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Second-trimester fetal genetic ultrasonography to detect chromosomal abnormalities
홍성은 대한의학유전학회 2014 대한의학유전학회지 Vol.11 No.2
Genetic ultrasonography refers to the evaluation of risk of chromosomal abnormalities via various soft sonographic markers. Although the maternal serum test is the primary screening method for chromosomal abnormalities, genetic ultrasonography isalso widely used and can help increase detection rates. To date, many soft markers, including choroid plexus cysts, echogenicintracardiac foci, mild ventriculomegaly, nuchal fold thickening, echogenic bowel, mild pyelectasis, short femur and humeruslength, and absent or hypoplastic nasal bone, have been reported. An aberrant right subclavian artery was the most novel softmarker introduced. Because these soft markers involve diverse relative risks of chromosomal abnormalities, it is difficult toapply them to clinical practice. To optimize the efficacy of genetic ultrasonography, it is important to understand the preciserelative risks of chromosomal abnormalities innumerous soft markers and integrate these risks with each other and the resultsof maternal serum screening.
홍성은,김브라이언,공준석,안정민 대한이비인후과학회 2023 대한이비인후과학회지 두경부외과학 Vol.66 No.5
Seborrheic keratosis is a common type of epidermal tumor caused by benign proliferation ofimmature keratinocytes. They usually appear as well-demarcated, slightly raised brownishpatches or plaques. They are typically slow-growing, can increase in thickness over time, andrarely resolved spontaneously. Seborrheic keratosis is frequently found on sun-exposed skinsurfaces such as the trunk, extremities, head and neck of elderly people. However, it is rare tofind these lesions in the auricle or external auditory canal. In addition, seborrheic keratosis isoften distinguished as a benign tumor, but there can be some morphological overlap with oth-er malignant skin lesions. Herein, we report, along with a literature review, a case of seborrhe-ic keratosis in a patient who presented with a mass in the left cavum concha with a sudden in-crease in size.
홍성은,김브라이언,이명철,최익준 대한이비인후과학회 2023 대한이비인후과학회지 두경부외과학 Vol.66 No.11
A plunging ranula is a pseudocyst in the neck that originates from the sublingual gland in theprocess of mucus extravasation and herniation. It has been widely suggested that the cause of aplunging ranula is due to a congenital predisposition involving the dehiscence of the mylohyoidmuscle, racial predisposition and previous oral trauma. Even though unilateral plunging ranulais rare, and bilateral plunging ranulas are even more rare. We recently experienced a case of bi-lateral plunging ranula in a 27-year-old male. He presented with a right-sided submandibularswelling and was diagnosed with a plunging ranula and right ranula excision and sublingualgland excision was performed. He visited the outpatient department with contralateral subman-dibular swelling after 18 months of operation. Under the diagnosis of left plunging ranula, heunderwent surgery in the same way as before. We suggest that all patients with a unilateralplunging ranula, although rare, should be considered for the possibility of developing contralat-eral diseases.
폐쇄성 수면무호흡증과 만성 어지럼의 연관성: 국민건강영양조사 2019-2021
홍성은,김브라이언,이병철,이명철,최익준,안정민 대한이비인후과학회 2023 대한이비인후과학회지 두경부외과학 Vol.66 No.12
Background and Objectives The present study was aimed to investigate whether chronicdizziness is associated with obstructive sleep apnea (OSA) in Korean adults. Subjects and Method We analyzed data from the 2019-2021 Korea National Health andNutrition Examination Survey and enrolled 2323 participants over the age of 40 who complet-ed the sleep health and dizziness survey. Participants were assessed for the risk of OSA usingthe STOP-Bang questionnaire and then classified into three groups: low-, intermediate-, andhigh-risk. Logistic regression analyses were used to identify the relationship between chronicdizziness and OSA. Results The intermediate-, high-, and intermediate/high-risk groups comprised older par-ticipants with a higher proportion of male and higher body mass index compared to the low-risk groups (all p<0.001). They also had higher rates of current smoking, high-risk alcoholconsumption, hearing loss, and a higher prevalence of anemia, stroke, hypertension, diabetes,and dyslipidemia. The risk of chronic dizziness was significantly associated with the severityof OSA. Compared to the low-risk OSA group, the risk of chronic dizziness was significantlyhigher in the intermediate- (odds ratio [OR] 2.096; 95% confidence interval [CI] 1.507-2.913),high- (OR 2.119; 95% CI 1.013-4.434), and intermediate/high risk OSA groups (OR 2.097;95% CI 1.508-2.917) after adjusting for the relevant variables. Conclusion These findings suggest that early detection and intervention of OSA may benecessary to prevent the worsening of chronic dizziness in adults.