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강석진,이유영,고한중,전경문,노태희 한국초등과학교육학회 2004 초등과학교육 Vol.23 No.1
In this study, we investigated the effects of using concept mapping as an instructional tool on 4th graders' achievement, science learning motivation, and attitude toward science classes. T재 classes (38 students) from an elementary school were respectively assigned to a control group and a treatment group. Students were taught about "expansion of matter by heat" and "heat transfer". These topics were chosen because they require students to understand more concepts as well as relationships among them. A science learning motivation test and an attitude toward science classes test were administered as pretests. A researcher-made achievement test, the science learning motivation test, and the attitude toward science classes test were administered as posttests. The results indicated that using concept mapping in 4th-grade science classes was not significantly effective in improving students' achievement though a statistically significant positive effect was found in the subcategory of knowledge. No statistically significant effect of using concept mapping was found in the scores of the science learning motivation test and the attitude toward science classes test. Educational implications are discussed.
권순정,한정한,오은진,김석준,김노석,이특구 한국의료복지시설학회 2008 의료·복지 건축 Vol.14 No.3
The purpose of this study is to suggest optimum size of residents' bedrooms in nursing homes. Bedroom is an essential part of nursing homes because nursing home residents spend most of their times in bedrooms and occupy the largest part of facility area. Therefore it is necessary to set an adequate standard related to resident room area in nursing facilities, which have a great effect on planning longterm care facilities for the elderly. The body dimensions of elderly people and care givers have been collected from the previous study. Based on the body dimensions data, the behaviors of elderly as well as care givers have been analysed. The minimum areas-exclusive of toilets, closets, vestibules and so on - have been proposed from the results of the behavior analysis.
이영식,오강섭,노경선,김찬형,한진희,이민수 大韓神經精神醫學會 2003 신경정신의학 Vol.42 No.4
The Korean Neuropsychiatic Association (KNPA) was founded in 1945 and has now grown to over 2000 members as of 2003. The Association's academic meeting has also been increasing in size every year. To further develop the academic meeting of the KNPA, the task force team conducted this project. We suggest several points based on analysing the abstracts of the meeting that has conducted during the last 5 years, the survey results performed at the 2002 annual meeting, the annual meeting of the American Psychiatric Association, and the academic activities of a Korean medical assoction, the Korean Society of Otolaryngology.
Jin, Hyeon-Ok,Lee, Yun-Han,Park, Jin-Ah,Lee, Ha-Na,Kim, Jin-Hee,Kim, Ji-Young,Kim, BoRa,Hong, Sung-Eun,Kim, Hyun-Ah,Kim, Eun-Kyu,Noh, Woo Chul,Kim, Jong-Il,Chang, Yoon Hwan,Hong, Seok-Il,Hong, Young-J Springer-Verlag 2014 JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY Vol.140 No.12
<P>Piperlongumine (PL) has been shown to selectively induce apoptotic cell death in cancer cells via reactive oxygen species (ROS) accumulation. In this study, we characterized a molecular mechanism for PL-induced cell death.</P>
Han, Jin,Kim, Bokyoung,Shin, Jung-Youn,Ryu, Seungmi,Noh, Myungkyung,Woo, Jongsu,Park, Jin-Sil,Lee, Youjin,Lee, Nohyun,Hyeon, Taeghwan,Choi, Donghoon,Kim, Byung-Soo American Chemical Society 2015 ACS NANO Vol.9 No.3
<P>Electrophysiological phenotype development and paracrine action of mesenchymal stem cells (MSCs) are the critical factors that determine the therapeutic efficacy of MSCs for myocardial infarction (MI). In such respect, coculture of MSCs with cardiac cells has windowed a platform for cardiac priming of MSCs. Particularly, active gap junctional crosstalk of MSCs with cardiac cells in coculture has been known to play a major role in the MSC modification through coculture. Here, we report that iron oxide nanoparticles (IONPs) significantly augment the expression of connexin 43 (Cx43), a gap junction protein, of cardiomyoblasts (H9C2), which would be critical for gap junctional communication with MSCs in coculture for the generation of therapeutic potential-improved MSCs. MSCs cocultured with IONP-harboring H9C2 (cocultured MSCs: cMSCs) showed active cellular crosstalk with H9C2 and displayed significantly higher levels of electrophysiological cardiac biomarkers and a cardiac repair-favorable paracrine profile, both of which are responsible for MI repair. Accordingly, significantly improved animal survival and heart function were observed upon cMSC injection into rat MI models compared with the injection of unmodified MSCs. The present study highlights an application of IONPs in developing gap junctional crosstalk among the cells and generating cMSCs that exceeds the reparative potentials of conventional MSCs. On the basis of our finding, the potential application of IONPs can be extended in cell biology and stem cell-based therapies.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/ancac3/2015/ancac3.2015.9.issue-3/nn506732n/production/images/medium/nn-2014-06732n_0009.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nn506732n'>ACS Electronic Supporting Info</A></P>
Effect of structural distortion on ferrimagnetic order inLu1−xLxFe2O4(L=Yand Er;x=0.0, 0.1, and 0.5)
Noh, Han-Jin,Sung, Hojin,Jeong, Jinwon,Jeong, Jinhwan,Kim, Sung Baek,Kim, Jae-Young,Kim, J. Y.,Cho, B. K. American Physical Society 2010 Physical review. B, Condensed matter and materials Vol.82 No.2