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      • KCI등재

        Understanding the Transport Mechanism of Paleo-deposits in the Sonoran Desert with Grain Size Distribution and Shape Analysis

        정아라 한국지리학회 2020 한국지리학회지 Vol.9 No.2

        About tens of meters thick fine sand and silt deposits are observed at the top of the sedimentary logs of hundreds of drilling wells throughout Phoenix metropolitan area, Arizona, USA, situated in north-central Sonoran Desert, and likely deposited after ~ 836ka. A hypothesis to explain the paleo-deposits is that the deposits are a wind-blown deposits derived from the floodplains of nearby rivers developed in response to the aeolian-fluvial interactions. The purpose of this study is to reconstruct paleoenvironment and to understand the processes of transport and deposition of the paleo-deposits using modern analogues. This is accomplished via the identification of the paleo-deposits by comparison with modern source-bordering dune sediments and fluvial sediments using the analyses of grain size distribution and grain shape parameters. Overall, the results of sediment drift potential, grain size distribution and shape analyses provide evidence to support the hypothesis, and the deposition of the paleo-deposits may be related with the change of regional climates. Grain shape parameters may better reflect the mechanism of transport when grains traveled over short distance. Given the advantage, the grain shape analysis may provide a new insight to solve the issue associated with the provenance of Korean loess-like sediments whether it was originated from far-distant the Chinese Loess Plateau and peripheral areas or from nearby floodplains of local river or from exposed fine materials in the Yellow Sea.

      • The effect of plasma surface treatment on osseointegration of dental implant

        정아라,김서영,전현정,임도형,임유봉,권보미 대한기계학회 2021 대한기계학회 춘추학술대회 Vol.2021 No.4

        According to recent reports, surface wettability is known to impact on osseointegration of implants. It was shown that adhesion of osteoblast can be improved by modifying the surface to be hydrophilic. To increase the hydrophilicity, we utilized a cylindrical type capacitively coupled plasma (CCP) designed to fit the dental implant shape. Our CCP source was operated under a moderate vacuum condition of 3 torr for stable and uniform plasma discharge. To investigate the efficiency of osseointegration following plasma treatment, we evaluated protein adsorption, cell adhesion, and differentiation on plasma treated dental implants. Two types of dental implants were used to compare the osseointegration efficiency, namely, sandblasted and acid-etched (SLA) type and calcium-coated type were used. Protein adsorption assay showed that protein adhere more by plasma treatment in both implant types. Also, cell adhesion assay showed that plasma treatment enhanced cell adhesion and proliferation. In conclusion, plasma treatment seems to be advantageous for osseointegration on dental implant surfaces.

      • KCI등재

        북아메리카 사막 지형에 미친 인류의 영향: 피닉스, 애리조나 지역을 사례로

        정아라 한국지형학회 2019 한국지형학회지 Vol.26 No.3

        Humans have been important driver to reconfigure the terrestrial surface of the Earth by altering its morphology and processes. The effect of human activities on the physical landscape, however, shows substantially uneven geographical patterns. Most of anthrogemorphoogical studies regarding human-induced denudation have focused on areas with a long history of human modifications such as humid landscapes, so the hypothesis is naturally a great human impact on landscapes. The effect of human activities on dryland Earth surfaces are far less commonly studied, although erosion is one of major concerns in arid and semiarid region regarding land and water quality degradation. The urban metropolis of Phoenix, Arizona, USA provides an opportunity to explore the impact of the Anthropocene. The Phoenix metropolitan area rests on classic desert landforms, such as extensive pediments, alluvial fans and sand sheets. Human activities including cattle crazing, wildfire resulting from introduced grass species by human, and recent urbanization processes have impacted these classic desert landforms and altered geomorphic processes. The purpose of this paper, therefore, rests in examining Anthropocene in the geomorphology of the north-central Sonoran Desert. The objectives of this paper are: i) to understand the impact of the Anthropocene on the geomorphological processes and forms through field observations; ii) to quantify the magnitude of human impacts on landscape using a published two-decade long record of erosion dataset and natural background erosion dataset in submitted manuscript at the sprawling edge of the Phoenix metropolitan region; iii) to examine how geomorphic outcome can affect the sustainability of cities through the estimation of sediment yield under the condition of urban sprawl.

      • KCI등재

        Genetic Analysis of Locally Advanced Well-Differentiated Thyroid Cancer: Clinical Prognostic Implications

        정아라,강순성,전승연,이윤세 대한이비인후과학회 2023 대한이비인후과학회지 두경부외과학 Vol.66 No.12

        Background and Objectives Despite the usually favorable prognosis of well-differentiatedthyroid cancer (WDTC) following appropriate treatment, advanced T-staged WDTCs are as-sociated with poor prognosis. This study focused on identifying genes associated with theprognosis of locally advanced WDTC by analyzing a The Cancer Genome Atlas cohort. Subjects and Method We analyzed the data of 501 patients with WDTC and classifiedthem into two subgroups: pathological T4 stage (Cluster 1) or T1-3 stage (Cluster 2). We com-pared the mRNA expressions of thyroid cancer-related genes, and the somatic mutation fre-quencies of various cancer genes between the two subgroups. Results Cluster 1 included 23 patients (papillary=21/follicular-variant papillary thyroid can-cer [FVPTC]=2) and Cluster 2 478 patients (papillary=371/ FV PTC=10 0/ot her s=7). Cluster 1showed worse overall and disease-free survival than Cluster 2 ( p<0.05 and p=0.12 , respe c-tively). Patients with pT4 stage had about a 1.8-fold increased risk of overall recurrence ordeath. MET, SERPINA1, TIMP1, PROS1, FN1, CDKN2A, and CDKN2B were significantly ele-vated while TG, DNAH9, TFF3, CR A BP1, TPO, JAK2, KIT, KDR, and NFE2L2 were signifi-cantly lower in Cluster 1 (all, p<0.05 and adjusted p<0.05). A TERT, EIF1A X, and ATMshowed significantly frequent somatic mutations in Cluster 1 when compared to Cluster 2. Wealso identified seven pathways related to 16 genetic markers. Conclusion Locally advanced WDTC presented 16 genetic alterations. We identified so-matic mutations associated with local invasion transformation. Relevant pathways related tothe 16 genetic markers could be therapeutic targets. Genetic analysis of locally advancedWDTC may be used to predict clinical applications in patient survival.

      • KCI등재

        A Case of Inflammatory Pseudotumor Cerebri and Nasal Septum

        정아라,하영민,강정욱,이건희 대한이비인후과학회 2017 대한이비인후과학회지 두경부외과학 Vol.60 No.2

        Inflammatory pseudotumors, which clinically mimic neoplasms, are space-occupying collections of inflammatory cells, histiocytes, and fibroblasts. They are most often found in the orbits and lungs, but rarely in the head and neck region, and hardly ever in the nasal septum. Here we report on a 71-year-old woman with pseudotumor cerebri and an inflammatory pseudotumor of the nasal septum. This case demonstrates that inflammatory pseudotumor can cooccur in the brain and nasal septum. Korean J Otorhinolaryngol-Head Neck Surg 2017;60(2):83-6

      • SCOPUSKCI등재
      • KCI등재

        골프콘텐츠를 활용한 유튜브의 지각된 상호작용성이 사회적실재감 및 지속시청의도에 미치는 영향

        정아 한국골프학회 2020 골프연구 Vol.14 No.4

        [목적] 이 연구는 골프 마케팅 차원에서 골프 콘텐츠를 활용한 유튜브를 중심으로 가장 중요한 매커니즘인 상호작용 성이 사회적 실재감과 지속시청의도에 어떠한 영향을 미치는지 규명하는데 연구의 목적이 있다. [방법] 편의표본추 출법을 통해 골프관련 유튜브를 시청한 경험이 있는 225명에게 설문조사를 실시하였다. 수집된 자료는 빈도분석, 타 당도, 신뢰도 분석, 기술통계 분석, 상관관계 및 구조방정식 모형을 검증하였다. [결과] 첫째 골프 유튜브의 상호작용 성은 사회적 실재감에 긍정적인 영향을 미치는 것으로 나타났다. 둘째, 골프 유튜브의 사회적 실재감은 지속시청의 도에 긍정적인 영향을 미치는 것으로 나타났다. 셋째, 골프 유튜브의 상호작용성은 지속시청의도에 부분적으로 긍정 적 영향을 미치는 것으로 나타났다. [결론] 골프 유튜버의 상호작용성은 사회적 실재감을 형성하며 이는 지속시청의 도에 긍정적 영향을 미친다. 반면 사회적 상호작용성은 지속시청의도에 영향을 미치지 않는 것으로 나타났다. [Purpose] The purpose of this study is to find out how interaction with YouTube using golf content affects the sense of social reality and the willingness of continuous Viewing Intention [Method] The survey was conducted on 225 people who had watched Youtube of Golf contents sampling method. Then, frequency analysis, reliability analysis, confirmatory factor analysis, descriptive statistics analysis,correlation analysis, and structural equation model [Result] First, YouTube's interaction with golf content has a positive impact on social reality. Second, YouTube's sense of social reality using golf content has a positive impact on its sustainability. Third, the interactivity of YouTube using golf content has been shown to have a positive effect on the degree of continuous viewing. [Conclusion] Golf YouTubers' interactivity creates a sense of social reality, which has a positive effect on their sustainability. Social interaction, on the other hand, was found to have no effect on the willingness to continue.

      • KCI등재

        골프초보자의 골프용품 구매결정요인이 구매만족과 구매 후 행동에 미치는 영향

        정아,서일한,김선희 한국골프학회 2020 골프연구 Vol.14 No.3

        [목적] 본 연구에서는 골프초보자의 골프용품 구매결정요인이 구매만족과 구매 후 행동 간의 관계를 규명하는데 그 목적이 있다. [방법] 설문은 총 240부의 설문지를 배부하여 236부를 회수하였고, 11부의 결측된 자료를 제외한 225부 를 바탕으로 연구를 진행하였다. 자료처리는 SPSS 25.0을 사용하였으며, 본 연구의 결과는 다음과 같다. [결과] 첫째, 골프초보자의 골프용품 구매결정요인이 구매만족에 미치는 영향을 분석한 결과 구매결정요인의 하위요인 중 가격, 품질, 디자인, 브랜드는 구매만족에 정(+)의 영향을 미치는 것으로 나타났다. 둘째, 골프초보자의 골프용품 구매결정 요인의 하위요인 중 가격, 디자인, 브랜드는 구매 후 행동에 정(+)의 영향을 미치는 것으로 나타났다. 셋째, 골프초보 자의 골프용품 구매만족이 구매 후 행동에 정(+)의 영향을 미치는 것으로 나타났다. [결론] 따라서 연령과 직업면에 서도 계층이 다양해진 골프초보자의 구매결정요인은 비교적 다양하며, 이에 보다 폭넓게 국민 스포츠로 자리매김하 기 위해서는 골프초보자들을 대상으로 한 좀 더 세분화되고 새로운 마케팅 전략이 필요하다고 하겠다. [Purpose] The purpose of this study is to examine the relationship between purchase satisfaction and post-purchase behavior of golf beginners' purchasing decision factors. [Method] A total of 240 copies of the questionnaire were distributed and 236 copies were collected, and research was conducted based on 225 copies excluding missing data from 11 copies. SPSS 25.0 was used for data processing, and the results of this study are as follows. [Result] First, as a result of analyzing the effects of golf beginners' purchase decision factors on purchase satisfaction, among the sub-factors of purchase decision factors, price, quality, design, and brand were found to have a positive effect on purchase satisfaction. Second, the price, design, and brand among the sub-factors of the beginner's golf product purchasing decision factor have a positive effect on post-purchase behavior. Third, it was found that golf beginners' satisfaction with purchasing golf goods had a positive effect on their behavior after purchase. [Conclusion] Therefore, it is said that the purchase decision factors of golf beginners who have various classes in terms of age and occupation are relatively diverse. Therefore, in order to become a more widespread national sport, a more detailed and new marketing strategy for golf beginners is needed.

      • SCOPUSKCI등재

        임상연구 : 노인에서 Propofol 마취유도 용량에 따른 Bispectral Index 및 혈역학적 변화

        정아리 ( A Lee Chung ),이귀용 ( Guie Yong Lee ) 대한마취과학회 2006 Korean Journal of Anesthesiology Vol.50 No.4

        Background: Propofol is a good choice for elderly patents because it produces rapid onset and quick recovery with few side effects. Propofol produces dose-dependent cardiovascular depression. This effect is more pronounced in elderly patients during induction and can be minimized by a slow injection. The aim of this study was to determine the appropriate induction dose of propofol using a slower infusion rate for elderly patients to obtain desirable sedation and hypnotic conditions with minimal hemodynamic changes. Methods: Thirty-nine patients aged over 70 years were assigned to receive a propofol infusion of either 1.5 mg/kg (n = 21, Group 1) or 2.0 mg/kg (n = 18, group 2). The infusion rate was 20 mg/kg/hr. The systolic and diastolic pressure, heart rate, BIS and modified observers assessment of the alertness/sedation scale (OAA/S) were measured before the induction (baseline), after the propofol infusion, as well as immediately, 3 and 5 minutes after intubation. Results: The systolic pressure decreased significantly after the propofol infusion in both groups (group 1: 17%, group 2: 25%) but there were no significant differences between them. The BIS values after the propofol infusion and intubation were 67.1 ± 12.6 and 62.3 ± 12.7 in group 1, 49.6 ± 11.1 and 51.7 ± 11.7 in group 2, respectively which showed significant differences between the groups. Conclusions: When 2.0 mg/kg of propofol is administrated to elderly patients, a slower infusion rate is more appropriate for maintaining the desirable sedation and hypnotic conditions and cause no significant hemodynamic changes. (Korean J Anesthesiol 2006; 50: 417~21)

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