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      • KCI등재

        가속도계를 이용한 재료의 영계수 측정방법

        손창호(Sohn, Chang-Ho),박진호(Park, Jin-Ho),윤두병(Yoon, Doo-Byung),정의필(Chong, Ui-Pil),최영철(Choi, Young-Chul) 한국소음진동공학회 2006 한국소음진동공학회 논문집 Vol.16 No.11

        For the description of the elastic properties of linear objects a convenient parameter is the ratio of the stress to the strain, a parameter called the Young's modulus of the material. Young's modulus can be used to predict the elongation or compression of an object as long as the stress is less than the yield strength of the material. Conventional method for estimating Young's modulus measured the ratio of stress to corresponding strain below the proportional limit of a material using a tensile testing machine. But the method needs precision specimens and expensive equipment. In this paper, we proposed method for estimating Young's modulus using accelerometer. The basic idea comes from that the wave velocity is different as the Young's modulus. To obtain Young's modulus, a group velocity is obtained. It is difficult to measure group velocity. This is because plate medium has a dispersive characteristics which has different wave speed as frequency. In this paper, we used Wigner-Ville distribution to measure group velocity. To verify the proposed method, steel and acryl plate experiments have been performed. Experimental results show that the proposed method is powerful for estimating Young's modulus.

      • SCIESCOPUSKCI등재
      • 人蔘의 Oil중의 β-sitosterol의 確認 및 定量

        安永弼,鄭鍾天 건국대학교 1970 學術誌 Vol.11 No.1

        β-sitosterol was separated in korean panax ginseng by TLC and was identified by N.M.R. mass spectra, IR, and T.L.C. method Form our result, free campesterol and stigmasterol absent while contained only free β-sitosterol in ether extract fraction. The quantitative determination of the β-sitosterol was performed with colorimetry method. Average amount were 2.0mg-3.5mg per ten gram of ginseng powder.

      • Comparative double blind test에 의한 抗아메바劑 Ro7-0207(Tiberal), Metronidazole 및 Dehydroemetine의 治效成績의 比較

        李午政,全鍾暉,朴弼遠,朴壽泳 대한감염학회 1974 감염 Vol.6 No.1

        Introduction New and better substances are still being sought for the treatment of amoebiasis. The aim of this trial is to assess the effectiveness and tolerance of Tiberal and oral dehydroemetine in patients with oligosymptomatic (or mild) intestinal amoebiasis comparing with that of metronidazole which are known to be an active amoebicide. Selection of cases. Lately, classical symptomatic amoebiasis accompanying mucus-bloody stool and tenesmus could be seldom experienced at urban areas in this country. At here the majority of intestinal amebiasis is manifested by loose stools containing mucus, pus or blood (rare), and also by a rapid response to antibioties, but with frequent episods of recurrence caused by diet-failure or alcohol drinking. Among 187 cases of mild enterocolitis which were suspected as being mild intestinal amoebiasis clinically, authors selected amoeba-positive 60 cases and additional 7 cases which were included later in this clinical trial study. The 7 drop-outs in the original study were replaced by these additional 7 cases. The clinical trials were carried out at the St. Mary's Hospital, Catholic Medical College, Seoul, Republic of Korea. During 12 month (April 25, 1973-May 17, 1974), we treated 60 cases of so-called oligosymptomatic amoebiasis with above mentioned three amoebicides. 60 ambulatory cases suffering from mild GI troubles were admitted into the trial (liable to recurrent diarrhoeal stools including mucus, or pus with tenesmus, and also to lower abdominal discomfort of mild pain) those were suspected clinically as having intestinal amoebiasis with carriers of E. histolytica (trophozoits and/or cysts in the feces). Oligosymptomatic amoebiasis group, in this clinical trial study, consisted of 34 males and 26 females ranging from 17 to 62 years of age. All were adolescents or adults and their age distribution was shown in Table 1. Methodology on this clinical trials. We have carried out so-called the comparative double blind trials with Tiberal versus Metronidazole versus oral Dehydroemetine in symptomatic amoebiasis of mild grade. The trial drugs were given also without the knowledge of either the one who gave it or the one who got it in this comparative double blind study. Both (drug examiner) doctors and (drug examined) patients have had no knowledge of each drug. Pharmacist responded to doctor's prescription with code numbers. After the completion of the study the exact name of a drug were publically drawn from the code numbers and the purpose of double blind study was attained. In this study an arrangement for a drug administration schedule was set by as pharmacist exclusively. 60 patients were assigned to one of the three drugs by proper randomization so that 20 patients received tiberal and 20 metronidazole and 20 oral dehydroemetine. After the trial, code numbers of the drugs were identified; nos. 1, 6, 10, 14, 19, 23, 25, 27, 28, 29, 33, 34, 35, 36, 44, 45, 47, 51, 53, and 54 were tiberal; 8, 9, 11, 12, 13, 15, 16, 18, 20, 22, 32, 39, 41, 48, 49, 50, 52, 55, 56, and 57 were metronidazole, and nos. 2, 3, 4, 5, 7, 17, 21, 24, 26, 30, 31, 37, 38, 40, 42, 43, 46, 58, 59 and 60 were oral dehydroemetine. Evaluation The therapeutic effects were assessed by the clinical evolution and by stool parasitology (direct examination and concentration method) performed on day 3 and 6 on treatment, and then at the end of treatment (8-10 day) and one month after the initial treatment. This made a total 4 to 5 parasitological examination per patient, including one examination required for diagnosis prior to treatment. At the same time aspect and consistency of the stool were registered. The effect of the drugs on other protozoa found in the stools were also reported. The tolerance were assessed by clinical findings and laboratory studies made in limited cases at least before and after treatment unless otherwise stated. Blood count, BUN, Alkaline phosphatase, SGP, TECG and urinalysis were performed as laboratory controls. Authors have established following evaluation criteria for this clinical study. Radical cure: free of symptoms with no vegetative or cystic forms of E. histolytica in stool on 3 successive tests. Biological cure: no cystic forms of E. histolytica in stool on 3 successive tests, but persistence of some intestinal disturbances. Relapse: apparent cure or improvement (with negative of 3 successive tests) followed by recurrence with vegetative amoeba on direct smear within 30 days. (re-infection may be included) Failure: the trophozoites or cystic form of E. histolytica has persisted for treatment periods, with some intestinal troubles. Methods of treatment and parasitologic examination In each group one third of the patients received 2 capsnles of 250mg. Tiberal thrice daily for 7 days, one third received 2 tablets of 250 mgmetronidazole thrice daily for 7 days, and one third received 2 tablets of 10 mgdehydroemetine thrice daily for 7 days as the only specific drug. No associated drugs were given together for symptomatic relief in all cases. The reason why fixed 7 days dose were delivered to every cases was based on convenience of stool examination and equalizing the number of days for therapy. The therapeutic drugs were delivered usually for 2 days dose (1st prescription), 3 days dose and 2 days dose (3rd prescription) successively, therefore stool examination had been done on 3rd, 6th and 8-10th day of therapy. Clinical results In oligosymptomatic amoebiasis, 20 cases each were treated with doses of 1,500mg/day of Tiberal and metronidozole for 7 days respectively, and 20 cases were treated with doses of 60mg/day of dehydroemetine for 7 days. The total doses administered were 10,5g, 10,5g, and 420mg respectively in a period of 7 days. Among tiberal group 19 cases were found to be negative after therapy whereas there was 1 with parasitological failure. The clinical effect was fast in 95% of the cases. Effective cure was achieved in 17 whereas symptoms persist in 3 patients among 20 cases. There were 1 failure and 2 late relapse. Comparing data of therapeutic results with that of metronidazole and dehydroemetine were shown in Table 2 & 3. Table 3 shows the negativity rate of trophozoits or cystic form of E. histolytica in stools according to therapeutic periods of trial drugs received. The data would indicated that 5 days dose could not be enough to eradicate the parasites even in the susceptible cases. The result data of clinical improvement and clearance of E. histolytica in patient stool among drug trial groups were shown in Table 4. The cases treated with Tiberal showed no clinical signs on average 4,9 days and negative amoeba in stool on average 4,1 days of therapeutic periods, comparing with on average 5,8 days and 4,1 days in metronidazole-treated group, and on average 6,3 days and average 4,5 days in dehydroemetine-treated group respectively. Authors put in order the therapeutic procedures and their result of failed or relapsed cases with unplanned measures in table 5. These data could be obtained after the completion of the comparative double blind study by the code numbers which were publically drawn afterwards. These therapeutic procedures had been made just incidentally, not by prior plan. 2 cases, 4 cases and 3 cases could get finally effective cure by doubling doses of 7 days course of Tiberal, metronidazole and dehydroemetine respectively. 1 failed case treated with dehydroemetine and 1 another failed case with tiberal could get effective cure by additionally receiving metronidazole and dehydroemetine respectively. 2 failed cases treated with metronidazole could be cleared of parasites by adding tiberal effectively. Adverse reactions were noticed in 20% each of the patients treated with Tiberal and also with metronidazole, and 25% of those treated with dehydroemetine. They were all transient and never severe. There was not a single case who was discontinued on therapy owing to its side-effects. No significant change of laboratory data was noticed by the administration of trial drugs. Brief summary Tiberal, metronidazole and dehydroemetine (oral) were all recognized as highly efficacious anti-amoebic drugs in this clinical studies. On account of following standpoints 1) clearance of parasites in stool 2) clinical symptomatic relieving 3) drug tolerance 4) rate of relapse and failure 5) side-effects, Tiberal could be received much more recognition than metronidazole and dehydroemetine did. P. S. Authors has experienced other 10 cases of amoebiasis among in patients (5 moderate severe intestinal amoebiasis, 4 liver abscesses and 1 lung abscess) treated with Tiberal and metronidazole with excellent therapeutic results, without any sequelae or relapse.

      • Quinupristin-dalfopristin versus linezolid for the treatment of vancomycin-resistant Enterococcus faecium bacteraemia: efficacy and development of resistance.

        Chong, Yong Pil,Lee, Sang-Oh,Song, Eun Hee,Lee, Eun Jung,Jang, Eun-Young,Kim, Sung-Han,Choi, Sang-Ho,Kim, Mi-Na,Jeong, Jin-Yong,Woo, Jun Hee,Kim, Yang Soo Scandinavian University Press [etc.] 2010 Scandinavian journal of infectious diseases Vol.42 No.6

        <P>Quinupristin-dalfopristin and linezolid are widely used for the treatment of vancomycin-resistant Enterococcus faecium (VREF) infections. Increasing resistance of VREF to quinupristin-dalfopristin and linezolid is a cause for concern. To determine the efficacy of and the rate of development of resistance to quinupristin-dalfopristin and linezolid, we analyzed all episodes of clinically significant VREF bacteraemia at a tertiary-care hospital from January 2003 to June 2007. The main outcomes were rates of 30-day mortality, microbiological response, and development of resistance. Fifty-two patients were treated with quinupristin-dalfopristin and 61 were treated with linezolid. Baseline demographic and clinical characteristics were similar between the 2 groups. There were no significant between-group differences in 30-day mortality (48% in the quinupristin-dalfopristin group vs 41% in the linezolid group; p = 0.45) or microbiological response (60% vs 66%; p = 0.51). However, prolonged bacteraemia (18% of 45 evaluable cases vs 4% of 55 evaluable cases; p = 0.04) and development of resistance in blood isolates (11% vs 0%; p = 0.02) were more frequently observed in the quinupristin-dalfopristin group than in the linezolid group. There was no significant difference between the efficacy of quinupristin-dalfopristin and linezolid. However, prolonged bacteraemia and the development of resistance were more common in quinupristin-dalfopristin-treated patients.</P>

      • KCI등재

        LANDSAT DATA의 영상처리수법(映像處理手法)에 의한 서울-동두천(東豆川) 간(間)의 LINEAMENT 연구(硏究)

        강필종 ( Pil Chong Kang ),지광훈 ( Kwang Hoon Chi ),조민조 ( Min Joe Cho ),최영섭 ( Young Sup Choi ) 大韓遠隔探査學會 1985 大韓遠隔探査學會誌 Vol.1 No.1

        The study was emphasized on application of the digital image processing techniques for lineament analysis. The major lineament of the study area belongs to Choogaryong faults which many geologists have studied since 1903. Also the lineament is so significant in geological views, because the lineament runs through Seoul area. The several image processing methods such as gradient, Laplacian and spatial filter have been applied, and the spatial filtering is most suitable method for lineament analysis among them. The lineaments distribute predominently in the N20°-30°E trend and N80°-90°W trend which have the conjugated relationship each other, and it coincides with the Gyeongsang conjugate system. The circular structure of study area was developed by cooling circular joint.

      • KCI등재

        LANDSAT TM자료(資料)에 의한 광화대조사(鑛化帶調査) 응용기법개발(應用技法開發)

        강필종 ( Pil Chong Kang ),지광훈 ( Kwang Hoon Chi ),조민조 ( Min Joe Cho ),최영섭 ( Young Sup Choi ) 大韓遠隔探査學會 1986 大韓遠隔探査學會誌 Vol.2 No.2

        TM data, which have better resolution in spatial and spectral than MSS data, were used for this study, and several Image Processing Techniques(IPT) were examined for finding the best IPT to fit to lineament extraction and mineralized zone mapping. The Ryeongnam area was selected as a test area, because the area is one of major mineralized zones in Korea and its hydrothermal alteration zone is wider and deeper than other areas. The spatial filtering method is most optimum one for lineament extraction: that is, the directional spatial filtering is most efficient to detect N-S, E-W direction lineaments on the image, and the high boost filtering can be applied for mapping all direction lineaments. The ratio method was selected for detecting altered zone. It is possible to make several tens combinations in ratio with 7 bands of TM data, but considering spectral characteristics of each band of TM to the geological meterials and vegetation, the band 4/band 3(A), band 5/band 7(B), and B/A ratio methods were chosen among them. The 5/7 ratio image did not show clearly the altered area due to noise from vegetation cover, so the 4/3 ratio image was used for trying to decrease the effect of vegetation. As a result the B/A ratio image showed quite nicely the altered zone of the test area. In conclusion, the spatial filtering is the best image processing techniques for lineament mapping, and the B/A ratio image in TM data is useful for the mineralized zone mapping.

      • SCIESCOPUSKCI등재

        Nutritional characteristics of horsemeat in comparison with those of beef and pork

        Lee, Chong-Eon,Seong, Pil-Nam,Oh, Woon-Young,Ko, Moon-Suck,Kim, Kyu-Il,Jeong, Jae-Hong The Korean Nutrition Society 2007 Nutrition Research and Practice Vol.1 No.1

        This study was conducted to determine the nutritional characteristics of horsemeat and bone meal in comparison with those of beef and pork presented by Dietary Reference Intakes For Koreans. Longissimus muscle and large metacarpal bone samples were collected from 20 fattened Jeju horses. Muscle samples were subjected to proximate analysis, assays for fatty acid profile and minerals, and bone samples to mineral assays. Horsemeal had similar levels of protein (21.1 vs 21.0 or 21.1%) and lower levels of fat (6.0 vs 14.1 or 16.1%) compared with beef or pork, respectively. Horsemeat had much higher levels of palmitoleic (8.2 vs 4.4 or 3.3%) and $\alpha-linolenic$ (1.4 vs 0.1 or 0.6%) acids than beef or pork, respectively. Linoleic acid was much higher in horsemeat (11.1%) and pork (10.1%) than in beef (1.6%). PUFA:SFA and n-6:n-3 ratios in horsemeat were 0.29 and 10.2, respectively. There were no big differences in mineral contents between horsemeat, beef and pork. For daily recommended mineral intakes of male adults (Dietary Reference Intakes For Koreans), phosphorus, sodium, potassium, iron, zinc and copper can be provided up to 24, 2.5, 6.7, 21, 26 and 40%, respectively, by 100 g raw horsemeat, but calcium and manganese levels are negligible. Horse cannon bone had much higher mineral contents especially in calcium (10,193 mg/100 g), phosphorus (5,874 mg/100 g) and copper (0.79 mg/100 g). Thiamin, riboflavin, niacin and retinol contents were 0.20, 0.21, 1.65 mg/100 g and $30{\mu}g/100g$, respectively. But ascorbic acid and beta-carotene were not detected. Our data demonstrated that higher levels of palmitoleic and $\alpha-linolenic$ acid in horsemeat than in beef and pork may be beneficial for human health. Horsemeat and bone meal are a good source of some minerals and vitamins.

      • KCI등재후보

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