천막상부 역형성 성상세포종과 다형성 교모세포종 환자에서 수술적 종양제거 범위가 생존에 미치는 효과 : 휴향적 다변량 분석법에 의한 연구 A Retrospective Multivariate Analysis

정희원,심기범,정천기 대한신경외과학회 1992 Journal of Korean neurosurgical society Vol.21 No.12

A retrospective analysis was performed to evaluate the prognostic factors affecting the length of survival of 86 adults(age>15 years) with newly diagnosed biopsy-proven supratentorial anaplastic astrocytomas and glioblasmas treated at the Seoul National University Hospital and Korea Cancer Center Hospital between June, 1980 and June, 1990. Of the 86 patients, 44 patients (51%) had anaplastic astrocytoma, and 42 patients(49%) had glioblastoma multiforme. The mean age was 40 years, and mean initial Karnofsky performance score(KPS) was 70. The duration of follow up ranged from 3 months to 85 months. Survival curves were generated using the Kaplan-Meier curves. Median survival times were compared using the log-rank test. Additionally, for a study of the prognostic importance of multiple factors acting simultaneously, the proportional hazards regression model of Cox was used in which survival times were modeled as a function of the important independent variables identified in the univariate analysis. Categories included biopsy, partial resection, and gross total resection. Seventeen patient(20%) who underwent a gross total resection of their tumors had median survival time and 6-, 12-, 24- month survival rates of approximately 33 months, 94%, 80% and 57% respectively, when compared to 13 months, 74%, 53%, 34% for fifty patients(60%) who had partial resection. Multivariate analysis demonstrated that the age(p=0.010), the initial KPSP(p<0.001), the histology(p<0.001) and the extent of resection (p=0.016) were significant and independent variables influencing survival. These results suggest that gross total resection of supratentorial anapalstic astrocytomas and glioblastomas is directly associated with longer survival when compared to partial resection or biopsy.

急速反復動作能力에 의한 女性의 機能에 關한 硏究

鄭淸喜,裵小心 同德女子大學校 1975 同大論叢 Vol.5 No.1

motor avidity of human extremity is of essential factor for sports The purpose of this research is of as follow. ① clarify individual differences in rapid response ability of coed ② clarify effect of extremity ability for sports The theoretical background of the research is the models suggested by ikai, mazei, kawazaki, 8 subjects were relected for the research and consisted with 4 players and 4 nonplayers. method of measuremet of extremity ability was used tapping test at the rate of 50mm a second. The results are as follow; ① table tennis players are most superior in rapid extremity ability and athletic sport players have no differences with nonplayers. ② There are me differences between men and worsen in rapid response ability of extremity. ③ There are severe differences between left and right extremity in rapid response ability except table temus players. ④ There are severe individual differences in rapid response ability ⑤ ability of noneffective extremity is in proportion to effective extermity.

아스피린 불내성 천식환자에서 포도상구균에 대한 혈청 특이 IgE 항체 측정

오정미,김승현,윤성호,김상하,서창희,남동호,박해심 대한알레르기학회 2004 천식 및 알레르기 Vol.24 No.2

光照射에 의한 콩나물의 質的 變化

金明姬,元惠心,李正和,林容順,張美花 효성여자대학교 가정대학 학도호국단 1984 家政大論集 Vol.3 No.-

光의 照射에 의한 콩나물의 質的變化를 調査할 目的으로 光度 및 光質別 處理를 하여 成長狀態, Vitamin C, chlorphnyll, cellulose등의 含量과 質感에 對한 官能檢査를 行하였으며 chlorophyll과 vitamin C의 關係를 chloramphenicol 處理에 의하여 調査해 보았다. 그 結果 白色光의 경우 50 lux와 100 lux 處理로 vitamin C의 含量 增加와 cellulose등의 生成이 促進되었으며 質感이 暗所보다 良好하였다. 그러나 200 lux 하에서는 매우 不良하였다. blue光은 他光보다 cellulose와 vitamin C生成에 效果的 이었다. chlorophyll과 vitamin C의 含量과는 直接的인 關係가 없고 다만 光照射와의 關聯性이 있는 것으로 推定되었다. This study was carried out to evaluate the quality of green soybean sprouts grown under light. The soybean was germinated under light through blue, red and white polyethylene films at 25℃ for 10 hours a day, and light intensity was controlled 50 to 200 lux. The contents of Vitamin C. cellulose and chlorophyll were determined and checked up texture by sensory evaluation of the soybean sprouts soup. In addition, the relationship of chlorophyll and Vitamin C was measured by treatment of chloramphenicol which has inhibitory effect of chloroplast, chlorophyll accumulating site. Vitamin C and cellulose contents were all increased by irradiation of white light at 50 and 100 lux and also texture of the sprouts was better than it of the sprouts grown under darkness while, it was very tough under 200 lux. Blue light was more effective for biosynthesis of Vitamin C and cellulose than white and reg light. Biosynthesis of chlorophyll was not relative to Vitamin C content directly. but the relationship may be concerned with light irradiation.

부재료 첨가에 따른 오이지의 펙틴질 변화에 관한 연구

한정희,심영현 서울여자대학교 자연과학연구소 1997 자연과학연구논문집 Vol.9 No.-

부재료 첨가에 따른 오이지의 제조에서 pH, Texture(Blossom end, Middle, Stem end), 펙틴 조성의 변화(AIS, HWSP, HXSP, HCISP), hardness와 펙틴질 사이의 상관관계에 대해서 다음과 같은 결론을 얻었다. 1. 담금액의 pH 대조군과 부재료 첨가군의 pH 변화를 보면 모든 실험군에서 빠른 감소를 보이는데 E처리구는 다른 부재료 첨가군보다 빠른 숙성 7일째에 pH 3.5에 도달하고, 그 수준을 35일까지 유지하여 오이지의 적정 pH인 3.7을 오래 유지하므로써 적당한 산미를 계속 유지하였고, 대조군과 다른 부채료 첨가군에서는 숙성 14일째에 pH 3.5~pH 3.9에 도달하나 숙성 21일째에 다시 빠른 증가를 나타냈다. 2. 조직감 특성 Blossom end 부위에서는 백두웅이 증가하면 산초 5g 경우 시료 C, D에서 최고 hardness를 나타내는 저장기간이 길어지고, 산초 10g첨가군인 E, F, G에서는 백두웅 양 중가시 최고의 hardness를 나타내는 기간이 짧아졌다. Middle에서도 산초 5g첨가군에서는 B, C, 및 F처리군은 숙성 14일째, 시료 A, G에서는 7일째 높은 hardness를 나타냈고, 산초 10g을 첨가한 경우는 D, F처리군에서 최고의 hardness를 나타내어 산초 10g을 첨가할 경우 백두웅 양 증가시 최고 hardness에 이르는 기간이 짧아지는 경향을 나타냈다. Stem end 부위는 시료 A, B, C, F, G에서는 숙성 7일째, 시료 D처리군에서는 14일째, 시료 E처리군에서는 숙성 28일째 가장 높은 hardness를 나타냈다. 결과적으로 산초양이 적은경우(5g) 백두웅 양이 많아야(30g) 저장기간이 연장되며, 오히려 산초양이 많은 경우(10g)는 백두웅 양이 중가할 필요가 없고 어느재료를 얼마나 첨가할 것인지는 개인의 기호에 맞춰야 될것이며, 이는 앞으로 관능평가등의 방법을 통해 연구해 보는 것이 좋을 것이라 생각된다. 현재 결과로는 부재료 첨가시 (시료 C, D) 대조군보다 저장기간 중 완만한 hardness 변화를 나타내므로 저장성 연장에 효과가 있다고 본다. 3. 펙틱조성의 변화 3.1 AIS 함량의 변화 AIS는 숙성기간이 경과하면서 함량이 약간씩 감소함을 나타냈다. 산초 5g첨가군인 경우 백두웅 30g 첨가시 AIS 함량이 완만하게 감소했고, 산초 10g첨가군인 경우 백두웅 20g 첨가시 AIS 함량이 완만하게 감소했다. 3.2 HWSP함량의 변화 HWSP함량은 가용성 팩틴질의 함량을 보는 것으로 숙성됨에 따라 오이지가 연화되면서 그 함량이 증가한다. 산초 5g을 첨가한 경우는 백두웅 양이 증가함에 따라 HWSP 함량이 증가했고, 산초 10g첨가 군에서는 백두웅의 양이 증가하면 HWSP 함량이 E처리군이 F, G처리군보다 낮은 HWSP 함량을 나타냈다. 3.3 HXSP함량의 변화 대조군과 비교시 산초 5g첨가군에서는 백두웅 20g 첨가(시료 C)시 숙성 21일째까지도 높은 HXSP 함량을 보이며, 산초 10g첨가군에서는 백두웅 30g첨가군(시료 G)인 경우에는 28일째까지 높은 HXSP 함량을 나타냈다. 3.4 HCISP함량의 변화 HCISP는 대조군을 비롯하여 모든 부재료 첨가군에서 숙성기간에 따라 감소하였고, 산초 5g첨가군인 경우 백두웅 20g첨가군(시료 C)과 산초 10g첨가군인 경우 백두웅 10g첨가군이(시료 E) 완만히 감소하여 천천히 숙성되는 것으로 저장기간이 연장된다고 생각된다. 4. Hardness와 펙틴질 사이의 상관관계 팩틴물질의 함량과 조직감 측정과의 상관관계로 HCISP의 함량이 증가하면 hardness도 같이 증가하는가를 알아 보았다. 결과적으로 부재료 첨가군에서 대조군 보다 높은 유의성(p<0.001)의 양의 상관관계를 보여 hardness가 단단하면 HCISP 의 함량도 증가한다는 것을 나타냈다. This study was intended to observe the changes of pH, hardness, and pectic substances(AIS, HWSP, HXSP, HCISP) of Korean pickled cucumbers added Sancho and Backdooung to during fermentation for 6 weeks at 25℃. Changes of pH was decreased and later increased. Korean pickled cucumbers added Sancho 10g and Backdooung 10g maintained a sour taste for a long time. Control and minor ingredient treatments were reached pH 3.5~3.9 at 14th day of fermentation, but 21st day of fermentation fast increased. In blossom end, amount of Backdooung was increased ans Sancho 5g(C, D) showed hardness of maximum and period of storing became longer. Sancho 10g(E, F, G) showed hardness of maximum and period of storing shortens. In Middle, Sancho 5g(B, C) showed hardness of maximum at 14th day of fermentation, and Sancho 10g(D, E) showed hardness of maximum at 27th day of fermentation. A and D showed hardness of maximum at 7th day of fermentation. Minor ingredient treatments was longer than control in period of string. when Korean pickled cucumbers added Backdooung 10g to was reciprocal action to Sancho that was high significantly(p<0.001). Content of alcohol insoluble pectin(AIS), sodium hexametaphosphate soluble pectin(HXSP), and HCl soluble pectin(HCISP)were decreased, whereas content of hot water soluble pectin(HWSP) was increased during fermentation. In case of content of AIS, when Sancho 5g added, Backdooung 30G(C) was decreased gradully, and when Sancho 10g added, Backdooung 20g(F) was decreased gradually. Content of HWSP was increased when Sancho 5g added, as amount of Backdooung was increased. Control and Minor ingredient treatments were decreased during fermentation. this was the same as correlation between hardness and pectin substances.

난소 및 난소 종양 염전의 초음파 소견

오연희,이현경,이원재,이성우,박수성,윤혜원,임문환,심재철,김용탁,김성숙,김정란 동국대학교 경주대학 1993 東國論集 Vol.12 No.-

Acute torsion of the ovary and ovarian mass is a recognized surgical emergency, but rarely has the diagnosis been made preoperatively on the basis of imaging studies. The sonographic findings in 14 cases of surgically proven torsion of the ovary and ovarian mass are described. Mostly cystic ovarian mass, engorged vessel, dilated uterine tube, beak-like echo(torsion site), smooth mass wall thickening an free-fluid collection in cul-de-sac are described. More significant in terms of specificity were the demonstration in 6 cases(42.9%) of the smooth mass wall thickening and in 8 cases(57.1%) of a free fluid in the cul-de-sac. We report the sonographic findings of ovary and ovarian mass torsion that may suggest the preoperative diagnosis of this condition.

地黃의 품질평가

김남재,정은아,김희정,심상범,김종우 경희대학교 동서의학연구소 2001 東西醫學硏究所 論文集 Vol.2000 No.-

The dried roots of Rehmannia glutinosa(RG) have been used in the traditional medicine for treatment of diabetes, fever and dysuria, etc. In order to investigate the quality evaluation of the dried roots of RG, we conducted the physico-chemical and biological evaluation method. The amount of catalpol from commercial samples is very diverse about 0.00~3.89% by using HPLC method, because it is easily decomposed by processing of RG. So, we should try to identify the correlation with the contents of catalpol and biological activities of RG. We chose 3 samples which were a wide difference of catalpol contents between each sample(Sample-I; 3.4%, Sample-II; 2.8%, Sample-III; 0.05%). Sample-I and Sample-II were found to be more effective than Sample-III on the DPPH free radical scavenging effect and inhibitory effect on H₂O₂-catalyzed lipid peroxidation in rat liver in vitro. And, Sample-I and Sample-II exhibited more significant effects than Sample-III on accelerating actions of the small and large intestinal transport, and diuretic action in mice. So, it is suggested that the quantitative determination of catalpol should be required for the standardization of the dried roots of RG.

터어키안 상부에서 발생한 뇌수막종의 미세수술적 치료

한대희,정영섭,김봉수,정희원,조병규,최길수,심보성 대한신경외과학회 1986 Journal of Korean neurosurgical society Vol.15 No.1

Suprasellar meningiomas are uncommon intracranial tumors representing approximately 4-10% of intracranial meningiomas and the total excision is sometimes hazardous because of surrounding vital structures. We have experienced four cases of this lesion during last three years and the masses were approached through frontoparietal craniotomy and lateral subfrontal approach and were removed completely with microsurgical technique. Visual disturbances were improved in three cases and unchanged in one case. The literatures are also reviewed.

핍지신경교종 37예에 대한 임상적 연구

김하영,정희원,조병규,한대희,지제근,최길수,심보성 대한신경외과학회 1986 Journal of Korean neurosurgical society Vol.15 No.4

The authors reviewed 37 consecutive cases of histologically proven oligodendroglioma who were treated at the Seoul National University Hospital, between 1979 and 1986. There was a 1.5:1 male to female ratio. The age of patients at the time of diagnosis varied between 6 and 64 years(mean 38 years), with 51% in the fourth and fifth decades. The incidence of oligodendrogliomas represented 5% of all brain tumors and 15.5% of all gliomas. All but one were located supratentorially and 54% of them involved the frontal lobe. The mean duration of symptoms prior to the surgery was 27.2 months, but seizures had a considerably longer duration of 6.4 years. The common symptoms were headache(62%), seizures( 38%), and motor weakness( 22%). The common neurological findings were papilledema(51%), motor deficit(24%), and change in cognition(19%). Six out of 37 cases(16%) presented as the spontaneous intracranial hemorrhage. Calcifications were detected on plain X-ray films of the skull in 19% of patients and fine vascular stains were found on carotid angiograms in 30% of the cases. Brain CT revealed calcification(57%), cyst formation(43%),low density(35%) and heterogenous contrast enhancement (35%). The important factors affecting the prognosis and the recurrence rate were (1) the extent of surgical excision, (2) postoperative radiation therapy, and (3) the pathologic grading. There was a significant difference in the recurrence rate between patients treated with postoperative irradiation and patients treated with surgery alone.

자궁경부암 검사에서 Cotton swab 방법과 Cytobrush 채취방법에 의한 세포학적 진단 비교 분석 결과

선승철,이준기,양순희,박영심 한국건강관리협회 1998 건협 Report Vol.1 No.-