Firework Plots for Evaluating the lmpact of Outliers and lnfluential Observations in Generalized Linear Models

( Dae Heung Jang ),( Cahristinem. Anderson Cook ) 한국품질경영학회 2014 한국품질경영학회 학술대회 Vol.2014 No.2

Outliers can distort many measures in data analysis and statistical modeling, and influential points can have disproportionate impact on the estimated values of model parameters. Jang and Anderson-Cook [1] proposed a new set of graphical summaries, called firework plots, as simple tools for evaluating the impact of outliers and influential points in regression. Variations of the plots focus on allowing visualization of the impact on the estimated parameters and variability. In the generalized linear models analysis setting, the impact of changing model parameters is often less transparent than in the linear model setting and variability can be captured with the deviance. Hence, this paper describes how 3-D firework plots and the pairwise firework plot matrix can be used to increase understanding of contributions of individual observations and as a complement to other regression diagnostics techniques in the generalized linear models setting. Using these firework plots, we can find outliers and influential points and their impact on model parameters. We illustrate the information and understanding gain possible with several examples.

Competing Views on Law and Adjudication in Canada: The Black-Letter Law Tradition versus Contextualism

Bruce Anderson(Bruce Anderson ) 한국캐나다학회 2003 Asia-Pacific Journal of Canadian Studies (APJCS) Vol.9 No.-

Proteomic Analysis of the GacA Response Regulator in Pseudomonas chlororaphis O6

Anderson, Anne J.,Kim, Young Cheol The Korean Society of Plant Pathology 2018 식물병연구 Vol.24 No.2

The GacS/GacA system in the root colonizer Pseudomonas chlororaphis O6 is a key regulatory system of many traits relevant to the plant probiotic nature of this bacterium. The work in this paper elucidates proteins using proteomics approach in P. chlororaphis O6 under the control of the cytoplasmic regulatory protein, GacA. A gacA mutant of P. chlororaphis O6 showed loss in production of phenazines, acyl homoserine lactones, hydrogen cyanide, and protease, changes that were associated with reduced in vitro antifungal activity against plant fungal pathogens. Production of iron-chelating siderophore was significantly enhanced in the gacA mutant, also paralleling changes in a gacS mutant. However, proteomic analysis revealed proteins (13 downregulated and 7 upregulated proteins in the mutant compared to parental strain) under GacA control that were not apparent by a proteomic study of a gacS mutant. The putative identity of the downregulated proteins suggested that a gacA mutant would have altered transport potentials. Notable would be a predicted loss of type-VI secretion and PEP-dependent transport. Study of mutants of these GacA-regulated proteins will indicate further the features required for probiotic potential in this rhizobacterium.

The Power of Being Small: Nanosized Products for Agriculture

Anderson, Anne J. The Korean Society of Plant Pathology 2018 식물병연구 Vol.24 No.2

Certain agrochemicals may be tuned for increased effectiveness when downsized to nanoparticles (NPs), where one dimension is less than 100 nm. The NPs may function as fertilizers, pesticides and products to improve plant health through seed priming, growth promotion, and induction of systemic tolerance to stress. Formulations will allow targeted applications with timed release, reducing waste and pollution when compared to treatments with bulk-size products. The NPs may be a single component, such as nano-ZnO as a fertilizer, or be composites of compatible materials, for example where N, P, and K plus micronutrients are available. The active materials could be loaded into porous carriers or tethered to base nanostructures. Coatings could include such natural products alginate, chitosan, zein, or silica. Certain NPs are taken up and transported in the plant's phloem and xylem so systemic effects are feasible. Timed and targeted release of the active product could be achieved in response to changes in pH or availability of ligands within the plant or the rhizosphere. Global research has revealed the many potentials offered by NP formulations to aid sustainability in agriculture. Current work will provide information needed by regulatory agencies to assess their safety in the agricultural setting.

Bioactive Properties of Murici (Byrsonima crassifolia) and Bacuri (Platonia insignis) and Their Antioxidant and Anti-Inflammatory Effects in Rats

Anderson Junger Teodoro,Cassiano Felippe Gonçalves-de- Albuquerque,Raquel Martins Martinez,Audrey Cristina Cintra,Carolina de Oliveira Ramos Petra de Almeida,Thuane Passos Barbosa Lima,Isabelle Moraes 한국식품영양과학회 2025 Journal of medicinal food Vol.28 No.5

Fruit consumption favors energy balance, ensures essential nutrients, and provides bioactive compounds withantioxidant and anti-inflammatory activities capable of preventing and treating noncommunicable diseases. TremendousBrazilian biodiversity favors countless fruit and vegetable crops, including exotic fruits. This study aimed to describe thenutritional characteristics of murici and bacuri and their effects on oxidative stress and inflammation. The murici lyophilizedextract (MLE) and bacuri lyophilized extract (BLE) were evaluated for their antioxidant activity and total phenolic compoundscontent. Healthy female Wistar rats were divided into control and supplemented groups (50, 100, and 250 mg/kgbody weight) for each fruit, with a 14-day supplementation. Parameters of oxidative damage and antioxidant system inplasma and inflammatory biomarkers in the kidney and liver tissues were evaluated. Murici has carotenoids as the main bioactivecompound, whereas bacuri is a source of polyphenols, with relevant antioxidant activity for human health. Treatmentwith MLE in healthy rats resulted in increased plasma antioxidant capacity measured by DPPH assay, reduced plasma levelsof lipid peroxidation (TBARS) and carbonylated proteins, and lower TNF-a production in the kidney and liver. BLE supplementationreduced plasma lipid peroxidation levels and led to lower activity of IL-1 b, IL-6, and TNF-a in supplementedanimals’ kidneys. Both fruits showed positive antioxidant and anti-inflammatory effects against oxidative stress and inflammationin an in vivo model. The results point to new antioxidant and anti-inflammatory resources to be studied.

The Gac/Rsm Signaling Pathway of a Biocontrol Bacterium, Pseudomonas chlororaphis O6

Anderson, Anne J.,Kang, Beom Ryong,Kim, Young Cheol The Korean Society of Plant Pathology 2017 식물병연구 Vol.23 No.3

Pseudomonas chlororaphis O6, isolated from the roots of dryland, field-grown commercial wheat in the USA, enhances plant health and therefore it is used in agriculture as a biofertilizer and biocontrol agent. The metabolites produced by this pseudomonad stimulate plant growth through direct antagonism of pathogens and by inducing systemic resistance in the plant. Studies upon P. chlororaphis O6 identify the pathways through which defined bacterial metabolites generate protection against pathogenic microbes, insects, and nematodes. P. chlororaphis O6 also triggers plant resistance to drought and salinity stresses. The beneficial determinants are produced from bacterial cells as they form biofilms during root colonization. Molecular control these processes in P. chlororaphis O6 involves the global regulatory Gac/Rsm signaling cascade with cross-talk between other global regulatory pathways. The Gac/Rsm regulon allows for coordinate phasing of expression of the genes that encode these beneficial traits among a community of cells. This review provides insights on the Gac/Rsm regulon in expression of beneficial traits of the P. chlororaphis O6 which can contribute to help yield enhancement and quality in agricultural production.

Immunization

Anderson, Donald C.,Stiehm, E. Richard MediMedia Korea 1993 JAMA-Korea Vol.8 No.4

藥物과 授乳 (完)

Anderson, Philip o.,南宮鳳 藥業新聞社 1978 醫藥情報 Vol.1978 No.3

Almost splitting sets in integral domains, II

Anderson, David F.,Chang, Gyu Whan North-Holland Pub. Co 2007 Journal of pure and applied algebra Vol.208 No.1

<P><B>Abstract</B></P><P>Let D be an integral domain. A saturated multiplicative subset S of D is an <I>almost splitting set</I> if, for each 0≠d∈D, there exists a positive integer n=n(d) such that <SUP>dn</SUP>=st for some s∈S and t∈D which is v-coprime to each element of S. We show that every upper to zero in D[X] contains a primary element if and only if D∖{0} is an almost splitting set in D[X], if and only if D is a UMT-domain and Cl(D[X]) is torsion. We also prove that D[X] is an almost GCD-domain if and only if D is an almost GCD-domain and Cl(D[X]) is torsion. Using this result, we construct an integral domain D such that Cl(D) is torsion, but Cl(D[X]) is not torsion.</P>

Laser ablation of via holes in GaN and AlGaN∕GaN high electron mobility transistor structures

Anderson, Travis,Ren, Fan,Pearton, Stephen J.,Mastro, Michael A.,Holm, Ron T.,Henry, Rich L.,Eddy, Charles R.,Lee, Joon Yeob,Lee, Kwan-Young,Kim, Jihyun American Vacuum Society 2006 JOURNAL OF VACUUM SCIENCE & TECHNOLOGY B - Vol.24 No.5