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소아천식 및 소아 만성 호흡기질환군에 대한 히스타민가입 인혈청 면역글로블린의 치료효과와 치료전후의 혈청 IgE , IgG 및 총 호산구수의 변동
이기영,김규언,정병주 대한천식알레르기학회 1989 천식 및 알레르기 Vol.9 No.3
The therapeutic effect of Histamine gammaglobulin was evaluated in 101 patients with atopic asthma(41 cases), non-atopic asthma(38 cases) and chronic respiratory group(22 cases). The effect was evaluated on the criteria by the Japanese Pediatrics Allergy Study Group after subcutaneous injection of Histamine gammaglobulin weekly for 9 weeks. In cases where Histamine-gammaglobulin therapy was effective for asthmatic children, IgE, IgG serum level and total eosinophil count were compared before and after therapy. Re-evaluation of therapeutic effect was done 1-2 years after therapy for non-atopic asthmatic children and chronic respiratory group responsive to treatment. The results were as follows'. 1. There was an overall therapeutic effect in 60 cases(59.4%) among 101 cases,' the effects were 63.4%, 52.6 % and 63.6% in atopic, non-atopic asthmatic children and chronic respiratory group respectively. 2. In the effective cases of atopic asthmatic children, the degree of effect was excellent in 23 1%, good in 34.6% and fair in 42.3%, and in nonatopic asthmatic children it was excellent in 40.0%, good in 35.0% and fair in 25.0%.