축구선수의 Detraining과 Retraining이 혈청지질 및 호르몬농도에 미치는 영향

정정화,박재현,채종훈,성혜련,황지인,윤미숙,노금선,윤종관,윤영학,노순덕,정경숙,박일규,김은희,박현태,박상갑 대한스포츠의학회 1999 대한스포츠의학회지 Vol.17 No.1

The purpose of this study was to investigate the effects of detraining and retraining on serum lipid and hormones in soccer players. Subjects were seven male high-school soccer players. V˙O_2max was determined for each subjects by administering a treadmill test(initial speed: 90m/min, grade: 5%, increasing speed per 3 min: 30m/min). Serum lipid(T-C, TG, HDL-C LDL-C) and hormones(epinephrine, norepinephrine, growth hormones, cortisol) were assayed pre and post detraining in 10, 20, 30 days after retraining. The repeated ANOVA was used to determine significant differences. The 0.05 level of significance was as critical level for the study. The results of the study were as follows: 1. V˙O_2max(ml/min) were 3576.3±204.2ml/min pre detraining, 3234.1±198.9 ml/min post detraining. There are significant(p<.05) difference between pre and post detraining. In 10, 20, 30 days after retraining, V˙O_2max(ml/min) were 3601.4±170.9 ml/min. There were significantly(p<.05) increased in retraining periods. 2. V˙O_2max(ml/kg/min) were significantly(p<.05) decreased from 62.3±2.9 ml/kg/min to 55.9±4.7 ml/kg/min in detraining. In 10, 20, 30 days after retraining, V˙O_2max(ml/kg/min) were 62.4±3.4ml/kg/min, 62.7±2.3ml.kg/min, 67.3±7.2ml/kg/min respectively. There were significantly(p<.05) increased in retraining periods. 3. T-C were significantly (p<.05) increased from 166.6±8.5mg/dl to 175.3±10.3 mg/dl in detraining. In 10, 20, 30 days after retraining, T-C were 160.1± 3.2mg/dl, 156.7±3.7mg/dl, 140.3±9.0mg/dl. There were significantly(p<.05) decreased in retraining periods. 4. HDL-C were 61.4±6.6mg/di pre detraining, 5.3±6.6mg/dl post detraining. There are significant(p<.05) difference between pre and post detraining. In 10, 20, 30 days after retraining, HDL-C were 56.9±7.1mg/dl, 56.4±9.2mg/dl, 57.7±9.1mg/dl respectively. There were no significant difference in retraining periods. 5. The hormones(epinephrine. norepinephrine, growth hormone, cortisol) were changed as same patterns. Epinephrine were 26.0±7.0[g/ml pre detraining, 24.6±3.2pg/ml post detraining. In 10, 20, 30 days after retraining, epinephrine were 26.9±5.6pg/ml, 30.6±6.2pg/ml, 29.4±5.6pg/ml respectively. There were no significant difference in retraining periods. In conclusion, HDL-C, epinephrine, norepinephrine, growth hormone and cortisol were decreased, T-C, LDL-C and TG were increased in detraining. But HDL-C, epinephrine, norepinephrine, growth hormone and cortisol were increased, T-C, LDL-C and TG were decreased in retraining.

개에서 이중 결찰법을 통한 동맥관 개존증의 완치 예

윤헌영,정순욱,박희명,박철,정만복,김준영,한현정,황민,노병국,박상혁,장하영,박정윤 한국임상수의학회 2004 한국임상수의학회지 Vol.21 No.1

A ten months old, female Yorkshire terrier weighing 2.88 kg referred to veterinary teaching hospital of college of veterinary medicine, Konkuk University because of syncope, cough and dyspnea. First hematological and serum chemical test revealed thrombocytopenia, mild anemia, and increase of concentration of ALP (195 U/L). On 57 days later, second hematological and serum chemical test revealed polycythemia, increase of concentration of ALP (211 U/L), and Tchol (387 mg/dl). Right atrium enlargement, main pulmonary artery bulge and cardiomegaly (VHS = 11.5) were observed in radiographic findings. Ultrasonographic images showed both right and left ventricular dilation and turbulent flow between the descending aorta and the main pulmonary artery in color Doppler imaging. ECG showed left ventricular enlargement, SA block, and electrical alternant. Thoracotomy was performed through left fourth intercostal incision under isoflurane anesthesia. Patent ductus arteriosus was double ligated with 1-0 silk. Cough and dyspnea disappeared on 5 days after operation. Turbulent flow was not found in color doppler imaging of ultrasonography on 10 days after operation. Ten months later after the operation, syncope could not exist any more.

머리염색이 인체에 미치는 영향

윤형식,황성호,이현륭,김수호,박연석,권낙현,정호진,김동훈,노현주,홍성호,박병찬,이관,정해관 東國大學校醫學硏究所 2002 東國醫學 Vol.9 No.1

일상생활에서 모발염색은 흔히 접할 수 있는 미용의 한 종류로 특히 젊은층을 중심으로 폭발적으로 유행하고 있다. 염색을 위항 사용하는 약제는 표백제와 발색제 등 각종 화학약품이 사용되고 있으나 이로 인한 건강장해에 대한 연구는 그리 많지 않다. 저자들은 염색이 인체의 모발건강에 미치는 영향을 파악하기 위하여 염색과 관련된 주관적 증상과 모발의 변화에 대한 실험적 연구를 시행하였다. 동국대학교 경주 캠퍼스 재학생 80명을 대상으로 설문조사를 시행하여 염색 유 ·무 및 염색 후에 경험한 증상에 대해 설문 조사하였고, 의과대학 재학생 46명을 대상으로 피부 반응 테스트를 실시하였다. 또한 염색 전후의 모발 탄성도를 측정하였고 모발의 상태를 파악하기 위해 전자 현미경검사를 실시하였다. 설문조사 결과 염색 전에 비하여 염색 후 안구혼탁, 안구건조, 시력저하, 발진 및 접촉성 피부염, 모발손상, 모근손상 등의 증상을 더 많이 경험한다고 호소하였다(p<0.05). 모발손상과 모근손상은 헤어드라이어 사용 빈도에 따라 증가하는 것으로 조사되었다(p<0.05). 피부반응검사에서 가려움증이 가장 많은 증상이었으며 이는 여성보다는 남성에서 높은 것으로 조사되었다. 염색 전후의 모발장력은 염색 전 134.5±10.37g, 염색 128.0±30.69g, 염색 이틀 후 112.5±19.69g으로 나타났다. 염색 전후의 모발의 전자현미경 케라틴 층이 현저히 감소하고 모발이 가늘어지는 차이를 보였다. 염색은 모발손상, 모발 케라틴 손상 및 모근 손상, 발진 및 접촉성 피부반응, 안구혼탁, 안구건조, 시력 저하를 유발한다. 따라서 염색약으로 인한 손상에 대한 주의와 예방이 필요하다고 생각한다. 예방대책으로 염색 전 피부테스트를 통한 적합성 여부를 판단하는 것이 필요하며 가급적 염색을 피하는 것이 좋을 것이다. 염색약에 발암물질이 포함되어있다는 보고도 있어 염색 제조사의 철저한 실험과 염색 물질의 선별이 염색으로 인한 부작용을 최소화하는데 중요한 역할을 할 것이다. Hair coloring has became one of the most popular cosmetic activities to younger generations during last decade. However, there are few studies on the health effect of widespread use of chemical dyes. This study was conducted to study the effects of hair coloring dye on hair and other systems. We conducted a questionnaire survey of 80 persons in Kyongju campus, Dongguk University. We have done open patch skin test on 46 medical students. We also conducted scanning electron microscopy to examine the hair strength and structure before and after hair coloring process. Injury of hair and hair bulb, contact dermatitis, turbid eyes, xerophthalmia, and poor visual acuity were the main symptoms complained after hair coloring (p<0.05). Injury of hair and hair bulb were increased by frequency of hair-dryer use(p<0.05). In open patch test, pruritus was complanined by more than half of the subjects. Mean strength of hairs before and after hair coloring was as follows; 134.5 (SD 10.37)g before hair coloring, 128.0 (SD 30.69)g immediately after hair coloring, and 112.5 (SD 19.69)g after two days. The scanning electron microscopic findings of hair surface before and after hair coloring showed decreased keratin layer and thinning of the hair. Hair coloring induces injury to hair, its keratin layer, and hair bulb as well as contact dermatitis, turbid eyes, xerophthalmia, and poor visual acuity. Therefore, we think that precaution is needed in use of hair coloring dye. To prevent complications induced by hair coloring dye, it is necessary, especially to those with allergy or skin disorders, to perform skin test before action and avoid hair coloring whenever possible. Longterm health effects of hairdye should be studied and manufacturing companies should try to minimize complications induced by hair coloring dye.

중생 고품질 내병 다수성 벼 ‘영보(嶺寶)’

박노봉(No-Bong Park),김상열(Sang-Yeol Kim),여운상(Un-Sang Yeo),김정일(Jeong-Il Kim),이지윤(Ji-Yoon Lee),권오덕(Oh-Deog Kwon),박동수(Dong-Soo Park),이종희(Jong-Hee Lee),조준현(Jun-Hyun Cho),송유천(You-Cheon Song),오성환(Seong-Hwan Oh) 한국육종학회 2019 한국육종학회지 Vol.51 No.4

‘Yeongbo’ is a variety of japonica rice (Oryza sativa L.) with good eating quality, resistance to rice stripe virus, rice dwarf virus, and bacterial blight disease. It was developed by the rice breeding team of the Yeongdeok Branch, National Institute Crop Science, Rural Development Administration in 2014. This variety was derived from a cross between ‘Yeongdeog35’ with good eating quality and ‘Saekyehwa’ with good plant type in the 2002 summer season. A promising line selected through the pedigree breeding method, YR24269-1-2-1-2-3-3, was designated as ‘Yeongdeog57’ in 2011. After a local adaptability test at nine locations from 2012 to 2014, ‘Yeongdeog57’ was released under the name of ‘Yeongbo’ in 2014. ‘Yeongbo’ had a short culm length of 66 cm and medium growth duration. This variety was resistant to K1, K2, and K3 races of bacterial blight, rice stripe virus, and dwarf virus, and moderately resistant to leaf blast disease. ‘Yeongbo’ had translucent and clear milled rice kernel without white core and belly, and good eating quality according to a panel test. The yield potential of ‘Yeongbo’ in milled rice was approximately 5.75 MT/ha at an ordinary fertilizer level in the local adaptability test. This cultivar would be adaptable to middle plain area, south plain area, Yeongnam plain area, east costal area, and south mid-mountainous area. (Registration No.6804)

중년 비만 여성의 에어로빅스 트레이닝이 내장지방에 미치는 영향

박재현,윤미숙,박상갑,노금선,윤종관,권유찬 대한비만학회 2001 The Korean journal of obesity Vol.10 No.2

한국인 ADPKD 환자에서의 TGF-β1 Gene Leader Sequence 유전자 다형성의 분포 및 임상경과와의 연관성

오윤규(Yoon Kyu Oh),한진석(Jin Suk Han),이증건(Jung Geon Lee),안규리(Cu Rie Ahn),어현선(Hyun Seon Eo),노진주(Jin Ju No),김근화(Keun Hwa Kim),이은주(Eun Joo Lee),황영환(Yeong Hwan Hwang),황대연(Dae Yeon Hwang),이세한(Se Han Lee),이정은(J 대한신장학회 2002 Kidney Research and Clinical Practice Vol.21 No.1

목 적 : 상염색체우성다낭신(ADPKD) 환자에서 가계간·가계내의 임상양상의 심한 차이는 원인유전자 돌연변이 외에 modifying gene의 존재를 시사한다. 본 연구는 한국인 ADPKD 환자에서 TGF-β1 유전자 다형성의 분포와 고혈압, 신부전 등 임상상과의 연관성을 알아보고자 하였다. 방 법 : 정상 성인 47명과 ADPKD 환자 114명을 대상으로 TGF-β1 g ene leader sequence에 대한 PCR 시행한 후 제한효소 MspA 1I, Bg lI로 각각 처리하여 T 869C(Leu 10Pro)과 G915C(Arg25Pro)의 다형성을 보았다. 신부전, 고혈압 발생과의 연관성을 검정하였다. 결 과 : 각 유전자군의 비율은 Hardy -Weinberg 등식에 부합하였으며, TGF - β1의 BglI 처리결과는 125명 모두 GG형으로 서구인과 차이를 보였다(G : C=90 : 10). T GF - β1의 MspA1I 처리결과 정상인에서의 T : C allele의 빈도(56 : 44)는 서구인(65 : 35)과 차이를 보이지 않았으며, 총 PKD 환자군의 빈도(52 : 48)와도 통계적 차이를 보이지 않았다(p=0.670). PKD 환자군을 말기신부전 및 조기 고혈압 발생에 따라 나누었을 때 T : C allele 빈도의 차이는 없었다(p=0.571, p=0.252). 결 론 : 한국인 ADPKD 환자에서 TGF - β1 leader sequence 유전자 다형성과 임상경과 간에 유의한 관련은 없었고, 이는 싸이토카인의 유전적 차이보다는 물리적 요인 등 이차적인 원인에 의해 신조직 섬유화가 진행하는 것을 시사한다. Background : Two genetic loci, PKD1 and PKD2, have been identified as being responsible for ADPKD, and PKD1 is known to be associated with poor prognosis. However, the presence of intrafamilial clinical diversity suggests the presence of disease-modifying loci. Because the mechanism of renal failure in ADPKD includes cystic growth and tubulointerstitial atrophy and fibrosis, we studied the associations between two cytokine gene polymorphisms in the TGF-β1 gene, which are known to be related with chronic tubulointerstitial inflammation, and ADPKD progression in Korean patients. Methods : 47 normal controls and 114 individuals with ADPKD were genotyped by PCR-RFLP, and the TGF-β1 gene leader sequence of T 869C(Leu10-Pro) variant was compared with M spA 1I and G915C (Arg25Pro) with B glI. Statistic significances were determined using the Chi-square test. Results : The distribution of alleles for the T GF-β1 Leu10Pro polymorphism in ADPKD was : T 52%, C 48%, which w as similar to the Korean (56 : 44, p=0.670) and Western controls (65 : 35), and in addition, no differences were found between the CRF and the non-CRF groups (p=0.571) or the early hypertension and the normotension groups (p=0.252). T he distribution of alleles for the TGF-β1 Arg25Pro polymorphism was all GG type, which w as different from Western controls (90 : 10, p=0.000). Conclusion : Our results suggest that the polymorphism at Arg25Pro of TGF-β1 in Korean population has different allele distribution from Western, and the polymorphism at Leu10Pro of TGF-β1 has no association with the renal progression of Korean ADPKD patients.

Development of a semi-empirical model for forced convection film boiling on a sphere in water based on visual observations

Yoon, Seung Hyun,NO, Hee Cheon,Kim, Minju Elsevier 2018 INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER - Vol.127 No.3

<P><B>Abstract</B></P> <P>High-temperature film boiling in forced convection is dominant heat transfer regime after corium jet breakup in fuel-coolant interaction (FCI). Considering radiation contribution to heat transfer in a high superheat condition, we modified the Epstein-Hauser model by reflecting the radiation term on the energy balance at vapor-liquid interface. This correction resulted in an increase of convective heat transfer in the vapor film compared to the convective heat transfer from no correction. For the reference case, which is D<SUB>sphere</SUB> (sphere diameter) of 4 mm, ΔT<SUB>sub</SUB> (subcooling) of 40 K, and u (liquid velocity) of 1 m/s, the convective heat transfer from the correction showed 1.1–2.4 times higher than those from no correction at T<SUB>sphere</SUB> (sphere temperature) of 1000–3000 °C. High-temperature experiments were conducted for forced convection film boiling on spheres (kanthal-a1 and SS316L) at atmospheric pressure under the conditions for D<SUB>sphere</SUB> of 10 mm, ΔT<SUB>sat</SUB> (superheat) of 600–1200 K, ΔT<SUB>sub</SUB> of 20–70 K, and u of 0.5–1.3 m/s. The experimental results showed that the original Epstein-Hauser model does not well predict the dependencies on subcooling, superheat, and Reynolds number. Based on the visual observations, we developed the corrected Epstein-Hauser model with a new physical coefficient, which lies between 1 and 2. It showed the highest accuracy (10.99%) in terms of normalized root mean square deviation (NRMSD), compared to the original Epstein-Hauser model (61.92%) and Liu-Theofanous model (19.72%).</P> <P><B>Highlights</B></P> <P> <UL> <LI> We corrected Epstein-Hauser model by reflecting radiation on heat balance at vapor-liquid interface. </LI> <LI> High-temperature experiments for forced convection film boiling were conducted. </LI> <LI> Dependencies of Nu<SUB>exp</SUB>/Nu<SUB>corrected EH</SUB> on the wall superheat, Reynolds number and the subcooling were investigated. </LI> <LI> We suggested a physical coefficient C with the corrected Epstein-Hauser model based on visual observations. </LI> </UL> </P>

Inhibitory Effects of Corni Fructus on Testosterone-induced Benign Prostatic Hyperplasia in Rats

Hyun Hwangbo,Eun Ok Choi,Kyung-Il Kim,Son-Ho Yoon,Jung-Sub Jung,No-Jin Park,Ji-Suk Jeong,Jin-Woo Jeong,Cheol Park,Su Hyun Hong,Jae-Hun Cheong,Yung Hyun Choi 한국식품영양과학회 2017 한국식품영양과학회 학술대회발표집 Vol.2016 No.10

The Effect of Body Mass Index on Entrance Surface Air Kerma in Abdominal X-ray Radiography Using Automatic Exposure Control

No-Hyun Koo,Hee-Soo Yoon,Kwan-Woo Choi,Jong-Eun Lee,Jeong-Jin Kim 한국방사선학회 2018 한국방사선학회 논문지 Vol.12 No.5

본 연구는 자동노출제어 (AEC; Automatic Exposure Control)를 이용한 복부 일반 X선 검사에서 체질량지수 (BMI; Body Mass Index)가 입사표면공기커마 (ESAK; Entrance Surface Air Kerma)에 미치는 영향에 대해 알아보았다. 연구방법은 AEC를 이용하여 복부 일반 X선 검사를 시행 받은 321명을 대상으로 키, 몸무게, BMI와 ESAK의 관계 및 BMI범주 (Underweight, Normal, Overweight, Obese 1, Obese 2)에 따른 평균 ESAK값을 비교하였다. 연구의 결과 몸무게 (R2=0.777, p<.001)와 BMI (R2=0.835, p<.001)는 ESAK와 양의 상관관계가 있었던 반면, 키 (R2=0.075, p<.001)와 BMI는 뚜렷한 상관관계를 확인할 수 없었다. BMI범주에 대한 평균 ESAK는 통계적으로 유의한 차이를 보였으며, 사후분석을 통해 유의수준 0.05에 대해 5개의 부집단이 존재하여 모든 BMI범주 간 ESAK값의 차이가 있는 것을 알 수 있었다. 또한, 인접한 BMI간 ESAK값 증가폭이 Underweight에서 Obese 2로 갈수록 점차 늘어나 BMI가 증가할수록 피폭선량이 급격하게 증가되는 것을 알 수 있었다. 따라서 복부 일반 X선 검사에서 AEC를 사용할 경우 BMI가 증가함에 따라 과도한 선량이 조사될 수 있음을 인식하고 검사조건을 고정하여 촬영하는 등의 노력을 통한 선량저감화가 필요할 것으로 판단된다. The purpose of this study was to determine the effect of body mass index (BMI) on entrance surface air kerma (ESAK) in abdominal X-ray radiography using automatic exposure control (AEC). This study included 321 patients who underwent abdominal X-ray using AEC, and we correlated ESAK with height, weight, BMI and compared mean ESAK according to BMI grades (Underweight, Normal, Overweight, Obese 1, Obese 2). As a result, Weight (R2=0.777, p<.001) and BMI (R2=0.835, p<.001) were positively associated with ESAK, but no significant association was found between height (R2=0.075, p<.001) and ESAK. The mean ESAK with respect to BMI grades showed statistically significant difference and in the post-hoc analysis, the existence of 5 subgroups at the significance level of 0.05 indicated that there were differences in the ESAK in all BMI grades. Also, as the increment of ESAK between two neighboring BMI grades increases from Underweight to Obese 2, the exposure dose dramatically increased as the BMI increased. Thus, an excessive exposure dose due to increasing BMI when using AEC should be acknowledged and Efforts to reduce dose should be taken, such as: by fixing the exposure conditions.

외부 열화 요인이 CNT 혼입 시멘트계 복합체의 전기적 성능에 미치는 영향에 대한 개요

윤현노(Yoon, Hyun No),장대익(Jang, Dae Ik),이행기(Lee, Haeng Ki) 한국콘크리트학회 2020 한국콘크리트학회 학술대회 논문집 Vol.32 No.2