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      • 冠岳樹木園地域內 荒廢山地土壤의 肥沃化를 통한 綠化促進에 關한 硏究

        李宗學,麻鎬燮,權台鎬,李憲浩,禹保命 서울大學校農業生命科學大學附屬樹木園 1984 서울大學校 樹木園 硏究報告 Vol.- No.5

        冠岳樹木園地域의 山腹斜面은 地質的으로 대보화강암에서 풍화생성된 거친 돌부수러기가 많은 粗砂質壤土로 구성되었으므로 表土層의 土壤流失이 심하여 土深이 대단히 얕거나 岩盤露出이 심하여 林木生長이 심히 不良한 地帶로서,山地의 地力恢復 및 現存하는 散生樹木의 生長力恢復을 通한 山地綠化保全이 시급히 요청되고 있다. 이와같은 요청에 부응하여 荒廢地斜面에 自生하고있는 주요한 4樹種(소나무, 리기다소나무, 노간주나무, 철쭉)에 대하여 山地施肥效果 試驗을 春期와 秋期로 나누어 실시한 결과 樹高 및 直徑生長量에 있어서 無施肥區에 比하여 현저한 施肥效果가 인정되었다. 따라서 冠岳山地帶의 荒廢地를 조속히 復舊綠化하기 위해서는 砂防土木的 工事方法 및 砂防造林的 播植方法이외에도 현존 수목의 保全 및 生長力恢復을 통한 速成綠化方法도 채용되어야 할 것이다. Hillsides in the Kwanak arboretum area were composed mainly of coarse sandy loam having relatively high proportion of rough weathered debris derived from the Daebo granite geologically. Owing to heavy soil erosion resulted to shallow soil depth and heavy rock exposures, the growing trees in this type of surface soil are very poor in their growth. For woody plant vegetation establishment in this montain area, it is urgent to recover the fertility of soil and the growth of existing trees. For this purpose, in spring and autumn season in 1983∼84 the fertilization experiment was conducted with the 4 principal native species(Pinus densiflora, Pinus rigida, Juniperus rigida, Rhododendron schlippenbachii) growing in this denuded forest land, and the effects of fertilized tree plots were more prominent than the control plot in both height and root-collar diameter growth. Therefore, the accelerating measures of vegetation rehabilitation through conservation of existing trees and recovery of tree growth by forest fertilization practices, besides forest engineering measur es and soil erosion control afforestation measures, could be acceptable as the measures for the recovery of denuded forest land in Mt. Kwanak area.

      • 冠岳樹木園地域內 荒廢山地土壤의 肥沃化를 통한 綠化促進에 關한 硏究

        李宗學,麻鎬燮,李憲浩,權台鎬,禹保命 서울大學校 農科大學 1984 서울대농학연구지 Vol.9 No.2

        冠岳樹木園地域의 山復斜面은 地質的으로 대보화강암에서 풍화생성된 거친 돌부수러기가 많은 粗砂質壤土로 구성되었으므로 表土層의 土壤流矢이 심하여 土深이 대단히 얕거나 岩盤露出이 심하여 林木生長이 심히 不良한 地帶로서, 山地의 地力恢復 및 現存하는 散生樹木의 生長力恢復을 通한 山地綠化保全이 시급히 요청되고 있다. 이와같은 요청에 부응하여 荒廢地斜面에 自生하고 있는 주요한 4樹種(소나무, 리기다소나무, 노간주나무, 철쭉)에 대하여 山地施肥效果 試驗을 春期와 秋期로 나누어 실시한 결과 樹高 및 直徑生長量에 있어서 無施肥區에 比하여 현저한 施肥效果가 인정되었다. 따라서 冠岳山地帶의 荒廢地를 조속히 復舊綠化하기 위해서는 砂防土木的 工事方法 및 砂方造林的 播植方法이외에도 현존 수목의 保全 및 生長力恢復을 통한 速成綠化方法도 채용되어야 할 것이다. Hillsides in the Kwanak arboretum area were composed mainly of coarse sandy loam having relatively high proportion of rough weathered debris derived from the Daebo granite geologically. Owing to heavy soil erosion resulted to shallow soil depth and heavy rock exposures, the growing trees in this type of surface soil are very poor in their growth. For woody plant vegetation establishment in this montain area, it is urgent to recover the fertility of soil and the growth of existing trees. For this purpose, in spring and autumn season in 1983~84 the fertilization experiment was conducted with the 4 principal native species(Pinus densifltora, Pinus rigida, Juniperus rigida, Rhododendron schlippenbachii) growing in this denuded forest land, and the effects of fertilized tree plots were more prominent than the control plot in both height and root-collar diameter growth. Therefore, the accelerating measures of vegetation rehabilitation through conservation of existing trees and recovery of tree growth by forest fertilization practices, besides forest engineering measur es and soil erosion control afforestation measures, could be acceptable as the measures for the recovery of denuded forest land in Mt. Kwanak area.

      • SCOPUSKCI등재

        Omeprazole 투여시 위산분비 억제능에 대한 CYP2C19 의 영향

        박수헌(Soo Heon Park),김종원(Jong Won Kim),이수연(Soo Youn Lee),최명규(Myung Gyu Choi),김재광(Jae Kwang Kim),정인식(In Sik Chung),정규원(Gyu Won Chung),선희식(Hee Sik Sun),박두호(Doo Ho Park) 대한소화기학회 2001 대한소화기학회지 Vol.38 No.6

        Background/Aims: CYP2C19 has an important role in the catabolism of several proton pump inhibitors. However, the relative contribution of CYP2C19-mediated metabolism varies among the different proton pump inhibitors. We investigate to determine the effect of CYP2C19 genotype status on intragastric pH during dosing with omeprazole. Methods: The subjects were 16 healthy volunteers. Their CYP2C19 genotype status was determined by a polymerase chain reaction-restriction fragment length polymorphism method. Twenty-four-hour monitoring of intragastric acidity were performed on the day without medication and day 4 after omeprazole administration. Results: A single dose of omeprazole significantly decreased 24 hour intragastric acidity (1.7±0.3 vs. 5.1±0.4). Subjects were divided into three groups on the basis of their CYP2C19 genotype status: homozygous extensive metabolizers (Ho-EMs, n=5), heterozygous extensive metabolizers (Ht-EMs, n=6), and poor metabolizers (PMs, n=5). Median 24 hour intragastric pH in the Ho-EM group was 3.1 compared with 5.5 in Ht-EM group and 5.9 in PM group(P<0.05). The median pH during omeprazole administration was influenced by CYP2C19 genotype. On the other hand, the Helicobacter pylori infection did not influence the median intragastric pH during omeprazole administration (p= NS). Conclusions: The effects of omeprazole on intragastric acidity is influenced by the CYP2C19 polymorphism. (Korean J Gastroenterol 2001;38:399-404)

      • KCI등재
      • B형 만성 활동성 간염 환자에서 Prednisolone 단기이탈 및 Alpha Interferon 병합요법의 효과

        이종선,김병호,성자원,허승식,이기천,정현용,이헌영,김영건 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.2

        To evaluate the safety and efficacy of Pd withdrawal followed by recombinant alpha- Interferon 2b therapy. Nine patients were given a single daily subcutaneous injection of ^α-Interferon at a dose of 3 x 10 exp(6) units/day for first weeks and thrice weekly for next 15 weeks (maintenance) after pd tappered over 6 weeks. To evaluate the efficacy of therapy, we measured serum aminotransferase activities monthly during and after therapy, and also measured serm HBsAg, HBeAg and DNA probe before and after therapy. To evaluate the safety of therapy, all patients checked peripheral blood WBC, Hemoglobin, Platelet, BUN and Creatinine. The results were as follows : 1. In control group, the normalization of s-AST & ALT level, negative seroconversion of DNA probe & HBeAg were observed in 1/12(8%) & 7/10(17%), 0/10(0%) & 0/12(0%) at 6 months later, and maintained response in 1/11(9%) & 1/11(9%), 2/9(22%) & 2/11(18%) until 1 years later. 2. In treatment group, Serum AST and ALT returned to normal in 8/9 & 8/9 cases (89%) after 1 montns Tx. (mean serum AST : 33±8, ALT : 34±12 IU/ml) and maintained to normal response in 5/9(56%) & 6/9 cases(67%)after 6 months Tx. (mean s-AST : 55±43, ALT : 66±84 IU/ml), 3/9(33%) & 4/9 cases(44%) after 1 years Tx. It was statistically significant reponse except s-AST of after 1 years Tx. 3. In treatment group, s- HBeAg returned to normal in 3/9 cases(33%) after 1 months Tx., and maintained to normal response in 1/7 & 1/4 cases among follow up patients in after 6 & 12 months Tx. Serm DNA probe level were observed significantly negative seroconversion in 8/9 cases(89%) after 1 months Tx. (p<0.003), and maintained to negative response in 2/6 & 1/3 cases after 6 & 12 months Tx. 4. Serum AST, ALT, HBeAg and DNA probe were not significantly correlated with therapeutic response in relation to histologic diagnosis. 5. Fever and myalgia were noted in 9(100%) & 6(67%) cases. Headache, mild hair loss, anorexia, nausea, facial flushing & diarrhea were noted in few cases. Peripheral WBC(3cases) & platelet counts(3cases) were decreased transiently. This study shows that Pd withdrawal followed by recombinant alpha Interferon 2b therapy may be safe and effective in decrease the level of s-DNA probe, transaminase activity, loss of HBeAg and less adverse effect of clinical and hematologic examinations in patients with CAH type B. But it was necessary for study with large number of patients, more prolonged follow up duration and more strict control study.

      • 중학생의 현장 체험학습 공간에 관한 연구 : 부산시를 중심으로

        이성호,김헌숙 부산대학교 도시문제연구소 2000 都市硏究報 Vol.10 No.-

        The purpose of this study is to recognize the necessity and management of field experiential learning for middle school students, to find problems of the space for field experiential learning and suggest how to improve the problems. For this purpose, two kinds of methods are adapted ; theoretical method through the existing studies related to field experiential learning and positive method through the questionnaires of middle school students in all the grades and teachers working at middle schools in Pusan. Frequency and Cross Tabulation Analyses are carried out using SPSS for windows.

      • KCI등재

        식품 위해 요소중점 관리 기준에 대한 서울지역 사업체 급식관리자의 위생관리평가

        이헌옥,심재영,김영경,조민호,최호순,엄애선 한국조리과학회 2001 한국식품조리과학회지 Vol.17 No.6

        Hazard Analysis Critical Control Point(HACCP) is becoming an important component of food safety worldwide. The aim of this study was to investigate comprehensively the education and knowledge level of food service managers on HACCP as well as applying HACCP system to industrial foodservice. Total 247 foodservice managers participated in the survey and 159 responses were used for analysis. The results were as follows; 1) 89% of foodservice managers were educated about HACCP, and 40.9% felt they did fully understand HACCP and 47.8% did half. 2) The score for the implementation of HACCP was in the order of apparatus and facility sanitation, personal sanitation, and time-temperature/etc. sanitation. 3) Foodservice managers who were taught HACCP kept a deep attention to food and personal sanitation, compared with those without education(p<0.05). However, the education time on HACCP affected conducting safety management. The results suggest that education and understanding of HACCP are positively related, and understanding of HACCP has a positive influence on conducting safety management.

      • 위암 환자에서 세포성 면역 기능에 관한 연구

        이재익,윤일국,이종선,김종완,장준,안정기,송민호,정현용,이헌영,김삼용,김영건 충남대학교 암연구소 1991 癌共同硏究所 硏究誌 Vol.1 No.1

        We performed a variety of lymphocyte stimulation tests, delayed hypersensitivity skin tests, and enumeration of several lymphocyte subpopulations in 21 patients with gastric cancer who did not receive any form of anticancer therapy, and in 20 healthy controls. The gastric cancer patients had significantly decreased number and total score of positive reactions in delayed hypersensitivity skin tests compared with the healthy controls. The percent of CD_(4) positive lymphocytes in the gastric cancer patients was significantly decreased compared to the normal control subjects, but it had no correlation with the total score of delayed cutaneous hypersensitivity reactions. The ratio of helper to suppressor cells was lower in the cancer group. The uptake of 3H-thymidine was markedly depressed in cancer patients when stimulated with various mitogens. There was little correlation between any of the stimulation tests and any of the lymphocyte subpopulation proportions to delayed hypersensitivity cutaneous reactions. Optimal proliferative response was found in lymphocytes stimulated with 10 micrograms of concanavalin-A and 10 microgram of phytohemagglutinin. Advanced stage patients had greatly depressed delayed hypersensitivity skin reactions and proliferative responses to mitogens compared with localized diseases. These results suggest that gastric cancer patients have depressed cellular immune functions, which mainly result from the decreased helper cells and defects in functional proliferative response to mitogens. Interleukin-2 and interferon-gamma restored the in vitro proliferative response of lymphocyte in patients with gastric cancer.

      • Exo 電子放射를 利用한 線量計의 開發

        李春鎬,徐憲全 全北大學校 1980 論文集 Vol.22 No.-

        The TSEE glow curve of BeO irradiated to X-ray was obtained by using 2π gas flow GM counter, and the temperature, which was recorded as a function of time, raised at the rate of 0.7℃ per second from 20℃ to 500℃. It was found that there are three peaks of TSEE glow curves at 505, 632 and 710˚K. The values of trap depth and frequency factor for three peaks was obtained by using the method of Kelly-Laubitz and De Muer. Following the analysis of De Muer, the evaluated values of σ_2/σ_1 has been found to satisfy the limit 0<σ_2/σ_1<1, which corresponds to the first order like process of Kelly-Laubitz analysis. The dosimetric characteristic curve of BeO for the peak at 505˚K appears to be a good linear is the dose range from 2×10^-3 mr to 1×10^-1 mr and there is no any fading at room temperature.

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