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      • 중년층의 비처방약품 오남용 실태 연구

        고미현,김민주,김유진,김정호,박예진,유리호,이민영,이송연,조윤진,황선주 이화여자대학교 간호과학대학 2014 이화간호학회지 Vol.- No.48

        Purpose: The purpose of this study was to grasp the status of abusing Over The Counter Drug (OTC Drug) among the middle-aged. Methods: The participants of this study consisted of 175 middle-aged people in Seoul and Gyeoggi-do. Data were collected using a questionnaire, and the study was conducted from September 10 to October 10, 2013. The data were analyzed by t-test, chi-square test, one-way ANOVA and Turkey. Results : As a result, 97 participants(55.4%) out of 175 participants of this study had taken over the counter drug within the past one year. Their average score of abusive behavior of OTC drug was 6.96±3.01 out of 16. There was significant abusive behavior of OTC drug relative to the difference in family monthly income.(F=3.455, p=0.20) and there was significant difference depending on the information source of the OTC Drug.(F=2.56, p=.044) Conclusions : In conclusion, nurses should educate middle-aged people so that they can use over the counter drug more safely and accurately based on these results. In addition, these results will be useful in further studies regarding middle-aged people’s drug abuse according to the preceding data.

      • 여대생 1인가구의 사회적지지, 주거환경, 식습관과 건강 관련 삶의 질의 상관관계 연구

        구정연,김근영,김다희,김선미,김수연,김지아,배춘화,임혜윤,최유현,황선영,정덕유,김지연 이화여자대학교 간호과학대학 2017 이화간호학회지 Vol.- No.51

        Purpose: The purpose of this study was to investigate the health-related quality of life (HRQOL) among female college students living alone and analyze the relationship among HRQOL, eating habits, residential environments and social support among female college students living alone. Method: Using a descriptive correlation study design, 151 female college students living alone were recruited through convenience sampling. Instruments were the social support tool developed by Park(1985), residential environment tool developed by Kim and Nam(2015), eating habit tool developed by Park et al(2005), modified by Choi(2012) and the HRQOL tool developed by EuroQol Group(1990). The data were analyzed by average, standard deviation, percentage, t-test, ANOVA, and scheffe test, Pearson’s correlation coefficient using the SPSS 22.0 Version program. Results: Participants’ economic level showed statistically significant differences in social support.(F=4.33, p=.009). There was a statically significant relationship among the types of resident and residential environment evaluation score.(F=4.33, p=.009). Also, there were correlations between HRQOL and social support(Pearson’s r=.165, p=.043), residential environment evaluation score.(r=.284, p<.001). There was a correlation between social support and residential environment evaluation score(r=.202, p=.013). Eating habit showed a correlation between emotional support(r=.164, p=.044) and residential environment evaluation score(r=.200, p=.014). However, perceived health status and eating habit were not significantly associated with HRQOL. Conclusion: As a result of this study, the following conclusions were obtained. There were strong relationships among social support, residential environment and HRQOL in female college students living alone. These findings implied the importance of framing university's guideline and overnment’s policy such as financial support, residential counsel and mental health programs to improve HRQOL for female college students living alone. Since the importance of HRQOL has acquired a great importance, it is critical to collect the data of related factors of HRQOL considering only little research on female college students living alone has been done.

      • SCIESCOPUSKCI등재

        Amplification of Porcine SRY Gene for Sex Determination

        Choi, S.G.,Bae, M.S.,Lee, E.S.,Kim, S.O.,Kim, B.K.,Yang, J.H.,Jeon, C.E.,Kim, H.H.,Hwang, Y.J.,Lee, E.S.,Kim, D.Y. Asian Australasian Association of Animal Productio 2009 Animal Bioscience Vol.22 No.8

        The separation of X and Y chromosome-bearing sperm is of use in many aspects of livestock maintenance. In this study, we sought to determine the difference in DNA content between X- and Y-bearing sperm, separate sperm into X- and Y-enriched pools, and assess the efficacy of sorting. Sperm collected from Duroc and miniature pigs were stained with 20.8 $\mu{M}$ Hoechst 33342 and analyzed using a high-speed cell sorter. Measurement of the fluorescence intensity of stained sperm nuclei revealed that the X-bearing sperm of Duroc and miniature pigs respectively contain 2.75% and 2.88% more DNA than Y-bearing sperm. In total, 50.18% of the sperm were assigned to the X-sorted sample and 49.82% was assigned to the Y-sorted sample for Duroc pigs. For miniature pigs, the Xsorted sample represented 50.19% of the population and the Y-sorted represented 49.81% of the population. Duplex PCR was used to evaluate accuracy of sorting. A fast and reliable method for porcine sexing was developed through amplification of the sex-determining region of the Y chromosome gene (SRY). Oligonucleotide primers were designed to amplify the conserved porcine SRY high motility group (HMG) box sequence motif. We found that the primer pair designed in this study was 1.46 times more specific than previously reported primers. Thus, this study shows that the present method can be applied in porcine breeding programs to facilitate manipulation of the sex ratio of offspring and to achieve precise sexing of porcine offspring by amplification of the HMG box of the SRY gene.

      • Novel dentin phosphoprotein frameshift mutations in dentinogenesis imperfecta type II

        Lee, K‐,E,Kang, H‐,Y,Lee, S‐,K,Yoo, S‐,H,Lee, J,C,Hwang, Y,H,Nam, KH,Kim, J,S,Park, J,C,Kim, J,W Blackwell Publishing Ltd 2011 Clinical genetics Vol.79 No.4

        <P>Lee K‐E, Kang H‐Y, Lee S‐K, Yoo S‐H, Lee J‐C, Hwang Y‐H, Nam KH, Kim J‐S, Park J‐C, Kim J‐W. Novel dentin phosphoprotein frameshift mutations in dentinogenesis imperfecta type II.</P><P>The dentin sialophosphoprotein (<I>DSPP</I>) gene encodes the most abundant non‐collagenous protein in tooth dentin and DSPP protein is cleaved into several segments including the highly phosphorylated dentin phosphoprotein (DPP). Mutations in the <I>DSPP</I> gene have been solely related to non‐syndromic form of hereditary dentin defects. We recruited three Korean families with dentinogenesis imperfecta (DGI) type II and sequenced the exons and exon–intron boundaries of the <I>DSPP</I> gene based on the candidate gene approach. Direct sequencing of PCR products and allele‐specific cloning of the highly repetitive exon 5 revealed novel single base pair (bp) deletional mutations (c.2688delT and c.3560delG) introducing hydrophobic amino acids in the hydrophilic repeat domain of the DPP coding region. All affected members of the three families showed exceptionally rapid pulp chambers obliteration, even before tooth eruption. Individuals with the c.3560delG mutation showed only mild, yellowish tooth discoloration, in contrast to the affected individuals from two families with c.2688delT mutation. We believe that these results will help us to understand the molecular pathogenesis of DGI type II as well as the normal process of dentin biomineralization.</P>

      • 약산의 해리반응에 미치는 압력의 영향

        黃正儀,鄭倧在,朴龍泰,池鍾基,박은숙 慶北大學校 物理化學硏究所 1984 硏究論文集 Vol.5 No.-

        Anilinium ion, o-toluidinium ion, phenol 및 o-chorophenol의 해리상수를 10∼40℃ 온도범위와 1∼2000 bar의 압력범위에서 분광광도법으로 측정하였다. phenols에서는 일반적인 약산에서처럼 온도와 압력이 증가할수록 해리상수가 증가하였으나 anilinium ions의 해리상수는 온도가 증가할수록 증가하였고, 압력이 증가할수록 감소하였다. 해리상수의 압력의 효과는 해리반응시의 하전의 증감으로 설명된다. 즉 phenols와 같이 하전이 증가하는 산은 압력이 증가할수록 해리상수가 증가하나 anilinium ions와 같이 하전의 증감이 없으면 해리상수는 감소한다. 이들 해리상수값에서 열역학적 파라미터, ΔH˚, ΔG˚, ΔS˚, ΔV˚ 및 β를 계산하고 해리반응의 성질을 고찰하였다. The dissociation constants of anilinium ion, o-toluidinium ion, phenol and o-chlorophenol were measured spectroscopically in aqueous solution over the temperature range of 10∼40℃ and at the pressures up to 2,000 bars. The effects of temperature and pressure on the dissociation of the phenols are the same as those of the ordinary weak acids. Meanwhile the dissociation constants of anilinium ions are increased with temperature raising and decreased with pressure elevation. The effects of pressure on the constants can be explained by taking account of change of charge during dissociation reaction; there are increase in charge in the dissociation of phenols but anilinium ions are not. Several thermodynamic properties, ΔH˚, ΔG˚, ΔS˚, ΔV˚ and β are calculated from those constants, and the dissociation reactions are discussed by item.

      • 여대생의 우울, 스트레스와 문제도박과의 관계

        하주희,차민주,조에스더,조세빈,홍소리,황정민,박지윤,강하영,노규상 이화여자대학교 간호과학대학 2015 이화간호학회지 Vol.- No.49

        Purpose: The purpose of this study was to learn about problem-gambling level, depression and stress among female college students. Method: In this cross-sectional design study, a convenient sample of 325 female college students were recruited between September and October, 2014. Measurement used for this study were the CPGI(Canadian Problem Gambling Index), the CES-D(Center for Epidemiologic Studies Depression Scale), and the Life stress scale for college students. Data were statistically analyzed using descriptive statistics, t-test, ANOVA and chi-square test. Result: About 58.5 percent of the participants had experience of gambling; lottery was the most frequently used gambling among participants. 36 participants(11.1%) were problem gamblers. Relationship of smoking status to problem gambler group was statistically significant. There were statistically significant relationships among problem-gambling level(Non-problem, Low-risk, Moderate-risk, High-risk), depression and stress. The problem gambler group had significantly higher trait stress scores compared to the normal group. Conclusion: Problem gambling was a risk factor for both depression and stress among female college students. The proposals of this study are as follows; first, in depth-research are required with more expanded sampling as sample of this study was conveniently gathered, it is hard to generalize the result. Second, a problem gambling prevention program is recommended for low-risk problem gamblers as they have risk to become problem gambler later. Third, nursing interventions for problem gamblers should be investigated with regard to depression and stress level.

      • SCOPUSKCI등재

        Lateral Calcaneal Flap을 이용한 발꿈치 피부 결손의 치험례

        황오열,박정준,김용배,이종현 大韓成形外科學會 1986 Archives of Plastic Surgery Vol.13 No.2

        The heel and sole are vital musculoskeketal structures, responsible for weight bearing, shock absoption, and locomotion. Many reports have been published on the method of reconstructing a skin defect of the posterior heel and plantar heel, that is, ways of skin graft, innervated skin graft, local skin flap, neurovascular skin island flap (local delayed medial plantar, lateral plantar and dorsalis pedis), muscle flap (flexor digitorum brevis), neurovascular free flap (free groin, free dorsalis, free deltoid, free scapular, free Post. arm). In repair of a defect of the posterior heel, a relatively small, sensory flap is desirable and the lateral calcaneal flap is suitable for this purpose. The lateral calcaneal flap provides another modality for soft-tissue coverage when there is exposed of the calcaneal tendon or Os calcis on the posterior and/or plantar heel. There is a short and long version of this flap We present 3 cases of defects of the posterior heel with a favorable result.

      • KCI등재

        M20J 시뮬레이터 개발을 위한 시스템 통합

        홍승범,김용환,정식항,백중환,황수찬,황명신,김칠영 한국항공운항학회 1999 한국항공운항학회지 Vol.7 No.1

        This paper proposes a system intergration method for M20J flight simulator development. The simulator consists of three modules. The first module is for flight dynamics simulation, and the second module is for avionic systems and flight instrument and the last module is for interface card which connects PC and input devices using rotary encoders and switches. Two computers are equipped in the simulator for instructor and trainee. An instructor can give a mission to a trainee, and control the flight simulation options through RS-232C serial port. Also, the instructor can monitor the training results of the trainee

      • KCI등재

        Quasi-Monoenergetic Electron-Beam Generation Using a Laser Accelerator for Ultra-Short X-ray Sources

        J Kim,고도경,석희용,H Jang,김형택,I Hwang,최일우,J Lim,J. Lee,J. H. Sung,K.-H. Hong,허민섭,N Hafz,유승훈,유태준,T. M. Jeong,V Kulagin,Y.-C. Noh 한국물리학회 2007 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.51 No.I

        Two types of electron acceleration methods have been conducted to generate quasi-monoenergetic electron beams. Multi-MeV quasi-monoenergetic high-charge electron beams were generated at Korea Electrotechnology Research Institute (KERI) from self-modulated laser wakefield acceleration by using a collimator with a 2 TW (1.4 J/700 fs) Nd:glass/Ti:sapphire hybrid laser system and a supersonic nitrogen gas jet. The peak electron energy was 3.6 MeV, and the energy spread was 4 MeV. These electron beams are useful for the generation of short-pulse X-rays in the water window region, which is 250 eV -- 500 eV (2.5 -- 5 nm), by using Thomson scattering. The calcualted photon spectrum indicates the scattered photon covers the water window region. This can be used for a high spatial and temperal resolution microscope for medical imaing. To generate higher-energy electron beams with small energy spread, a laser wakefield acceleration experiment with a sharp downward electron density gradient was conducted with a 100 TW laser system at Advanced Photon Research Insistitute (APRI). With the electron density gradient, some background plasma electrons could be locally injected in the laser wake wave and a small energy spread was expected. Using the pre-pulse, we could generate sharp downward electron density gradients. The gradient scale length was 20 $\mu$m for a 25 \% density change. With this electron density gradient, we could get more reproducible electron beams than we could without the density gradient.

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