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The Prevalence of Sarcopenia in Korean Hospitalized Elderly
허원석,백현욱,강주희,박주상,박상종,장은정,박상운,김상중,고병성,노기탁,이경한,최정아 대한노인병학회 2015 Annals of geriatric medicine and research Vol.19 No.4
Background: Sarcopenia is a syndrome characterized by the progressive loss of skeletal muscle mass and muscle strength. Although data exist on the prevalence of sarcopenia among the community-dwelling elderly, there is no systematic research on hospitalized elderly patients in Korea, in accordance with the newly developed criteria. Methods: A cross-sectional study was conducted at the Daejin Medical Center, Bundang Jesaeng Hospital, Korea, from May 2013 to March 2015. In this study, we evaluated the levels of hemoglobin, total cholesterol, serum albumin, serum prealbumin, and serum zinc. Handgrip strength was measured with a hand grip dynamometer (FT-7110). Furthermore, the skeletal muscle mass was measured by bioelectrical impedance analysis (BIA). Sarcopenia was defined by skeletal muscle mass as measured with BIA, according to the Asian Working Group for Sarcopenia. Results: Of the hospitalized elderly subjects, 40 (46.5%) had a definite diagnosis of sarcopenia and 46 (53.5%) had no sarcopenia. The prevalence of sarcopenia of the subjects was higher in males than females (males, 46.9% vs. females, 46.3%). The correlation analysis showed that the score of skeletal muscle index (SMI) was negatively correlated with age; whereas, it was positively correlated with the BMI, body weight, and serum prealbumin level. Conclusion: The results of the study showed that sarcopenia was associated with several factors, including age, BMI, serum prealbumin level, among the study subjects. Sarcopenia can be used as a sensitive predictive marker for prognosis of the hospitalized elderly.
허원석,김준철,김효신,고준성,김상훈,김현우,조수연,조강준 대한비뇨의학회 2016 Investigative and Clinical Urology Vol.57 No.6
Purpose: To investigate the change in urinary urgency and predictors of urgency improvement after holmium laser enucleation of the prostate (HoLEP) in men with benign prostatic hyperplasia (BPH). Materials and Methods: We retrospectively analyzed the medical records of patients who were treated with HoLEP for BPH and had preoperative urgency measuring ≥3 on a 5-point urinary sensation scale. Those with prostate cancer diagnosed prior to or after HoLEP, a history of other prostatic and/or urethral surgery, moderate to severe postoperative complications, and neurogenic causes were excluded. Patients who had improved urgency with antimuscarinic medication after HoLEP were excluded. We divided the patients into 2 groups based on urgency symptoms 3 months after HoLEP: improved and unimproved urgency. Improved urgency was defined as a reduction of 2 or more points on the 5-point urinary sensation scale. Preoperative clinical and urodynamic factors as well as perioperative factors were compared between groups. Results: In total, 139 patients were included in this study. Voiding parameters in all patients improved significantly after HoLEP. Seventy-one patients (51.1%) had improved urgency, while 68 (48.9%) did not show any improvement. A history of acute urinary retention (AUR) and postvoid residual were associated with postoperative urgency improvement in univariate analysis. In multivariate analysis, a history of AUR was an independent factor affecting urgency improvement. Conclusions: A preoperative history of AUR could influence the change in urgency after HoLEP surgery in patients with BPH.
허원석,채경훈,정재훈,강윤세,김연수,김석현,성재규,이병석,정현용,송규싱 대한소화기내시경학회 2005 Clinical Endoscopy Vol.31 No.6
Epithelial gastric polyps can be categorized as being either hyperplastic or adenomatous. Hyperplastic polyps accounts for 75∼90% of gastric polyps. In contrast to the adenomatous polyps, the potential of a malignant transformation of hyperplastic polyps was originally believed to be quite low (an incidence of 1.5∼2.1%), which is considerably lower than that of an adenoma of the stomach. Most of reported cases of a hyperplastic gastric polyp with a transformation to adenocarcinoma were well differentiated histopathologically. There are few reports of a hyperplastic polyp in which malignant changes developed during the endoscopic surveillance. We report a rare case of a 1.2 cm sized moderately differentiated adenocarcinoma arising in a hyperplastic polyp on the cardia in the stomach with a brief review of the relevant literature. 위용종은 위에 발생하는 흔한 양성 신생물로서 크게 과형성 용종과 선종성 용종으로 나누고 과형성 용종이 가장 흔하며 전체의 75~90%를 차지한다. 선종성 용종은 부분적 선암을 동반한 경우가 6~75%로 다양하게 보고되고 있으며, 과형성 용종은 1.5~2.1%로 낮은 것으로 알려져 있다. 따라서 선종성 용종은 전암성 병변으로 인식되어 용종 절제술의 일반적인 적응증이었으나, 과형성 용종은 자연경과 및 용종절제술의 적응 유무에 대해 아직 정립된 바가 없다. 저자들은 위 내시경 검사에서 발견한 조기위암을 수술적 치료 후 조직검사에서 중등도 분화 선암이 일부 있는 과형성 용종 1예와, 내시경 치료 후 조직검사에서 고분화 선암이 일부 있는 과형성 용종 1예를 경험하고 문헌고찰과 함께 보고한다.