Ho-166 부착풍선도자를 이용한 방사선 조사의 돼지 관상동맥 스텐트 재협착 예방 효과

김원 ( Kim Won ),정명호 ( Jeong Myeong Ho ),박옥영 ( Park Og Yeong ),정우곤 ( Jeong U Gon ),박우석 ( Park U Seog ),김주한 ( Kim Ju Han ),안영근 ( An Yeong Geun ),조정관 ( Jo Jeong Gwan ),박종춘 ( Park Jong Chun ),강정채 ( Kang Je 한국지질동맥경화학회 ( 구 한국지질학회 ) 2002 韓國脂質學會誌 Vol.12 No.1

배경 : 국내에서 개발된 방사선 동위원소 Holmium-166 (166Ho)은 주로 베타선을 방출하며, 166Ho을 부착한 풍선도자를 이용하여 돼지 관상동맥 재협착 모형에서 풍선확장술 후 신생내막 증식을 전신적 부작용 없이 안전하고 효과적으로 억제하였음을 보고한 바 있다. 본 연구에서는 돼지 관상동맥 스텐트 재협착 모형에서 스텐트 시술 후 신생내막 증식에 의한 재협착 병변을 166Ho 부착 풍선도자를 이용하여 치료하여 그 효과를 관찰하고자 하였다. 방법

데이터 웨어하우징의 구축과 발전동향

주상호,이종호 公州大學校工科大學生産技術硏究所 1998 論文集 Vol.6 No.-

Data Warehousing is a data set of subject-orientation, integration, time variancy, nonvolatility to support decision making. Nowadays, information technology is changing past OLTP environment into OLAP environment. And DW is most suitable environment support decision-making for competitive advantages in management activities. So, to have a higher competitiveness advantages, in case of building DW, it is very important to look for the proper system building technique after the integrated review and analysis considering the purpose and the amount of data, etc.

발포폴리스티렌비드를 사용한 경량콘크리트의 역학적 특성에 관한 실험적 연구

주재금,이종찬,오세출,유택동,정광량,서치호 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1(구조계)

The purpose of this study is to obtain basic data on the properties of the lightweight concrete within expanded polystyrene beads for various applications in the field. Inquiring into the change of the properties as altering cement matrix mixture and the capacity mixture ratio of expanded polystyrene beads, the mixture plane of this study is set up as W/C is fixed 50%, expanded polystyrene beads is increased 10% from 0% to 80% per 1m³ and the ratio of cement:sand in the cement matrix is 1:0, 1:0.5, 1:1. The results of this study are as follow. The slump as changing the mixture ratio of expanded polystyrene beads decrease smoothly until mixture ratio 50% but decrease rapidly being in excess of 50%. The density decrease regularly as the mixture ratio of expanded polystyrene beads increase but the ratio of strength decrease. The difference of cement matrix. The strength of cement matrix having more sand mixture ratio relatively decrease rapidly as increasing the mixture ratio of expanded polystyrene beads. It is judged decreased strength phenomenon as the quantity of coherent material created in the mixture decrease rapidly.

과학 학습 부진아 지도로서의 중재반응모형(RTI)의 적용 효과

주혜련,박종호 이화여자대학교 사범대학 교과교육연구소 2013 교과교육학연구 Vol.17 No.4

This study attempted to demonstrate the effect of Response to Intervention(RTI) as a teaching methodology for underachievers in science. The participants were fifth-grade students, and the intervention program involved the science textbook section 'The speed of an object'. In the first stage of the intervention, the subject matter was taught generally over a period of three weeks. The researcher conducted subgroup teaching using the direct method of teaching in the second stage of the intervention for eight weeks. This study consisted of three stages: the first stage of the intervention involved selecting underachievers in science and determining their baseline(the bottom 15%), the second provided sixteen thirty-minute sessions, twice a week over eight weeks. In the first stage of the RTI program, the researcher selected eleven underachievers in a fifth-grade science class for an experimental group. In the second stage, interventions were provided to them based on the Direct Instruction(DI) method. During the interventions, three achievement tests and ten curriculum-based assessments were conducted. The major research findings were as follows: first, the interventions based on the DI approach had positive effects on the underachievers. The science underachievers showed a higher achievement level than the general students when a sincere attitude was indicated. Second, the RTI program had positive effects on some of the science underachievers; although three of the eleven participants in the second stage showed no significant change. Third, this study suggests that underachieving in mathematics and science is closely related; science underachievers in the second stage were all underachievers in mathematics, too. RTI has not been applied to mathematics classes; but, based on the results of this study. RTI in science classes should be actively carried out in the future; it could contribute to the relief and determination of science underachievers. 현대 과학교육은 ‘모든 이를 위한 과학’을 지향하고 있다. 과학적 인재를 양성하는데 주력하는 것이 아니라 모든 이에게 과학적 소양을 함양시킬 수 있는 과학교육에 집중하는 것이다. 초등교육은 더욱 그러하다. 이에 본 연구는 중재 반응(Response to Intervention, RTI)을 적용하여 과학 학습부진 아동을지도하여 구제하는 데 효과가 있는지 입증하기 위해 실시되었다. 초등학교 5학년 아동을 대상으로 하였으며 5학년 2학기 3단원 ‘물체의 속력’단원으로 중재 프로그램을 구성하였다. 중재 1단계에서는 3주에 걸쳐 과학 전담 교사가 일반 교수를 실시하였고, 중재 2단계는 8주간연구자가 직접 교수법을 활용한 소집단 교수를 실시하였다. 1단계에서 학업성취도 검사 2회, 교육과정 중심 평가는 4회를 실시하여 두 검사 점수의 합이 하위 15%를 나타내는 15명을 과학 학습부진 아동으로 선별하여 그중 본인의 동의를 얻은 11명을 2단계 연구를 실시하였고, 2단계에서는 총3회의 학업성취도 검사와 총 10회의 교육과정 중심 평가를 실시하여 중재 반응의 효과를 분석하였다. 그 결과 2단계 중재로 과학 학습부진 아동으로 선별된 11명의 아동 중 8명이 일반 아동을 뛰어넘은 점수를 획득하였다. 따라서 과학 학습부진 아동이라 할지라도 중재 반응의 2단계소집단 교수에 성실히 임한 부진 아동은 일반 아동과 같은 학업성취도를 보일 수 있음을 확인하였고, 구제되지 못한 나머지 3명의 아동은 동일한 시간 동안 동일한 중재를 적용했음에도 불구하고 반응하지 않았으므로 과학 학습부진 아동이라고 판별할 수 있었다. 또한 2단계에서 반응을 보이지 않아 과학 학습부진 아동으로 판별된 아동이 모두 수학기초 학습 부진이었던 것으로 나타나 수학기초 학습 부진과 과학 학습 부진은 관련성을 가지고 있음을 볼 수 있었다. 이러한 연구결과를 바탕으로 이제껏 수학에서만 다루어지던 틀을 깨고 앞으로는 과학에서도 중재 반응을 적용한 중재 프로그램을 통하여 과학 학습부진 아동의 구제와 판별에 기여할 것으로 보인다.

바닥재 처리로 인한 수송 트레일러의 수직진동 감쇠 효과

이홍주,홍종호,김성엽 안성산업대학교 2002 論文集 Vol.34 No.-

This study was aimed to prevent the quality loss of agricultural products, which could be occurred by the vibrations of transporting trailer. The vibration absorption effect was measured and analyzed by mounting the polystyrene material on the bottom of trailer. The transporting trailer was tested with being mounted by the pear boxes up to fourth floor. The results of this study could be summarized as follows: 1. At low engine speed of 500rpm, the average vertical vibration level of the first floor boxes (lowest boxes) was reduced to almost half of the non-mounting system. And, at the fourth floor boxes (highest boxes), the vibration absorption effect was higher as about 10 times compared with the non-mounting system. 2. At standard engine speed of 1,000rpm, the average vertical vibration level of the first floor boxes was almost same as 0.005㎨ and 0.006㎨ respectively, but at the fourth floor boxes, the average vertical vibration was reduced to almost 60% of the non-mounting system.

地震波를 받는 基礎-地盤 相互作用계에서의 波消散 效課

金宗周,孫榮浩,崔鎭旭,崔光圭 東亞大學校 海洋資源硏究所 1992 硏究論文集 Vol.5 No.2

In this study , the dynamic analysis procedure of foundation -soil interaction system subjected to seisemic wave is presented . The foundation is placed on a linear elastic , isotropic and homogeneous half space representing the soil medium. The boundary element model of half space and the finit element model of foundtion are coupled together by enforcing compatibility condition of displacements and equilibrium condition of traction on the contact surface. The acuuracy of the proposed method si vertified throough the conparison studies with results reported method is that it provides directly the transient response unlike the frequency domain techniques.

케미컬오일을 이용한 ERF 연마 특성

윤종호,이재종,이응숙,이동주,김영호 한국공작기계학회 2004 한국공작기계학회 춘계학술대회논문집 Vol.2004 No.-

Electro-rheological fluid is recently used for the micro polishing of 3-dimensional micro-aspherical lens. It's also used for polishing small area defects on the wide flat wafer. Since ER fluid shows a behavior of viscosity changing under certain electric fields, micro polishing efficiency may be enhanced for certain cases. In this paper, a perfluorinated carbonyl fluoride oil based ER fluids was used to improve surface polishing rate and submicron-scale accuracy. As the polishing electrodes, micro size cylindrical tools had been used for maximizing the electric field. An experimental device, which was applied for micro polishing a number of wafers of 4 inches in size and other workpieces, was made on a precision polishing system. It consisted of a steel electrode, a wafer fixture, 10mA current and DC 5kV power supply unit, and a controller unit. From the Experiments, the ER fluid is applicable for micro polishing of small parts.

지리산 왕등재 습지의 지표수 수질 및 토양 환경조사

김종오,이창호,지인주 경상대학교 환경보전연구소 2001 環境保全硏究所報 Vol.9 No.-

The this study was performed to survey the characteristics of surface water and soil in Wangdungjae wetland located at Chiri-Mountain. The results of survey summarized as follows; 1. The physico-chemical characteristics of surface water such as pH, temperature, and DO were in the range of 6.02-6.39, 13.5-24.3℃, and 3.81-9.97 ㎎/L, respectively. Also, the organic concentration such as BOD and COD were in the range of 1.3-1.61 ㎎/L and 3.55-0.07 ㎎/L, respectively. The water quality of five different sampling sites showed the similar characteristics. 2. The physico-chemical characteristics of soil showed the different properties with the soil sampling depth. According to increasing sampling depth, cation exchange capacity (CEC) and electric conductivity (EC) increased but pH decreased.

VDT작업별 정신사회적 스트레스와 근골격계 장애에 관한 연구

백남종,강종두,주영수,배인근,권호장,박종만,조수헌,김돈규,김재용,최홍렬 大韓産業醫學會 1998 대한직업환경의학회지 Vol.10 No.4

It has been hypothesized that jobs that have both high psychological demands and low decision latitude("job strain") can lead to musculoskeletal disorder. The objective of this study was to test whether job strain was correlated with the presence of work-related musculoskeletal disorder, especially myofascial pain syndrome(MPS). Information on demographic factors, confounders such as household load and taking care of children or not, and scores for decision latitude, job demand, and social support was obtained by self-administered questionnaire, which had been developed in Korean language, by adopting NIOSH instrument and Extended Karasek Model(16 items). All subjects were also examined by rehabilitation medicine specialists for musculoskeletal disorders. Subjects(n=370) could be categorized into 4 groups, these were, housewives(n=89), shipyard CAD workers(n=89), general female workers(n=79; nurses, insurance counselors, public officials, clerks, etc), and telephone directory assistance operators(n=113). Results from univariate analyses indicated that all demographic factors, all confounders, scores for decision latitude and social support were not associated with the risk of musculoskeletal disorder. However, score for job demand was higher in musculoskeletal disorder cases than others. In subgroup analysis, this association was convinced again, in telephone directory assistance operators. Job strain model showed that the group of telephone directory assistance operators was high-stain group, and OR of musculo skeletal disorder was 2.446(95% C. I. : 1.174, 5.096), when comparing this with the low strain group. In conclusion, job strain is a risk factor for work-related musculoskeletal disorder.

초기계태에서 valproic acid에 의한 신경관 기형 : 입체현미경적 관찰

김동호,조무연,정유남,최영주,이종선,민경수,이무섭 충북대학교 의학연구소 2000 忠北醫大學術誌 Vol.10 No.1

연구목적 ' 항경련제인 valproic acid가 초기계태의 신경관 형성에 영향을 주는 기형유발에 대해 입체현미경하에서 관찰하였다 연구재 료 및 방법 : 백색의 Leghorn의 신선한 수정란을 30-35시간 동안 배양하여 Hamburger & Hamilton 기 5-10기의 초기 계태를 천공 필터를 이용하여 분리하여 6-30시간 동안 CO2 세포 배양기에서 배양하였고 무작위로 대조군과 실험군을 분류하였다. 실험군은 valproic acid 의 RPMI culture media 의 농도에 따라 100 ㎍/㎖, 200 ㎍/㎖, 500 ㎍/㎖, 1000 ㎍/㎖ 네가지 군으로 분리하였다. 각각의 대조군과 valproic acid를 처치한 실험군에서 입체 현미경하에서 초기계태의 신경관 형성의 형태학적인 특징과 기형형성의 빈도를 비교하였다. 결과: valproic acid가 없는 RPMI media에서 배양된 대조군은 24개의 계태는 22(91.7%)개는 정상으로 자랐으며 2(8.3%)개는 비정상으로 자랐다 이에 반하여 valproic acid가 처치된 RPMI media에서 배양된 72개의 계태는 42(58.3%)개가 비정상으로 자랐다. 주로 확인된 이상 형태는 신경주름의 변형. 신경관 폐쇄부전, 체절의 장애 및 발육 정지 등 이었다. 계태의 기형 형성은 valproic acid의 농도에 비례하여 증가하였다. valproic acrid 의 농도가 100 ㎍/㎖인 경우 18개 계태 중 2(11.1%)개에서 경미한 신경관 기형이 나타났으며 200 ㎍/㎖인 경우 18개 계태 중 11(61,1%)개는 정상, 7(38.9%)개는 명백한 신경관 기형이 나타났으며 500 ㎍/㎖인 경우 18개의 계태 중 5(27.8%)개는 정상. 13(72.2%)개는 명백한 신경관 기형을 나타냈다. 1000 ㎍/㎖인 경우 18(100%)개 모두 심한 신경관 기형이 나타났다. 결론: valproic acid는 초기계태에서 신경관 기형을 유발 했는데 저농도에서는 일부 경미한 신경관 이상을 보였고 고농도에서는 대부분 심한 신경관 손상을 동반하고 성장 속도가 둔화되어 약 용량의 증가에 따라 기형이 증가되는 dose-dependent manner 로 그 영향이 나타났다. Purpose : The teratogeruc effects of valproic acid widely used as anticonvulsant on the neurulation of the explanted eraly chick embryos were observed by the stereoscope. Materials and Methods: Fresh fertilized white leghorn hen eggs were incubated for 30-35 hours in an e99 incubator. The Hamburger and Hamilton stage 5-10 chick embryos were explanted using the punched-out filter paper explantation technique and cultured in the CO2 cell culture incubator for 6-30 hours. They were randomly divided into a control group and an experimental group. The experimental group was divided into four subgroups according to the valproic acid concentrations of 100 ㎍/㎖, 200 ㎍/㎖, 500 ㎍/㎖, 1000 ㎍/㎖ with which the RPMI culture media were treated. The morphological characteristics and the incidences of teratogenic effects on the neurulation of early chick embryos in the control and experimental groups were compared with each other using the stereomicroscope. Results : Of the 24 chick embryos cultured in the RPMI media without valproic acrid, 22 embryos(91.7%) developed normally, and 2 embryos (8.3%) developed abnormally, in contrast, among 72 embryos cultured in the valproic acrid-treated media, 42 embryos(58.3%) developed abnormally. The frequent anomalous features were deformities of the neural folds, failure of neural tube closure, derangement of somites, and developmental arrest. Of 18 embryos cultured in the media treated each with 100㎍/㎖ of valproic acid, 2 embryos(11.1%) showed mild abnormality of neural tube defect on stereoscopic examination. Of 18 embryos cultured 7l the media treated each with 200㎍/㎖ of valproic acid, 11 embryos(61.1%) developed normally for 20 hours and 7 embryos (38.9%) showed definite neural tube defect. Of 18 embryos cultured in the media 7reated each with 500㎍/㎖ of vaIprolc acid, 5 embryos(27.8%) developed normally (or 20 hours and 13 embryos (72.2% ) showed definite neural tube defect. Of 18 embryos cultured in the media treated each with 1000㎍/㎖ of valproic acid, 1 embryo developed normally for 4 hours but all embryos (100%) showed severe neural tube defect on whole brain after 8 hours of culture. Conclusion : Valproic acid induced mild neural tube defects in low concentration and in high concentration of valproic acid, most chick embryos developed slowly and showed severe neral tube defects. The frequency and severity of abnormal embryos ulcreased in dose-dependent manner.