中學校 科學科의 實驗實習敎材의 開發硏究Ⅱ

朴泳喆,韓麟傳,李春雨,權寧駿,朴弘緖 공주대학교 사범대학 과학교육연구소 1982 과학교육연구 Vol.14 No.1

In this study a few laboratory teaching materials have been developed to be available for the effective performance of experiments and practices- a heart of inquiry learning-as a continuance of 'A study on the Development of Laboratory Teaching Materials for Middle School Science Course I' The present condition of science education has been investigated by means of questionaires, interviews and literature, the results of the present condition and problems in junior high schools are as follows: 1. The hours for science classes are considerably little for the teaching contents of science textbooks. 2. The level of teaching is beyond the student's capability in terms of their experience and intellectual development. 3. Science teachers are overburdened with much tasks, and laboratories and laboratory facilities are too insufficient and furthermore teaching is mainly conducted on the lecture method as a preperation for various entrance exams. 4. Teachers' eagerness and desirable attitude for teaching are required. In this study, materials for every branch of science have been developed to be available for the effective performance of experiments and practices through inquiries. The materials developed in this study are as follows: 1. In physics, measure apparatus of extremely small masses, length, and very little time intervals are developed. 2. In chemistry, new methods for gas generating apparatus and materials. are developed. 3. In biology, the size of quadrate and the method to decide the time in facilitating for the purpose of survey of botany community are introduced. The results of the investigation of natural enemy on Hyphantria cunea, and the study on collecting, breeding of Planaria are also shown. 4. In earth science, the laboratory teaching materials are developed for observing continuous spectrum and line spectrum. Putting the above results of study together, the suggestions are made to the effect as follows: 1. The quantity of learning should be reduced and the levels lowered in the new textbooks. 2. The development and distribution of various teaching materials(film, T,P., cassettes film, supplementary, textbook, program teaching material, individual learning material) is required. 3. The experimental instruments should be timely manufactured and distributed on the basis of effective administrative support to ensure their solidity and accuracy. 4. The concrete design to eliminate the teacher's burden should be contrived and the system for senion teachers in charge of science teaching in secondary schools, should be improved. 5. Teacher's research activities should be encouraged through various research institutes(Institute of science education , graduate school of education and the other research institutes.) 6. The disposition of laboratory assistant should be considered. 7. More positive supports from other societies relevant with education are much expected to be made.

안면중앙부 골절 진단시 전산화단층사진과 Waters 방사선사진의 진단능 비교

전인성,최순철 大韓口腔顎顔面 放射線學會 1997 Imaging Science in Dentistry Vol.27 No.1

This study was intended to compare the diagnostic ability between Waters' radiograph and CT in the diagnosis of midfacial fracture. The study group included 44 patients(male:32, female:12, age range:16-74 years old) with facial injury who underwent surgery. Waters' radiograph and both axial and coronal scanning were performed before surgery. Three oral radiologists and three non-oral radiologist interpreted 44 Waters' radiographs and 88 CT in three ways; 1) interpretation using Waters' radiograph only, 2) interpretation using CT only, 3) interpretation using Waters' radiograph and CT. The interpretation sites were confined to the walls of maxillary sinus; anterior, posterior, medial, lateral and superior wall. ROC curves were made with the findings during surgery as a gold standard except the posterior wall, where the joint evaluation of Waters' radiograph and CT by other three oral radiologists was used. ROC areas were compared according to the interpreting methods, the interpretation sites, and groups (R group ; oral radiologist group, N group ; non-oral radiologist group). The obtained results were as followed: 1. The diagnostic ability of CT only and Waters' radiograph and CT was higher than Waters' radiograph only in both groups(P<0.05). But there was no difference between CT only and Waters' radiograph and CT. 2. Generally, the diagnostic ability for the lateral antral wall was the highest and that for the posterior antral wall was the lowest in both groups(P<0.05). 3. In R group, for the anterior antral wall the diagnostic ability using CT only was increased but for the medial, lateral and superior antral walls the diagnostic ability was increased in only using Waters' radiograph and CT. 4. In N group, for the anterior and medial walls the diagnostic ability using CT only was increased. But for the posterior, lateral and superior antral walls there were no difference among three interpreting methods. 5. The diagnostic ability of R group was higher than N group in all interpreting methods.

DMBA 유도 햄스터 협낭암 발생과정에서 방사선 조사가 증식세포핵항원(PCNA)의 발현과 apoptosis 유발에 미치는 영향

전인성,허민석,최항문,이삼선,최순철 대한구강악안면방사선학회 2000 Imaging Science in Dentistry Vol.30 No.3

Purpose : This study was carried out to investigate the effect of irradiation on the expression of proliferating cell nuclear antigen (PCNA) and apoptosis induction during the carcinogenesis in hamster buccal pouch. Materials and methods : Three months old Syrian golden hamsters were divided into control and 2 experimental groups, Hamsters in control group were left untreated on buccal pouchs. Twenty four hamsters were treated with 0.5% DMBA tri-weekly on the right buccal pouch. Forty eight hamsters were treated with 0.5% DMBA tri-weekly and irradiated with the dose of 5 Gy and 10 Gy at 6,9, 12, 15 weeks after DMBA application. Resected buccal pouches were sectioned and examined for potential expression pattern of PCNA and apoptosis. Results : The PCNA index was increased with the stages of buccal pouch epithelium carcinogenesis except the hyperplasia stage in control group (p< 0.05). The irradiation did not effect on the PCNA index in the dysplasia and the carcinoma in situ stage, but in the hyperplasia stage, the PCNA index was increased with 10 Gy radiation and decreased in the carcinoma stage (p< 0.05). The apoptotic index was significantly decreased from the carcinoma in situ stage and the lowest in the carcinoma stage, The apoptotic index was significantly decreased in the hyperplasia and dysplasia stage with the 5 Gy irradiation and significantly increased only in the carcinoma stage with the 10 Gy irradiation (p< 0.05). Conclusion : The PCNA and apoptotic index were varied according to the irradiation period and dosage in each carcinogenesis stage. (Korean J Oral Maxillofac Radiol 2000; 30: 207-216)

저강도 초음파 및 레이저를 이용한 장관골 불유합의 치료

전인호,오창욱,김성중,경희수,박일형,박병철,인주철,여준영 대한골절학회 2003 대한골절학회지 Vol.16 No.2

목 적: 저강도 초음파는 인체 및 동물 실험에서 골조직에 낮은 미세한 물리적 압력을 가하여 골절의 치유에 유리한 영향을 주고, 레이저 (LASER)는 심부 조직에 혈류를 증가시키고, 세포 내 잠재된 에너지를 증가시키는 것으로 알려져 있다. 이에 저자들은 임상적으로 확진된 장관골 붕류합의 치료에 있어 펄스형 저강도 초음파와 레이저를 적용하고 그 효용성을 알아보고자 하였다. 대상 및 방법: 초음파/레이저의 치료 효과를 비교하기 위하여 장관골 불유합으로 확진된 16예 중 8예는 연구군으로 골이식술 후 저강도 초음파와 레이저 치료를 추가하였고 대조군 8예에 대해선 일반적인 골이식술만 시행하여 조사하였다. 남자가 11예, 여자가 5예, 평균 연령은 41.7세 (19~62세)였고, 불유합 부위는 대퇴골이 10예, 경골이 6예였다. 첫 수상으로 인한 골절 후 초음파/레이저 치료까지 시간(골절 연력)은 평균 502일이었다. 결 과: 8예의 연구군에서는 완전 골유합이 6예에서 이루어졌으며 유합까지의 시간은 평균 141일 (101~202일)로 나타난 반면, 8례ㅢ 대조군에서는 5예에서 골유합이 이루어졌고, 유합까지의 시간은 평균 240일 (183~283일)이었다. 결 론: 저강도 초음파/레이져 골절 치료기가 반복된 수술로 인한 난치성 장관골 불유합의 치료에 있어 골이식술과 함께 사용될 경우 긍정적인 효과가 있었고, 특히 최초 가골 형성에 있어 대조군에 비해 그 시간을 줄일 수 있었따. Purpose: Low-intensity, pulsed ultrasound (LIPUS) has demonstrated a stimulation and acceleration of the normal fracture-repair process in cellular bases as well in animal and human models. In this study, the adjunctive effect of LIPUS and LASER was investigated in established nonunion of the long bones. Materials and Methods: Study group consisted of eight patients to whom conventional bone graft and adjunctive LIPUS and LASER was applied. On the other hands, eight patients in the control group underwent bone graft only. Eleven men and five women were included in this study and the average age of the patients was 41.7 years (range, 19~62 years). Six of the tibias and ten of the femurs met the criteria for established nonunion. The average fracture age, the post-fracture period before the start of LIPUS/LASER treatment, was 502 days. Results: Seven of the ten nonunions who were treated by LIPUS and LASER healed completely in an average treatment time of 141 days (range, 101~202 days) and otherwise, in control group, five of the eight nonunions healed completely, in 240 days (range 183~283 days). Conclusion: This clinical study showed a positive effect of LIPUS and LASER on the rate of osseous repair, especially accelerated time to initial callus cortical bridging compared to that of conventional treatment.

특수교육대상학생 교육과정 운영에 대한 특수학급 교사 및 통합학급 교사의 인식

전혜인(Hae-In Jeon),정효철(Hyo-Chul Jeong) 한국콘텐츠학회 2021 한국콘텐츠학회논문지 Vol.21 No.5

특수교육 현장에서 특수교육대상학생들을 위한 교육과정 운영은 특수교사 및 통합학급 교사들에게 주어지는 역할인데, 많은 교사들이 교육과정 운영에 어려움을 경험한다는 선행연구들이 있다. 본 연구에서는 질적연구방법을 통해 특수교사와 통합학급 교사들의 교육과정 운영 경험 및 교육과정 운영의 어려움과 제안사항 등에 대해 알아보는 것을 통해 특수교육대상학생 교육과정 운영의 방향을 모색하고 교육과정 운영을 위한 적합한 지원방안을 찾고자 하였다. 본 연구의 참여자는 경력 15년 이상의 특수교사 및 통합학급 교사를 대상으로 이루어졌으며 모든 면담은 일대일 심층면담으로 실시하였다. 모든 면담을 전사본으로 작성 후, 지속적 비교법을 통해 분석한 결과 대주제 6가지와 하위주제 12가지가 도출되었으며 도출된 대주제와 하위 주제는 다음과 같다; 교사마다 다른 교육과정 운영, 교육과정 적용의 어려움, 부족한 지원체계, 전문적 자질 문제, 통합학급에서 더 어려운 특수교육 교육과정, 통학학급 교사의 매일의 고민. 논의에서는 특수교육대상학생 교육과정 운영의 방향과 교육과정 운영을 위한 적합한 지원방안에 대해 논의하고, 연구의 제한점을 제시하며 제언하였다. In special education, the operation of curriculum for students subject to special education is a role given to special teachers and integrated class teachers, and there are prior studies that many teachers experience difficulties in operating the curriculum. In this study, it was intended to find out the direction of special education courses and appropriate support measures for the operation of special education courses by exploring the experiences of special teachers and integrated class teachers, difficulties and suggestions in operating the curriculum. Participants in this study were special and integrated teachers with more than 15 years of experience, and all interviews were conducted in one-on-one in-depth interviews. After all the interviews have been prepared in full-length versions, the analysis has resulted in six major subjects and twelve subtopics; each teacher has different curriculum operations, difficulties in applying the curriculum, insufficient support systems, professional qualifications, and daily concerns of teachers in integrated classes. In the discussion, the direction of operation of special education courses for students and appropriate support measures for the operation of curriculum were discussed, and the limitations of research were presented and proposed.

Isolation of a novel protein phosphatase2C in rice and its response to gibberellin

Amir Hossain, Md,Ahn, Chul-Hyun,Lee, In Suk,Jeon, Jong-Seong,An, Gynheung,Park, Phun Bum Elsevier 2018 Biochemical and biophysical research communication Vol.503 No.3

<P><B>Abstract</B></P> <P>Protein phosphatase 2Cs (PP2Cs) have been referred to act as negative modulators of the protein kinase pathways involved in different environmental stress responses and developmental processes. In <I>Arabidopsis</I>, PP2Cs have been extensively studied and some are known to negatively regulate abscisic acid signaling. In rice, PP2Cs are scarcely characterized functionally. Here, we identified a novel PP2C from rice (OsPP2C34), which is highly inducible by gibberellin (GA) and expressed in various tissues. Subcellular localization analysis in maize protoplasts using a green fluorescence protein fusion vector localized OsPP2C34 to the cytosol. Genetic analysis of T-DNA insertional mutants revealed that plant height and internode length were significantly shorter in mutants than in corresponding wild types under GA treatment. The induction of the GA-inducibleα-amylase genes <I>RAmy3E</I> and <I>OsAmy</I> was delayed in mutant plants. The substrate of OsPP2C34 was identified by immunoblotting using anti serine/threonine antibodies. A 65 kDa protein was phosphorylated in <I>Ospp2c34-1</I> but dephosphorylated in the wild type during early germination stage. Overall, the present results indicated that OsPP2C34 is involved inα-amylase expression of GA signal transduction pathway.</P> <P><B>Highlights</B></P> <P> <UL> <LI> OsPP2C34 is highly inducible by gibberellin (GA) and expressed in various tissues. </LI> <LI> OsPP2C34 is localized to the cytosol and involved in α-amylase genes inducible by GA. </LI> <LI> OsPP2C34 has dephosphorylation activity at its serine/threonine residues. </LI> <LI> OsPP2C34 is a positive regulator of the GA-dependent signaling transduction pathway. </LI> </UL> </P>

The Clinical Profile of Patients with Psoriasis in Korea: A Nationwide Cross-Sectional Study (EPI-PSODE)

( Hae Jun Song ),( Chul Jong Park ),( Tae Yoon Kim ),( Yong Beom Choe ),( Seok-Jong Lee ),( Nack In Kim ),( Jae We Cho ),( Jie Hyun Jeon ),( Min Soo Jang ),( Jai Il Youn ),( Myung Hwa Kim ),( Joonsoo 대한피부과학회 2017 Annals of Dermatology Vol.29 No.4

Background: Psoriasis is an immune-mediated, chronic in-flammatory disease affecting multiple aspects of patients` lives. Its epidemiology varies regionally; however, nation-wide epidemiologic data on psoriasis depicting profile of Korean patients has not been available to date. Objective: To understand nationwide epidemiologic characteristics and clinical features of adult patients with psoriasis visited uni-versity hospitals in Korea. Methods: This multicenter, non-in-terventional, cross-sectional study recruited 1,278 adult pa-tients with psoriasis across 25 centers in Korea in 2013. Various clinical data including PASI, BSA, DLQI, SF-36 and PASE were collected. Results: A total of 1,260 patients com-pleted the study (male:female=1.47:1). The mean age was 47.0 years with a distribution mostly in the 50s (24.9%). Early onset (<40 years) of psoriasis accounted for 53.9% of patients. The mean disease duration was 109.2 months; mean body mass index was 23.9 kg/m2; and 12.7% of patients had a family history of psoriasis. Plaque and guttate types of psoriasis accounted for 85.8% and 8.4%, respectively. Patients with PASI ≥10 accounted for 24.9%; patients with body surface area ≥10 were 45.9%. Patients with DLQI ≥6 accounted for 78.8%. Between PASI <10 and PASI ≥10 groups, significant difference was noted in age at diagnosis, disease duration, blood pressure, waist cir-cumference of female, and treatment experiences with pho-totherapy, systemic agents, and biologics. Conclusion: This was the first nationwide epidemiologic study of patients with psoriasis in Korea and provides an overview of the epidemio-logic characteristics and clinical profiles of this patient population. (Ann Dermatol 29(4) 462∼470, 2017)

골수강내 금속정을 이용한 경골 근위간부 골절의 치료 : AO 골절형과 Poller 나사 사용 유무에 따른 분석 Analysis According to AO Classification and the Poller Screw

오창욱,김성중,전인호,경희수,박병철,인주철,김경훈,우연기 대한골절학회 2004 대한골절학회지 Vol.17 No.2

이동물체의 기하학적 특성에 기인한 움직임 정보 추출

박인전,오미숙,백경주,정영철,김신규,박종안 조선대학교 전자정보통신연구소 2002 電子情報通信硏究所論文誌 Vol.5 No.1

In this paper, we have proposed an effective moving objects tracking method based on the motion information in the video sequence. First, we extract the moving objects using the processes of morphological dilation and differential image in the video sequence and then we extract the motion information utilizing the location and orientation of the moving objects in the subsequent images. The motion information is extracted using various statistical measurements, extracting the high-level features from the regions of pixels in the images. The measurements, such a s area, length, perimeter, orientation, elongation, compactness, moments of inertia, are used as the statistical and geometrical descriptors. The principle axes of an object on this features gives the local direction of the object, while the center of gravity gives the center position of the object. The angle between two principal axes of the moving objects in the consecutive images gives the geometrical direction of the moving object, while the displacement of the center of gravity, gives the distance covered by the moving objects. So we have extracted the global motion information using the principal axes and center of gravity. The simulation results on the test images are very good, where either the motion is very slow, or the frame rate is very high.

불명열 환자에서 진단된 중증 만성 활동성 Epstein-Barr virus 감염증

전경만,김응호,손준성,장현하,정숙인,오원섭,백경란,송재훈,고광철,정철원,고영혜 대한감염학회 2003 감염과 화학요법 Vol.35 No.4

최근 장기적이고 심각한 임상 증상을 유발하는 만성 활동성 EBV 감염증의 개념이 정립되면서 그 증례들이 보고되고 있다. 만성 활동성 EBV 감염증은 소아나 젊은 성인들에게서 주로 발생되며, EBV-VCA IgG, EBV-EA IgG의 수치가 높게 관찰되고, 지속적인 발열, 전신쇠약감, 광범위한 임파선비대증, 간비장비대, 범혈구감소증, 다크론성감마병증을 나타낸다. 이 질환은 환자의 임상소견, 혈액학적 소견, EBV 항체 역가 및 침범 장기의 EBV genome 검출로 확진 되며 치료로 항 바이러스 체제, 항암 치료, 골수이식술 등이 시도되고 있으나 아직 검증되어 있지 않다. 저자들은 불명열을 주소로 내원하여 중증 만성 활동성 EBV 감염증으로 진단된 증례 4례를 경험하였다. 한 례에서는 항 바이러스 제제를 추여 후 임상적, 혈액학적 호전을 보였으나 치료 20일째 발생한 세균성 복막염과 패혈증으로 사망하였고, 두 례에서 총 6회의 CHOP 항암치료와 자가조혈모세포이식을 시행 받은 후 현재까지 증상 없이 추적관찰 중이다. 지속되는 발열을 주소로 내원한 불명열 환자들에게서 EBV에 대한 검사를 시행할 경우 불명열의 원인을 규명하는데 하나의 단서를 제공할 수 있을 것으로 사료된다. Epstein-Barr virus (EBV) is one of eight human herpesvirus. Primary infection with EBV in childhood is generally asymptomatic or mild, however, often causes overt diseases such as infectious mononucleosis (IM) and lymphoproliferative disorder (LPD), the latter occursing in immunologically compromised individuals. Historically, EBV has been considered to be etiologically linked to human malignancies such as EBV genome positive Burkitt's lymphoma and nasopharyngeal carcinoma. Recently, however, another category of EBV-related disease, "chronic active EBV infection", has been made to describe persons without a clearly defined underlying disease. We report 4 cases of patients, presented with episodic fever of unknown origin (FUO), who were diagnosed as severe chronic active EBV infection. A combined application of serology for EBV and in-situ hybridization established the diagnosis of the EBV infection.