http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
유전자 전달체로 응용하기위해 Folate와 Poly-L-lysine이 결합된 O-carboxymethyl Chitosan의 제조
정경원 ( Gyeong Won Jung ),박순정 ( Sun Jung Park ),김영민 ( Young Min Kim ),남정표 ( Joung Pyo Nam ),최창용 ( Changyong Choi ),박성철 ( Seong Cheol Park ),나재운 ( Jae Woon Nah ),장미경 ( Mi Kyeong Jang ) 한국키틴키토산학회 2013 한국키틴키토산학회지 Vol.18 No.4
In present study, PLL-OCMCh-PEG-FA (POCPF) was prepared to apply the cell targeting gene delivery carrier. The POCPF copolymer was characterized by 1-proton nuclear magnetic resonance ( 1 H-NMR). The result indicated that POCPF has been successfully synthesized. The particle size of the POCPF was 188 ~ 320nm, which was measured by DLS (Dynamic Light Scattering). In addition, gel retardation assay showed that the POCPF has potential to bind with pDNA. Also, it showed that POCPF can be protected pDNA from DNase. The gene transfection efficiency of the POCPF was evaluated in HCT119 cells. The result showed that transfection efficiency of the POCPF was better than the OCMCh and PLL (Poly-L-lysine) via receptor mediate endocytosis between FA and FA receptor on cancer cell surface. The results demonstrated that POCPF copolymer is good candidate as a gene carrier for gene therapy.
치위생학과 학생들의 성격유형이 학업소진과 수면의 질에 미치는 영향
김가람(Ga-Ram Kim),김남연(Nam-Yeon Kim),서은지(Eun-Ji Seo),이상아(Sang-A Lee),이현정(Hyun-Jung Lee),정경원(Gyeong-Won Jeong),정은지(Eun-Ji Jeong),이병호(Byung-Ho Lee) 한국구강보건과학회 2016 한국구강보건과학회지 Vol.4 No.2
The purpose of this study was to reveal association between personality types on academic burnout and sleep quality. Personality types were composed of extraversion, neuroticism, openness, conscientiousness, and agreeableness. We thought these factors affect to the academic burnout and sleep quality. For this study, 218 dental hygiene students in Busan and Gyeongnam are participated in this study. The data were analyzed with descriptive statistics, t-test, ANOVA, pearson’s correlation coefficients, and stepwise multiple regression analysis with SPSS 21.0 program. In conclusion, we obtained the next results. First, the mean of academic burnout was 2.51 out of 5. In terms of sub-domain, exhaustion (2.95) is the highest, followed by inefficacy (2.36) and cynicism (2.01). Second, the influencing factor in academic burnout were neuroticism (β=.363) and conscientiousness (β=-.263), adjusted R2=.199. Third, the influencing factor in sleep quality were oral hygiene neuroticism (β=.266), adjusted R2=.066. According to the results, neuroticism and conscientiousness are effective in decreasing the academic burnout. Also, neuroticism is effective in increasing the sleep quality.
조중현,김기홍,이정희,정운태,김흥업,정경원,강정훈,이종덕 대한소화기학회 1999 대한소화기학회지 Vol.34 No.1
Malignant fibrous histiocytoma (MFH) of the liver is very rare. We report a case of MFH of the liver with cystic change. A 56-year-old woman was admitted with abdominal pain on right upper quadrant and fever. Liver function tests showed nomal profiles and the concentrations of alpha fetoprotein (αFP), carcinoembrionic antigen (CEA) and CA 19-9 were 1.46 ng/mL, 4.53 ng/mL and 350 ng/mL, respectively. An abdominal computed tomography disclosed a 8.7×7.4 cm sized cystic mass with multiple internal septa in the left lobe of the liver. Histological examination of the resected tumor showed large pleomorphic cells, spindle cells with interspersed myxoid material, and occasional giant cells. Immunohistochemically, tumor cells were strongly positive for vimentin and alpha 1-antitrypsin, but negative for cytokeratin and epithelial membrane antigen. The myxoid material was positive for alcian blue-PAS stain.