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      • KCI등재후보

        교대근무기간과 심혈관계질환의 대사성 위험요인

        하미나,노상철,박정선 大韓産業醫學會 2003 대한직업환경의학회지 Vol.15 No.2

        목적: 교대근무가 심혈관계 질환의 대사성 위험요인과 관련성을 가지고 있는지를 보고자 하였다. 방법: 1개 대학병원의 226명의 간호사 및 간호조무사, 134명의 제조업체 생산직 남성 근로자를 대상으로, 혈중 콜레스테롤, 혈압, 혈당, 비만지수(BMI)및 중심성 비만지수(WHR)등을 측정하여, 교대근무 기간에 대한 회귀분석 및 로지스틱 회귀분석을 시행하여 다음과 같은 결과를 얻었다. 결과: 간호사에서는 혈중 콜레스테롤, 혈당, 혈압 및 비만지수와 교대근무 기간사이에는 유의한 양의 관련성이 관찰되지 않았고, 중심성 비만지수(WHR)와는 유의한 양의 관련성을 나타내었으며, 교대근무 기간의 상승이 중심성 비만의 위험도를 유의하게 상승시켰다. 이는 연령, 직무스트레스 및 신체적 활동도를 보정한 다변량 분석에서도 동일하였다. 남성 근로자에서는 혈압, 공복시 혈당, 비만지수가 회귀분석에서 유의한 양의 연관성을 보였으며, 고콜레스테롤혈증 및 비만의 유의한 발생위험도의 상승을 보여주었다. 결론: 본 연구 결과는 교대근무가 심혈관계 질환의 대사성 위험요인을 증가시킬 수 있음을 시사하는 것이며, 본 연구의 단면적 연구디자인으로 인하여 발생할 수 있는 '건강 교대근로자 효과'를 극복하기 위한 전향적 연구의 필요성을 제기한다고 하겠다. Objectives: To explore the relationship between shiftwork duration and metabolic risk factors on cardiovascular disease in shiftworkers. Methods: The study subjects comprised of 226 nurses, from a hospital, and 130 male workers, from a diaper and feminine hygienic material manufacturing firm. The mean ages of the male workers and nurses were 29 and 28.5 years, respectively. The fasting blood sugar, serum cholesterol, blood pressure, height and weight, waist and hip circumferences (only in nurses), and number of step for a shift as indices of physical activity were measured. Using the Korean version of Karasek's job contents questionnaire, the job stress was assessed. Information about the number of years worked, duration of shiftwork, and past medical and behavioral histories, including smoking, were obtained by self-administrated questionnaires. Linear regression analyses were performed, to show the relationships between shiftwork duration and metabolic risk factors, using simple and multivariate models, adjusted for age, smoking, job strain and physical activity. The following criteria were defined: hypertension as a SBP≥160 or a DBP≥90 mmHg at least once, hypercholesterolemia, as a serum total cholesterol≥240 ㎎/㎗, obesity as BMI(Body Mass Index)≥25㎏/㎡ and central obesity as a WHR (Waist to Hip Ratio)≥0.85; and the logistic regression analyses, according to years of shiftwork, were performed using simple and adjusted models. Results: The cholesterol and fasting blood sugar showed increasing trends, but without statistical significances, according to the increase in shiftwork duration of the male workers, although, the increases in the blood pressure and BIM were statistically significant. In the nurses, only the WHR showed a significant increase in relation to the shiftwork duration. In the logistic regression analyses, hypercholesterolemia and obesity showed significant increasing risks according to the number of years of shiftwork (OR=3.32 95%CI 1.27-8.72 and OR=3.21 95%CI 1.24-8.32 respectively) in the male workers, but hypertension showed no significance. In the nurses, only an increased central obesity was significant as a risk factor(OR=1.30 95%CI 1.05-1.62). Conclusions: These results provide evidence of the associations between shiftwork and metabolic risk factors for cardiovascular disease, although healthy shiftworker effects might exist in our cross sectional study design.

      • SCOPUSKCI등재

        소아 천식을 통해서 본 의료보험 상병 자료의 완전성 추정 : Capture-Recapture 분석방법의 적용

        하미나,권호장,강대희,조수헌,유근영,주영수,성주헌,강종원,김대성,이상일,Ha, M.N.,Kwon, H.J.,Kang, D.H.,Cho, S.H.,Yoo, K.Y.,Joo, Y.S.,Sung, J.H.,Kang, J.W.,Kim, D.S.,Lee, S.I. 대한예방의학회 1997 Journal of Preventive Medicine and Public Health Vol.30 No.2

        Objectives : The purpose of this paper is to estimate the completeness of the Korean Medical Insurance Data in childhood asthma. Methods : Capture-recapture method was used to estimate the prevalence of childhood asthma and case ascertainment rate(completeness) of Korean Medical Insurance Data using two source model, 'Korean Medical Insurance Committee Data (KMICD)' and 'Nationwide Study of Asthma and Allergies in Korean Children'. The asthma cases were restricted to those who were born from 1981 to 1989 and were identified by their Resident Register Number. Asthma cases in Korean Medical Insurance Data were defined as cases coded by ICD-9 493 and ICD-10 J45. In 'Nationwide Study of Asthma and Allergies in Korean Children', asthma cases were defined as the children who had been diagnosed asthma and had experienced symptoms of asthma during the past 12 months. The defined cases in two data sources were matched by 13 digits Resident Register Number. The numbers of matched patients in two data sources were 245 of 32,825 eligible total subjects. Chapman and Wittes' nearly unbiased estimation was used for capture-recapture analysis of two data sources. Results : Observed prevalence rate of childhood asthma was 5.3% and estimated prevalence rate by capture-recapture analysis was 11.6%. The highest prevalence rate was observed in 6-7 age group and the older the rate decreased. The completeness (the proportion of cases ascertained by KMICD to the total observed cases by two data sources) was 20.6%, and ranged form 10.8% to 28.8% by area. Conclusions : Invalid diagnosis of cases might overestimate the prevalence of child-hood asthma and might underestimate the completeness of Korean Medical Insurance Committee Data in this study.

      • Evaluation report on the causal association between humidifier disinfectants and lung injury

        하미나,이순영,황승식,박혜숙,신승수,정해관,최보율 한국역학회 2016 Epidemiology and Health Vol.38 No.-

        OBJECTIVES: As of November 2011, the Korean government recalled and banned humidifier disinfectants (HDs) from the market, because four case-control studies and one retrospective epidemiological study proved the association between HDs and lung injury of unknown cause. The report reviewed the causal role of HDs in lung injury based on scientific evidences. METHODS: A careful examination on the association between the HDs and lung injury was based on the criteria of causality inference by Hill and the US Surgeon General Expert Committee. RESULTS: We found that all the evidences on the causality fulfilled the criteria (strength of association, consistency, specificity, temporality, biologic gradient, plausibility, coherence, experiment, analogy, consideration of alternative explanations, and cessation of exposure), which proved the unknown cause lung injury reported in 2011 was caused by the HDs. In particular, there was no single reported case of lung injury since the ban in selling HDs in November 2011 as well as before the HDs were sold in markets. CONCLUSIONS: Although only a few epidemiological studies in Korea have evaluated the association between lung injury and the use of HDs, those studies contributed to proving the strong association between the use of the HDs and lung injury, based on scientific evidence.

      • KCI등재후보
      • '꿈'과 '꿈에서 깨어남'의 역동적 대립 : Hyperion, The Fall of Hyperion

        하미나 연세대학교 영어영문학회 1992 영어영문학연구 Vol.14 No.-

        항상 그 결말이 열려 있을 수밖에 없는, 따라서 미완성(fragment)을 그 특성으로 하는 Keats의 영혼 형성 체계는 긍정적인 측면에서는 현실의 부단한 변화를 무한히 수용하고 대응할 수 있는 신축성과 수용 능력을 보이지만 부정적인 측면에서는 인간을 위협하는 도전과 갈등을 항시 내포하고 있는 일시적인 해결책일 수밖에 없다. 불완전한 현실, 열려진 의식 속에서 새로운 도전, 충격에 맞설 힘과 에너지를 발휘하지 못하면 외부로부터의 개혁이나 구원을 바랄 수 없는 인간은 절망과 허무감 속에서 살아갈 수밖에 없다. 이 상태가 계속되어 인간의 의식이 이상주의의 심연에 정체될 경우 완전한 자아 상실의 위험도 초래된다. 이것이 Keats의 영혼 형성 체계가 안고 있는 가장 큰 문제점이다. 소극적 수용성은 고통을 개인적인 견지에서 벗어나 초연하게 수용하는 자세와 고통의 끊임없는 도전을 감당하게 하는 에너지의 함축을 전제한다. 그러나 Keats의 대부분의 시들은 초연한 자세와 강렬한 에너지로 현실을 인내하고 긍정하는 모습을 보이기보다 이기적인 욕망에서 벗어나지 못하여 고뇌하고 어두운 신비를 대면하여 나약해지고 좌절하는 모습을 빈번하게 보여준다. 이러한 모습은 Keats의 시세계가 주로 부정적 낭만주의(Negative Romanticism)의 단계를 표출하고 있다는 비판을 가능하게 하는 것인 한편 그가 인간 본질을 다룸에 있어 가장 진실되게 현실에 입각한 시인임을 알려준다. Keats는 실현 가능성이 없는 현실 개혁을 추구하는 '공인되지 않은 입법자' (the unacknowledged legislators of the world)14)나 거울에 비친 혁명가가 아닌, 현실에서 도피하고 싶은 인간의 이루어질 수 없는 꿈과 그 꿈이 깨어지는 아픔을 가장 잘 이해하고 치유하는 영혼의 의사가 되고자 했다.

      • KCI등재

        Cesium-137 Contaminated Roads and Health Problems in Residents: an Epidemiological Investigation in Seoul, 2011

        하미나,주영수,이원진,황승식,유상철,최경화,범은애,이지언,이윤근,임상혁 대한의학회 2018 Journal of Korean medical science Vol.33 No.9

        Background: In 2011, two roads in a residential area in Seoul were found to be contaminated with the radionuclide cesium-137 ( 137 Cs). In response to public concerns, an epidemiological study was conducted. Methods: The standardized cancer incidence ratios in the affected and neighboring regions were calculated based on the central cancer registry. Households in the region were sampled using the random stratified sampling technique, and questionnaires were administered to family members, via home visit and via students in elementary to high schools. Information on duration of residency and frequency of use of the roads was applied to calculate cumulative radiation exposure dose from the roads, alongside with the reported 137 Cs contamination amounts. Information on past medical history, perceived risk, anxiety and psychological stress was also obtained. Of the 31,053 residents, 8,875 were analyzed. To examine possible associations between radiation exposure and health problems, logistic regression adjusted for covariates were performed with consideration of the sampling design, population weight and stratification. Results: No significant association was found between self-informed diseases, including cancers, and estimated radiation exposure dose. According to an increase of radiation level, a significant increase in anxiety in all and a decline in the psychosocial wellbeing of the adults was noted. The risk perception level was higher in the elderly, females, the less educated, and the highest exposed individuals. Conclusion: This study provides a basis for risk communication with residents and community environmental health policy.

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