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최문영 ( Choe Mun Yeong ),송현주 ( Song Hyeon Ju ),김미연 ( Kim Mi Yeon ),이영숙 ( Lee Yeong Sug ),김승정 ( Kim Seung Jeong ),최규복 ( Choe Gyu Bog ),윤견일 ( Yun Gyeon Il ),강덕희 ( Kang Deog Hui ),박기덕 ( Park Gi Deog ) 대한신장학회 2004 Kidney Research and Clinical Practice Vol.23 No.2
Baclofen, a derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), is used for the treatment of muscle spasm, intractable hiccups and multiple sclerosis. It is mostly excreted by glomerular filtration with a clearance that is proportional to creatinine clearance. Early hemodialysis is a treatment of the choice for baclofen-induced neurologic complication in renal failure patients. We experienced a 57-year-old hemodialysis patient with right arm muscle spasm who developed baclofen-associated encephalopathy by a single dose of oral baclofen (10 mg). He admitted to the hospital with the symptom of stuporous mental status with no specific focal neurologic signs. Brain CT imaging and blood biochemistry showed no specific abnormality. EEG revealed the typical metabolic encephalopathy findings, such as triphasic wave and frontal lobe syndrome with delta wave. After daily hemodialysis for 3 days, there was a complete recovery of an altered mentality. After one month later, the follow-up EEG showed normal finding with the resolution of abnormal waves. We report this case with a review of relevant literature. Baclofen should be used carefully, and rather recommended not to be administered in patients with renal failure. (Korean J Nephrol 2004;23(2):353-357)
현동우 ( Hyeon Dong U ),박수영 ( Park Su Yeong ),조창민 ( Jo Chang Min ),탁원영 ( Tag Won Yeong ),권영오 ( Kwon Yeong O ),김성국 ( Kim Seong Gug ),최용환 ( Choe Yong Hwan ) 대한내과학회 2003 대한내과학회지 증례 특집호 65-5 부록3 Vol.0 No.-
Hypereosinophilic syndrome is a very rare disease characterized by marked peripheral eosinophilia and eosinophilic infiltration of organs such as the heart, nervous system, skin, liver, spleen, gastrointestinal tracts, lung and urinary system. Clinical ma
최윤영 ( Choe Yun Yeong ),현길수 ( Hyeon Gil Su ),최정우 ( Choe Jeong U ) 한국수처리학회 2004 한국수처리학회지 Vol.12 No.1
N/A In this research the Koreanized 3-DFM model(ver. 1.1.1) has been designed to establish the program mentioned above, and 3-DFM(ver. 1.1.2) is reconstructed that equipped with strengthened graphic function for post processes. All the input data settings of the 3-DFM model which is developed in this study are organized in Korean, and the model contains help function for each input data. Thus, it is designed to get detailed information about each input parameter when the mouse pointer is placed on the corresponding input parameter. This model also is designed to easily specify the geologic boundary condition for each stratum or initial head data in the work sheet. In addition, this model is designed to display boxes for input parameter writing for each analysis condition so that the setting for each parameter is not so complicated as existing MODFLOW is when steady and unsteady flow analysis are performed as well as the analysis for the characteristics of each stratum. Descriptions for input data are displayed on the right side of the window while the analysis results are displayed on the left side as well as the TXT file for this results is available to see. The model developed in this study is a numerical model using finite differential method, and the applicability of the model was examined by comparing and analyzing observed and simulated groundwater heads computed by the application of real recharge amount and the estimation of parameters. The 3-DFM model is applied in this study to Sehwa-ri, and Songdang-ri area, Jeju, Korea for analysis of groundwater flow system according to pumping, and obtained the results that the observed and computed groundwater head were almost in accordance with each other showing the range of 0.03-0.07 error percent. 3-DFM(ver. 1.1.2) model in this research, strengthened the graphic (post processes) functions, needs to set precise helps of input parameters and output values for the people in charge to conveniently apply the model to the site. Therefore it is thought that there are many things to be improved through collecting various data, and that such defects should be given priority to be complemented an dimproved in the future.
현일식 ( Hyeon Il Sig ),조경란 ( Jo Gyeong Lan ),백상현 ( Baeg Sang Hyeon ),김진배 ( Kim Jin Bae ),최호순 ( Choe Ho Sun ),이오영 ( Lee O Yeong ),한동수 ( Han Dong Su ),손주현 ( Son Ju Hyeon ),함준수 ( Ham Jun Su ),이민호 ( Lee Min 대한소화기학회 2003 대한소화기학회 추계학술대회 Vol.2003 No.-
원발성 간세포암종은 간 외로 전이하는 경우가 드문 암이다. 전이가 있는 경우 주로 폐, 복부 임파선, 뼈, 뇌 순으로 전이된다. 그러나, 전이성인 경우라도, 간 종물 없이 전이 병변만 발견된 경우는 보고된 바가 없었다. 이에 간 종물 없이 흉벽에서만 발견된 전이성 간세포암종을 경험하였기에 보고하는 바이다. 51세 남자로, 좌상부 흉벽에 약 12×10㎝ 크기로 단단한 종물이 촉지되고 8개월 전부터 크기가 증가되어 내원하였다. 환자는 10년 전 만성 B형
ABCA1 expression of human gallbladder tissue in various gallbladder diseases
최호순 ( Choe Ho Sun ),노나영 ( No Na Yeong ),백상현 ( Baeg Sang Hyeon ),조경란 ( Jo Gyeong Lan ),이오영 ( Lee O Yeong ),한동수 ( Han Dong Su ),손주현 ( Son Ju Hyeon ),함준수 ( Ham Jun Su ),백승삼 ( Baeg Seung Sam ),이진 ( Lee Ji 대한소화기학회 2003 대한소화기학회 추계학술대회 Vol.2003 No.-
<목적> 담낭상피는 담즙 내의 고 농도의 콜레스테롤에 노출되어 있으므로, 수동적 혹은 능동적으로 콜레스테롤과 phospholipids를 흡수한다. 그러나 흡수된 콜레스테롤과 phospholipids의 운명에 대해서는 잘 알려져 있지 않다. Dog gallbladder epithelial cells (DGBEC)을 이용한 In vitro 연구에서 basolateral cholesterol/phospholipid efflux는 ABCA1 (ATP-bindi
류마토이드 관절염과 연관된 이차성 신유전분증에서의 반월상 사구체 신염
최정현 ( Choe Jeong Hyeon ),임병국 ( Im Byeong Gug ),최준혁 ( Choe Jun Hyeog ),조현경 ( Jo Hyeon Gyeong ),최영일 ( Choe Yeong Il ),김흥수 ( Kim Heung Su ),신규태 ( Sin Gyu Tae ),김도헌 ( Kim Do Heon ),한재호 ( Han Jae Ho ) 대한신장학회 2001 Kidney Research and Clinical Practice Vol.20 No.6
A case of renal amyloidosis with crescentic glomerulonephritis associated with rheumatoid arthritis is described. A 60-year-old female with 15 years` history of rheumatoid arthritis developed nephrotic syndrome followed by rapid deterioration of renal function. Glomerular amyloid deposition and sclerotic change was present in kidney biopsy specimen and crescentic change was found in 85% of the glomerulus. Electron microscopic finding of glomerulus showed randomly oriented, rigid-appearing, long nonbranching fibrils. The patient was treated with intravenous high-dose methylprednisolone pulses combined with intravenous cyclophosphamide followed by oral corticosteroids. Three months after the above treatment, renal function gradually improved, reaching serum creatinine level to 2.5 mg/dL. But the nephrotic range proteinuria persisted.
일반연제 발표 : 비당뇨병성 만성 신질환 환자에서 안지오텐신 수용체 길항제의 단백뇨 감소 효과에 대한 안지오텐신 전환 효소 유전자 다형성의 영향
최훈영 ( Choe Hun Yeong ),김현진 ( Kim Hyeon Jin ),김형종 ( Kim Hyeong Jong ),김현욱 ( Kim Hyeon Ug ),장제현 ( Jang Je Hyeon ),김범석 ( Kim Beom Seog ),강신욱 ( Kang Sin Ug ),최규헌 ( Choe Gyu Heon ),이호영 ( Lee Ho Yeong ),한대석 대한신장학회 2003 춘계학술대회 초록집 Vol.22 No.1