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김창곤,유수현,이혜원,채정호 大韓神經精神醫學會 2008 신경정신의학 Vol.47 No.4
Objeetives : There have been no consistent reliable and valid tool for examining the psychosocial problems for the patients with mental disorders in Korea. The purpose of the present study is to develop a scale that examine the psychosocial problems for the patients with mental disorders and to test its reliability and validity. Methods : To identify the psychosocial problems for 1,100 patients with mental disorders were selected in university hospitals and professional training institutes. And the items of the psychosocial problems were taken from them and divided them into individual and environmental categories. The representative items were established among these items of psychosocial problems and a questionnaire for a pilot study was made based on the representative items. The pilot study was done for 306 patients with mental disorders using the questionnaire to investigate reliability of the questionnaire. After the pilot study items and format of the questionnaire were revised and complemented. The revised questionnaire was given to 600 patients with mental disorders to test its validity and reliability and new scale for psychosocial problems was developed. Results : At the pilot study, which was performed with 1,100 patients, 3,200 items of psychosocial problems of 205 types were selected. Among these items 78 representative psychosocial problems items were withdrawn. Fifty-eight psychosocial problem items were finally set for the questionnaire after discussing them with the expert groups and examining its content reliability. Forty-seven psychosocial problems items were finally selected and given to 306 subjects at the pilot study. At the main study in which 600 subjects were tested inner-reliability. Correlation between items and scale was relevant and correlation coefficient between test and retest was high. The finally developed psychosocial problems testing scales were consisted of 46 testing items into 9 areas. Conclusion : The Psychosocial Problems Assessment Scale, which were developed at this study is proved to be valid and reliable and it will be able to be used to examine overall psychosocial problems for the patients with mental disorders in Korea.
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Hyewon Jeong,Sun-Hee Moon,Deok Ju,Sun-Hee Seon,Naru Kang 한국간호과학회 2021 한국간호과학회 학술대회 Vol.2021 No.10
Aim(s): This study aimed to develop a clinical core competency empowerment program (CCCEP) according to existing educational guidelines and assess the effectiveness of the developed program. Method(s): A prospective, single-arm repeated-measures, experimental design was used, with nurses" competencies evaluated three times, and educational satisfaction evaluated once after intervention. The CCCEP is a 38-hour, 8-week program comprising three empowerment modules: basic, system-based, and practical competency. The program’s educational contents were composed based on clinical competency items outlined by the Korean Nursing Association’s educational guidelines. Six experts verified the content validity of the program, which was .95. The inclusion criteria were (1) new graduate nurses, and (2) nurses assigned to a ward. The exclusion criteria were nurses who (1) were experienced, (2) resigned during the program, (3) assigned to an intensive care unit or emergency department. The clinical core competency measurement comprised 64 questions and 7 sub-domains, and the study’s reliability was Chronbach"s α=.97. The educational satisfaction tool developed comprised six items rated using a 5-point Likert scale ranging from 1 (not very satisfied) to 5 (very satisfied) and one descriptive item. The CCCEP, led by a clinical nurse educator, was offered to 47 participants, all new graduate nurses, in an educational hospital from March to July 2020. Result(s): Participants’ competency was assessed before, immediately after, and 8 weeks after the CCCEP was implemented. Results indicated that participants’ clinical core competencies had significantly improved following the intervention (F=31.65, p<.001). Specifically, their data collection (F=14.32, p<.001), basic nursing care (F=48.70, p<.001), communication (F=32.35, p<.001), critical thinking (F=9.92, p<.001), teaching and leadership (F=3.72, p<.032), and nursing management (F=8.25, p<.001) showed significant improvement. The average of educational satisfaction was 4.78±0.52. Conclusion(s): These results suggest that the use of the CCCEP could improve new nurses" clinical core competencies and the quality of nursing practice.
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Jeong, Hyewon,Yoon, Sinmyung,Kim, Jung Hwa,Kwak, Do-Hyun,Gu, Da Hwi,Heo, Seung Hwae,Kim, Hyunhong,Park, Sangmin,Ban, Hyeong Woo,Park, Jongnam,Lee, Zonghoon,Lee, Jong-Soo,An, Kwangjin,Son, Jae Sung American Chemical Society 2017 Chemistry of materials Vol.29 No.24
<P>We report a new family of inorganic ligands, namely, transition metal-based thiometallates, for the surface functionalization of colloidal nanocrystals (NCs). We synthesized Pt-, Fe-, Co-, and Ni-based thiometallates, in which transition metal ions were complexed with polysulfides. These inorganic anions easily exchanged the surface organic ligands of various nanocrystals of metal, semiconductor, and oxide materials, without affecting the NCs’ primary structural and optical characteristics. Furthermore, upon heating, these complexes were decomposed and transformed into crystalline phases of metal sulfides or pure metals, accompanied by the evaporation of S. Based on this effect, we selectively synthesized homogeneously distributed atomic Pt clusters or Pt nanoparticles on Fe<SUB>3</SUB>O<SUB>4</SUB> nanomaterials by heating thioplatinate-capped Fe<SUB>3</SUB>O<SUB>4</SUB> NCs. As a model application, we tested the prepared Pt-functionalized Fe<SUB>3</SUB>O<SUB>4</SUB> nanomaterial as a heterogeneous catalyst for CO oxidation reaction and Pt–Fe<SUB>3</SUB>O<SUB>4</SUB> catalysts exhibited the high turnover frequency due to the homogeneous distribution of atomic Pt over Fe<SUB>3</SUB>O<SUB>4</SUB> and the corresponding strong metal–support interaction. This approach opens up a new avenue to functionalize nanocrystals for catalytic applications.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/cmatex/2017/cmatex.2017.29.issue-24/acs.chemmater.7b04387/production/images/medium/cm-2017-04387v_0009.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/cm7b04387'>ACS Electronic Supporting Info</A></P>
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교육전담간호사가 주도한 신규간호사 임상핵심역량강화 프로그램의 효과
Hyewon Jeong,Sun-Hee Moon,Deok Ju,Sun-Hee Seon,Naru Kang 위기관리 이론과 실천 2021 Crisisonomy Vol.17 No.6
본 연구의 목적은 가이드라인에 따른 임상핵심역량강화 프로그램 개발과, 개발된 프로그램의 효과를 검증하는 것이다. 본 연구에서 개발된 임상핵심역량강화 프로그램은 38시간 8주의 교육으로 기본역량, 시스템 기반 역량, 실무역량 강화를 위한 모듈로 구성되었다. 개발된 프로그램은 전문가 내용타당도 검증을 거친 후 2020년 3월부터 7월까지 신규간호사 47명에게 적용되었다. 중재 전, 후, 중재8주 후 임상핵심역량은 유의하게 향상되었다(F=31.65, p<.001). 임상핵심역량의 하부 요인을 살펴보면 자료수집(F=14.32, p<.001), 기본간호(F=48.70, p<.001), 의사소통(F=32.35, p<.001), 비판적 사고(F=9.92, p<.001), 교육과 리더십(F=3.72, p<.032), 간호관리(F=8.25, p<.001)가 유의하게 상승되었다. 임상핵심역량강화 프로그램의 적용은 신규간호사의 임상역량향상과 간호의 질적 향상을 가져올 수있을 것이다. The purpose of this study is to develop the Clinical Core Competency Empowerment Program (CCCEP) according to existing educational guidelines and identify the effectiveness of the developed program. The CCCEP is a 38-hour, 8-week program consisting of three empowerment modules: basic competency, system-based competency, and practical competency. This program was revised through an expert content validity verification process and offered to 47 participants-all new graduate nurses-from March to July 2020. The nurses competency was assessed before, immediately after, and 8 weeks after the CCCEP was rolled out; the results showed that the nurses clinical core competency had significantly increased following the intervention (F=31.65, p <.001). Specifically, the sub-factors of their clinical core competency were significantly improved, including data collection (F=14.32, p <.001), basic nursing care (F=48.70, p <.001), communication (F=32.35, p <.001), critical thinking (F=9.92, p <.001), teaching and leadership (F=3.72, p <.032), and nursing management (F=8.25, p <.001). Therefore, these results suggest that the use of the CCCEP could improve new nurses clinical core competence and the quality of nursing practice.
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( Jeong-ju Yoo ),( Su Jong Yu ),( Juri Na ),( Kyungmin Kim ),( Young Youn Cho ),( Hyeki Cho ),( Dong Hyeon Lee ),( Eun Ju Cho ),( Jeong-hoon Lee ),( Yoon Jun Kim ),( Chung Yong Kim ),( Hyewon Youn ),( 대한간학회 2016 춘·추계 학술대회 (KASL) Vol.2016 No.1
Aims: Enhancing sorafenib sensitivity is essential for achieving efficient control of intractable hepatocellular carcinoma (HCC). Considering that sorafenib exerts its effect by endoplasmic reticulum (ER) stress due to hypoxia and energy depletion through anti-angiogenic aspect, hexokinase (HK) II which is an important rate-limiting glycolytic enzyme can be a key player in countervailing the effect of sorafenib. Pyruvate analog 3-bromopyruvate (3-BP), a HK II inhibitor, can promote tumor cell death by augmenting endoplasmic reticulum (ER) stress in human HCC cell lines. We evaluated inhibition of HK II potentiated sorafenib-induced ER stress in HCC cells. We also postulated that simultaneous treatment with sorafenib and 3-BP might synergistically enhance their anti-tumor efficacies against HCCs in vivo models. Methods: HCC apoptotic cell death was assessed by DAPI staining and apoptotic signaling pathways were explored by immunoblot analysis. Energy depletion was assessed by lactate assay. In vivo ectopic model of HCC was established in BALB-c nu/nu mice intradermally implanted with SNU-761 cells. Moreover, orthotopic model of HCC was established by subcapsular injection of SNU-761 cells via mini-laparotomy in BALB-c nu/nu mice. Sorafenib with/without 3-BP was subsequently administered. The anti-tumor efficacies were
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