra were compared with each other. On the other hand a quartz sample was electrodiffused with Li+ ions at 400℃ with weak electric fields of 20 and 50V/cm and then implanted with Na+ions with an electric field of 200V/cm.As Li+ ions diffused into the sample, the intensities of all the three centers increased. But in the case of electrodiffusion with Na+ ions the resonance signals decreased by considerable. From the effect of heat treatment and the result of electrodiffusions it is proved that all the three centers are compensated by the Li+ion.

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