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        Clinical Outcomes of Ductal Carcinoma In Situ of the Breast Treated with Partial Mastectomy without Adjuvant Radiotherapy

        황승현,이희대,정준,안성귀,이학민 연세대학교의과대학 2012 Yonsei medical journal Vol.53 No.3

        Purpose: Some recent trials suggest that postoperative adjuvant radiotherapy (RT) may be safely omitted after breast-conserving surgery (BCS) for some patients with ductal carcinoma in situ (DCIS). In this study, we reviewed clinical outcomes of patients with DCIS treated with partial mastectomy (PM) without adjuvant RT. Materials and Methods: Medical records of 28 patients (29 breasts) with DCIS who were treated with PM, but without RT, between April 1991 and December 2010 were retrospectively analyzed. Based on established criteria (2.0 cm or less in size and no comedonecrosis), 18 patients were treated without RT after PM. Seven patients (8 breasts) who did not receive RT due to refusal were also included in this study. Three other patients were excluded because data concerning comedonecrosis were not available. Results: For the 25 patients included in this study, the mean age of the 18 patients who met the criteria was 47.9±6.2 years, and 47.6±12.7 years for the 7 patients who did not. The mean sizes of the primary tumors were 0.6±0.4 cm and 0.9±0.3 cm, respectively, in these two groups. Among these 25 patients (26 breasts) treated without RT, we observed no ipsilateral breast tumor recurrence or mortality within a mean follow-up of 84 months. Conclusion: Based on this small number of cases, patients with DCIS, who were selected for tumor size less than 2 cm and absence of comedonecrosis, may be treated successfully with BCS; adjuvant RT may be omitted.

      • 출산 전후기에 진단된 무증상 부신 종괴의 치료

        황승현,임준섭,오정탁,김명준,한석주,최승훈,Hwang, Seung-Hyun,Lim, Jun-Sup,Oh, Jung-Tak,Kim, Myung-Joon,Han, Seok-Joo,Choi, Seung-Hoon 대한소아외과학회 2004 소아외과 Vol.10 No.2

        Recently, the incidence of perinatally detected asymptomatic adrenal gland masses has increased because of widespread use of radiological diagnostic tools. However, optimal treatment of these masses has not been determined. The aim of this study is to elucidate the treatment guideline of perinatally diagnosed adrenal gland masses. The authors retrospectively reviewed the medical records of the 11 patients with asymptomatic adrenal gland mass, detected perinatally, between 1999 and 2004. Six cases were detected by prenatal ultrasound and 5 cases were incidentally detected by postnatal ultrasound. Six patients (surgery group) underwent mass excision. The pathologic diagnoses were neuroblastoma (n=4), adrenocortical adenoma (n=1) and adrenal pseudocyst (n=1). The indications for operation were suspicion of neuroblastoma (n=5) or absence of size decrease during observation (n=1). Three of the 5 suspicious cases of neuroblastoma and one case under observation were proven to be neuroblastoma. There was no surgical complication in the urgery group. All neuroblastoma patients have been well during the follow up period ($24.4{\pm}14.4$ month) without evidence of recurrence. Five cases (observation group) were closely observed because of the benign possibility or size decrease in follow up ultrasound. During the observation period ($39{\pm}21$ week), 4 cases showed complete spontaneous resolution and 1 case showed markedly decreased size of the mass but could not be followed up completely. Surgical resection of the perinatally diagnosed asymptomatic adrenal gland mass is a safe treatment method especially in case of suspicion of neuroblastoma, but closed observation can be applied.

      • KCI등재

        다크 모드에서 모바일 시각정보요소 카드의 시각적 인지도와 피로도 연구

        황승현,이현진 한국색채학회 2022 한국색채학회 논문집 Vol.36 No.1

        This study set out to analyze colors of high visual recognition and low visual fatigue at the tone level and their saturation scope in a mobile interface card fit for the dark mode in low illuminance, as well as propose a color scheme. For these purposes, the study analyzed color palettes for the dark mode in the Android system, then we tested color scheme samples of card elements in app layout to collect factors affecting visual recognition and fatigue. The survey answers with Likert and ordinal scales of the test were analyzed to prove study hypotheses. The findings show that the tone levels and colors had an effect on the visual recognition and fatigue items except for the items of color understanding and the items of composition understanding based on Likert scale survey. The analysis results identified a couple of colors of high visual recognition including yellow at the tone levels of 50, 100, and 300, blue at the tone levels of 50 and 300, and purple at the tone level of 100. Blue had low visual fatigue, and so did teal and purple at the tone level of 50. Both blue and purple had a low level of ocular discomfort like teal, which recorded lower visual fatigue than them. The analysis results identified purple and teal at the tone level of 100, and purple was found in all the items of visual fatigue. Yellow and teal were analyzed as the colors with the low visual fatigue at the tone level of 300. Yellow had a low level of ocular discomfort like blue, which recorded a lower level of ocular discomfort than yellow. Blue and yellow of high visual recognition were high in saturation, and teal and purple of low visual fatigue were lower in saturation than blue and yellow.

      • 방사선 가교 기술을 이용한 유효성분 방출력이 우수한하이드로겔 제조 및 특성 분석

        황승현,안성준,박종석,정성인,권희정,임윤묵,이동윤 한국방사선산업학회 2015 방사선산업학회지 Vol.9 No.4

        Typical radiation cross-linked hydrogels has the characteristic that high water content,but low emission efficiency of active ingredients. Therefore, the hydrogel was prepared by theaddition to collagen, which is closely related to the formation of skin wrinkles in biocompatibilityand highly water-soluble carboxymethyl cellulose sodium salt (CMC) in order to preparationof hydrogels has excellent emission efficiency of active ingredients. Hydrogels were preparedby dissolving CMC and collagen each of 0.5%, 10% concentration in deionized water. Then,prepared hydrogels are performed by gamma-radiation at 1, 3, 5 kGy irradiation dose. The resultsshowed that the gel fraction of after irradiated 3 kGy hydrogel was higher than before irradiatedgelation as long as the 55.3%. The swelling rate of irradiated 3 kGy hydrogel was lower than thenon-irradiated sample. The compressive strength of 3 kGy irradiated hydrogel was the highest. The visco-elastic did not show any significant differences, even after irradiation. The CMChydrogel in this study suggested a potential use as a material for the mask pack for improvedemission efficiency of the active ingredient and anti-wrinkles.

      • KCI등재

        The Business of Theatre in Caroline London: The Tamer Tamed and the King’s Men

        황승현 한국고전중세르네상스영문학회 2019 중세근세영문학 Vol.29 No.1

        This paper delves into the relationships between the three divisions of the business of theatre associated with the 1633 King’s Men production of The Tamer Tamed. A connection between the revival and revision of Fletcher’s Jacobean text, The Tamer Tamed, and the preferences of the various types of audiences are shown as a reaction initiated by the playing troupe’s finances, stemming from a combination of public theatre performances, private theatre performances, and patronage. The moderating effect of censorship by the Master of Revels and the anti-Catholic leanings of London Puritans during Charles I’s reign are also interwoven into the discussion. To examine the business of theatre in this period, the roles of production, consumption, and supervision can be considered through the interactions of three distinct groups: producers (acting companies and playwrights), consumers (noble patrons and public audience), and supervisors (Master of Revels, court, and church).

      • KCI등재

        Painting Lady Macbeth as a Female Villain: Don’t Do Her Like That

        황승현 한국중세근세영문학회 2017 고전·르네상스 영문학 Vol.26 No.2

        The crime of premeditated murder is at the heart of Shakespeare’s The Tragedy of Macbeth. It is questionable how to speak about this crime and interpret her actions and motives in light of the given information presented in Shakespeare’s text. She seems to have a conscience. Shakespeare leads us to think that she commits suicide because she is so bothered by her heinous actions. Even though Lady Macbeth does not wield the murder weapon herself, she still has blood on her hands. Over the centuries actors have portrayed her as a co-conspirator or a wife who bewitched her husband. If the society at the time wanted to honor male dominance, then Lady Macbeth as an evil wife who is not submissive to King Duncan or her husband is the favored plot path. So echoing the narrative of male-dominance, Lady Macbeth could merely be labeled as an evil character. However, some have added the aspect of humanity behind the label of an evil woman. In various historical times, how Lady Macbeth was interpreted by actors depended on the cultural biases of the era and the kind of personal connection the actor made to the character. This essay looks at the differentiation in interpretation of this female character involved in criminal behavior concerning gender and biased attitudes of the historical time and of a sense of familiarity, or lack of, between the actor and essence of the character.

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