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남상운,허연정,심옥자,심상일,이호상 안성산업대학교 1998 論文集 Vol.30 No.-
This study was carried out to investigate energy saving effect and thermal insulation characteristics of double film water curtain system during the coldest season in greenhouse. A double film water curtain system is a ground water spraying system between double layered plastic film, and it is able to make uniform water curtain. The experimental greenhouses were plastic greenhouses of two types. A type-Ⅰ was a two-thirds arched shape and its area was 350㎡ . A type-Ⅱ was a triangle shape and its area was 190㎡. Both greenhouses were cultivated with cactus. The minimum outside air temperature ranged was -2.6 to -16.7℃ and nocturnal ambient mean temperature was -6.5℃. The experimental greenhouses have maintained the air temperature above 2℃ of type-Ⅰ and 8℃ of type-Ⅱ. The ground water spraying flow rates of these greenhouses were 7.0ℓ/㎡hr of type-Ⅰ and 4.3ℓ/㎡hr of type-Ⅱ. The overall heat transfer coefficient of type-Ⅰ greenhouse was calculated at 1.97 kcal//㎡hr℃ and type-Ⅱ was 1.44 kcal/㎡hr℃. The energy saving rate of type-Ⅰ greenhouse was estimated and 78.1% and type-Ⅱ was 98.9%.
Jeong, Hyun Jeong,Lee, Hyun Ju,Ko, Jung Hwa,Cho, Bum-Joo,Park, Se Yeon,Park, Jong Woo,Choi, Se Rang,Heo, Jang Won,Yoon, Sun-ok,Oh, Joo Youn American Association of Immunologists 2018 Journal of Immunology Vol. No.
<P>Resolution of inflammation is an active process that leads to tissue homeostasis and involves multiple cellular and molecular mechanisms. Myeloid-derived suppressor cells (MDSCs) have recently emerged as important cellular components in the resolution of inflammation because of their activities to suppress T cell activation. In this article, we show that HLA-DR<SUP>−</SUP>CD11b<SUP>+</SUP>CD33<SUP>+</SUP>CD14<SUP>+</SUP> human MDSCs and CD11b<SUP>+</SUP>Ly6G<SUP>−</SUP>Ly6C<SUP>+</SUP> mouse MDSCs markedly increased in patients and mice during and before the resolution phase of autoimmune uveoretinitis. CD11b<SUP>+</SUP>Ly6C<SUP>+</SUP> monocytes isolated from autoimmune uveoretinitis mice were able to suppress T cell proliferation in culture, and adoptive transfer of the cells accelerated the remission of autoimmune uveoretinitis in mice. Alternatively, depletion of CD11b<SUP>+</SUP>Ly6C<SUP>+</SUP> monocytes at the resolution phase, but not CD11b<SUP>+</SUP>Ly6G<SUP>+</SUP> granulocytes, exacerbated the disease. These findings collectively indicate that monocytic MDSCs serve as regulatory cells mediating the resolution of autoimmune uveoretinitis.</P>
Jeong Heo,Yoon Jun Kim,Sung Wook Lee,Youn-Jae Lee,Ki Tae Yoon,Kwan Soo Byun,Yong Jin Jung,Won Young Tak,Sook-Hyang Jeong,Kyung Min Kwon,Vithika Suri,Peiwen Wu,Byoung Kuk Jang,Byung Seok Lee,Ju-Yeon Ch 대한내과학회 2023 The Korean Journal of Internal Medicine Vol.38 No.4
Background/Aims: Despite the availability of direct-acting antivirals (DAAs) for chronic hepatitis C virus (HCV) infection in Korea, need remains for pangenotypic regimens that can be used in the presence of hepatic impairment, comorbidities, or prior treatment failure. We investigated the efficacy and safety of sofosbuvir–velpatasvir and sofosbuvir–velpatasvir–voxilaprevir for 12 weeks in HCV-infected Korean adults. Methods: This Phase 3b, multicenter, open-label study included 2 cohorts. In Cohort 1, participants with HCV genotype 1 or 2 and who were treatment-naive or treatment-experienced with interferon-based treatments, received sofosbuvir–velpatasvir 400/100 mg/day. In Cohort 2, HCV genotype 1 infected individuals who previously received an NS5A inhibitor-containing regimen ≥ 4 weeks received sofosbuvir–velpatasvir–voxilaprevir 400/100/100 mg/day. Decompensated cirrhosis was an exclusion criterion. The primary endpoint was SVR12, defined as HCV RNA < 15 IU/mL 12 weeks following treatment. Results: Of 53 participants receiving sofosbuvir–velpatasvir, 52 (98.1%) achieved SVR12. The single participant who did not achieve SVR12 experienced an asymptomatic Grade 3 ASL/ALT elevation on day 15 and discontinued treatment. The event resolved without intervention. All 33 participants (100%) treated with sofosbuvir–velpatasvir–voxilaprevir achieved SVR 12. Overall, sofosbuvir–velpatasvir and sofosbuvir–velpatasvir–voxilaprevir were safe and well tolerated. Three participants (5.6%) in Cohort 1 and 1 participant (3.0%) in Cohort 2 had serious adverse events, but none were considered treatment-related. No deaths or grade 4 laboratory abnormalities were reported. Conclusions: Treatment with sofosbuvir–velpatasvir or sofosbuvir–velpatasvir–voxilaprevir was safe and resulted in high SVR12 rates in Korean HCV patients.
Investigation on the Relationship Between Transition Energy and the Color Change of Cu–M Alloys
Yeon Beom Jeong,Sung Hwan Hong,Jeong Tae Kim,Hae Jin Park,Young Seok Kim,Hoo Dam Lee,Jong Kook Lee,Sang Chul Mun,Yun Jung Hwang,Kwang Heo,Ki Buem Kim 대한금속·재료학회 2019 METALS AND MATERIALS International Vol.25 No.3
A series of Cu–M color alloys were investigated with two additional elements, Zn and Ga, that have adequate solubility tocopper, which means that a wide region of solid-solution phase exists in the Cu-rich area in terms of color variation. Tomeasure the color change of the alloys, the reflectivity difference analysis, the color difference and the transition energywere utilized. As the amount of minor alloying elements increased, the proportional relationship was found between thetransition energy and the color difference compared to copper, for example, the color difference mounted with the increaseof transition energy. A significant color difference was found when gallium was employed as the minor element. In otherwords, the influence of gallium on the color change was more evident than with Zn. It appears to be about 4.5 of the colordifference when 3 at% of gallium was added.
Radiologic screening of maternal periodontitis predicts adverse pregnancy and neonatal outcomes
( Jeong Min Kim ),( Youngmi Jeong ),( Ju Sun Heo ),( Jung Soo Park ),( Ho Yeon Kim ),( Geum Joon Cho ),( Soon-cheol Hong ),( Min-jeong Oh ),( Hai-joong Kim ),( Ki Hoon Ahn ) 대한산부인과학회 2020 대한산부인과학회 학술대회 Vol.106 No.-
Objective: Dental screening is essential for the women who decide to conceive a baby or who get pregnancy. However, clinical screening such as periodontal probing could be quite time-consuming, highly discomforting, and inaccurate method. The aim of this study was to assess whether the severity of periodontitis classified by radiologic screening in accordance with the 2017 consensus classification was related to the adverse pregnancy and neonatal outcomes. Methods: One-hundred sixty-five mothers who underwent panorama x-rays within five years before and after the time of delivery, and their singleton neonates were included in this study. Their medical records were retrospectively reviewed. Results: Twenty-two mothers (13.3%) had severe periodontitis (SP), and 143 mothers (86.7%) had mild/moderate periodontitis (MP). Multivariate logistic regression analysis revealed that maternal SP was independently associated with uterine leiomyoma (OR: 5.555, 95% CI: 1.371-22.503, P = 0.016) and small for gestational age (OR: 4.488, 95% CI: 1.116-18.058, P = 0.035). Among the preterm infants, infants in the SP group had not only lower birth weight, but also lower z-score of birth weight. Incidences of retinopathy of prematurity (ROP) and treated patent ductus arteriosus (PDA) were significantly higher in the SP group than in the MP group (ROP: 50% vs 0%, P = 0.008, PDA: 33.3% vs 0%, P = 0.046). Conclusion: Radiologic screening of maternal periodontitis can predict adverse pregnancy and neonatal outcomes. It could be a useful screening method for predicting adverse outcomes as well as diagnosing SP in pregnant women.
한국의 40세 이상 남녀의 소득, 결혼, Body Mass Index, 건강행태요인이 당뇨에 미치는 영향
허연정(Yeon-Jeong Heo),손미아(Mia Son),현혜진(Hye-jin Hyun) 한국자료분석학회 2021 Journal of the Korean Data Analysis Society Vol.23 No.3
이 연구는 한국인유전체역학조사사업(KoGES)에서 2001년부터 2013년 사이에 구축된 지역사회기반코호트(안산, 안성), 도시기반코호트, 농촌기반코호트 자료를 통합하여 구축한 한국의 만 40세 이상 성인 남녀를 210,413명을 대상으로 소득수준, 결혼, BMI, 건강행태요인이 당뇨병에 미치는 영향을 분석하였다. 당뇨병에 미치는 위험요인을 보면, 소득이 당뇨병과 역의 선형을 보이면서, 소득이 적을수록 당뇨병이 증가하는 경향이 뚜렷하게 나타났다. 남성, 고령, 사별, 비만, 음주, 흡연이 당뇨병에 영향을 미치는 것으로 나타났으나, 소득과 결혼이 건강행태요인들보다 당뇨병에 더 많은 영향을 미치고 있었다. 이 연구는 당뇨병 발생 위험요인이 높은 집단은 소득 수준이 낮고, 결혼상태가 별거, 이혼한 고령의 남성 집단임을 보여주고 있다. 이 연구는 당뇨병 발생위험이 소득수준, 결혼상태와 같은 사회경제적 상태에 따라 차이가 있어 당뇨병 중재 프로그램개발과 적용을 고려할 때 인구학적 특성과 사회경제적 상태를 고려한 중재가 필요함을 제시하였다는 점에서 의의가 있다. 특히 당뇨병의 치료 및 관리에 있어서 소득수준에 따른 다양한 중재방안이 이루어져야 할 것이다. This study was conducted by integrating data from community-based cohorts (Ansan, Anseong), urban-based cohorts, and rural-based cohorts established between 2001 and 2013 by the Korean Genome Epidemiology Survey (KoGES) in Korea, and was constructed by those over the age of 40 in Korea. The effects of income level, marriage, BMI, and health behavior factors on diabetes were analyzed for 210,413 adult men and women. The effect on diabetes was inversely linear with income, and as the income decreased, the tendency to increase diabetes was evident. Men, old age, bereavement, obesity, drinking, and smoking were found to have an effect on diabetes, but income and marriage had more influence on diabetes than health behavior factors. In conclusion, it is necessary to adjust health behavioral factors for elderly male subjects with low income, separated from their marital status, and divorced with risk factors for diabetes, and to prepare interventions to improve awareness and prevent diabetes.