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한성용,송근암,김동욱,백동훈,이문원,김광하 대한소화기내시경학회 2018 Clinical Endoscopy Vol.51 No.2
Combined hepatocellular-cholangiocarcinoma (HCC-CC) with bile duct invasion (BDI) is rare. In unresectable cases, biliarystent placement and photodynamic therapy (PDT) are used for resolving obstructive jaundice. However, stent occlusion remainsproblematic, and PDT is expensive and time-consuming. Intraductal radiofrequency ablation (RFA) is an emerging procedure forpalliation in these patients. It has potential benefits including less expense, lower rates of severe complication, longer maintenance ofductal patency, and easier technique compared with PDT or stenting alone. We report a 67-year-old man who underwent repeatedintraductal RFA for HCC-CC and HCC with BDI, for whom bile duct patency was maintained without additional biliary procedures.
한성용,김동욱,Sung Yong Han,Dong Uk Kim 대한소화기암연구학회 2018 Journal of digestive cancer reports Vol.6 No.2
Over the past decade, circulating tumor cell have received tremendous attention as new biomarkers and basic research subjects.In recent years, research on circulating tumor DNA, exosomes and microRNAs has also been actively conducted.These circulating tumor markers have the potential to become the basis of precision medicine, such as determining the genome / immune profile, monitoring response and tolerance, and selecting therapeutic agents beyond the early diagnosis and prognosis prediction.In this article, we introduce the diagnostic methods, efficacy, meaning, and applicability of various circulating tumor markers.