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RISS 인기검색어
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- 저자 : 임채남(Chae Nam Lim) (검색결과 5 건)
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소화성 궤양 환자에서 Helicobacter pylori 의 약제 내성률과 재발현 및 재감염률을 고려한 H . pylori 박멸요법의 수립
송인성(In Sung Song),김나영(Na Young Kim),임채남(Chae Nam Lim),임선희(Sun Hee Lim),이계희(Kye Heui Lee),구명숙(Myung Sook Koo),정현채(Hyun Chae Jung),김정룡(Chung Yong Kim) 대한내과학회 1999 대한내과학회지 Vol.56 No.3
N/A Objective : This study was conducted to establish an ideal treatment regimen for H. pylori eradication in three aspects: clinical, microbiological, and reinfection. Methods : Four hundred thirty two patients with H. pylori positive peptic ulcer were randomized to receive two types of triple therapy: one includes colloidal bismuth subcitrate, metronidazole and tetracycline (BMT), and the other includes omeprazole, amoxicillin and clarithromycin (OAC). Results : More than 50% of symptom reduction within 1 week was 94.4% both in OAC and in BMT group. The percentages of side effects were 21.6% and 27.1% in OAC and BMT regimen, respectively. Good compliance with at least 85% intake was 99.0% and 95.2% in OAC and BMT regimen. The eradication rates of H. pylori were 85.9% and 89.1% in OAC and BMT regimen. Resistance rates to metronidazole and clarithromycin were 40.6% and 10.2% by E test, 74.3% and 27.0% by broth microdilution, and 45.3% and 10.9% by disk diffusion method. The eradication rates for H. pylori was 100% and 77.8% by BMT in patients with metronidazole-sensitive and -resistant strains, and 100% and 80.0% by OAC with clarithromycin- sensitive and -resistant strains, without significance by their resistances. The recrudescence rate within 1 year after eradication was 21.2% and 14.2% for OAC and BMT regimen without significant difference. The reinfection rate after 1 year was 4.0% and 5.0% for OAC and BMT regimen. Conclusion : Because the eradication rate of BMT regimen is 89.1% in spite of high metronidazole resistance rate, and there was no statistical difference in the aspects of symptom reduction, side effect, compliance, recrudescence and reinfection rate, BMT regimen is as favorable as OAC to eradicate H. pylori.
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이상희,김나영,이계희,임선희,원경헌,조윤숙,최욱렬,임채남 대한소화기학회 1999 대한소화기학회지 Vol.32 No.6
We experienced a case of a 41 year old woman who had ingested sodium bromate solution to attemp a suicide. After the ingestion, nausea, vomiting, and abdominal pain were developed, and acute pancreatitis, anuric acute renal failure, and hearing loss were followed. To cure this, hemodialysis diet restriction, and fluid therapy were performed. Two weeks later, acute renal failure began to be quickly restored. However, acute pancreatitis was serious until the 40th hospital day and was slowly improved. Bromate, which is used as a neutralizer in home permanent cold wave hair kits, has been reported causing serious poisoning such as renal failure, deafness, peripheral neuropathy, but it has not been reported as a pancreatitis inducing chemical, yet to our knowledge. We report the case o bromate-induced acute pancreatitis with review of the literatures.
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Helicobacter pylori 진단을 위한 PyloriTek 검사의 유용성
이상희,이계희,임선희,최신은,원경헌,임채남,최욱렬,김나영,구명숙 대한소화기학회 1999 대한소화기학회지 Vol.33 No.6
Background/Aims: CLO test is widely used as a rapid urease test. However, it needs 24 hours to diagnose negativity of Helicobacter pylori infection. Recently, PyloriTek test which is a new reagen strip rapid urease test is introduced. This new method needs only 60 minutes for diagnosing H. pylor infection. To evaluate the efficacy of the new test, we compared the sensitivity and specificity of PyloriTek test with those of CLO test, Gram stain, Giemsa stain and culture. Methods: Five differen test methods (PyloriTek test, CLO test, Gram stain, Giemsa stain and culture) were taken in 100 patients with gastric ulcer or duodenal ulcer to diagnose H. pylori infection. Results: The sensitivity and the specificity of each test were as follows: 95.6% and 87.8% in PyloriTek test; 91.8% and 95.1% in CLO test; 94.3% and 97.6% in Gram stain; 81.3% and 100% in Giemsa stain; 50.0% and 100% in culture. Among these five tests, the sensitivities of PyloriTek test, CLO test and Gram stain were similarly higher than those of Giemsa stain and culture. The specificity of PyloriTek tes (87.8%) was relatively lower than those of the other four tests. Conclusions: Although the specificity of PyloriTek test was relatively low, this test appears to be useful because of short testing time and high sensitivity.
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이상희,김나영,임선희,최신은,원경헌,임채남,최욱렬,이계희 대한소화기내시경학회 1999 Clinical Endoscopy Vol.19 No.6
Mucormycosis is an infection caused by fungi of the class Zygomycetes, order Mucorales. These are usual ubiquitous saprophytes but occasionally cause opportunistic infection in immunocompromised patients. Typically, these fungi invade blood vessels, and produce thrombosis and tissue infarction, so causing host fatality. These infections can be categorized into rhinocerebral, pulmonary, widely disseminated, gastrointestinal, cutaneous and miscellaneous form. Most of mucormycosis cases reported in Korea were rhinocerebral form except for three cases, which were gastrointestinal mucormycosis, accompanied with hematologic malignancy or immunosuppressing treatment. We experienced a 58-year-old male with gastric mucormycosis, who had diabetes and mild uremia without hematologic malignancy and immunosuppressive treatments. His chief complaints were abdominal pain and melena, and gastroscopy showed a 3 3 cm irregular edged ulcer considering malignancy. Its histological findings showed large, thin-walled, non-septate and right-angled branching fungal hyphae in necrotic tissue, diagnosed as mucormycosis. Finally he was dead due to severe hematemesis.
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