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      • 후박 및 은행엽 추출물을 함유한 치약의 임상 및 미생물학적 효과에 관한 연구

        김태일,염혜리,류인철,배기환,정종평 충남대학교 약학대학 의약품개발연구소 1996 藥學論文集 Vol.12 No.-

        Previous studies have shown that Magnoliae cortex and Ginkgo biloba extracts were showed on the antimicrobial and anti-inflammatory action, in vitro. The purpose of this study was to evaluate on the effect of antimicrobial and anti-inflammatory activity of Magnoliae cortex and Ginkgo biloba extracts containing dentifrice in gingivitis. 70 subjects with gingivitis were divided into an experimental group which performed normal oral hygiene procedure with Magnoliae cortex and Ginkgo biloba extracts containing dentifrice and a control group which also performed normal oral hygiene procedure with the same dentifrice without the natural extracts and completed a double-blind, cross-over study. At baseline and 3 weeks, subjects were assayed for clinical study by plaque index, gingival index, pocket depth, GCF rate, and microbiological study by subgingival dental plaque bacterial morphotypes by phase contrast microscopy, total anaerobes, total aerobes, Black pigmented bacteroides, A-actionomycetemcomitans, A.viscosus, C.rectus, S.sanguis, P.gingivalis, P.intermedia by bacterial culture and immunofluorescence microscopy. After 3 weeks using their respective dentifrices, reductions in the clinical indices of subjects were similar between the experimental dentifrice group and a control dentifrice group except for statistically significant much reductions in PI, GI, and GCF rate in the experimental dentifrice group as compared to control dentifrice group. Also statistically significant reductions in the motile rods and Spirochetes were found in both experimental group to compare with control group, however statistically much reduction in total anaerobes, Black pigmented bacteroides, and P.gingivalis, P.intermedia were found in the experimental dentifrice group as compared to control dentifrice group. This results indicates that Magnoliae cortex and Ginkgo biloba extracts containing dentifrice might be useful for elimination of gingival inflammation.

      • 症例(증례) : 관상동맥 스텐트로 치료한 베체트병에 동반된 급성 심근경색증 1예

        정혜진 ( Hey Jin Jeong ),김세인 ( Se In Kim ),김소리 ( So Ri Kim ),이규선 ( Kyu Sun Lee ),고은영 ( Eun Young Ko ),김성훈 ( Seong Hun Kim ),김성식 ( Sung Sik Kim ),임호영 ( Ho Young Yhim ),민경훈 ( Kyung Hoon Min ),이상일 ( Sang Il 전북대학교 의과학연구소 2004 全北醫大論文集 Vol.28 No.1

        베체트병은 반복되는 아프타성 구강궤양과 성기궤양 및 포도막염과 같은 눈의 반복적인 염증성 병변을 특징으로 하는 전신 질환이다. 베체트병에 동반된 심근경색은 매우 드물어서 소수의 증례만이 보고 되고 있다. 저자들은 베체트병 환자에서 발생한 심근 경색증 1예를 경험하였기에 보고하는 바이다. Behcet`s disease is a systemic disease of unknown cause, belonging to vasculitis pathologically. It rarely involves the coronary arteries. Coronary arteritis may lead to myocardial infarction and death, and the management of coronary lesions due to Behcet`s disease has been described only in a small number of patients. We experienced a -36-year-old man with Behcet`s disease who presented with acute coronary syndrome, and underwent balloon angioplasty and coronary stent implantation. The reduction of the coronary stenosis by balloon angioplasty induced immediate relief of chest pain. He has been still in reltively good health without chest pain during the 24 months of follow-up.

      • Analysis of monitoring Road-kill in Odaesan National Park

        Sang Jin Lim,Ki Yoon Kim,Woo Chan Lim,Hyeong Woo Ji,Baek Soon Choi,Tae Il Kim,Hyo Nam Kim,Ji Hong Min,Hey Ri Kim,Eui Kyeong Kim,Yung Chul Park 강원대학교 산림과학연구소 2017 강원대학교 산림과학연구소 학술대회 Vol.2017 No.11

        We surveyed mammalian roadkill at the National Route 6 (Jin-gogae to Songcheon, 18㎞) and a local road 446 (Odaesan National Park office to Sangwon-temple, 12㎞) in Odaesan National Park. Data of the surveys were analyzed by year, month, and species. Roadkills of 226 individuals were found at the survey areas. Of them, the road-killed 131 mammal individuals, 44 bird individuals, 40 reptile individual and 11 amphibian individuals were found during the survey period. High ratio of the road-kills was observed in mammals than the other animals. Among mammalian species, high ratio of the road-kills was observed in squirrels. There were road-kills of three endangered species, containing otters, yellow-throated marten and leopard cats. According to the analyses of annual road-kills, roadkills of 104 cases were occurred and highly frequent in 2014, following by roadkills of 81 cases in 2015, and then those of 41 cases in 2016. Most ases of the roadkills occurred in summer (June to September). The results will contribute to establishing management for reduction of roadkill in Odaesan National Park.

      • SCIEKCI등재

        Genomic comparison of insecticides and herbicide in human hepatoma (HepG2) cell line

        An, Yu-Ri,Kim, Seung-Jun,Park, Hey-Won,Oh, Moon-Ju,Kim, Youn-Jung,Ryu, Jae-Chun,Hwang, Seung-Yong The Korean Society of Toxicogenomics and Toxicopro 2010 Molecular & cellular toxicology Vol.6 No.4

        Pesticide is a chemical substance, biological agent, antimicrobial, disinfectant or device used against any pest, and it can be grouped in several different ways. Atrazine is one of the most commonly used herbicides found in the rural environments, permethrin and prallethrin are pyrethroid insecticides. In this study, we compared the characters of herbicide and insecticide by cytotoxicity and microarray experiments. In the cytotoxicity tests, we couldn't find specific chemical features. However, in the gene expression analysis, we found that insecticides affects to RNA processing and RNA metabolism, and especially, in the energy metabolism, such as generation of precursor metabolites and energy, and energy derivation by oxidation of organic compounds, herbicides and insecticides are differently working. This study provides characteristics of two pesticides by checking the transcriptional change.

      • KCI등재후보

        미용실 종사자들이 두피관리 시술을 기피하는 요인 및 개선방안에 관한 연구

        김순경 ( Soon Kyoung Kim ),진유리 ( Yu Ri Gin ),김혜숙 ( Hey Suk Kim ),장선엽 ( Sun Yeop Chang ) 대한미용학회(구 대한미용과학회) 2011 대한미용학회지 Vol.7 No.1

        As customer`s interest in scalp care is on rise lately, the scalp care treatments show to be increasing not only at beauty shops but also various places such as scalp care center, hospitals and clinics and skin care shops. In the meantime, since the beauty shops do much more on hair-styling and service scalp care service as one of options, they showed the limitation to fail to satisfy the customers enough who want scalp care and have beginning alopecia and the specialty in scalp care of beauty shops became an issue. Therefore, the needs for scalp care as a special service in order to expand the customers with scalp care treatment of beauty shops. To do so, in addition to the recognition survey of the workers for scalp care factors, there is believed to be scalp care avoidance factors recognized by the workers, which led the expansion of scalp care customers to a failure despite of continued education and system at the beauty shop. the problem recognition at the workers avoidance factor of scalp care customers indicated work force lack. The worker`s recognition and the status of the scalp care are to be identified, whereby the purpose of the study was to increase revenue of the beauty shop from continued scalp care and enhance the customer loyalty by making scalp care service active with development of beauty shop`s differentiated care programs and various care manuals so as to meet customer needs as well as to suggest improvement methods of scalp care treatment.

      • KCI등재

        35세 이상 고령 산모의 산과적 예후

        박희진 ( Hee Jin Park ),이숙환 ( Sook Hwan Lee ),차동현 ( Dong Hyun Cha ),김인현 ( In Hyun Kim ),전혜선 ( Hye Sun Jun ),이경진 ( Kyoung Jin Lee ),송송아 ( Song Ah Song ),박혜리 ( Hey Ri Park ),정창조 ( Chang Jo Chung ),이정노 ( Ch 대한산부인과학회 2006 Obstetrics & Gynecology Science Vol.49 No.10

        목적: 본 연구의 목적은 35세 이상이 고령 임신에서의 산과적 예후를 평가하기 위한 것이다. 연구 방법: 차병원에서 2004년 1월부터 2004년 12월까지 산전 진찰을 받고 분만한 산모를 대상으로 의무기록을 분석하는 후향적 연구를 시행하였다. 환자들은 산모의 나이에 따라 1) 35세 미만 2) 35-39세 3) 40세 이상으로 나누었고, 산모의 임신으로 인한 합병증 발생에 나이가 미치는 영향을 분석할 때는 35세 미만의 산모군을 대조군으로 하였으며 과거 임신력, 체지방 지수 (body mass index), 과거 내과적 병력, 임신 방법 등 영향을 미칠 수 있는 다양한 요인에 대하여 나이군 별로 분산 분석을 이용하여 비교하였다. 산과적 합병증의 발생 위험 비교는 카이제곱 검정법 (chi-square test)을 이용하였고 합병증의 비차비 (odds ratio)를 구하였다. 결과: 총 2646명의 산모 데이터를 분석하였고 35세 미만이 2,245명 (84.9%), 35세 이상-39세 이하가 350명 (13.2%), 40세 이상의 산모는 51명 (1.9%) 이었다. 태아의 염색체 이상은 35세 이상의 산모에서 의미 있게 증가하였다 (OR 3.9; 35-39세, 8.8; 40세 이상). 자간전증 (preeclampsia)과 임신성 당뇨의 발생은 산모군간 차이가 없었다 (OR 1.2; 35-39세, 1.3; 40세 이상). 전치 태반 (OR 1.8)과 선천성 기형 (OR 2.8)은 35-39세 산모군에서만 다소 증가되었다. 태반 조기 박리 (placenta abruption)의 발생은 차이가 없었다. 조기 양막 파수 (preterm premature rupture of membranes: PPROM)는 나이가 증가할수록 위험도가 증가하였고 (OR 1.3; 35-39세, 3.2; 40세 이상: p=0.041), 조기 분만 (preterm delivery)도 증가하였으나 (OR 1.3;35-39세, 1.9; 40세 이상) 통계적으로 유의성은 없었다 (p=0.121). 저체중아 (low birth weight)와 거대아 (macrosomia)의 출산은 산모군 별로 통계적 의의가 없었으며 (p=0.899), 제왕 절개의 빈도는 산모의 나이가 증가함에 따라 현저하게 증가하였다 (OR 2.0; 35-39세, 5.5; 40세 이상). 신생아 중환자실 입원력은 산모군간 차이가 없었으며 (OR 0.9; 35-39세, 1.1; 40세 이상), 주산기 태아 사망은 35세 이상 산모군에서만 다소 증가하였으나 (OR 1.4) 통계적 의의는 없었다 (p=0.807). 결론: 결론적으로 산과적 합병증 중 태아의 염색체 이상과 제왕 절개 빈도, 조기 양막 파수의 위험도는 나이에 따라 증가하지만, 다른 산과적 합병증에 고령 임신이 미치는 영향은 크지 않다고 볼 수 있다. Objective: To estimate the effect of maternal age on obstetric outcomes, a retrospective analysis was done. Methods: Twenty six hundred and forty six women who delivered a singleton baby at our hospital from January 1, to December 31, 2004 were enrolled in this study. Subjects were divided into 3 age groups; 1) less than 35 years, 2) 35-39 years, and 3) 40 years and older. Chi-square test was used to assess the effect of age on obstetrics outcome. Then the odds ratio was calculated to represent clinically meaningful risk. Results: A total of 2646 women with complete data were available; 2245 (84.9%) less than 35 years of age; 350 (13.2%) 35-39 years; and 51 (1.9%) 40 years and older. Increasing age was significantly associated with chromosomal abnormalities (OR 3.9and 8.8 for ages 35-39 years and age 40 years and older, respectively), Preterm premature rupture of membranes (OR 1.3 and 3.2) and cesarean delivery (OR 2.0 and 5.5). Patients aged 35-39 years were at increased risk for placenta previa (OR 1.8) and congenital anomaly (OR 2.8) but these were not statistically significant. The rate of the preterm delivery was increased by age (OR 1.3 and 1.9 for ages 35-39 years and age 40 years and older, respectively) but it was not statistically significant (p=0.121). We did not find advanced maternal age to be associated with a statistically increased risk for preeclampsia, congenital anomaly, gestational diabetes, placenta abruption, low birth weight, macrosomia, neonatal morbidity (NICU admission), and perinatal loss. Conclusion: In conclusion, although the likelihood of adverse outcomes increases with maternal age, patients and obstetric care providers can be reassured that overall maternal and fetal outcomes are favorable in this patient population.

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