정신보건관련시설 입원(소)자의 주요 정신장애 유병률 : 전국 20개 시설의 입원(소)자를 대상으로

조성진,조맹제,서동우,함봉진,홍진표,배재남,이준영,이동우,박종익,전홍진,김성주,김용익 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.6

Objectives : One of the objectives of this study is to estimate the prevalence rates of psychiatric diagnoses in the combined populations of psychiatric hospitals, psychiatric nursing facilities and homeless asylums using the Korean version of the Composite International Diagnostic Interview (K-CIDI), which is a comprehensive and fully standardized interview schedule to assess psychiatric disorders for diagnosis. The Other objective is to compare with previously studied prevalence rates of Psy-chiatric diagnoses using the results of this study. Methods : The study subjects, aged from 181o 64 years, were randomly selected from 64,582 institutionalized population of psychiatric hospitals, Psychiatric nursing facilities and homeless asylums as of 30, June, 2001. Twelve trained interviewers administered the K-CIDI to the selected respondents. A total of 1,875 respondents (male 1,194, female 681) completed the interview. Results : The lifetime and one year prevalences of any diagnosis excluding nicotine dependence · withdrawal, anxiety disorder, eating disorder, somatoform disorder were 88.2% (male 88.1%, female 88.3%), and 65.8% (male 62.7%, female 73.7%), respectively. The lifetime and one year prevalences of schizophrenia and other psychotic disorders were 78.5% (male 75.3%, female 83.7%), and 56.8% (male 51.9%, female 64.8%), respectively. The lifetime and one year prevalences of alcohol use disorder (dependence/abuse) were 26.7% (male 37.9%, female 8.3%), and 8.7% (male 12.8%, female 2.1%), respectively. The lifetime and one year prevalences of mood disorder were 18.1% (male 13.5%, female 25.8%), and 10.4% (male 7.2%,female 16.9%), respectively. The lifetime and one year prevalences of schizophrenia and other psychotic disorders were comparable with the 2001 community survey by 1.19% to 1.32%, and 0.51% to 0.61%, respectively. The lifetime and one year prevalences of schizophrenia were also comparable by 0.16% to 0.28%, and 0.16% to 0.25%, respectively. There were no significant changes of prevalence rates when correction were applied to other psychiatric diagnosis. Conclusion : The results of this study could be used for evaluating the distribution of psychiatric diagnoses in mental health related facilities and for planning mental health policies.

한국 정신장애의 역학 조사 연구[I] : 각 정신장애의 유병률

조맹제,함봉진,김장규,박강규,정은기,서동우,김선욱,조성진,이준영,홍진표,최용성,박종익,이동우,이기철,배재남,신정호,정인원,박종한,배안,이충경 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.4

Objectives : This study aims to estimate the prevalence of the DSM-IV psychiatric disorders in Korean population using the Korean version of Composite International Diagnostic Interview (K-CIDI). Methods : Subjects were selected by taking multi-stage, cluster samples of 7,867 adult household residents, 18 to 64 years of age, in ten catchment areas. Total 78 trained interviewers administered the K-CIDI to the selected respondents, from June 1 to November30,2001. Results : Total 6,275 respondents completed the interview. Some 33.5% of respondents reported at least one lifetime disorder, 20.6% reported at least one-year disorder, and 16.7% reported at least one-month disorder. The most common lifetime disorders were alcohol abuse/dependence (17.24%), nicotine dependence/withdrawal (11.19%), specific phobia (5.16%), and major de-pressive disorder (4.25%). The lifetime prevalence of substance abuse/dependence (0.25%) and schizophrenia (0.16%) was very low. Nicotine and alcohol use disorder showed very high male/female ratio. Mood disorder and anxiety disorder were more prevalent among female than male. Conclusion : The prevalence of psychiatric disorders was high. In comparison with other studies, remarkable differences in distributions of psychiatric disorders across the areas and times were observed.

한국어 판 구조화 임상면담도구 개발 : 신뢰도 연구

한오수,안준호,송선희,조맹제,김장규,배재남,조성진,정범수,서동우,함봉진,이동우,박종익,홍진표 대한신경정신의학회 2000 신경정신의학 Vol.39 No.2

연구목적: 정신장애의 정확한 진단과 평가는 임상에서뿐만 아니라 신뢰성 있는 연구를 위해서도 매우 중요하다. Structured Clinical Interview for DSM-IV(SCID)는 임상전문가들이 사용하는 진단도구로서, 비교적 짧은 시간에 정확한 진단을 내릴 수 있다. 본 연구는 한국어판SCID를 개발하고 그 신뢰도를 평가하기 위해 수행되었다. 방법: 국문학자가 포함된 번역위원회를 통하여 연구용판 SCID를 번역한 후, 정신과 의사 2인과 임상심리학자 1인에게 한국어판SCID 실시방법을 교육시킨 뒤 한국어판SCID를 이용한 면담의 평가자간 신뢰도 (interrater reliability)를 검증하였다. 면담 대상은 1999년 2월에서 3월까지 2개 병원 정신과에 치료중인 환자 90명(남:41명, 여:29명)이었다. 결과: 현재 장애(current disorder) 평가에서 주요 우울장애, 기분부전장애, 정신분열병, 알코올 남용 및 의존, 기타 물질 남용 또는 의존, 여러 불안장애들 및 섭식장애 등과 같은 대부분 장애의 kappa값은 .70이상으로 매우 높았다. 그 이외의 양극성 장애, 망상장애, 광장공포증, 감별 불능 신체화 장애 및 건강염려증의 kappa값도 .69에서 .40사이로 수용할 수 있는 정도였다. 평생 장애(lifetime disorder)에서는 양극성 장애(k=.69)와 감별 불능 신체화장애(k=.59)를 제외한 다른 모든 장애의 kappa값이 .70이상이었다. K-SCID 면담시 Ⅰ축 질환에 대하여 흔하게 다중 진단이 내려졌으며, 평균 진단 수는 1.5∼1.7개로 나타났다. 결론: 한국어판 SCID는 신뢰도가 높은 진단도구로 생각되며, 향후 정신질환의 정확한 진단과 임상연구에 유용하게 사용될 수 있다. Objectives: Accurate diagnosis and assessment for psychiatric disorders is crucial for research, as well as for clinical practice. Structured Clinical Interview for DSM-Ⅳ(SCID-RV) is a less time-consumimg and more accurate structured diagnostic interview form. It can be used by clinical professions and is known for a reliable diagnostic tool. Present study was conducted to develop Korean version of SCID-RV and to test the inter-rater reliability. Methods: The authors have translated original SCID-RV into Korean, and revised in parallel with sociocultural background of Korea. Ninety patients from two psychiatric hospitals, both outpatient and inpatient, were interviewed and rated independently by three raters. Results: The kappa coefficients for most of illnesses, such as major depressive disorder, dysthymia, schizophrenia, alcohol abuse and dependency, anxiety disorder and eating disorder were excellent(>0.70) in the evaluation of current disorders. And the kappa coefficients for bipolar disorder, delusional disorder, agoraphobia, undifferentiated somatoform disorder, and hypochondriasis were acceptable(>0.40) in the evaluation of current disorders. In the evalua-tion of lifetime disorders, the concordant rates of all the diagnoses except bipolar disorder and undifferentiated somatoform disorder were excellent. Lack of hierarchy in DSM-Ⅳ allows for multiple Axis I diagnoses. Mean numbers of Axis I diagnoses per subject assigned by the three raters were 1.5-1.7. Conclusions: Our findings confirm that SCID-RV yields highly reliable diagnoses. SCID-RV is recommended for accurate diagnosis in clinical practice and research on psychiatric disorders.

한국 주요정신장애의 유병률 및 관련요인 : 2006 전국정신질환역학조사

조맹제,장성만,함봉진,정인원,배안,이영문,안준호,원승희,손정우,홍진표,배재남,이동우,조성진,박종익,이준영,김진영,전홍진,이해우 大韓神經精神醫學會 2009 신경정신의학 Vol.48 No.3

Objectives The aims of this study are to estimate the prevalence of the DSM-IV psychiatric disorders in the Korean population using the Korean version of Composite International Diagnostic Interview (K-CIDI), and to compare those with previous studies. Methods The Korean Epidemiologic Catchment Area study Replication (KECA-R) was Conducted between August 2006 and April 2007. The sampling of the subjects was carried out across 12 catchment areas. A multistage, cluster sampling design was adopted. The target Population included all eligible residents aged 181o 64 years. Face-to-face interviews were conducted with the Korean version of Composite International Diagnostic Interview (K-CIDI) based on the DSM-IV (N=6,510, response rate=81.7%). Results A total of 6,510 participants completed the interview. The lifetime and 12-month prevalence rates for all types of DSM-IV disorders were 30.0% and 17.3%, respectively. Those of Specific disorders were as follows : 1) alcohol use disorder, 16.2% and 5.6% ; 2) nicotine use disorder, 9.0% and 6.0% ; 3) specific phobia, 3.8% and 3.4% ; 4) major depressive disorder, 5.6% and 2.5% ; and 5) generalized anxiety disorder, 1.6% and 0.8%. Data relating to nicotine and alcohol use disorder revealed a very high male/female ratio. Mood disorder and anxiety disorder were more prevalent among females than males. Conclusion The prevalence of psychiatric disorders was high. In comparison with other studies, remarkable differences in the distribution of psychiatric disorders across the country and times were observed.

GMM 기반의 문맥독립 화자 검증 시스템의 성능 향상을 위한 유사도 변환 정규화 방법

함성준(Seong-Jun Hahm),양경진(Kyung-Jin Yang),신광호(Guang-Hu Shen),김주곤(Joo-Gon Kim),정현열(Hyun-Yeol Chung) 한국정보과학회 영남지부 2004 한국정보과학회 영남지부 학술발표논문집 Vol.12 No.1

본 논문에서는 GMM(Gaussian Mixture Model)을 이용한 문맥독립 화자 검증 시스템을 구현한 후, 여러 가지 기존의 정규화 방법과 arctan 함수를 이용한 제안된 정규화 방법을 사용하여 화자검증실험을 수행하였다. 특정파라미터로서는 선형예측방법을 이용한 켑스트럼 계수와 회귀계수를 사용하고 화자의 발성 변이를 고려하여 CMN(Cepstral Mean Normalization)을 적용하였다. 화자모델 생성을 위한 학습단에서는 화자발성의 음향학적 특징을 잘 표현할 수 있는 GMM(Gaussian Mixture Model)을 이용하였고 화자 검증단에서는 ML(Maximum Likelihood)을 이용하여 유사도를 계산하고 기존의 정규화 방법과 arctan 함수를 이용한 방법에 의해 정규화된 점수 (score)와 미리 정해진 문턱 값과 비교하여 검증실험을 수행하였다. 화자 검증 실험결과, arctan 함수를 이용한 방법이 기존의 방법보다 향상된 EER을 나타냄을 확인할 수 있었다.

Remote API 기반의 고성능 GPU 클라우드 시스템 성능분석

전태준(TaeJoon Jun),유명환(Myong Hwan Yoo),Van Quoc Dung,김성훈(Seong Hoon Kim),김대영(Daeyoung Kim),조혜영(HyeYoung Cho),함재균(Jaegyoon Hahm) 한국정보과학회 2014 한국정보과학회 학술발표논문집 Vol.2014 No.6

Poster Session 1 : oral Presentation ; Structural Basis of Protein Function and Regulation : Mechanism of action of novel HP (2-20) analogue peptide: tryptophan-substitution changed the characteristics of amphipathic α-helical peptide

( Yoon Kyung Park ),( Seong Cheol Park ),( Jun Young Kim ),( Mi Hyun Kim ),( Soon Nang Park ),( Sun Oh Shin ),( Kang Won Cheong ),( Kyung Soo Hahm ) 생화학분자생물학회 2005 62회 KSBMB Annual Meeting in 2005 Vol.- No.-

화자 검증 시스템을 위한 PCA 기반 MFDWC 특징 파라미터

함성준,정호열,정현열,Hahm Seong-Jun,Jung Ho-Youl,Chung Hyun-Yeol 한국음향학회 2006 韓國音響學會誌 Vol.25 No.1

A Principal component analysis (PCA)-based Mel-Frequency Discrete Wavelet Coefficients (MFDWC) feature Parameters for speaker verification system is Presented in this Paper In this method, we used the 1st-eigenvector obtained from PCA to calculate the energy of each node of level that was approximated by. met-scale. This eigenvector satisfies the constraint of general weighting function that the squared sum of each component of weighting function is unity and is considered to represent speaker's characteristic closely because the 1st-eigenvector of each speaker is fairly different from the others. For verification. we used Universal Background Model (UBM) approach that compares claimed speaker s model with UBM on frame-level. We performed experiments to test the effectiveness of PCA-based parameter and found that our Proposed Parameters could obtain improved average Performance of $0.80\%$compared to MFCC. $5.14\%$ to LPCC and 6.69 to existing MFDWC. 본 논문에서는 화자검증 시스템의 성능향상을 위해서 주성분 분석 (PCA) 기반 Mel-Frequency Discrete Wavelet Coefficients (MFDWC) 추출방법을 제안한다. 제안된 방법에서는 멜척도 (Mel-scale)를 근사화한 각 레벨 (level)의 각 노드 (node) 에너지를 계산하기 위해 기존의 평균치 대신 주성분 분석을 이용한 첫 번째 eigenvector를 이용한다. 이 eigenvecto.의 제곱의 합은 1로서 일반적인 가중 함수 (weighting function)의 조건을 만족하고, 또한 각 화자마다 서로 다른 값을 갖게 되므로, 화자의 특징을 더 잘 나타내는 MFDWC를 추출할 수 있다. 화자검증은 Gaussian Mixture Model (GMM) 기반의 백그라운드 모델과 화자 모델과의 점수를 비교하는 이진 결정 (binary decision) 방법을 이용하여 Universal 백그라운드 모델 (UBM)과 각 화자 모델의 값을 프레임단위로 비교하여 대상 화자의 수락/거부 여부를 결정하는 방법을 채택하였다. 특징 파라미터에 따른 화자 검증 성능변화를 확인하기 위하여 제안된 화자종속 가중함수를 이용한 MFDWC를 특징 파라미터로 이용한 경우와 Mel-Frequency Cepstral Coefficients (MFCC), Linear Predictive Cepstral Coefficients (LPCC), 기존의 MFDWC를 특징 파라미터로 이용한 경우에 대하여 성능비교실험을 수행한 결과 각각 $0.80\%,\;5.14\%,\; 6.69\%$의 향상된 성능을 나타내어 제안한 방법의 유효성을 확인할 수 있었다.

정보품질 향상으로 인한 조직성과와 조직에 대한 사용자의 인식과의 차이에 관한 연구

김본영 ( Bom Young Kim ),이석준 ( Seong Jun Lee ),함유근 ( Yu Kun Hahm ) 한국정보시스템학회 2012 情報시스템硏究 Vol.21 No.2

In the field of education in Korea, University Information Disclosure System was conducted forcibly in December 2008 by Ministry of Education, Science and Technology. As a result, information quality provided to the user has been improved dramatically. Based on the preceding studies of information success model, the purpose of this study was to prove empirically three facts on the organization`s performance, user`s attitude, and gaps between two factors by improvement in the quality of information. To accomplish the purpose, literature review and statistical analysis were done using the university evaluation data published by JoongAng Daily from 2007 to 2011. The results of this study showed that the information quality had positive effect on organization`s performance, user`s attitude like a reputation, and the gaps between two factors. The results of this study had a great expectation for the role of offering useful insight and information in the field of information system and education.

환자들의 정보요구가 e-Health 시스템 사용과 성과에 미치는 영향에 관한 연구: 유방암환자대상 수요자의료정보시스템을 중심으로

박성식 ( Sung Sik Park ),이석준 ( Seong Jun Lee ),함유근 ( Yu Keun Hahm ) 한국정보시스템학회 2013 情報시스템硏究 Vol.22 No.2

Recently, since the interest with well-being has been getting higher than ever, people want reliable source of information related with health and medical treatment. Because of the characteristics of information related with medical care, there have been difficulties to find the information from books, television and internet surfing, for treating disease. Misinformation that can be obtained when considering dangerous situations or side effects, the role of the e-Health system is becoming more important. The objective of this study is an analysis of correlation and effect among patient`s information need, e-Health system use and system outcome. To achieve the object of this study, e-Health system had been given to patients of breast cancer in Wisconsin and Detroit for 16 weeks. As a result, 282 sample was gathered and modified to meet purpose of the study. As a result, the information needs of patients due to the performance of the e-Health systems and shown to affect even the perception of patients` emotional and physical health and social support.