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      • KCI등재

        Protective Effects of Extract with Phenolics from Camellia (Camellia japonica) Leaf against Oxidative Stress-induced Neurotoxicity

        정창호,Ji Hye Kim,Gwi Nam Choi,Ji Hyun Kwak,김대옥,허호진 한국식품과학회 2010 Food Science and Biotechnology Vol.19 No.5

        Antioxidant and neuronal cell protective effects of aqueous extract from camellia (Camellia japonica) leaf (CJLE) were evaluated. The 1,1-phenyl-2-picrylhydrazyl (DPPH) radical scavenging and ferric reducing/antioxidant power (FRAP) assays of the CJLE were increased in a dose dependent manner. In neuronal cell viability assay using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazoliumbromide (MTT), the aqueous extract showed protective effect against H2O2-induced neurotoxicity and lactate dehydrogenase (LDH) release into medium was also inhibited by CJLE (7.13-43.89%). The cell viability of CJLE was higher than vitamin C (200 μM) by neutral red uptake (NRU) assay at a concentration of 250-1,000 μg/mL. Phenolics of CJLE were 21.75mg/g, and major phenolic compounds were quercetin (120.20mg/100 g) and kaempferol (88.13 mg/100 g). Therefore these data suggested that the CJLE including above phenolics may be useful in the natural antioxidant substance and reduce the risk of neurodegenerative disease such as Alzheimer's disease.

      • KCI등재

        정보화마을 공동체 형성에 관한 연구

        정창호(鄭彰鎬),박치성(朴致成) 한국지역정보화학회 2014 한국지역정보화학회지 Vol.17 No.3

        이 글은 정보화마을 간 상호연계구조의 패턴을 분석하고 정보화마을 공동체가 어떻게 구성되어 있는지를 파악하는 탐색적 연구이다. 구체적으로 광역자치단체 수준과 전국 수준으로 나누어 정보화마을 간 자매결연을 중심으로 상호협력 네트워크의 특성 및 패턴을 분석하였다. 분석결과 첫째, 광역자치단체 수준에서는 네트워크 연결이 잘 되어있는 4개 광역단체와 네트워크 구조가 파편화되어 있는 5개 광역단체로 구조적 특성이 파악되었다. 둘째, 전국수준에서는 안전행정부 정보화마을이 네트워크 연결에 있어 중요한 역할을 하고 있으며, 주로 같은 지역 내 가까운 마을 간 협력 네트워크 구축이 활성화되고 있는 특성이 발견되었고, 4개의 광역단체에서 5개의 정보화마을이 전체 네트워크의 연결에 있어 중요한 다리역할을 하고 있는 것을 발견하였다. 이러한 분석결과를 바탕으로 향후 정부가 정보화마을 간 공동체 네트워크를 활성화하기 위해서는 마을 간 전략적 연계 및 고립되어 있는 정보화마을들이 공동체 네트워크에 자연스럽게 편입될 수 있는 정책적 지원이 필요하다. This study aims to explore inter-village linkage patterns of Information Network Villages Communities both at the metropolitan and national level through social network analysis. Using sisterhood relations which indicate collaborative relationships among villages, this study examined structural properties of Information Network Villages Community. Main findings are; 1) two types of network structures were discovered among nine metropolitan level village communities, and 2) at the national level, the central government is still playing a significant role in terms of network connectedness in the Information Network Villages Communities Network. In addition, couple of Information Network Villages plays a connecting role between various other Information Network Villages. On the basis of analysis results, this study suggested policy implications to improve the Information Network Villages Communities.

      • 차체 레이저 원격용접에 관한 연구

        정창호,장인성,이희범 한국자동차공학회 2006 한국자동차공학회 Workshop Vol.2006 No.-

        Nowadays, most automotives companies are making use of laser welding in car body assembly shop. But even though laser welding is better than resistance spot welding in many points, its application has been limited to special technology for manufacturing. The paper introduces in the field of remote welding system(RWS) to improve the process efficiency of laser welding. Positioning time of RWS between welding stitches are dramatically reduced to zero. It is a kind of solutions to generalize laser welding in mass production. This RWS consists of fiber laser, industrial robot and 3-axis scanner head or CO₂ laser, fixed beam guide and 3-axis axis scanner head.

      • KCI등재

        적색 및 녹색 풋고추의 화학성분

        정창호,심기환 경상대학교 농업생명과학연구원 2001 농업생명과학연구 Vol.35 No.-

        품종에 따른 전통 향신료로서 이용가치를 결정하고 한국인의 식습관에 맞는 고추의 품질을 개선하기 위하여 적색 및 녹색 풋고추의 화학성분을 비교, 분석한 결과 일반성분은 적색 풋고추와 녹색 풋고추에서 총당이 각각 6.87%와 4.63%로 나타났으며, 무기성분은 K 및 P이 적색 풋고추와 녹색 풋고추에서 370.12 ㎎%, 162.28 ㎎% 및 44.36 ㎎%, 38.80 ㎎%로 각각 높게 나타났고, 비타민 C는 적색 풋고추에서는 169.77 ㎎%, 녹색 풋고추에서는 72.45 ㎎%로 각각 나타났다. 유리당 함량은 적색 풋고추와 녹색 풋고추에서 fructose(1,852.0 ㎎%, 216.4 ㎎%)와 galactose(1,443.7 ㎎%, 292.2 ㎎%)가 높게 나타났으며, 유기산의 경우 적색 풋고추에서는 citric acid가 672.40 ㎎%, 녹색 풋고추에서는 succinic acid가 311.49 ㎎%로 높게 나타났다. 지방산 조성은 적색 풋고추와 녹색 풋고추에서 linoleic acid가 각각 32.89%와 36.20%로 높게 나타났으며, 아미노산 함량은 적색 풋고추에서는 aspartic acid가 237.4 ㎎%로 높게 나타났고, 녹색 풋고추에서는 glutamic acid가 237.2 ㎎%로 가장 높게 나타났다. 색도는 녹색 풋고추는 적색 풋고추에 비해 L값은 높았으나 a, b값은 낮게 나타났다. To study the availability of the Capsicum annuum. L as traditional herbs and in order to improve quality, the properties of chemical components were investigated. Among general components of unripe red and green pepper, total sugars portions from unripe red and green pepper took 6.87% and 4.63%, respectively. The mineral component contents of the unripe red and green pepper were K(370.12 ㎎%, 162.28 ㎎%) and P44.36 ㎎%, 38.80 ㎎%), respectively. The contents of vitamin C was 169.77 ㎎% for unripe red pepper and 72.45 ㎎% for unripe green pepper and that of free sugar was 1,852.0 ㎎% of fructose for unripe red pepper and 292.2 ㎎% of galactose for unripe green pepper and that of organic acid was 672.40 ㎎% of citric acid for unripe red pepper and 311.49 ㎎% of succinic acid for unripe green pepper. The highest fatty acids in unripe red and green pepper was linoleic acid and its composition was 32.89% and 36.20%, respectively. The highest component of total amino acids in unripe red and green pepper was aspartic acid(237.4 ㎎%) and glutamic acid(237.0 ㎎%), respectively. Unripe red pepper showed higher Hunter parameter a and b value and lower L value than unripe green pepper.

      • 원발성 여성 요도 종양의 임상특성 및 추적관찰

        정창호,류현열 고신대학교 의학부 2004 高神大學校 醫學部 論文集 Vol.19 No.1

        Background : Female urethral lesions encompass a spectrum of entities that have significance in clinical urology. With that, female urethral lesions have rarely been reported and the differential diagnosis between benign and malignant lesions has not been established. I investigate retrospectively the incidence and the clinical presentations of female urethral lesions by my experience about 20 cases of the female primary urethral tumor. I also analyze the data to determine the optimum procedure for diagnosis and therapy. Method : The study included 20 patients with female urethral tumor treated by surgical procedure at Masan Samsung hospital of Sungkyunkwan University between Jan. 1994 to Apr. 2001. We investigated the clinical aspect of the female urethral tumor by symptom of each lesion, the spread of the patient's age, the method of the diagnosis and treatment. The preoperative evaluation included a thorough clinical history, physical examination, urinalysis, urine cytology, cystourethroscopy, and the radiologic studies, including voiding cystourethrography, retrograde urethrography, pelvic ultrasonography, pelvic CT or MRI. Results : The age range of the patients, who were surveyed for the 20 cases of the primary tumor, was between 25.2 and 74.6 (mean age 46.9 years), and 8 of them were in the period of menopause. We can inspect urethral diverticulum and we can treated it through diverticulectomy only. 4 cases were necessary to use Martius interposition graft when the path between urethra and the diverticulum was large. 2 cases had the stress incontinence postoperatively and there were necessary anterior vaginal wall sling procedure. The tumor was removed under transvaginal approach in urethral leiomyoma and leiomysarcoma and had not seen a significant morbidity. Urethral transitional cell carcinoma was found that it metastasized to the inguinal lymph nodes and distant metastasis to lung and bone after radical total cystourethrectomy. After the surgical excision of the benign urethral lesions, there would be no relapse or progression to malignancy. Conclusion : Urethral masses are essentially needed radiologic or endourologic procedure and pathologic examination due to possible development of a malignant tumor even though it is rare. A large scale of the urethral tumor like the leiomyoma of urethral diverticulum could be cured and safely managed by surgical excision, but the preventive procedure of the stress incontinence was needed. Finally it is important to perform auxiliary radiotherapy or chemotherapy with radical cystourethrectomy in female urethral malignant tumor to prevent the disease progression.

      • KCI등재후보

        지방 소도읍 지역 생활환경 분석에 관한 연구 -하동 시장을 중심으로-

        정창호,이태곤,안재락 건국대학교 부동산도시연구원 2016 부동산 도시연구 Vol.8 No.2

        Eup in South Korea has been functioning as an economic, social and cultural-center of a local town. But the industrialization and the development of modern transportation system had led to the gradual deterioration of this small town. It had impacted on the role of traditional market which is usually located in the center of Eup. The purpose of this study is to find the possible means to restructure the function of the traditional markets located in the center of Ha-dong eup. To investigate it, we analyzed the deterioration phenomenon of eup, the current status of traditional markets, and outcome of the revitalization policies. Traditional markets face the issues of the functional deterioration and inefficient space use. Eup still takes up for a large area of city center and it speeds up the deterioration of small towns and town center. Therefore, it is required to change the perspective of traditional market. Rather than commercial space, it should be regarded as a public space with community centric function. The government policies for revitalization should focus more on enhancing the culture, living environment, welfare, tourism, and service functions. 본 연구는 군단위의 중심시가지인 읍의 쇠퇴현황과 육성정책, 특히 전통시장에 대한 지원 실태를 분석하고, 해당지역을 비교적 잘 알고 있는 공무원을 대상으로 하는 전문가 설문조사와 읍의 중심 시가지이자 전통시장인 하동시장 주변의 통행량 조사를 통해 지방소도시의 중심지인 읍에서의 생활패턴과 지역에 대한 인식을 분석하고자 하였다. 연구대상지는 경남의 군지역에서 가장 규모가 작아 중심성이 약한 지역인 하동읍을 선정하였다.

      • KCI등재

        기계식 제동 방식을 갖는 에스컬레이터의 과속역행 방지장치 성능평가

        정창호,의창,조종두 대한기계학회 2022 大韓機械學會論文集A Vol.46 No.11

        In this study, a mechanical brake (also known as a reverse-driving prevention device) is installed in an escalator to prevent, reduce, and mitigate escalator overspeed or reverse-driving accidents. Because it is a safety device that requires excellent braking performance and structural integrity, evaluating the strength and safety of parts is necessary to ensure the reliability of the device. However, due to the unique characteristics of the device, measuring the stress of major parts is difficult. In this study, the structural safety of the mechanical brake when the escalator overspeeds or a reverse-driving event occurs is verified using a finite element method. The study showed that the maximum stress generated in the entire system under braking conditions was 37.3 MPa and that the minimum safety factor was 3.8, confirming the structural safety of the system. 과속역행 방지장치는 에스컬레이터에서 발생할 수 있는 과속 혹은 역주행 사고에 대한 예방·감소·완화의 목적으로 설치되는 장치다. 해당 장치는 안전을 목적으로 설치되는 장비이며 뛰어난 제동성능과 구조안전성이 요구되므로, 제품의 신뢰성 확보를 위한 부품의 강도 및 안전성 평가가 반드시 필요하다. 그러나 과속역행 방지장치의 특성상 다양한 구조요소가 결합되므로 신뢰성 평가를 위하여 주요부위에서 응력을 측정하는 것은 쉽지 않다. 본 연구에서는 유한요소 해석을 활용하여 에스컬레이터의 과속 혹은 역주행 상황 발생 시 과속역행 방지장치의 구조안전성 평가를 수행한다. 주요연구 결과로 과속 및 역주행 제동 상황 시 전체 시스템에서 발생한 최대응력은 37.3 MPa, 최저 안전율은 3.8로 해당 시스템의 구조적 안전성을 확인하였다.

      • KCI등재

        진공창호시스템 부위별 표면온도 분포 및 결로 발생 특성에 관한 실험연구

        정창호(Jeong, Chang-Ho),박재성(Park, Jae-Sung),여명석(Yeo, Myoung-Souk),김광우(Kim, Kwang-Woo) 대한건축학회 2013 대한건축학회논문집 Vol.29 No.10

        In this study, characteristics of the surface temperature and condensation on a window were assessed, using vacuum insulated glass units produced by the in-vacuum chamber method. For this purpose, mock-up test was performed, based on the result of preliminary study about the test methods of the surface condensation resistance performance of a window system. A general double glass window(DG Window) was selected as an alternative for comparison. As a result, in the same location, the surface temperature of the vacuum insulated glass window(VIG Window) was 4~6 ℃ higher, in comparison with a general DG window. The surface temperature on the center of glass in the VIG window was higher than that on the frame, because of the thermal performance of the vacuum insulated glass(VIG). On the other hand, the surface temperature on the edge of glass in the VIG window was still lower (0.9~1.5℃), than that on the frame. Therefore, for improvement of the surface temperature distribution in a VIG window, a strategy to reduce heat loss in the glass-intersection, as well as the application of a frame with equal or greater thermal performance, in comparison with the vacuum insulated glass, are required. Under the condition of room air temperature 20℃ and relative humidity of 50%, the calculated outdoor air temperature was .21.2℃, when indoor surface condensation on the VIG window begins to occur. Analyzing based on the standard weather data for Seoul, it was expected that surface condensation on the VIG window would not occur.

      • KCI등재

        시판 비파나무잎차의 영양성분 및 항산화 활성

        정창호,김일훈,심기환,배영일 경상대학교 농업생명과학연구원 2011 농업생명과학연구 Vol.45 No.4

        본 연구에서는 시판 비파나무잎차의 영양성분 분석 및 열수 추출물을 이용하여 항산화 효과를 조사하였다. 일반성분은 수분 5.34%, 조단백 8.38%, 조지방 13.26%, 가용성 무질소물 46.21%, 조섬유 19.24% 및 조회분 7.57%순으로 함유하고 있었다. 비타민 C 함량과 총페놀 함량은 각각 0.47 mg/100 g 및 42.55 mg/g이였다. 무기성분은 Ca, K 및 Mg 순으로 높게 나타났으며, 그 함량은 각각 1,624.01, 1,099.66 및 192.70 mg/100g이었다. 비파나무잎차의 아미노산 분석 결과 glutamic acid (565.98 mg/100 g)가 가장 높게 함유되었고, 반면 가장 낮은 함량은 cystine (12.97 mg/100 g)이였다. 시판 비파나무잎차 열수 추출물 농도 1,000 μg/mL를 기준으로 했을 때 각각 86.87%와 98.14%의 ABTS 및 DPPH 라디칼 소거활성을 보였으며, 환원력과 ferric reducing antioxidant power (FRAP)는 농도 의존적 항산화 활성을 보였다. 따라서 시판 비파나무잎차는 항산화제와 같은 기능성 식품 소재로 이용가능성이 높을 것으로 생각된다. Nutritional components and antioxidant activities of commercial loquat leaf tea (CLLT) were evaluated. Proximate compositions were as follows; moisture 5.34%, crude protein 8.38%, crude fat 13.26%, nitrogen free extract 46.21%, crude fiber 19.24% and crude ash 7.57%, respectively. Ascorbic acid and total phenolics content of CLLT was 0.47 mg/100 g and 42.55 mg/GAE g, respectively. Mineral elements were Ca 1,624.01 mg/100 g, K 1,099.66 mg/100 g, and Mg 192.70 mg/100 g, respectively. Amino acid contents of CLLT were very rich in glutamic acid 565.98 mg/100 g and deficient in cystine 12.97 mg/100 g. The 2,2'-azino-bis (3-ethylbenzthiazoline-6- sulfonic acid) diammonium salt (ABTS), 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activities of hot water extract from CLLT were 72.51% and 90.11%, respectively at a concentration of 1,000 μg/mL. Reducing power and ferric reducing antioxidant power (FRAP) of hot water extract from CLLT were increased in a dose dependent manner. Therefore, these results suggest that the hot water extract of CLLT possess antioxidant activities and thus it has great potential as a source for functional food such as natural antioxidant.

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