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원발성 담즙성 경변증 16예의 임상상 : 단일 센터 경험
박동일(Dong Il Park),고광철(Kwang Cheol Koh),이준혁(Jun Hyek Lee),최문석(Moon Seok Choi),강태욱(Tae Wook Kang),문원(Won Moon),류민규(Min Kyoo Ryu),이용욱(Yong Wook Lee),김지은(Jee Eun Kim),현재근(Jae Geun Hyun),장재권(Jae Kwon Jang) 대한내과학회 2000 대한내과학회지 Vol.59 No.6
N/A Background : Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disease of unknown etiology. The disease is relatively common in western countries, but so far, only about 20 cases have been reported in Korea. Thus, the purpose of our prospective study was to evaluate the clinical characteristics of PBC in Korea. Methods : Between October 1994 and February 1999, 16 patients diagnosed as PBC at our department were enrolled in this study. We analyzed these patients for the distribution of age and sex, initial symptoms and signs, associated disorders, laboratory, endoscopic, and radiologic and histologic findings. Results : Of the 16 patients, the ratio of male to female was 1:7 and the average age was 57.5 years. Pruritus (37.5%) was the most frequent presenting symptom followed by xerostomia and xerophthalmia (12.5%), jaundice (6.3%), chronic fatigue (6.3%), melena (6.3%). Associated disorders were Sj gren's syndrome (25%), arthropathy (12.5%), Raynaud's phenomenon (6.3%) and diabetes (6.3%). Abnormalities of liver function were found frequently. Antimitochondrial antibody (100%), antinuclear antibody (31.25%) and rheumatoid factor (31.25%) were found. Long-term administration of UDCA improved both clinical and biochemical signs in most patients, however, 2 patients experienced exacerbation during UDCA therapy. Conclusions : We experienced 16 cases of PBC within a short period. It is expected that we can find these patients more frequently if we suspect this disease in patients with pruritus and unexplained obstructive pattern of liver function abnormality.(Korean. J. Med 59:634-640, 2000)
분산공유 메모리 시스템을 위한 동적 제한 디렉터리 기법
이동광(Lee Dong Kwang),권혁성(Kweon Hyek Seong),최성민(Choi Seong Min),안병철(Ahn Byoung Chul) 한국정보처리학회 1999 정보처리학회논문지 Vol.6 No.4
The caches in distributed shared memory systems enhance the performance by reducing memory access latency and communication overhead, but they must solve the cache coherence problem. This paper proposes a new directory protocol to solve the cache coherence problem and to improve the system performance in distributed shared memory systems. To maintain the cache coherence of shared data, processors within a limited distance reduce the communication overhead by using a bit-vector like the full directory scheme. Processors over a limited distance store pointers in a directory pool. Since the bit-vector and the directory pool remove the unnecessary cache invalidations, the proposed scheme reduces the communication traffic and improves the system performance. The dynamic limited directory scheme reduces the communication traffic up to 66 percents compared with the limited directory scheme and the number of directory access up to 27 percents compared with the dynamic pointer allocation scheme.