Anesthetic Management and Outcomes of Endovascular Treatment of Basilar Artery Occlusion: Results From the ATTENTION Registry

Tao Chunrong,Yuan Guangxiong,Xu Pengfei,Wang Hao,Zhou Peiyang,Yi Tingyu,Li Kai,Cui Tao,Gao Jun,Li Rui,Sun Jun,Zhang Chao,Wang Li,Liu Tianlong,Song Jianlong,Yin Yamei,Nguyen Thanh N.,Li Qing,Hu Wei 대한뇌졸중학회 2023 Journal of stroke Vol.25 No.3

Background and Purpose To examine the clinical and safety outcomes after endovascular treatment (EVT) for acute basilar artery occlusion (BAO) with different anesthetic modalities. Methods This was a retrospective analysis using data from the Endovascular Treatment for Acute Basilar Artery Occlusion (ATTENTION) registry. Patients were divided into two groups defined by anesthetic modality performed during EVT: general anesthesia (GA) or non-general anesthesia (non-GA). The association between anesthetic management and clinical outcomes was evaluated in a propensity score matched (PSM) cohort and an inverse probability of treatment weighting (IPTW) cohort to adjust for imbalances between the two groups. Results Our analytic sample included 1,672 patients from 48 centers. The anesthetic modality was GA in 769 (46.0%) and non-GA in 903 (54.0%) patients. In our primary analysis with the PSM-based cohort, non-GA was comparable to GA concerning the primary outcome (adjusted common odds ratio [acOR], 1.01; 95% confidence interval [CI], 0.82 to 1.25; <i>P</i>=0.91). Mortality at 90 days was 38.4% in the GA group and 35.8% in the non-GA group (adjusted risk ratio, 0.95; 95% CI, 0.83 to 1.08; <i>P</i>=0.44). In our secondary analysis with the IPTW-based cohort, the anesthetic modality was significantly associated with the distribution of modified Rankin Scale at 90 days (acOR: 1.45 [95% CI: 1.20 to 1.75]). Conclusion In this nationally-representative observational study, acute ischemic stroke patients due to BAO undergoing EVT without GA had similar clinical and safety outcomes compared with patients treated with GA. These findings provide the basis for large-scale randomized controlled trials to test whether anesthetic management provides meaningful clinical effects for patients undergoing EVT.

Chaotic dynamic characteristics of pressure fluctuation signals in hydro-turbine

Wen-Tao Su,Xiao-Bin Li,Chao-Feng Lan,Shi An,Jiansheng Wang,Feng-Chen Li 대한기계학회 2016 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.30 No.11

The pressure fluctuation characteristics in a Francis hydro-turbine running at partial flow conditions were studied based on the chaotic dynamic methods. Firstly, the experimental data of pressure fluctuations in the draft tube at various flow conditions was de-noised using lifting wavelet transformation, then, for the de-noised signals, their spectrum distribution on the frequency domain, the energy variation and the energy partition accounting for the total energy was calculated. Hereby, for the flow conditions ranging from no cavitation to severe cavitation, the chaos dynamic features of fluctuation signals were analyzed, including the temporal-frequency distribution, phase trajectory, Lyapunov exponent and Poincaré map etc. It is revealed that, the main energy of pressure fluctuations in the draft tube locates at low-frequency region. As the cavitation grows, the amplitude of power spectrum at frequency domain becomes larger. For all the flow conditions, all the maximal Lyapunov exponents are larger than zero, and they increase with the cavitation level. Therefore, it is believed that there indeed exist the chaotic attractors in the pressure fluctuation signals for a hydro-turbine.

Study on flexible two-axis roll-bending process for component with non-circular section

Tao Zhang,Huapu Sha,Shihong Lu,Chao Du,Peng Chen 대한기계학회 2019 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.33 No.9

Two-axis roll-bending technology, with the advantages of small curvature radius, short straight section and high efficiency, is widely used in fields of aerospace and automobile. By adjusting indentation depth in two-axis roll-bending process, different curvature radius of circular and elliptic component can be formed. Roll-bending experiments and numerical simulations for component with circular and elliptic section are conducted. The results show that the forming curvature radius of circular component and its deviation both decrease with ascending indentation depth. The relationship between forming curvature radius and indentation depth is polynomial fitted. On this basis, ellipse parameter equation is established and different curvature radius at different position of the ellipse is achieved by adjustment of indentation depth. The relationship between indentation depth and forming time is obtained for elliptic component. Elliptic components with different sizes are formed. The stress distribution is uniform after roll-bending process and it increases with ascending indentation depth.

Deformation Characteristics of Soft Soil Induced by Deep Excavation and Its Impact on Adjacent Tunnels: A Case Study in Shanghai

Tao Peng,Dongxing Ren,Chao Kang,Huanhuan Liu,Peng Xue,Hai Huang 대한토목학회 2024 KSCE Journal of Civil Engineering Vol.28 No.5

This research aims to comprehensively study the deformation characteristics of an excavation pit of 7,600 m2 (117 m long, 65 m wide and 20.8 m deep) in soft clay in Shanghai, China. The deformation characteristics of the mixing pile in both the vertical and lateral directions, ground surface movement, and surface displacement in the adjacent tunnels were comprehensively investigated. The results indicated that the maximum lateral deflection was approximately 85 mmat the end of the excavation and that the maximum lateral displacement, hm, was in the range between 0.12%He and 0.41%He. The factor of safety of the excavation was approximately 1.6, which was larger than that of most reported sites in Shanghai. The relationship between heaving and excavation depth was strong between 0.0047%He and 0.056%He, and a relatively large settlement was observed at a distance of approximately 0.2He – 0.3He. The tunnel surface of the eastbound line deformed upward and inward with a maximum horizontal convergence of 4 mm. A multilayer regression model was also validated, showing a maximum discrepancy of 26.5 mm. This research provides a valuable historical case for the documentation of the deformation characteristics of excavation pits close to existing foundation pits and tunnels.

Analysis of Local Surface Plasmon Resonance in Multilayered Au/Ag/Graphene Nanoshells

Chao Liu,Zhaoting Liu,Jingwei Lv,Tao Sun,Qiang Liu,Haiwei Mu,Paul K. Chu 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2017 NANO Vol.12 No.5

"The localized surface plasmon resonance (LSPR) properties of Au/Ag/graphene nanoshells are studied by discrete dipole approximation (DDA). The coupled resonance wavelengths show a remarkable dependence on the graphene thickness as well as refractive index of the surrounding medium. The resonance wavelengths of Au/Ag/graphene nanoshells red-shift as the thickness of the graphene layer is increased, when the radii of the Au core and Ag interlayer are 40 nm and 45nm, respectively. Specifically, the longer wavelength red-shifts from 540 nm to 740 nm when the refractive index varies from 1.25 to 2.05. "

3D Analysis on Surrounding Soil Stability of Shaft Boring Machine Based on Plastic Limit Equilibrium Theory

Chao Li,Tao Li,Zhongqi Shi,Jinhui Li,Guoye Jing 대한토목학회 2021 KSCE JOURNAL OF CIVIL ENGINEERING Vol.25 No.11

Shaft boring machine (SBM) plays a significant role in mechanized construction of deep and large shafts. However, surrounding soil instability of SBM pose great threats to the shaft construction. Therefore, it is necessary to analyse the soil stability underlying SBM’s gripper. On the basis of the first SBM (MSJ5.8/1.6D) that independently developed in China, the interaction between the SBM’s gripper and surrounding soil is investigated. According to the failure mode of the shaft obtained by numerical simulation, the geometry of the failure surfaces is first derived, and the stresses distribution on the failure surfaces are clearly presented. Then, the ultimate bearing capacity formula of the surrounding soil underlying SBM’s gripper is derived based on plastic limit equilibrium theory with Mohr-Coulomb criterion. The change rules of bearing capacity factors and the influence rules of basic parameters in this formula are obtained. Finally, the theoretical values in typical soils are compared with those from the numerical simulation to illustrate the rationality of the formula. The results of this investigation not only provide an advanced method for evaluating the surrounding soil stability of SBM in shaft construction, but also provide guidelines for the design and construction risk control of SBM.

H2O2 regulates root system architecture by modulating the polar transport and redistribution of auxin

Chao Su,Liu Liu,Haipei Liu,Brett J. Ferguson,Yanmin Zou,Yankun Zhao,Tao Wang,Youning Wang,Xia Li 한국식물학회 2016 Journal of Plant Biology Vol.59 No.3

The accumulation and redistribution of the plant hormone auxin plays a crucial role in root development and patterning. Plants can alter their root system architecture (RSA) to adapt to different biotic and abiotic stresses. In addition, reactive oxygen species (ROS), such as H2O2, are known to increase in plants undergoing stress. Here, we present evidence that H2O2 can regulate auxin accumulation and redistribution through modulating polar auxin transport, leading to changes in RSA. Plants exposed to different concentrations of H2O2 formed a highly branched root system with abundant lateral roots and a shorter primary root. Monitoring of the auxin responsive DR5::GUS indicated that auxin accumulation decreased in lateral root primordia (LRP) and emerging lateral root tips. In addition, polar auxin transport, including both basipetal and acropetal transport modulated by AUX1 and PIN protein carriers, was involved in the process. Taken together, our results suggest that H2O2 could regulate plastic RSA by perturbing polar auxin transport as a means of modulating the accumulation and distribution of auxin.

Transformerless Cascaded AC-DC-AC Converter for Multiphase Propulsion Drive Application

Tao, Xing-Hua,Xu, Lie,Song, Yi-Chao,Sun, Min Journal of International Conference on Electrical 2012 Journal of international Conference on Electrical Vol.1 No.3

A transformerless converter suitable for multiphase drive application is presented in this paper. The topology employs a cascaded H-bridge rectifier as the interface between the grid and multi inverters which drive the multiphase motor. Compared with the conventional structure, the new topology eliminates the input transformer and also has the advantages such as four quadrant operation, simple configuration, low cost, high efficiency, and so on. The control strategies for the grid-side cascade H-bridge rectifier and the motor-side inverter are studied accordingly. Based on the multi-rotational reference frame, modular control scheme is developed to regulate the multiphase drive system. Simulation results show the proper operation of the proposed topology and the corresponding control strategy.

Analysis of Localized Surface Plasmon Resonance in Ag/ITO/CdS/SiO2 Multilayered Nanostructured Composite

Chao Liu,Jingwei Lv,Famei Wang,Qiang Liu,Haiwei Mu,Tao Sun,Qiang Liu,Paul K. Chu 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2015 NANO Vol.10 No.8

Multilayered nanoshells have attracted much attention due to their unique optical, electronic and magnetic properties. In this work, numerical calculation using discrete dipole approximation (DDA) is conducted to investigate the quad-layered metal nanoshell consisting of a particle with a dielectric silica (SiO2) core, inner cadium sulfide (CdS) shell, middle indium tin oxide (ITO) shell and outer metal silver (Ag) shell. The phenomenon is interpreted by plasmon hybridization theory and the Ag–ITO–CdS–SiO2 multilayered nanoshells are studied by extinction spectra of localized surface plasmon resonance. The variation in the spectrum peak with nanoparticle thickness and refractive index of the surrounding medium is derived. The electric field enhancement contour around the nanoparticles under illumination is analyzed at the plasmon resonance wavelength. The |ω-->, |ω+->, and |ω-+> modes red-shift with the refractive index of the surrounding medium and increase in the layer thickness causes either blue-shift or red-shift as shown by the extinction spectra. The mechanism of the red-shift or blue-shift is discussed. The |ω--> blue-shifts and furthermore, the |ω-+> and |ω+-> modes of the Ag coated multilayered nanostructure are noticeable by comparing the extinction efficiency spectra of the Au–ITO–CdS–SiO2 and Ag–ITO–CdS–SiO2 multilayered nanoshells.

COMPUTING B-SPLINE SURFACES ON TRANSPUTER NETWORKS

Chao Deng,Mong Tao Shen 대한전자공학회 1992 대한전자공학회 Conference Vol.1992 No.2