Toxic shock syndrome caused by community associated methicillin resistant Staphylococcus aureus

한준우,박선희,박준홍 대한내과학회 2018 대한내과학회 추계학술대회 Vol.2018 No.1

의약품부작용보고시스템 데이터베이스를 이용한 졸피뎀 약물 유해반응 실마리 정보 검출

한준우,김선지,고영진,박병주 한국보건의료기술평가학회 2018 보건의료기술평가 Vol.6 No.1

Objectives: To detect signals of adverse drug reactions of zolpidem by data mining using the Korea Adverse Events Reporting System (KAERS) database. Methods: This study used the Korea Institute of Drug Safety KAERS Database (KIDS-KD) reported from December 1988 to December 2015 through KAERS. Among them, signals were detected by data mining on the adverse events of zolpidem. In this study, we defined a signal that satisfies all three indices: proportional reporting ratio (PRR), reporting odds ratio (ROR) and information component (IC). And we checked whether the detected signals exist in drug labels in Korea, the United States, the United Kingdom, Germany, France, and Japan. Results: A total of 3012517 adverse event-drug pairs were reported from 1988 to 2015, of which 11814 were associated with zolpidem. Fifty nine signals were satisfying the criteria (PRR, ROR, and IC). Based on this, the detected signals were compared with the drug labels of six countries. As a result, 17 signals were not included in all the drug labels of 6 countries. Schizophrenic reaction, paronychia, dry eyes, intervertebral disc disorder, duodenal ulcer, extravasation, lactation nonpuerperal, lymphoedema, carcinoma squamous, hypercalcaemia, brain neoplasm benign, colon carcinoma, colitis ulcerative, renal papillary necrosis, ovarian cyst, hyperphosphataemia, and fluid overload. Conclusion: We identified 17 new signals of zolpidem that do not exist in drug labels in six countries. However, further pharmacoepidemiological studies should be needed to evaluate the causality of the signals with zolpidem.

觀光と文化, そしてアイデンティティに關する諸議論の展開 : 人類學的省奈

韓準祐 동북아관광학회 2013 동북아관광연구 Vol.9 No.3

自己表象と創発的内省性に基づく地域アイデンティティの考察 : 由布院を事例として

韓準祐 동북아관광학회 2012 동북아관광연구 Vol.8 No.1

日本における觀光まちづくりの國策化の背景

韓準祐(Han, Jun-woo) 한국관광레저학회 2014 관광레저연구 Vol.26 No.2

발아 카무트 분말을 첨가한 식빵의 품질 특성 및 항산화 작용

윤진아,한준우,최재환,신경옥 동아시아식생활학회 2020 동아시아식생활학회지 Vol.30 No.5

The quality and antioxidant properties of bread prepared by adding germinated kamut (Triticum turanicum Jakubz) powder were analyzed. As the proportion of germinated kamut powder increased from 0% to 50%, the pH and the weight of the bread increased. Further, with increase in amount of germinated kamut powder, the volume, expansion capacity and height of the bread significantly decreased. There was no significant difference observed in the qualities of springiness and cohesiveness between the control and bread prepared with germinated kamut powder. Adhesiveness was in the control, and hardness, gumminess, chewiness, and resilience were in the bread containing 50% germinated kamut powder. The 70.5% ethanol extract of the germinated kamut powder showed high antioxidant of 2,2ʹ-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity. In conclusion, the addition of 12% germinated kamut while making bread, will result in a product of higher quality and improved antioxidant activity.

인도의 투자환경과 우리나라 기업의 대인도 투자현황 및 투자 관리 방안에 관한 연구

남경두,한준우 한국상품학회 2004 商品學硏究 Vol.0 No.31

This research is to study how Korean firms should manage FDI risks, and also to examine the various ways of the risk management when investing in India. In the case of company trait, the scale of the company, its export share and the age of the firm when investing in India do have an effect on the risk. The risk level is lower when the company is large, exports more and has a long history operating in India. As for the management of company trait, the Korean firms investing in India should assess the risk, increase export share and pay close attention to the risk at the beginning stage of the investment. In the case of industry trait, the risk is being affected by the diversification of the business, as well as the items and dispersion of production line. As for the management of industry trait, Korean firms investing in India are advised to disperse business sites and production lines, to diversify handling items as well as buying sources. In the case of investment environment trait, the risk is increased when the country risk is high, market situation is unstable and labor is unrest. As for the management of environment trait, Korean firms investing in India should acquire investment insurance, manage labor properly and adjust to the different cultures in India. It has been revealed that India's social environment such as caste, religion, and culture are very different from Korea's. As a result, it might be difficult to maintain a good relationship with an Indian business partner. India's potential is estimated to be very high, however the corruption level of government officials is also pretty high and the government's policies are unpredictable.

카무트 분말을 첨가한 머핀의 품질특성 및 항산화 작용

윤진아(Jin A Yoon),한준우(Jun-Woo Han),최재환(Jae-Hwan Choi),신경옥(Kyung-Ok Shin) 한국식품과학회 2021 한국식품과학회지 Vol.53 No.5

본 연구는 카무트를 활용하여 머핀의 품질을 향상시키고, 건강의 증진에 도움이 되고자 제품을 만들어 기초실험을 실시하였다. 카무트 분말을 첨가할수록 pH, 수분 함량, 머핀의 높이 및 반죽수율은 감소하였다. 카무트 분말을 첨가한 머핀의 색도 측정에서는 L값은 감소하였으며, a값과 b값은 증가하였다. 물성 측정결과, 카무트 첨가량이 증가할수록 머핀의 점착성과 응집성이 감소하고, 검성과 씹힘성이 증가하였다. ABTS 소거활성과 DPPH 소거활성은 탈 이온수 추출보다는 에탄올 추출에서 수치가 높았으며, 에탄올 추출 시에 농도 의존적으로 증가하였다. 따라서 본 연구를 종합해 볼 때, 개인의 기호도에 따라 머핀을 만들 때, 카무트의 첨가량이 달라질 수 있으나 이화학적 분석, 항산화 활성 등을 고려할 때, 카무트 분말의 첨가량은 10-15%가 가장 적당할 것으로 판단된다. In this study, basic experiments were conducted to improve the quality of muffins using kamut (Triticum turanicum Jakubz) for making products to help improve human health. Kamut powder addition decreased the pH, moisture content, muffin height, and dough yield. Chromaticity measurement of muffins with added kamut powder showed decreased L value, increased a value, and increased b value. Measurement of physical properties showed that the tackiness and cohesiveness of muffins decreased with increasing amounts of added kamut powder, along with increased gumminess and chewiness. ABTS and DPPH scavenging activities were higher in ethanol extracts than in deionized water extracts. Therefore, when making muffins, it is judged that 10 to 15% of kamut powder is most suitable in consideration of physicochemical analysis and antioxidant activity.

인도의 투자환경과 우리나라 기업의 대인도 투자현황 및 투자 관리 방안에 관한 연구

남경두(Nam Kyung-Doo),한준우(Han Joon-Woo) 한국상품학회 2004 商品學硏究 Vol.- No.31

This research is to study how Korean firms should manage FDI risks, and also to examine the various ways of the risk management when investing in India. In the case of company trait, the scale of the company, its export share and the age of the firm when investing in India do have an effect on the risk. The risk level is lower when the company is large, exports more and has a long history operating in India. As for the management of company trait, the Korean firms investing in India should assess the risk, increase export share and pay close attention to the risk at the beginning stage of the investment. In the case of industry trait, the risk is being affected by the diversification of the business, as well as the items and dispersion of production line. As for the management of industry trait, Korean firms investing in India are advised to disperse business sites and production lines, to diversify handling items as well as buying sources. In the case of investment environment trait, the risk is increased when the country risk is high, market situation is unstable and labor is unrest. As for the management of environment trait, Korean firms investing in India should acquire investment insurance, manage labor properly and adjust to the different cultures in India. It has been revealed that India's social environment such as caste, religion, and culture are very different from Korea's. As a result, it might be difficult to maintain a good relationship with an Indian business partner. India's potential is estimated to be very high, however the corruption level of government officials is also pretty high and the government's policies are unpredictable.

Rapid Detection of Infectious Bursal Disease Virus (IBDV) in Chickens by an Immunochromatographic Assay Kit

최강석,오진식,전우진,성환우,한준우,권준헌,이은경 한국가금학회 2010 韓國家禽學會誌 Vol.37 No.2

An immunochromatograhy (IC) based infectious bursal disease virus (IBDV) detection kit, which employed two anti-IBDV VP2 monoclonal antibodies, was evaluated for rapid diagnosis of infectious bursal disease virus (IBD). The detection limit of the IC kit for IBDV was 103.1 to 103.9 EID50/mL, indicating that the IC kit detected IBDV sensitively as same as double antigen capture ELISA but less than a RT-PCR assay. The IC kit did not detect other viral pathogens such as Newcastle disease virus, infectious bronchitis, avian influenza virus, and infectious larynotracheitis virus. When applied to tissue samples of experimental chickens died 3 or 4 days post infection after very virulent IBDV (strain Kr/D62) infection, the IC kit detected IBDV in all samples of the bursa of Fabricius, spleen, kidney, cecal tonsil and in 87.5%, 37.5% and 0% of liver, thymus and proventriculus samples. In particular, BF tissue samples showed stronger signal bands than other tissues. Positive signal was observed. All except for one thymus sample of samples having negative results by the IC kit showed the same result with DAS-ELISA but RT-PCR assay detected IBDV in some of IC kit negative samples of thymus and proventriculus. When swab samples from the bursa of Fabricius of dead chickens (n=231) on field farms were tested, the sensitivity and specificity of the IC assay relative to RT-PCR was 100% (109/109) and 97.5% (119/122), respectively and kappa value between both assay was 0.97. The kit can provide a useful aid for rapid detection of IBDV in chickens under field circumstances.