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Chun-Xia Fan,Fuwen Yang,Ying Zhou 제어·로봇·시스템학회 2012 International Journal of Control, Automation, and Vol.10 No.3
A state estimation problem is studied for a class of coupled outputs discrete-time networks with stochastic measurements, i.e., the measurements are missing and disturbed with stochastic noise. The considered networks are coupled with outputs rather than states, are coupled with different inner coupling matrices rather than identical inner ones. By using Lyapunov stability theory combined with stochastic analysis, a novel state estimation scheme is proposed to estimate the states of discrete-time complex networks through the available output measurements, where the measurements are stochastic missing and are disturbed with Brownian motions which are caused by data transmission among nodes due to communication unreliability. State estimation conditions are derived in terms of linear matrix inequalities (LMIs). A numerical example is provided to demonstrate the validity of the proposed scheme.
( Chun Fang ),( Tong Cao ),( Ying Shan ),( Ye Xia ),( Yong Ping Xin ),( Chang Yong Cheng ),( Houhui Song ),( John Bowman ),( Xiao Liang Li ),( Xiang Yang Zhou ),( Wei Huan Fang ) 한국미생물 · 생명공학회 2016 Journal of microbiology and biotechnology Vol.26 No.1
Listeria monocytogenes is a foodborne pathogen of considerable genetic diversity with varying pathogenicity. Initially, we found that the strain M7 was far less pathogenic than the strain Lm850658 though both are serovar 4a strains belonging to the lineage III. Comparative genomic approaches were then attempted to decipher the genetic basis that might govern the strain-dependent pathotypes. There are 2,761 coding sequences of 100% nucleotide identity between the two strains, accounting for 95.7% of the total genes in Lm850658 and 92.7% in M7. Lm850658 contains 33 specific genes, including a novel 20K prophage whereas strain M7 has 130 specific genes, including two large prophages (38K and 44K). To examine the roles of these specific prophages in pathogenicity, the 20K and 38K prophages were deleted from their respective strains. There were virtually no differences of pathogenicity between the deletion mutants and their parent strains, although some putative virulent factors like VirB4 are present in the 20K region or holin-lysin in the 38K region. In silico PCR analysis of 29 listeria genomes show that only strain SLCC2540 has the same 18 bp integration hotspot as Lm850658, whereas the sequence identity of their 20K prophages is very low (21.3%). The 38K and 44K prophages are located in two other different hotspots and are conserved in low virulent strains M7, HCC23, and L99. In conclusion, the 20K and 38K prophages of L. monocytogenes serovar 4a strains Lm850658 and M7 are not related to virulence but contribute to genetic diversity.
RELATION BETWEEN DEMYANOV DIFFERENCE ANDMINKOWSKI DIFFERENCE OF CONVEX COMPACTSUBSETS IN R2
CHUN-LING SONG,ZUN-QUAN XIA,LI-WEI ZHANG,SHU-YANG LI 한국전산응용수학회 2007 Journal of applied mathematics & informatics Vol.23 No.1
A necessary and sufficient condition for Demyanov difference and Minkowski difference of compact convex subsets in R2 being equal is given in this paper. Several examples are computed by Matlab to test our result. The necessary and sufficient condition makes us to compute Clarke subdifferential by quasidifferential for a special of Lipschitz functions.
Chun Li,Zhi-Jun Wuxiao,Xiaoqin Chen,Guanjun Chen,Yue Lu,Zhongjun Xia,Yang Liang,Hua Wang 대한암학회 2020 Cancer Research and Treatment Vol.52 No.2
Purpose Lymphoblastic lymphoma (LBL) is an invasive neoplasm of precursor T-cell or B-cell lineage. A broadly accepted standard treatment for adult LBL has not yet been defined. Materials and Methods To address this issue, we compared two chemotherapy regimens: a modified non-Hodgkin lymphoma Berlin–Frankfurt–Mu!nster-95 (NHL-BFM-95) regimen and HyperCVAD/MA. This retrospective study consecutively enrolled 207 adult LBL patients at two hospitals from 2000 to 2018. Univariate and multivariate analysis were used to assess prognostic factors. Results In the present study, most clinical characteristics were similar between the two treatment groups except for age and lactate dehydrogenase (LDH) level. Patients treated with modified NHL-BFM-95 regimen tended to be younger and with elevated LDH level. The modified NHLBFM- 95 regimen produced better treatment outcomes than those with HyperCVAD/MA in patients with T-LBL or patients < 40 years. Treatment with HyperCVAD/MA, high Eastern Cooperative Oncology Group scores, and bone marrow involvement were independent risk factors in T-LBL. No patients interrupted treatment for severe adverse events. Conclusion The results suggested that the modified regimen is well-tolerated and can produce the promising outcomes in patients with T-LBL or patients < 40 years.
Yang, Zhijie,Wang, Chun,Zhang, Xia,Li, Jing,Zhang, Ziqi,Tan, Zhao,Wang, Junyi,Zhang, Junyang,Bai, Xiaofeng The Korean Pain Society 2022 The Korean Journal of Pain Vol.35 No.4
Background: The treatment of trigeminal neuralgia remains a challenging issue. Stem cells from human exfoliated deciduous teeth (SHED) provide optimized therapy for chronic pain. This study aimed to investigate the mechanisms underlying the attenuation of trigeminal neuralgia by SHED. Methods: Trigeminal neuralgia was induced by chronic constriction injury of the infraorbital nerve. The mechanical threshold was assessed after model establishment and local SHED transplantation. Endoplasmic reticulum (ER) morphology and Caspase12 expression in trigeminal ganglion (TG) was evaluated as well. BiP expression was observed in PC12 cells induced by tunicamycin. Results: The local transplantation of SHED could relieve trigeminal neuralgia in rats. Further, transmission electron microscopy revealed swelling of the ER in rats with trigeminal neuralgia. Moreover, SHED inhibited the tunicamycin-induced up-regulated expression of BiP mRNA and protein in vitro. Additionally, SHED decreased the up-regulated expression of Caspase12 mRNA and protein in the TG of rats caused by trigeminal neuralgia after chronic constriction injury of the infraorbital nerve mode. Conclusions: This findings demonstrated that SHED could alleviate pain by relieving ER stress which provide potential basic evidence for clinical pain treatment.
Bin Yang,Peng Zhang,Shu-Chun Zhao,Ru Xia,Li-Fen Su,Ji-Bin Miao,Peng Chen,Jia-Sheng Qian,You Shi 한국고분자학회 2019 폴리머 Vol.43 No.5
The poly(lactic acid) (PLA)/graphene (GN) composites were prepared by solution blending. An in situ measurement technique was adopted to examine the non-isothermal crystallization of PLA/GN composites, which was different from the typical circumstances at constant cooling rate in DSC. The rheological properties of the samples were investigated, and the Carreau-A model was applied to non-linearly fit the rheological data. The non-isothermal crystallization kinetics and solidification behaviors at variant cooling rates were investigated using a modified version of Avrami equation by Jeziorny coupled with three-parameter model (TPM) and four-parameter model (FPM). Our findings showed that the viscosity of the PLA/GN composites dropped with increasing shear rate or GN content. Crystallization kinetic analysis suggested that GN served as an effective nucleating agent for PLA under non-isothermal melt crystallization conditions with variant cooling rate.
Genome-wide identification and evolutionary analysis of WOX gene family in cucurbit crops
Li Chun,He Zhen,Liang Genyun,Yang Nan,Cai Peng,Liang Ying,Li Yuejian,Fang Chao,Liu Duchen,Xia Feng,Liu Xiaojun 한국원예학회 2024 Horticulture, Environment, and Biotechnology Vol.65 No.1
The WUSCHEL-related homeobox (WOX) gene family is essential for plant growth and development. However, the identifi cation and evolutionary analysis of WOX genes in the Cucurbitaceae have not been well investigated. In the present work, we performed a genome-wide analysis to identify WOX genes in eleven cucurbit crops. In total, 127 WOX genes were identifi ed in eleven cucurbit crops, and classifi ed into three diff erent clades: the ancient clade, the intermediate clade and the WUS clade. The same clade has comparable gene organization and conserved motif patterns. The cis -acting ele ment analysis revealed that WOX genes were involved in light, hormone and stress in cucurbit crops. Gene duplication analysis indicated that dispersed duplication and whole genome duplication were the two primary causes of WOX genes expansion. There were 24 and 129 gene pairs found within cucurbit crops, and between Cucumis sativus and other cucur bit crops, respectively. After gene duplication, all WOX genes were subjected to substantial purifying selection pressure according to the selective pressure analysis. Functional divergence analysis revealed that ancient and intermediate clades may have descended from some essential amino acid sites rather than diff erent evolution rate. Our research provides a comprehensive analysis of WOX genes which will be helpful for further research into their function study in Cucurbita ceae plants.
Fu, Chun-Jing,Pan, Xiong-Fei,Zhao, Zhi-Mei,Saheb-Kashaf, Michael,Chen, Feng,Wen, Ying,Yang, Chun-Xia,Zhong, Xiao-Ni Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.15
Objectives: To evaluate medical students' knowledge of HPV and HPV related diseases and assess their attitudes towards HPV vaccination. Methods: A total of 605 medical undergraduates from Chongqing Medical University in China were surveyed using a structured and pretested questionnaire on HPV related knowledge. Results: Some 68.9% of the medical students were females, and mean age was 21.6 (${\pm}1.00$) years. Only 10.6% correctly answered more than 11 out of 14 questions on HPV related knowledge, 71.8% being willing to receive/advise on HPV vaccination. Female students (OR: 2.69; 95% CI: 1.53-4.72) and students desiring more HPV education (OR: 4.24; 95% CI: 1.67-10.8) were more willing to accept HPV vaccination. HPV vaccination acceptability was observed to show a positive association with HPV related knowledge. Conclusions: Our survey found low levels of HPV related knowledge and HPV vaccination acceptability among participating medical students. HPV education should be systematically incorporated into medical education to increase awareness of HPV vaccination.
Bin Yang,Lei Hu,Ru Xia,Fang Chen,Shu-Chun Zhao,Yan-Li Deng,Ming Cao,Jiasheng Qian,Peng Chen 한국고분자학회 2016 Macromolecular Research Vol.24 No.1
In this study, nanofillers composed of hydroxylated carbon nanotubes (h-CNT), carbon nanotubes (CNT) and graphene (GR) were separately added into the dynamically-vulcanized polypropylene (PP)/ethylene-propylenediene monomer (EPDM) blend. Differential scanning calorimetry (DSC), wide-angle X-ray diffraction (WAXD) and electrical resistivity measurements were employed to study the effect of nanofillers on the melt behavior, non-isothermal crystallization behavior and electrical conductivity of the prepared composites. WAXD results showed that h-CNT had a better induction effect of β-PP in the nanocomposites. The sequence of the activity in inducing the formation of β-PP was h-CNT>GR>CNT. However, the total crystallinity of the nanocomposites nearly remained constant. Non-isothermal crystallization kinetic analysis indicated that the presence of nanofillers improved the crystallization rate of the nanocomposites. The consequence of nucleation activity was as follows: CNT>GR>h-CNT. Although EPDM hindered the macromolecular motion of PP, interestingly it could increase the crystallization rate to an extent. Besides, the influence of nanofillers on enhancing the conductive property of the nanocomposites can be ranked as follow: CNT>GR>h-CNT.
Xue Yang,Jian Chen,An Pan,Jason H.Y. Wu,Fei Zhao,Yue Xie,Yi Wang,Yi Ye,Xiong-Fei Pan,Chun-Xia Yang 대한당뇨병학회 2020 Diabetes and Metabolism Journal Vol.44 No.3
Background: To examine the prospective association between higher blood pressure (BP) and risk of type 2 diabetes mellitus (T2DM) in middle-aged and elderly Chinese adults. Methods: A total of 9,642 middle-aged and elderly Chinese adults (≥45 years old; 47.30% men) without diabetes from the China Health and Retirement Longitudinal Study were included for analyses. Participants were categorized into three groups: normal BP, prehypertension, and hypertension, according to the 2010 Chinese Guidelines for the Management of Hypertension. The incidence of T2DM was determined by self-reported physician diagnosis during two follow-up surveys conducted in 2013 to 2014 and 2015 to 2016. Results: During the 4-year follow-up, 429 participants (4.45%) developed T2DM, including 3.51% of the men and 5.29% of the women. The incidence rates of T2DM were 2.57%, 3.75%, and 6.71% in the normal BP, prehypertension, and hypertension groups, respectively. After adjustment for age, sex, education level, residence, smoking status, alcohol consumption, body mass index, waist circumference, and dyslipidemia, both prehypertension (odds ratio [OR], 1.32; 95% confidence interval [CI], 0.98 to 1.77) and hypertension (OR, 2.02; 95% CI, 1.54 to 2.64) were associated with increased risk of T2DM, compared to those with a normal BP. The ORs associated with T2DM were 1.08 (95% CI, 1.03 to 1.13) for an increase of 10 mm Hg in systolic BP and 1.06 (95% CI, 1.01 to 1.10) for an increase of 5 mm Hg in diastolic BP. Conclusion: Higher BP is a risk factor for T2DM in middle-aged and elderly Chines. It may be a potential target for diabetes prevention.