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      • KCI등재후보

        유아 신체발달과 체육활동에 대한 유아체육 강사의 인식 및 유아체육 지도현황

        안상춘,박혜경 이화여자대학교 사범대학 교육과학연구소 2004 교육과학연구 Vol.35 No.2

        국문초록누락 The purpose of present research is to offer the survey data on the expertise, the understanding of children's physical development and their physical activities, and the educational condition, of the instructors who teach physical education (PE) to young children in various educational institutions and other child-related facilities. 207 subjects of survey in a written form performed in this research include instructors belonging to 15 specialized institutions for teaching PE for young children located in Seoul and in Gyeonggi-do. 16 subjects of survey in an oral form (i.e., interviews) include 15 chiefs managing the specialized institutions for teaching PE for young children located in Seoul and Gyeonggi-do. The findings in this research are as follows: First, inspecting the 'expertise' of the instructors who teach PE to young children reveals that majority of the surveyed instructors majored in PE in institutions for higher education; only the half of the surveyed instructors have the qualifying license. Second, the survey on the understanding of children's physical development and their physical activities reveals that the surveyed instructors are well aware of activity progression with respect to children's physical development and teach appropriate physical activities accordingly. Third, the survey on educational conditions reveals that instructional curricula consist mainly of the area in self-testing through employing integrated apparatus while children prefer various games, It is also shown that the surveyed instructors teach proper basis physical activities with respect to children's physical development - easy to difficult activities according to children's age, and that the instructors' preferred apparatuses are mat and uni-bars for children's age 3, 4 and 5.

      • SCOPUSKCI등재
      • 파라캇에 의한 대뇌 피질 손상 : 증례 보고

        안미영,신동익,이형석,백신혜,이성현,이상수 충북대학교 의과대학 충북대학교 의학연구소 2010 忠北醫大學術誌 Vol.20 No.1

        Paraquat is widely used as a universal herbicide. Paraquat induces brain damage in case of fatal poisoning. It is well documented that paraquat exposure is associated with Parkinson's disease. However, many reports suggest paraquat is not selective for the dopaminergic nigro-strial system. Preferably, there are reports that cortical neurons were found to be more sensitive to paraquat. A39-year-old woman committed suicide by drinking 20 ml of a 20% solution of Paraquat. After 5 days, she had a convulsive seizure and lost consciousness. Brain MRI showed diffuse cerebral cortical edema of bilateral frontal and temporal lobes. She died 2 days after progressive pulmonary fibrosis. Here, we report a patient with paraquat induced cortical lesion. 파라캇은 세계적으로 널리 쓰이는 제초제이다. 파라캇은 중독되었을 경우 뇌손상을 일으키기도 한다. 파라캇과 파킨슨병과의 관련성은 비교적 잘 알려져 있다. 하지만, 파라캇이 도파민 줄무늬흑체 계통(dopaminergic nifro-striatal system)에 선택적이지 않다는 많은 보고들이 있다. 오히려, 대뇌피질이 파라캇 중독에 더욱 민감하다는 일부 보고들도 있다. 39세 여자환자가 자살할 목적으로 20% 농도의 파라캇 20 ml를 마시고 본원에 내원하였다. 환자는 입원 5일째 갑자기 전신 발작 증상과 함께 의식 저하 소견을 보였다. 다음날 시행한 뇌자기공명영상 촬영상 양쪽 측두엽과 전두엽에 대칭성 세포 도겅부종 소견을 보이고 있었다. 그녀는 2일 후 폐섬유화증에 의한 호흡부전으로 사망하였다. 저자들은 파라캇 중독 환자에서 대뇌 피질 손상을 확인한 1예를 경험하였기에 보고하는 바이다.

      • SCOPUSKCI등재
      • 부산시 도심일대의 지가형성요인분석에 관한 연구

        안혜진,이성호 釜山大學校 都市問題硏究所 2002 都市硏究報 Vol.12 No.-

        The purpose of this study is to analyze impacts of the various factors influencing land prices in terms of accessibility, institutional characteristics of land and physical characteristics of land in the central area of Pusan. For the purpose, this study is carried out by using the hedonic price model which represents and implicit value of a certain property based on its interior value-characteristics. The analysis of this study consists of three parts: the spatial distribution characteristics of land prices in the central area of Pusan, the spatial distribution characteristics of land prices by zoning in the central area of Pusan and the spatial distribution characteristics of land prices by Gwang-Bok Dong's sphere of influence and Pu-Jeon Dong's sphere of influence in the central area of Pusan.

      • 사람-사람 하이브리도마의 생산을 위한 fusion partner cell의 개발

        안지영,김혜원,서동상 성균관대학교 생명과학자원연구소 1995 生命資源科學硏究 Vol.2 No.1

        This study was performed to establish human hybridmyeloma cell lines as fusion partner cells for producing human-human hybridoma. Human myeloma, SKO-007(J3), and human cervix epitheloid carcinoma cell line, HeLa MR, were fused by using with 50% PEG, and cultured in RPMI 1640 medium containing 15% FBS. Hybrids of SKO-007(J3) and HeLa MR were selected in RPMI 1640 media containing 6-thioguanine(6-TG ; gradually increasing concentration from 10 ㎍/ml to 20 ㎍/ml, and then gradually decreasing to 10 ㎍/ml) for 6 weeks. 6-TG resistant cells were collected and cloned by limiting dilution method. The fused myelomas with HeLa MR grew more rapidly than the fused cells with a small number of HeLa MR. Their doubling time was 72 hours.

      • KCI등재

        자일리톨 섭취에 따른 Streptococcus mutans의 글루칸 생성관련 유전자 발현 억제효과

        김지혜,이영은,안상헌,최연희,남순현,송근배 大韓小兒齒科學會 2009 大韓小兒齒科學會誌 Vol.36 No.4

        본 연구에서는 장기적인 자일리톨의 섭취가 Streptococcus mutans의 대표적인 독성인자 중 하나인 글루칸 생성에 미치는 영향을 알아보기 위하여 글루칸 합성효소인 glucosyltansferase의 mRNA 발현을 실시간 역전사 중합효소 연쇄반응을 통해 평가하여 다음과 같은 결과를 얻었다. 1. 24개월 동안 자일리톨껌을 섭취한 군에서 타액 내 Streptococcus mutans의 colony 수는 통계적으로 유의하게 감소하였다(p<0.05). 2. 비수용성 글루칸 합성에 관여하는 유전자인 gtfB, gtfC의 발현은 자일리톨껌을 섭취한 군에서 시간이 지남에 따라 유의 하게 감소하였다(p<0.05). 특히 gtfB의 발현은 12개월과 24개월째 대조군에 비하여 통계적으로 유의하게 낮았고, gtfC의 발현은 24개월째 대조군에 비하여 통계적으로 유의하게 낮았다(p<0.05). 3. 수용성 글루칸 합성에 관여하는 유전자인 gtfD의 발현 역시 자일리톨껌을 섭취한 군에서 시간이 지남에 따라 유의하게 감소하였다(p<0.05). 또한 gtfD의 발현은 12개월과 24개월째 대조군에 비하여 통계적으로 유의하게 낮았다(p<0.05). 이상의 결과들을 종합해 보았을 때, 자일리톨의 섭취는 구강 내 Streptococcus mutans의 글루칸 합성 관련 유전자들의 발현을 억제시킴으로써 Streptococcus mutans의 수적인 감소를 가져오는 것으로 생각된다. Xylitol has the ability to reduce the adherence of Streptococcus mutans(S. mutans), which can make it easier to remove plaque, decrease acid production and inhibit dental caries. There are few reports on the effects of xylitol on the expression of the virulence related genes in S. mutans. This study examined the inhibitory effect of chewing gum containing xylitol on glucan synthesis related gene expression of S. mutans. Participants were voluntarily recruited for a women's oral health prevention program, classified into two groups(a control and a xylitol group), and then followed for 2 years. Twenty salivary samples were randomly selected from each group. Colony count and real-time reverse transcription polymerase chain reaction were used to analyze the characteristics of S. mutans. The following results were obtained: The S. mutans counts decreased steadily in the xylitol group over the study period(p<0.05). The expression of the virulence related genes (gtfB, gtfC and gtfD) was significantly lower in the xylitol group than in the control groups (p<0.05). In conclusion, these results suggest that chewing xylitol gum for a long period of time may reduce the expression of the genes associated with S. mutans virulence, which can result in a decrease growth of S. mutans colonies as a result.

      • 한의진단명과 진단요건의 표준화 연구 II (표준화 실례) : 2차년도 연구결과 중간 보고

        양기상,최선미,최승훈,안규석,박경모,박종현,김성우,신승호,정우열,전병훈,고현,김정범,신상우,김성훈,김동희,권영규,엄현섭,장혜옥 한국한의학연구원 1996 한국한의학연구원논문집 Vol.2 No.1

        The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the second year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows; - differential diagnosis according to condition of body fluid, differentiation of syndromes according to the state of qi and blood, differential diagnosis according to relative excessiveness or deficiency of yin and yang(氣血陰陽津液辨證) - differentiation of diseases according to pathological changes of the viscera and their interrelation - analyzing and differentiating of febrile diseases in accordance with the theory of the six channels(傷寒辨證) The individual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name(異名), notion of diagnosis pattern, index of differentiation of symptoms and signs(辨證指標), the main point of diagnosis, analysis of diagnosis pattern(證候分析), discrimination of diagnosis pattern(證候鑑別), a way of curing a diseases(治法), prescription(處方), herb in common use(常用藥物), diseases appearing the diagnosis pattern(常見疾病), documents(文獻調査). This study was carried out on the basis of the Chinese documents and references.

      • KCI등재

        공동사회모임에서 환자와 치료자가 인식한 치료요인

        박혜영,배안,신성웅,윤우상 大韓神經精神醫學會 1997 신경정신의학 Vol.36 No.3

        본 연구에서 저자들은 공동사회모임에 참여한 환자와 지료자의 공동사회모임에 대한 반응을 알아보고, 일종의 집단정신치료로서 공동사회모임의 치료적 효과를 Yalon의 Q-sort 단축형 척도를 적용하여 평가하므로써 공도사회모임의 문제점을 진단, 보완하고, 집단치료로서의 치료적 기능을 활성화하고자 하였다. 평가대상이 된 10차례의 공동사회모임은 비교적 치료공동체가 부침기에 해당하는 기간에 열렸으며, 매회당 환자군 26.7명(±2.95)과 치료자군 8.5명(±1.43)이 참가했다. 그 결과 환자와 치료자 모두 공동사회모임을 긍정직으로 평가하였으며, 도움이 된 항목에 대하여 환자는 '서로간의 이해와 사랑', '자신에 대하 깨달음'이라고 답하였고, 치료자는 '솔직한 자기표현'과 '대화'가 도움이 되었다고 하였다. 또한 공도사회모임의 집단치료 치료요인의 모든 항목에서 치료자군에 비하여 환자군이 더 치료적이라고 평가하였으며, 특히 '보편성', '지침', '카타르시르'를 제외한 9개의 항목에서 통계적으로 유의한 차이가 있었다. 공동사회모임에서 활성화된 집단치료 치료요인으로서 환자와 치료자는 공통적으로 '실존적 인자'와 '보편성'이라고 압했으며, '외면적 대인간 학습'을 비활성화된 치료요인으로 평가하였다. This research was conducted to investigate the responses of the patients and the therapists who attend the community meeting, to evaluate the therapeutic effects fo community meeting as a group psychotherapy by applying short form scale of Yalom's Q-sort, to diagnose and complement the problems of the community meeting and to aim at activating the therapeutic function as the group psychotherapy. The community meeting was held by 10 times during the stage of oscillation of the community and 26.7 patients group(±2.95) and 8.5 therapists group(±1.43) attended the every meeting. Consequently, both patients group and therapists group evaluate the community meeting as positive, and on the item which is helpful to them, while patient group responds it is 'mutual understanding and love' and 'self-understanding', therapist group does it is 'frank self-expression' and 'conversation'. On all items of group psychotherapy facors in the community meeting, the patients group evaluates it is more therapeutic in comparison with the therapists group, especially there is a significant difference in nine items such as 'altruism', 'group cohesiveness', 'interpersonal input', 'interpersonal output', 'identification', 'instillation of hope', 'family reenactment', 'self-understanding' and 'existential awareness'. In addition, on the therapeutic factor which is activated group psychotherapy factor in the community meeting, both patients and therapists respond that it is 'existential awareness' and 'universality', and they evaluate 'interpersonal output' as an non-activated therapeutic factor.

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