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정성화,정진형,임성빈,김정근,소은희,Chung, Sung-Wha,Chung, Chin-Hyung,Lim, Sung-Bin,Kim, Jung-Keun,So, Eun-Hee 대한치주과학회 2000 Journal of Periodontal & Implant Science Vol.30 No.3
Gingivitis and periodontitis are infectious diseases in that microorganisms are the primary extrinsic cause of the diseases. the occurrence of gingivitis has been associated clearly with the presence of microorganisms at the disease site, and the histologic nature of the tissue involved is indicative of an inflammatory response induced by microorganisms. additional evidence for the microbial etiology of periodontal disease is that numerous antimicrobial agents are effective in reducing plaque accumulation and periodontal diseases. the purpose of this article is to analyze the antimicrobial effects of Pulsatilla koreana. Well-dried Pulsatilla koreana purchased from herbs distributor was ground and extracted into methanol(MeOH), ethylacetate(EtoAc), chlorform($CHCl_3$) and Butyl alcohol(BuOH). we have then applied each solution to the bacteria samples(Bacteroides forsythus, Streptococcus mutans, Streptococcus sanguis, Porphylomonas gingivalis, Actinobacillus actinomycetemcomitans, Eikenella corrodens, Prevotella intermedia, Actinomyces viscosus, Prevotella nigrescens , Rothia dentocariosa, Fusobacterium nucleatum, Pseudomonas aeruginosa, Staphylococcus aureus) collected from several organizations. To conduct susceptibility test(Kirby-Bauer method), plate contained each periodontopathic bacteria is spread extracted into methanol(MeOH), ethylacetate(EtoAc), chlorform($CHCl_3$) and Butyl alcohol(BuOH) and to measure the minimum inhibition concentration(MIC) of the bacteria against the solutions to ultimately determine antimicrobial effects of the solutions, insert bacteria sample into $20{\mu\ell}/{m\ell}$, $10{\mu\ell}/{m\ell}$, $5{\mu\ell}/{m\ell}$, $2.5{\mu\ell}/{m\ell}$ of each solution and control group(not contained solution) 1. Solution extracted into methanol did not show clear zone against all bacteria samples. Only P.nigrescens, S. mutans and S. sanguis in solution extracted into ethylacetate, S. mutans and S. anguis in solutions extracted into chlorform and Butyl alcohol showed clear zone against all bacteria samples. Solution extracted into Butyl alcohol showed clear zone against 13 types of bacteria, excluding P. gingivalis. 2. In Solution extracted into methanol, the bacteria samples grew in the highest concentrated plate, showing minimal variation from control group. 3. In Solution extracted into Butyl alcohol, S. aureus, P. intermedia, E. corrodens, A. actinomycetemcomitans, B. forsythus, P. gingivalis et al. showed decreased growth in the highest concentrated plate. P. auruginosa, R. dentocariosa, A. viscosus, P. nigrescens, S. mutans et al. showed decreased growth at MIC $20{\mu\ell}/{m\ell}$ and S. sanguis showed decreased growth at MIC $10{\mu\ell}/{m\ell}$. 4. By analyzing the MIC level through considering the results from Kirby-Bauer method, Solution extracted into methanol did not reveal any antimicrobial effects and Solution extracted into Butyl alcohol showed the highest antimicrobial effects In conclusion, it can be used the extracts of Pulsatilla koreana as wide spectrum antimicrobial agent.
정성화,강대룡,허남욱,김진흠,이순영,정상혁,남정모,Jeong, Seong-Hwa,Kang, Dae-Ryong,Hur, Nam-Wook,Kim, Jin-Heum,Lee, Soon-Young,Jung, Sang-Hyuk,Nam, Chung-Mo 대한예방의학회 2006 예방의학회지 Vol.39 No.4
Objectives: The purposes of this study were to propose a screening schedule for the early detection of breast cancer among Korean women, as based on the statistical model, and to compare the efficacy of the proposed screening schedule with the current recommendations. Methods: The development of the screening schedule for breast cancer closely followed the work of Lee and Zelen (1998). We calculated the age-specific breast cancer incidence rate from the Korea Central Cancer Registry (2003), and then we estimated the scheduling of periodic examinations for the early detection of breast cancer, using mammography, and based on the threshold method. The efficacy of the derived screening schedule was evaluated by the schedule sensitivity. Results: For estimating the screening schedule threshold method, we set the threshold value as the probability of being in the preclinical stage at age 35, the sensitivity of mammography as 0.9 and the mean sojourn time in the preclinical stage as 4 years. This method generated 14 examinations within the age interval [40, 69] of 40.0, 41.3, 42.7, 44.1, 45.4, 46.7, 48.0, 49.3, 51.0, 53.2, 55.3, 57.1, 59.0 and 63.6 years, and the schedule sensitivity was 75.4%. The proposed screening schedule detected 85.2% (74.5/87.4) of the cases that could have been detected by annual screening, but it required only about 48.7% (14.0/30.0) of the total number of examinations. We also examined the threshold screening schedules for a range of sensitivities of mammography and the mean sojourn time in the preclinical stage. Conclusions: The proposed screening schedule for breast cancer with using the threshold method will be helpful to provide guidelines for a public health program for choosing an effective screening schedule for breast cancer among Korean women.
아파트 리모델링 시행에 대한 거주자 의식과 리모델링 사례 연구
정성화,이원영,강순주,Jung Sung-Hwa,Lee Won-Young,Kang Soon-Joo 한국주거학회 2004 한국주거학회 논문집 Vol.15 No.4
This study has examined how residents view the remodeling process of their old apartment and the actual conditions of apartment remodeling case in Yonggang-dong, Mapo-gu, Seoul, in Korea. The questionnaire survey has been conducted to apartment residents in Seoul who want to have their houses remodeled in order to specifically find out how they view remodeling process. Furthermore, interviews have been conducted with persons who were in charge of remodeling operations, and related data have been analyzed by conducting on-the-spot survey on apartment in Yonggang-dong. The major findings were as follows 1. The residents pointed out the biggest problem is the lack of information in the remodeling process. Therefore, education and PR on remodeling to residents should be kept on in order for them to play a key role in remodeling operation. 2. In Yonggang apartment remodeling process several problems have been found such as the difficulty of obtainning unanimous consent from residents, the lack of the active and positive participation of residents and the absent of the drawing. Therefore, to activate remodeling of the apartment complex, it needs not only to induce the residents to participate positively, but also to make a practical adjustment on current special repairing allowance.
이종 탈회 건조골 및 Hydroxyapatite 제재의 골 이식이 성견 치조골 결손부 치유에 미치는 영향에 관한 비교연구
정성화,김종여,이재현,Jung, Sung-Hwa,Kim, Jong-Yeo,Lee, Jae-Hyun 대한치주과학회 1994 Journal of Periodontal & Implant Science Vol.24 No.1
This study was conducted to evaluate the healing potential of hydroxyapatite and demineralized freeze dried bone in 5 dogs. Chronic periodontitis was induced by ligating elastic wire randomized as follows. The group in which only flap operation was performed was used as control. The group in which flap operation using nonresorbable nonporous hydroxyapatite (Orthomatrix)was performed was used as experimental I. The group which flap operation using resorbable porous hydroxyapatite (Biocoral) was performed as experimental II. The group in which flap operation using demineralized freeze-dried bone was performed was used as experimental III. Thereafter dogs serially sacrificed at the 1,2,4 and 8 weeks and the specimens were prepared, and stained with Hematoxilin-Eosin stain for the light microscopic evaluation. The results of the this study were as follows : 1. Control group : progressive inflammatory cell infiltration till 4 weeks and epithelial undergrowth. 2. Group I. : epithelial undergrowth and new bone formed with fibrous margin around HA granule. 3. Group II. : no epithelial undergrowth and direct bone formation at the porous granule 4. Group III. : could not see epithelial undergrowth but obviously new cementum formation.
고속도로 안개 잦은 구간 선정 기준 재정립에 관한 연구
정성화 ( Sung Hwa Jung ),이수범 ( Soo Beom Lee ),박준태 ( Jin Tae Park ),이수일 ( Soo Il Lee ),홍지연 ( Ji Yeon Hong ) 한국안전학회(구 한국산업안전학회) 2011 한국안전학회지 Vol.26 No.2
There is a high potentiality of large traffic accident due to the dense fog when road is developed along the coast or river. The establishment of national level control system against the fog is necessary because the accident due to the creation of fog has a high fatality ratio than other weather conditions. The selection method for the frequent foggy area on highway was suggested to control the fog on the highway effectively because the establishment of the countermeasure against the fog in every range in highway is difficult practically. 44 ranges where the fog control is necessary throughout the year and the 45 ranges where the control is necessary in specific months were selected from the result of application of the weighted value on each visible distance data except the fog with beyond 250 m visible distance which does not affect on the safe driving out of the surveyedjsh fog visible distances. The preferential fog control countermeasure shall be provided to prevent the traffic accident and to reduce the severeness of the accident in case of fog creation for 89 ranges which were selected for frequent foggy area in highway.
3차원 레이더 반사도를 이용한 대류세포 판별과 추적 알고리즘의 개발
정성화(Sung-Hwa Jung),이규원(GyuWon Lee),김형우(Hyung-Woo Kim),국봉재(BongJae Kuk) 한국기상학회 2011 대기 Vol.21 No.3
This paper presents the development of new algorithm for identifying and tracking the convective cells in three dimensional reflectivity fields in Cartesian coordinates. First, the radar volume data in spherical coordinate system has been converted into Cartesian coordinate system by the bilinear interpolation. The three-dimensional convective cell has then been identified as a group of spatially consecutive grid points using reflectivity and volume thresholds. The tracking algorithm utilizes a fuzzy logic with four membership functions and their weights. The four fuzzy parameters of speed, area change ratio, reflectivity change ratio, and axis transformation ratio have been newly defined. In order to make their membership functions, the normalized frequency distributions are calculated using the pairs of manually matched cells in the consecutive radar reflectivity fields. The algorithms have been verified for two convective events in summer season. Results show that the algorithms have properly identified storm cells and tracked the same cells successively. The developed algorithms may provide useful short-term forecasting or nowcasting capability of convective storm cells and provide the statistical characteristics of severe weather.