서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

황금(黃芩)의 4-VO로 유발한 흰쥐뇌허혈에 대한 신경방어효과

李秉哲,林康鉉,金榮玉,金善礪,安德均,朴虎君,金護哲 대한본초학회 1999 大韓本草學會誌 Vol.14 No.2

Scutellariae Radix(SR), the root of Scutellaria baicalensis G_EORGI, whose property, flavour and channel tropism is bitter in flavour, cold in property(寒), acting on the lung, gallbladder, stomach and large intestine channels(歸?,?,?,大??), has the effects of clearing away heat and dampness(淸熱??), purging fire, detoxicating(?火解?), stopping bleeding(止血) and preventing miscarriage(安?). This drug is one of the popular drugs in traditional Korean medicine, which has been used to antipyretic, antibacterial, antitoxic and antihypersensitive effects. So this study was planned to check the neuroprotective effect of SR on the global ischemia induced by 4-vessel occlusion in Wister rats. and SR extract was lyophilized after extraction with 70% methanol. We induced 4-vessel occlusion for 10 minutes and reperfused again. The number of CA1 pyramidal neurons were counted after 7 days of reperfusion under the cresyl violet staining. The result obtained that in 4-VO ischemia, SR showed significantly neuroprotective effects(1,000 and 500 ㎎/㎏ of SR extracts, p<0.05) compared with control group. Each neuroprotective ratio was about 27.4 %, 23.2 % respectively. Consequently, Scutellariae Radix has neuroprotective effects on the global ischemia induced by 4-vessel occlusion in Wistar rats.

콘크리트가 凍害를 받은 境遇에 關한 硏究

金鐘守,陳鎬均 釜山工業大學校 1994 論文集 Vol.36 No.-

The concrete strength is affected by frost damage in afew times after placing concrete in the forms at -2˚∼5˚ degrees. As it takes measures heating, warm curing for a few days in its being frozen, it can improve the concrete strength and restrain the frost damage of concrete. In this study, in comparison with the temperature of freezing, the continuous time of freezing and the heating, moist curing after feezing indicated respectively different values of compressive strength and elasticity modulus. Through this paper, the established theories and experiments about the influence of frost damage on concrete have been proved.

ESPI를 이용한 복합재료 구조물의 결함 검출

김경석,정성균,강진식,장호섭 한국비파괴검사학회 2001 한국비파괴검사학회지 Vol.21 No.3

본 논문에서는 ESPI 시스템을 이용하여 복합재료 구조물의 인위, 자연 결함을 검출하였다. 복합재료 구조물에서의 ESPI의 적용성을 알아보기 위해 복합재료 적층판 시험편, 하니컴 구조물 시험편, 접착조인트 시험편을 사용하였다. 결함을 검출하기 위해 시편의 표면변형을 쉽게 발생시킬 수 있는 열하중법을 선택하였다. 실험경과는 ESPI를 이용하여 복합재료 구조물의 결함을 쉽게 검출할 수 있고, 다른 여러 복합재료 구조물의 결함의 검출에도 적용할 수 있음을 확인하였다. In this paper, artificial and real defects(delamination and debond) in composite structures were detected by using ESPI system. There types of specimens, that is, composite laminates, honeycomb structures, and adhesive joints, were used to study the applicability of ESPI to composite structures. To detect defects in specimens, we selected thermal loading method that can easily induce the surface deformation of specimen. Experimental results show that defects in composite structures could be easily detected by ESPI. Moreover, it shows that ESPI could be usefully applied to the detection of defects of defects in various composite structures.

掌葉大黃이 白鼠의 胸部大動脈 血管弛緩에 미치는 影響

김형환,구본식,박수연,안덕균,최호영,박성규 대한본초학회 2002 大韓本草學會誌 Vol.17 No.2

Objectives : We have examined the relaxational response to the water extract of Rheum palmatum L. in isolated thoracic aorta from sprague dawley (SD) rat in the presence and absence of endothelium. Methods : Rat thoracic aorta was investigated in vessel segments suspended for isometric tension recording by polygraph. Responses to Rhizoma Rhei were investigated in vessels precontracted with 5-hydroxytryptamine. We found that the thoracic aorta segments responded to the water extract of Rheum palmatum L. (ERP) with a dose-dependent vasorelaxation. Results : We found that 1. The thoracic aorta segments responded to ERP with a dose-dependent vasodilation. 2. The 5-HT induced contraction at 10^-4M were inhibited by 85.8% after addition of the 0.1 g/mL water extract of ERP. 3. The 5-HT induced contraction at 10^-4M with and without endothelium were inhibited by 86.4% and 85.8% after addition of the 0.1g/mL ERP. 4. After pre-treatment of the thoracic aorta with 10^-4M N^G-monomethyl-L-arginine (L-NMMA), inducible nitric oxide synthase inhibitor, the vessels has not response to the contraction. Conclusion : In conclusion, ERP induced relaxation in the isolated rat thoracic aorta were composed of dose-dependent relaxation and it has potent vasodilation.

현 단계 스페인 과거사 청산의 동향과 전망

김현균,임호준 서울대학교 스페인중남미연구소 2006 이베로아메리카硏究 Vol.17 No.-

Este trabajo tiene por objeto revisar las últimas tendencias de la liquidación del pasado para curar la trauma histórica en España. La transición española se realizó dejando a la sombra importantes parcelas de la memoria que poco a poco buscan salir a la luz. Asi que en el sector público últimamente han aparecido varias intenciones de recuperar esos fragmentos de la memoria. Estas iniciativas empujaron que el Gobierno procediera a abrir oficialmente la caja de memoria y investigara algunas medidas necesarias para una reconciliación final. El proyecto de la Ley que duró un año y medio en redacción y al fin vio la luz en pasado julio es la colección de estas medidas. La norma, de 25 artículos, establece por primera vez un mecanismo para la rehabilitación oficial, en nombre de Estado, de todas las víctimas de la Guerra Civil y la represión franquista. Se trata del texto con que el Gobierno intenta evitar los posibles conflictos sociales reduciendo el nivel al mínimo. A pesar de la insatisfacción de ambos lados ideológicos, sin duda alguna es un paso muy importante para construir un futuro de convivencia democrática y pacífica en la sociedad española.

천마 (天麻)의 4-Vessel Occlusion으로 유발한 흰쥐 전뇌허혈에 대한 신경보호 효과

金護哲,安德均 대한본초학회 1999 大韓本草學會誌 Vol.14 No.1

Gastrodiae Rhizoma(GR), the rhizoma of Gastrodia elata B₁, has been used for the effect of calming the liver(平?) in Traditional Korean Medicine. We hypothesized this effect of calming the liver has relations with the effects of curing stroke. So, this study was planned to check the neuroprotective effect of GR on the global ischemia induced by 4-vessel occlusion in Wister rats. GR extract was lyophilized with ethanol after reflux extraction with water. We induced 4-vessel occlusion for 10 minutes and reperfused again. The number of CA₁ pyramidal neruons were counted after 7 days of reperfusion under the cresyl violet staining. The result showed significant protective effects of samples compared with control group which was administrated with normal saline in the intraperitoneal injection of 1200㎎/㎏ and 600㎎/㎏ of Gastrodiae Rhizoma extracts at 0, 2 and 6 hours after inducing cerebral ischemia. We also observed the same results when it was injected at 30 minutes before inducing ischemia. The extract of GR did not lower body temperature at these dosages. Further study will be needed to separate the active ingredients of GR and study molecular biological mechanism for developing neuroprotective drug.

발산풍열약(發散風熱藥)의 항고혈압작용에 관한 연구

金護哲,朴珠瑛,安德均 대한본초학회 1999 大韓本草學會誌 Vol.14 No.1

Balsanpungyeolyak, Expelling Pathogenic Wind-Heat Drug, have been used to treat the symptoms such as fever, headache, neck stiffness and skin disturbance which are commonly shown in systemic fever disease like influenza. We thought that the symptoms from the actions of wind and heat in Traditional Korean Medicine are similar to the ones of hypertensive patients in clinic. We chose five drugs among expelling pathogenic wind-heat drugs, Puerariae Radix, Chrysanthemi Flos, Menthae Herba, Mori Folium, and Arctii Fructus, to investigate their antihypertensive effects on S.H.R. and normotensive S.D rats, direct relaxant activity on isolated rabbit aorta, and ACE inhibitory activity. Menthae Herba and Arctii Fructus decreased blood pressure significantly in SHR, but not in normotensive rats, Direct vasodilatative effects on isolated rabbit aorta was not observed in any group. Chrysanthemi Flos, Menthae Herba, Mori Folium, and Arctii Fructus inhibited the actions of ACE dose-dependently. Therefore it is concluded that expelling pathogenic wind-heat drugs has not direct correlation with antihypertensive activity. However, it can be suspected that some drugs for dispersing the actions of wind and heat may regulate blood pressure through ACE inhibition and further study will be helpful to understand the mechanism.

이개강 전위피판을 이용한 외이도 입구 확장술

이호기,김희남,문성균,김은서,박남성 釜算慶南耳鼻咽喉科學會 1994 임상이비인후과 Vol.5 No.2

마이크로프로세서를 이용한 UTILITY CAR용 CONTROLLER 개발에 관한 연구

안호균,남징락,김태엽 國立 昌原大學校 産業技術硏究所 1999 産技硏論文集 Vol.13 No.-

This paper describes the development of Controller for the Utility Car using Microprocessor. The Utility Car is composed of Controller, separately excited DC motor, battery and potbox. It is easier for a digitalized controller using microprocessor to append new function than an analogized controller. For sensorless current control, the driver is used the feedback voltage of battery.