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      • SCISCIESCOPUS

        Water harvest via dewing

        Lee, Anna,Moon, Myoung-Woon,Lim, Hyuneui,Kim, Wan-Doo,Kim, Ho-Young American Chemical Society 2012 Langmuir Vol.28 No.27

        <P>Harvesting water from humid air via dewing can provide a viable solution to a water shortage problem where liquid-phase water is not available. Here we experimentally quantify the effects of wettability and geometry of the condensation substrate on the water harvest efficiency. Uniformly hydrophilic surfaces are found to exhibit higher rates of water condensation and collection than surfaces with lower wettability. This is in contrast to a fog basking method where the most efficient surface consists of hydrophilic islands surrounded by hydrophobic background. A thin drainage path in the lower portion of the condensation substrate is revealed to greatly enhance the water collection efficiency. The optimal surface conditions found in this work can be used to design a practical device that harvests water as its biological counterpart, a green tree frog, Litoria caerulea, does during the dry season in tropical northern Australia.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/langd5/2012/langd5.2012.28.issue-27/la3013987/production/images/medium/la-2012-013987_0006.gif'></P>

      • KCI등재

        어머니의 분리불안과 어린이집에 대한 신뢰가 영아의 어린이집 적응에 미치는 영향

        문애현(Moon, Ae-Hyun),조안나(Cho, Anna) 한국열린유아교육학회 2018 열린유아교육연구 Vol.23 No.4

        본 연구는 어머니의 분리불안과 어린이집에 대한 신뢰가 영아의 어린이집 적응에 미치는 영향을 알아보는 데 있다. 이를 위해 경기도 Y시에 소재한 국공립·직장·민간·가정 4개 유형의 어린이집 만1세~2세 영아와 그들의 어머니 154명, 담임교사 58명에게 구조화된 설문지를 통하여 자료를 수집하였다. 연구결과를 도출하기 위해 빈도분석, t-test 및 일원배치 분산분석, 피어슨 상관분석, 다중회귀분석을 실시하였고, 그 결과 첫째 어머니의 분리불안은 취업모보다 전업주부의 경우가 더 높았다. 둘째, 어린이집에 대한 신뢰도는 어머니가 대학졸업의 고학력일 경우 더 높았다. 셋째, 어머니의 분리불안과 어린이집에 대한 신뢰는 적응에 유의한 영향이 나타나지 않았으나, 어머니의 분리불안은 적응 하위 요소인 ‘긍정적 감정’에 부적상관이 나타났고, 신뢰 하위 요소 중 ‘보육성과 인식’은 적응 하위 요소인 ‘친사회적 행동, ‘또래관계’와 정적상관이 나타났으며, ‘관계역량’은 ‘자아강도’와 부적상관관계를 나타냈다. 본 연구의 결과는 영아기 자녀의 어머니가 갖는 분리불안의 최소화와 기관에 대한 신뢰도 향상을 위한 보육 및 교육환경을 조성하는 데 기초적 자료가 될 수 있을 것으로 기대한다. The purpose of this study is to investigate the effect of maternal separation anxiety and reliability toward child-care center on infant’s adaptation in child-care center. The data were collected by survey from 154 children of age 1 to 2, their mothers and their 58 teachers in four types of child-care centers, which are national public, workplace, private, and household, located in Y city, Gyeonggi-do. For the result, frequency analysis, t-test and one-way ANOVA, Pearson"s correlation coefficient, and multiple regression analysis were used, and the main results of this study were as follows; first, mothers’ separation anxiety was higher for housewives than working mothers. Second, the degree of reliability toward child-care center was higher for the mothers with higher level of education. Third, although there were no significant effect from maternal separation anxiety and reliability in child-care centers on infants’ adaptation in child-care center, there was a negative correlation between maternal anxiety and an adaptation sub-factor, positive emotion, and a reliability sub-factor, child care performance perception, showed a positive correlation with both an adaptation sub-factor, pro-social behavior and peer relationship. Additionally relational competence of reliability showed a negative correlation with ego-strength. The results of this study are expected to be fundamental data to construct educational environment in which mothers of infants may minimize separation anxiety and improve their reliability toward child-care center.

      • KCI등재후보

        소아 폼페병 환자의 임상 양상

        조안나(Anna Cho),정고운(Go Un Jeong),임병찬(Byung Chan Lim),박지윤(Jee Yoon Park),문진화(Jin Hwa Moon),채종희(Jong Hee Chae),황용승(Yong Seung Hwang),김기중(Ki Joong Kim),황희(Hee Hwang) 대한소아신경학회 2007 대한소아신경학회지 Vol.15 No.1

        목 적 : 폼페병은 리소솜 안에서 글리코겐의 분해에 작용하는 효소의 결핍에 의해 발생하는 대사성 근병증으로 글리코겐 기질이 표적 장기에 축적되는 공통의 질병 진행 경과를 가지나 효소의 결핍 정도에 따라 다양한 임상양상 및 중증도를 보인다. 최근 효소 치환 치료로 이 질환의 조기 진단과 치료의 중요성이 강조되고 있는바 근육 조직검사를 통해 진단된 소아 폼페병 환자의 임상 양상을 조사함으로써 이 질환의 임상적 특성에 대해 알아보고자 하였다. 방 법: 서울대학교 어린이병원 소아과에서 근육조직검사 및 효소검사를 통해 폼페병으로 진단된 환자에 대해 임상 양상과 각종 혈액 검사 소견, 심초음파 소견 및 근육 조직 검사 소견을 조사하였다. 결 과 : 폼페병 환자들이 처음 증상이나 징후를 보인 연령은 평균 2.2세였고 진단 시 연령은 5.3세로 조기 진단이 어려움을 알 수 있었다. 환자들은 운동 발달 지연, 근 위약, 근 긴장도 저하, 심비대, 비후성 심근증, 간비대, 반복적 호흡기 감염 등을 보였고 그 발현 정도는 매우 다양하였다. 혈액 검사에서 대부분 경도의 간 효소수치 상승을 보였으며 CK와 LD도 다양한 정도의 상승을 보였다. 근육 조직검사에서는 특징적인 근 섬유의 퇴화와 글리코겐 침착이 관찰되었다. 결 론 : 폼페병은 다양한 연령에서 다양한 임상발현을 하는 질환으로 특히 영아에서는 빠르게 진행하는 심근증으로 조기에 사망에 이르는 치명적인 질환이다. 근육 조직검사는 특징적인 글리코겐 침착 소견을 보여 이 질환의 진단에 매우 유용한 검사이다. 최근 효소 치환 치료로 인해 폼페병의 조기 진단과 치료가 강조되고 있는 바 폼페병의 다양한 임상 양상을 이해하고 근육 조직 검사 및 효소 검사를 조기에 시행, 진단하는 것이 병의 경과를 완화시키고 예후를 호전시키는데 중요할 것으로 사료된다. Purpose : Pompe disease is one of the glycogen storage diseases caused by a deficiency of acid α-glycosidase. This enzyme defect results in lysosomal glycogen accumulation in many tissues and shows a various spectrum of clinical features from early infantile hypotonia to mild weakness. For the investigation of the clinical characteristics of Pompe disease, we reviewed 6 cases of childhood Pompe disease diagnosed by muscle biopsy and acid α-glycosidase assay. Methods : We reviewed the medical records of 6 childhood Pompe disease patients in Seoul National University Childrens Hospital, retrospectively from January 2001 to October 2006. Results : The age of the symptom onset was 1 month to 11 years(mean 2.2 years) and the diagnosis was made at the age of 8 months to 14 years(mean 5.3 years). The patients showed delayed motor development, motor weakness, hypotonia, cardiomegaly, hypertrophic cardiomyopathy, hepatomegaly, recurrent pulmonary infections but the severity was very diverse. Liver transaminase and CK levels were elevated in all of the patients. Their muscle biopsy showed the characteristic accumulation of purple colored glycogen granules and the degeneration of myofibers. Conclusion : Childhood Pompe disease had various clinical features and severities depending on the age of onset, organ involvement and the rate of progression. Enzyme replacement therapy may modify the disease courses, so we need to diagnose earlier for the treatment at an optimal time.

      • What Explains the Idiosyncratic Volatility in the Korean Stock Market?

        Sangkyu Lee,Anna Moon 한국재무학회 2013 한국재무학회 학술대회 Vol.2013 No.05

        Using the Fama and French (1993) three-factor model, this paper provides an explanation for the variation of idiosyncratic return in the Korean stock market over the period of 1990-2012. There had been an upward trend until 1999 in idiosyncratic volatility and its trend has been reversed afterwards. Our analysis yields three main results. Firstly, it appears that all four explanatory variables, two fundamentals related variables of the variance of return on equity and a proxy of growth options and two trading volume related variables of trading volume and foreign ownership ratio, explain considerable proportion of idiosyncratic return variation. Most interestingly, foreign investors have stabilizing effect on firm-specific risk in the Korean stock market. Secondly, a firm’s characteristics such as size and export orientation exert some influence on idiosyncratic volatility. Lastly, the absolute and relative explanatory powers of the four explanatory variables vary through time and diminish as the sample period ends, implying the need to search for further explanatory variables.

      • SCISCIESCOPUS
      • SCIESCOPUSKCI등재

        Eccrine Porocarcinoma: A Multicenter Retrospective Study with Review of the Literatures Reported in Korea

        ( Hee Joo Kim ),( Anna Kim ),( Kyung-chul Moon ),( Soo Hong Seo ),( Il-hwan Kim ),( Aeree Kim ),( Yoo Sang Baek ) 대한피부과학회 2020 Annals of Dermatology Vol.32 No.3

        Background: Eccrine porocarcinoma (EPC) is a rare malignant cutaneous adnexal tumor. Other than several scattered case reports, no comprehensive review on EPC has been conducted in Korea. Objective: To clinicopathologically review all EPC cases from our institutions as well as those reported in Korea. Methods: Medical records and histopathological slides of EPC cases in the skin biopsy registries of our institutions were retrospectively reviewed. Additionally, EPC cases reported in Korea before June 2019 were retrieved by searching the PubMed, KoMCI, KoreaMed, and KMbase databases. Results: Nine EPC cases from our institutions were included in the study. In addition, 27 reports of 28 patients with EPC were reported in Korea. A total of 37 patients with EPC were identified, consisting of 19 males (male:female ratio, 1.06:1; mean age at diagnosis, 65.6 years). The most common site of primary tumor was the head and neck (29.7%). Wide excision was the most common (78.4%) treatment method. Initial metastasis work-up imaging studies were performed in 18 patients (48.6%), and metastasis was confirmed in eight patients (21.6%). Conclusion: EPC is a rare cutaneous carcinoma in Korea. EPC usually affects elderly patients, with no sexual predilection. Due to possible metastasis, careful diagnosis and appropriate metastasis workups are warranted in EPC. (Ann Dermatol 32(3) 223∼229, 2020)

      • KCI등재SCOPUSSCIE

        Structure-Based Insight on the Mechanism of N-Glycosylation Inhibition by Tunicamycin

        Danbi Yoon,Ju Heun Moon,Anna Cho,Hyejoon Boo,Jeong Seok Cha,Yoonji Lee,Jiho Yoo Korean Society for Molecular and Cellular Biology 2023 Molecules and cells Vol.46 No.6

        N-glycosylation, a common post-translational modification, is widely acknowledged to have a significant effect on protein stability and folding. N-glycosylation is a complex process that occurs in the endoplasmic reticulum (ER) and requires the participation of multiple enzymes. GlcNAc-1-P-transferase (GPT) is essential for initiating N-glycosylation in the ER. Tunicamycin is a natural product that inhibits N-glycosylation and produces ER stress, and thus it is utilized in research. The molecular mechanism by which GPT triggers N-glycosylation is discussed in this review based on the GPT structure. Based on the structure of the GPT-tunicamycin complex, we also discuss how tunicamycin reduces GPT activity, which prevents N-glycosylation. This review will be highly useful for understanding the role of GPT in the N-glycosylation of proteins, as well as presents a potential for considering tunicamycin as an antibiotic treatment.

      • SCISCIESCOPUS
      • SCISCIESCOPUS

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