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진행성 간문부담관암 환자에서 내시경 담도배액술 단독 치료와 경피경간 담도배액술을 병행한 담도경하 광역동치료의 생존율의 비교 연구
천영국 ( Young Koog Cheon ),조영덕 ( Young Deok Cho ),백승훈 ( Seung Hoon Baek ),차상우 ( Sang Woo Cha ),문종호 ( Jong Ho Moon ),김연수 ( Yun Soo Kim ),이준성 ( Jun Seong Lee ),이문성 ( Moon Sung Lee ),심찬섭 ( Chan Sup Shim ) 대한소화기학회 2004 대한소화기학회지 Vol.44 No.5
Background/Aims: Photodynamic therapy (PDT) has a promising effect on non-resectable hilar cholangiocarcinoma. The aim of this study was to compare overall survival of PDT plus biliary drainage versus biliary stent alone in advanced hilar cholangiocarcino
천강민(Kang-Min Cheon),장종호(Jong-Ho Jang),허장욱(Jang-Wook Hur) 한국기계가공학회 2021 한국기계가공학회지 Vol.20 No.10
An analysis was conducted to predict the behavior of gasket by applying an optimal-strain energy-density function selected through a uniaxial tensile test and an analysis of the gasket used in an actual hydrogen fuel cell. Among the models compared to predict the materials" properties, the Mooney-Rivlin secondary model showed the behavior most similar to the test results. The maximum stress of the gasket was not significantly different, depending on the location. The maximum surface pressure of the gasket was higher at positions “T” and “Y” than at other positions, owing to the branch-shape effect. In the future, a jig that can measure the surface pressure will be manufactured and a comparative verification study will be conducted between the test results and the analysis results.
알코올 의존 환자에서 Mirtazapine과 SSRI의 효과에 관한 전향적 비교 연구
천영일(Young- Il Cheon),이태경(Tae- Kyung Lee),이종일(Jong- Il Lee) 한국중독정신의학회 2004 중독정신의학 Vol.8 No.2
Objectives:There have been growing concerns about the pharmacological treatment of alcohol dependence. Serotonergic medications, particularly the selective serotonin reuptake inhibitors (SSRIs), have been extensively evaluated for the treatment of alcoholism. Of serotonergic agents, especially the effect of ondansetron, a 5-hydroxytryptamine-3 (5-HT3) antagonist, has also been studied. However mirtazapine, noradrenergic and specific serotonin 5-HT2 and 5-HT3 antagonist, have not yet been investigated. This study was performed to compare the efficacy of mirtazapine versus SSRIs in the treatment of alcohol dependence. Methods:The subjects were 46 inpatients with alcohol dependence. They were admitted to the Alcohol & Drug Addiction Center in Seoul National Hospital. They were randomly assigned into one of the two groups:mirtazapine group (n=20) or SSRIs group (n=26). All subjects received the psychosocial treatment program for alcoholism. All of the subjects were assessed by scales:The Korean version of Alcohol Use Disorders Identification Test (AUDIT-K), Obsessive Compulsive Drinking Scale (OCDS), Beck Depression Inventory (BDI), Aggression Questionnaire (AQ), and Three-dimensional Personality Questionnaire (TPQ) at baseline and 8 weeks later. Results:There were no differences between mirtazapine group and SSRIs group in baseline BDI, AUDIT-K, OCDS, AQ, TPQ scores and demographic characteristics. After 8-week treatment period, BDI, AUDIT-K and OCDS scores decreased significantly in total subjects. Mirtazapine group had a greater reduction of the BDI scores than SSRIs group at week 8. The aggression scores did not decrease significantly during treatment;the difference between the two groups was not significant. There was no significant change on TPQ. Conclusion:Both mirtazapine and SSRIs are effective to comorbid depressive symptoms and compulsive drinking of alcohol dependence. Moreover mirtazapine is resulted to be more effective in treating depressive symptoms of alcohol-dependent patients. Consequently, our results provide evidences that mirtazapine may be an effective pharmacological treatment for alcohol dependence with comorbid depression and compulsive drinking.
환경온도가 비육돈의 호흡수, 직장 온도 및 체표면 온도에 미치는 영향
천시내(Si-Nae Cheon),박규현(Kyu-Hyun Park),최희철(Hee-Chul Choi),김종복(Jong-bok Kim),권경석(Kyeong-Seok Kwon),이준엽(Jun-Yeob Lee),우샘이(Saem-Ee Woo),양가영(Ga-Yeong Yang),전중환(Jung-Hwan Jeon) 한국산학기술학회 2019 한국산학기술학회논문지 Vol.20 No.1
최근 우리나라도 지구온난화와 기후 변화의 영향으로 여름이 길어지고 기온이 상승하는 등 이상기후 현상에 의한 피해가 속출하고 있으며 특히, 축산 분야에서 환경온도는 가축의 생산성과 직접적인 연관이 있으므로 매우중요하다. 본 연구는 열 환경에 관한 가축 사양관리 자료를 확보하기 위해 환경온도에 따른 돼지의 호흡수, 피부 및 직장온도의 변화를 조사하였다. 비육돈[(Landrace x Yorkshire) x Duroc, 98.3 ± 6.6kg] 4두를 공시하였으며, 완전 밀폐되어 있는 온습도제어실(Chamber) 내부에 대사틀(150 x 48 x 109 cm)을 설치하여 실험을 실시하였다. 비육돈은 3일간 (25.2 ± 2.4℃, 83.0 ± 5.9%)의 적응 기간을 가진 다음, 동일한 상대습도(68.4 ± 5.9%) 내에서 환경온도(22℃, 24℃, 26℃, 28℃, 30℃)를 구분하여 이틀씩 노출시켰으며, 이 때 별도의 휴식시간 제공 없이 총 10일간 연속적으로 실험을 실시하였다. 사료섭취량(kg/day), 음수량(ℓ/day), 호흡수(breaths/min), 직장온도(℃) 및 체표면 온도(℃)를 하루 2회 측정하였으며, 체표면 온도는 머리, 귀, 목, 등, 옆구리 등 5부위를 측정하여 기록하였다. 실험결과, 호흡수는 26℃구간에서 분당 52.83 ± 15.7회로 증가하기 시작하였고, 30℃구간에서는 71.25 ± 18.3회로 22℃와 24℃구간에 비하여 약 2배 증가하였다(p<0.05). 체표면 온도는 환경온도에 더욱 민감하게 반응하는 것으로 나타났는데 환경온도 30℃구간에서는 측정부위별 온도가 모두 5~7℃씩 증가하였다. 특히 귀와 옆구리 부위의 체표면 온도가 각각 39.84 ± 1.1℃, 39.33 ± 1.0℃로 다른 3부위(머리, 목, 등)의 체표면 온도에 비하여 높게 나타났다. 반면, 직장온도와 사료 섭취량 및 음수량에서는 유의적인 차이가 없었다. Recently, Korea has been affected by extreme weather events including extended summers and increased temperatures caused by global warming and climate change. Environmental temperature is especially important to the livestock industry because it is closely related to livestock productivity. This study was conducted to investigate the influence of different environmental temperatures on respiration rate, rectal temperature and body-surface temperature in finishing pigs. Pigs (98.3 ± 6.6kg) were housed in individual cages inside an experimental chamber and exposed continuously to one of five environmental treatments (22°C, 24°C, 26°C, 28°C, 30°C) for 10 days without providing additional rest time. Feed and water intake, respiration rate, rectal temperature and body-surface (head, ear, neck, back, side) temperature were measured two times daily during the experimental period. A significant increase in respiration rate from 26°C and in body-surface temperature from 24°C (p<0.05) was observed. At 30°C, the respiration rate had almost doubled and the body-surface temperature increased by about 5°C-7°C. Moreover, ear skin temperature was very sensitive to environmental temperature. However, feed intake, water intake and rectal temperature did not change significantly during the experiment.
Basic study on hysteresis modeling using micromagnetics for magnetic field analysis
천영진(Cheon Yeong Jin),김종태(Kim Jong Tae),위상봉(Wee Sang Bong) 대한전기학회 2007 대한전기학회 학술대회 논문집 Vol.2007 No.11
In magnetic field analysis of electrical machines, hysteresis phenomena of B-H curves should be taken into account in order to obtain more accurate results. In this paper, the hysteresis modeling using the micromagnetics for the magnetic field analysis is investigated. In the micromagnetics, usually, it takes much CPU times. Therefore, the method for representing hysteresis phenomena by minimum modeling is investigated in order to applying it to the magnetic field analysis. First, the micromagnetics is described. Then, the method of minimum modeling is shown. Finally, the hysteresis curve obtained by the minimum modeling is demonstrated. The effect of parameters of micromagnetics on the shape of hysteresis curve is investigated.