서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

강원도 화천군 수달(Lutra lutra) 서식지의 식생 구조

서형수 ( Hyung Soo Seo ),신영섭 ( Young Seob Shin ),이경은 ( Kyung Eun Lee ),김윤미 ( Yoon Mi Kim ),전미나 ( Mina Jeon ),남택우 ( Taek Woo Nam ),한성용 ( Sung Yong Han ),정연숙 ( Yeonsook Choung ) 한국수생태학회 2014 생태와 환경 Vol.47 No.special

In order to determine whether vegetation would be one of the factors for the selection of otter home range, vegetation structure and other potential factors were studied in Hwacheon, Korea. Thirteen sites, otter’s activity found and not found, were investigated in North Han River and connected tributary streams of Hwacheon-gun. Three types of vegetation were classified by cluster analysis, which is short grass, tall grass and shrub type. Vegetation zone of each channel is composed of either one type, or mosaic of tall grass and shrub type. Short grass type is common in Lake Paro and upper North Han-river where water level is highly variable throughout a year. Therefore, annual species such as Persicaria nodosa, Fimbristylis dichotomam and Chenopodium ficifolium are the most dominant. Shrub type is common at the downstream sites of Jichon stream and along mainstream of North Han River down Lake Paro. A shrub species, Salix koreensis, is the most common. Tall grass type is dominant occupying the most vegetation zone of the tributary channels. Phragmites japonica is absolutely dominant. Due to its dense cover, a few plant species are co-existed. Otter activity was found in all three vegetation types and no marked activity was found at some sites of tall grass type. There is no difference in species composition and physiognomy between tall grass sites with and without otter activity, while it shows significant difference in fish availability between two groups. Overall we found that home range of otters in the region is along the mainstream and downstream of tributary streams with high fish availability in all vegetation types and in various human activity levels.

고관절 전치환술 후 발생한 재발성 탈구에 대한 대전자 부분 후하내방 이동술

성열보,한용택 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.5

In spite of great advancement in total hip arthroplasty, recurrent dislocation is stlll one of the most common complication after THA. There are two main treatment options for this complication. One is the component change and the other is soft tissue tightening which gives stability around the hip joint. For a case of recurrent dislocation after THA in a 68 year-old man, we tried partial postero-infero-medial transfer of greater trochanter-abductor unit which had an excellent result.

철원산 현무암을 이용한 결정화 유리 제조

한상목,신대용,이병민,木村邦夫 강원대학교 부설 석재복합신소재 제품연구센터 1999 석재연 논문집 Vol.4 No.-

철원산 현무암에 Al₂O₃와 CaO를 각각 첨가하여 결정화유리를 제조하고 그 물리적 특성을 조사하였다. SiO₂8.3wt%, CaO 20wt% 그리고 Al₂O₃8.3wt%를 현무암에 첨가하여 단일상의 Diopside 와 Anorthite를 제조할 수 있었으며, CaO를 첨가한 경우에는 첨가된 CaO가 결정핵으로 작용하여 anorthite와 diopside의 혼합 결정상이 얻어졌으며, Anothite는 CaO 첨가량이 증가함에 따라서 감소하는 경향을 나타내었다. Al₂O₃를 현무암에 첨가하면 hercynite(FeO·Al₂O₃)의 분해에 의해 anorthite가 생성되고 있음을 알 수 있었다. CaO 20wt% 첨가한 경우 900℃에서 2.93g/㎤의 부피 비중과 215MPa의 곡강도를 Al₂O₃ 8.3wt% 첨가한 경우에는 1000℃에서 2.83g/㎤과 210MPa의 곡강도를 나타내었다. 흡수율은 Al₂O₃8.3wt%, CaO 15wt% 그리고 Cao 20wt% 첨가한 경우 모두 900℃ 이상에서 1% 이하의 낮은 흡수율을 나타내었으며, 열팽창계수는 Diopside의 peak intensity가 증가함에 따라 증가하였다. Glass-ceramics were prepared by adding CaO 8.3wt%, 15wt%, 25wt% and Al₂O₃8.3wt% to SiO₂ 8.3wt% added Chulwon basalt and their effects of phase transition and firing temperature on the densification, microstructure development and thermal expansion coefficient were investigated by means of XRF. SEM and diletometer. It was one phase of diopside and anorthite respectively. The CaO added to Chulwon basalt played an role of crystal site of anorthite and diopside. However anorthite decreased and finally disappeared according as CaO addition increased by 20wt%. In case of decomposition. The flexural strength of CaO 20wt% added glass-ceramics fired at 900℃ and Al₂O₃ 8.3wt% added glass-ceramics fired at 1000℃ was 215MPa and 210MPa respectively. The thermal expansion coefficient varied from 6.554×??/℃ to 8.146×??/℃ depending on diopside peak intensity of CaO added glass-ceramics on XRD results.

대량의 각혈로 사망한 장티푸스 1예

한상우,유진홍,권순석,김성훈,박지찬,홍은정,최경성,박용완,장준희,안지원,박유경,강지영,박상미,신완식 대한감염학회 2004 감염과 화학요법 Vol.36 No.5

We experienced a 25 year-old male patient with typhoid fever complicated with massive hemoptysis. Pulmonary complication in typhoid fever is very rare and to our knowledge, there has been no report of hemoptysis as a main cause of death with this disease. We herein report a rare case of typhoid fever.

한국 재래산양에서 Bovine Viral Diarrhea, Bovine Herpesvirus-1, Parainfluenza Type-3 바이러스에 대한 혈청학적 연구

한동운,권용국,문진산,윤소라,위성환,장환,탁동섭,이태욱,강문일 한국수의공중보건학회 2003 예방수의학회지 Vol.27 No.3

The 948 goat sera were serologically tested for ten pathogens including bovine viral diarrhea (BVD), bovine herpes virus type-1 (BHV-1) and parainfluenza virus type-3 (PI-3). By viral neutralizaion test, three pathogens including BVD virus, BHV-1, PI-3 were applied for screening each neutralizing antibody and its titration. Among 948 sera, there were 215 seropositives (22.7%) against BVD virus, 25 (2.6%) against BHV-1 virus, and 161 (17.0%) against PI-3 virus, respectively. In the seropositive cases to BVD virus, provincial prevalence of them were recorded as Gyeongnam(30.8%) for the highest one, while as Jeonbuk (15.8%) and Gyeongbuk(l6.7%) relatively for the lower ones. Among them, higher than 1:8 in antibody titration was classified as 74 cases (34.4%) which were suspected the cycle of its infection in their herds. Among the seropositives to BHV-1, it was relatively lower prevalence rate ranging from 1.7% to 6.7% that those of BVD virus and PI-3, but more importantly they were prevailing across the country. Most of the seropositive cases (42.9%) to PI-3 were classified as 1:4-1:16 in titration, but also distributed all around the country. The prevalence in goats varied according to areas (15.8 to 30.8%). Related to the provincial prevalence of three viral agents in Korean goats, it seemed that three viral pathogens would be directly or indirectly involving in various disorders as primary or secondary causative agents resulting in decreased productivity.

재생 Al₂O₃분말을 이용한 Al₂O₃세라믹스의 소결 특성 연구

한상목,신대용 강원대학교 석재복합신소재제품연구센터 2001 석재연 논문집 Vol.6 No.-

Al2O3 세라믹스의 재활용을 위한 소결거동을 조사하기 위하여 재생 Al2O3 분말의 첨가량, 입자크기 및 소결온도에 따른 시편의 물리ㆍ기계적 특성을 측정하였다. 1,650℃에서 소결한 순수 Al2O3 시편을 급랭에 의하여 500㎛ 정도의 입자로 파쇄한 후, 자동유발을 이용하여 40㎛ 전ㆍ후로 분쇄하였다. 분쇄한 Al2O3 분말과 순수한 Al2O3 분말을 적정비로 혼합 후, 재소결에 의하여 제조한 Al2O3 세라믹스의 재생 Al2O3 분말의 첨가량, 입자 크기 및 소결온도에 따른 시편의 밀도 흡수율, 기공률, 3점곡강도 및 SEM 분석을 행하였다. 재생 Al2O3 분말의 첨가량이 증가함에 따라 시편 내에 존재한 기공에 의하여 밀도와 3점곡강도는 감소하였으나, 1,650℃에서 소결한 시편의 3점곡강도는 200 MPa 이상으로 구조용재료로 사용이 가능하였다. 또한, 재생 Al2O3 세라믹스 100wt%의 유리분말을 첨가하요 1,650℃에서 소결한 시편은 첨가한 유리분말의 고온용융에 의하여 생성한 액상에 의하여 물리ㆍ기계적 성질은 감소하였다. The sintering behavior of the Al2O3 composites for recycling Al2O3 powder was investigated as a function of the recycling Al2O3 powder and particle size with respect to physical and mechanical properties. Pure Al2O3 specimen was fabricated by sintering and was crushed into powder under 40㎛ in particle size by thermal shock treatment and automatic mortar crushing. Then, the crushed Al2O3 powder was mixed with pure Al2O3 powder, and the mixture was subjected to re-sintering to reuse Al2O3 composites. The reclaimed Al2O3 specimen were investigated by 3-point bending strength and SEM observation of microstructure. Density and 3-point bending strength of the reclaimed Al2O3 composites decreased as the addition amounts of recycled Al2O3 powder increased. The average 3-point bending strength of specimens heated at 1,650℃ were over 200 MPa. SEM observation indicated that pore distribution was inhomogeneous and pores were still resided in specimen, Pores, consequently, formed cracks which markedly decreased bending strength. Futhermore, 10wt% glass containing reused Al2O3 specimens were decreased physical and mechanical properties, so called over-sintering behavior.

뇌졸중과 동반된 병원감염

한범기,이지용,이성수,김헌주 연세대학교 원주의과대학 2000 원주의대논문집 Vol.13 No.1

한국산 뱀독이 개구리 심실근육세포의 수축력과 활동전압에 미치는 영향

한형일,방효원,엄대용,이상돈 중앙대학교 의과대학 의과학연구소 1984 中央醫大誌 Vol.9 No.3

In order to observe the effects of freeze-dried saliva of Agkistrodon caliginosus and Agkistrodon saxatilis, the Korean poisonous snakes, on the contractility and action potential of frog ventricular muscle cells, the isometric tension in a vertical chamber and the action potential in horizontal chamber were recorded and analyzed. The following results were obtained; 1. ED_50, to reduce the contractility was 4-8ug/ml in the case of A. saxatilis and 8-16ug/ml in the case of A. caliginosus which all were higher than that of A. brevicaudus and the inhibitory effect on the contractility was greater in the case of A. saxatilis than that of A. caliginosus. 2. In the case of A. saxatilis, APD_50(time to repolarize 50% of action potential amplitude) decreased from 820±80 ms to 710±60 ms, the overshoot and the V max(Maximum depolarization rate) decreased from 34±8 mV to 18±4 mV, from 98±8 V/s to 89±4 V/s respectively. 3. In the case of A. caliginosus, ADP_50 decreased from 880±70 ms to 720±40 ms, the overshoot and the V max decreased from 28±6 mV to 20±4 mV, from 89±8V/s to 77±12V/s, respectively. 4. Inhibition of contractility and overshoot potential were more prominent in A. saxatilis and APD_50 was more decreased in A. caliginosus. The above result showed that Korean snake venoms would decrease the ionic current underlying the rapid upstroke phase and slow inward currents by calcium ions simultaneously in a frog ventricular muscle cells.

직업적 연폭로에서 혈중 연량 수준에 따른 선별검사로서의 혈중 ZPP 검사의 타당도

한구석,안현철,김용배,리갑수,김화성,황규윤,장봉기,이성수,안규동,이병국 순천향대학교 산업의학연구소 1999 순천향산업의학 Vol.5 No.1

In order to evaluate the validity of current screening criteria of lead exposure and to provide effective information for the better health management of lead workers, author investigated the interrelationship between blood lead and blood zinc protoporphyrin(ZPP) and evaluate the validity of blood zinc protoporphyrin as the screening test and blood lead as gold standard of diagnostic test. The total of 2245 lead workers (male workers: 1982, female workers : 263) from 12 lead using industries were studied. Blood lead, ZPP, hemoglobin and hematocrit were selected as lead exposure variables. Personal information on sex, age and work duration were also checked. Blood lead was measured with flameless atomic absorption spectrometry (model: Hitachi 8100) using standard addition method. Blood ZPP was measured with portable hematoflurometer (model: Aviv 206). The results obtained were as follows: 1. The mean blood lead of all lead workers were 0.7±14.3㎍/㎗(Male: 31.0±14.4㎍/㎗, Female: 28.2±12.9㎍/㎗), whereas the mean blood ZPP of those were 68.1±47.5㎍/㎗(Male: 63.9±43.7㎍/㎗, Female: 100.1±61.0㎍/㎗). The mean value of hemoglobin and hematocrit of all lead workers were 14.5±1.5g/㎗(Male: 14.7±1.3g/㎗, Female: 12.3±1.2g/㎗) and 45.4±3.6(Male: 46.2±2.8, Female: 39.5±3.1) respectively. 2. Validity of test using blood zinc protoporphyrin as screening test for blood lead levels of 30㎍/㎗ as gold standard of diagnostic test revealed that the highest validity value for male and female lead workers were 50 and 90 ㎍/㎗ of ZPP respectively, showing 50 and 60 ㎍/㎗ of ZPP for all lead workers. While those test for blood lead levels of 40㎍/㎗ as gold standard of diagnostic test revealed that the highest validity value for male and female lead workers were 60 and 90 ㎍/㎗ of ZPP respectively, showing 60 ㎍/㎗ of ZPP for all lead workers, those test for blood lead levels of 50 and 60㎍/㎗ as gold standard of diagnostic test revealed that the highest validity value for male and female lead workers were 60 or 70 and 100 ㎍/㎗ ZPP respectively, showing 60and 70 or 80 ㎍/㎗ of ZPP for all lead workers. 3. Predictive value of test using blood zinc protoporphyrin as the screening test for different blood lead levels of 30, 40, 50 and 60㎍/㎗ as gold standard of diagnostic test revealed that positive predictive value of screening test were decreased by the increase of blood lead level regardless of csreening criteria value ZPP and negative predictive value of screening test were increased accordingly regardless of screening criteria value of ZPP. On the other hand, within same blood lead level as a gold standard positive predictive values were inceased by the increase of screening criteria value of ZPP, whereas the negative predictive value were decreased accordingly by the the increase of screening criteria value of ZPP. 4. The correlation analysis of all lead workers among study variables revealed that CPbB and natural log transformation ZPP(LZPP) were better correlated with other variables and found to be better estimate than PbB and ZPP themselves. The age was correlated with all other variables, but the work duration was not. The correlation analysis of male and female workers among study variables revealed the same results with all lead workers. 5. The slope of simple linear regression of CPbB (independent variable) with ZPP in female workers(3.223)was steeper than in male workers(2.144). That of lead workers with work duration of less than 1 year was steeper than that of lead workers whose work duration was more than 1 year. But there was no slope difference between two groups divided by their work duration of 2 years less and more. The slope of simple linear regression of CPbB lead (independent variable)with ZPP in lead workers whose blood lead were higher than 30㎍/㎗and 40㎍/㎗ were steeper than those whose blood lead were less than 30㎍/㎗ and 40㎍/㎗. 6. The slope of simple linear regression of CPbB (independent variable) with ZPP in lead industries with low mean blood lead were less steeper than those with high mean blood lead. 7. The slope of simple linear regression of CPbB (independent variable) with LZPP in female workers(0.0308was steeper than in male workers(0.0253). That of lead workers with work duration of less than 1 year was steeper than that of lead workers whose work duration was more than 1 year. But where was no slope difference between two groups divided by their work duration of 2 years less and more. While the slope of simple linear regression of CPbB lead (independent variable) with LZPP in lead workers whose blood lead were hogher than 30㎍/㎗ was not steeper than those whose blood lead were less than 30㎍/㎗, there was no slope difference between two groups whose blood lead were less than 40㎍/㎗ and more than 40㎍/㎗. 8. The slope of simple linear regression of CPbB (independent variable) with LZPP in lead industries with low mean blood lead were less steeper than those with high mean blood lead, but the difference was not significant then that of CPbB and ZPP. With above results, it is recommended that the screening criteria value of ZPP should be down to 60-70㎍/㎗ from 100㎍/㎗ for male lead workers and screening criteria of ZPP for female lead workers was all right with current value of 100㎍/㎗. So it is recommended to make different screening criteria of ZPP for male and female workers like the hemoglobin and hematocrit screening criteria. It is also preferable to use CPbB and LZPP rather than uncorrected PbB and ZPP in the evaluation of lead exposure for lead workers.