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이양숙(Yang-Suk Lee),홍창균(Chang-Kyun Hong),서수정(Soo-Jung Seo),김남우(Nam-Woo Kim) 한국식품영양과학회 2010 한국식품영양과학회지 Vol.39 No.8
식용 및 약용으로 사용되고 있는 자귀나무(A. julibrissin) 의 줄기와 잎을 대상으로 새로운 기능성식품이나 의약품의 소재로써 영양학적 가치 및 활용 가능성을 알아보고자 일반성분, 당, 수용성 단백질, 폴리페놀과 플라보노이드, 무기질 그리고 유리아미노산 및 아미노산 유도체의 함량을 분석하였다. 자귀나무의 줄기는 잎보다 탄수화물 함량은 높았으나 그 외의 조단백질과 조지방, 조회분은 잎에서 더 높았다. 수용성 단백질은 줄기에서 229.57 ㎎%, 잎은 1,073.59%였으며, 폴리페놀 화합물은 각각 446.67 ㎎%와 2,583.33 ㎎%, 플라보노이드는 16.36 ㎎%와 2,234.75 ㎎%를 함유하였다. 무기질은 줄기 1,656.56 ㎎%, 잎 2,018.71 ㎎%로 Ca와 K,Mg의 함량이 높았으며, 전체 무기질 함량의 99%를 차지하였다. 총 17종이 분리 동정된 유리아미노산은 줄기 2,977.28㎎%, 잎 8,840.66 ㎎%로 proline이 많았으며, 잎에서는 특히 cysteine이 비교적 많았다. 아미노산 유도체는 줄기에서 11종 263.53 ㎎%로 γ-aminoisobutyric acid(108.74 ㎎%), 잎에서는 13종 696.47 ㎎%로 phosphoserine(253.90 ㎎%) 이 함량이 높았다. 자귀나무 줄기보다는 잎이 조회분, 조지방뿐만 아니라 당과 무기질, 유리아미노산의 함량도 더 높았으며, 생리활성을 나타내는 물질로 알려져 있는 폴리페놀은 약 5.8배, 플라보노이드는 약 130배 이상 자귀나무 잎이 줄기보다 더 많았다. 이상의 결과 식용과 약용으로 사용되는 자귀나무는 잎이 줄기보다 생리학적 가치뿐만 아니라 식품영양학적으로도 매우 우수한 것으로 분석되었으며, 이를 이용한 기능성식품이나 의약품 등의 소재로써 활용 가능성 매우 높은 것으로 판단된다. This research analyzed useful nutritional component data in stems and leaves of the Albizzia julibrissin for proximate composition, contents of soluble protein, reducing sugar, free sugar, total polyphenol compound, mineral, free amino acid, and amino acid derivative. The carbohydrate contents of A. julibrissin stems and leaves were 71.08% and 64.85%, and crude protein contents were 8.05% and 11.38%, respectively. In addition, the crude fat contents were 2.95% and 3.03%, and the crude ash contents were 8.98% and 9.07%, respectively. Reducing sugar and free sugar in stems were 711.80 ㎎% and 15.66 ㎎%, and 1,422.83 ㎎% and 40.3 ㎎% in leaves, respectively. The contents of soluble protein were 229.57 ㎎% in stems and 1,073.59 ㎎% in leaves. The polyphenol and flavonoid compounds were 446.67 ㎎% and 16.36 ㎎% in stems, and 2,583.33 ㎎% and 2,234.75 ㎎% in leaves. In the results of mineral analysis, the content of Ca was the highest in stems as 933.07 ㎎% followed by K (605.07 ㎎%). The content of K was also the highest (1,489.53 ㎎%) in leaves, and Ca was 287.73 ㎎%. The free amino acid content of A. julibrissin stems was 2,977.28 ㎎%, and 8,840.66 ㎎% in leaves. Total contents of amino acid derivative were 263.53 ㎎% in stems and 696.47 ㎎% in leaves.
홍창균,안유배,김설혜,우영식,이성구,고승현,송기호,윤건호,강무일,차봉연,이광우,손호영,강성구 대한내분비학회 2001 Endocrinology and metabolism Vol.16 No.4
Pheochromocytoma is usually associated with a combination of various clinical manifestations caused by the overproduction of catecholamines. It is frequently accompanied by impaired glucose tolerance operating through 2 - and - adrenergic mechanisms. A 41-year-old-woman was admitted to the hospital because of poorly-controlled diabetes mellitus and hypertension. She had suffered intermittent paroxysmal attacks of headache and chest discomfort and had been treated intermittently over a 2 year period for diabetes mellitus and hypertension. At admission, the levels of serum epinephrine, norepinephrine urinary excretion of total metanephrine, and VMA were all abnormally elevated. Adrenal CT showed a well-defined, homogenous mass in the right adrenal region and the tumor was diagnosed as pheochromocytoma. After tumor resection, the increased blood level of catecholamines, the urinary excretion of total metanephrine, and VMA were normalized, as was the hyperglycemia state. Diabetes mellitus of the patient was considered permanently resolved after tumor removal by the result of glucose tolerance in 75 g oral glucose tolerance test
Pneumobilia 가 동반된 간세포암종에서 간동맥 화학색전술 후 비암성 간 내에 발생한 간농양 1 예
김영철,이성구,박영민,이소영,김용균,정규원,배시현,김부성,정연주,선희식,유수은,박두호,변병훈,최종영,신제현,홍창균 대한간학회 2001 Clinical and Molecular Hepatology(대한간학회지) Vol.7 No.2
Transcatheter arterial chemoembolization (TACE) is widely used to treat inoperable hepatocellular carcinoma and metastatic tumor of the liver. Among the complications occurring after TACE, liver abscess formation in HCC is a fatal complication. The reported incidence of this complication ranges from O% to 3.3%. Moreover, liver abscess formation in non - tumorous parenchyma is very rare. The pathogenic mechanism of this complication has been linked to several factors but retrograde enteric bacterial contamination of the biliary tract appears to be the most commonly implicated cause. The major risk factors of the biliary tract infection are pneumobilia, portal vein thrombosis, bilo - enteric anastomosis and biliary obstruction. We report a rare case of liver abscess formation in non - tumorous liver parenchyma after TACE for the treatment of hepatocellular carcinoma in a patient with pneumobilia(Korean J Hepatol 2001;7:189-194)