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임재웅,신화균,박영우,송인학,원용순,고은석 대한흉부외과학회 2006 Journal of Chest Surgery Vol.39 No.10
40세 여자가 앞가슴에 발생한 종양을 주소로 내원하였다. 종양은 흉벽에 생긴 결절성근막염으로 진단되었다. 결절성근막염은 섬유모세포의 증식을 특징으로 하는 드문 양성 연부조직 종양으로, 외과적 절제가 가장 효과적인 치료이다. 외과적 절제 후 저자들은 결절성근막염을 치험하였기에 문헌 고찰과 함께 이를 보고하는 바이다.
인조혈관 동정맥루 폐쇄의 치료에서 수술적 혈전제거술 및 재건술과 경피적 혈전제거술 및 혈관성형술의 비교연구
임재웅,원용순,김동현,신화균 대한흉부외과학회 2009 Journal of Chest Surgery Vol.42 No.4
Background: Salvaging prosthetic arteriovenous grafts can be performed using surgical or endovascular techniques. We conducted a retrospective analysis to compare the efficacy of these two methods for restoring dialysis graft function. Material and Method: We studied 41 patients who had received surgical thrombectomy with revision (Group A) or percutaneous thrombectomy with angioplasty (Group B) from January 2006 to December 2007. We compared them according to the patient characteristics and the location of stenotic lesions, and we analyzed the postintervention primary patency rates. Result: 21 patients underwent surgery and 20 patients underwent percutaneous balloon angioplasty. There were no significant differences of the patients’ characteristics between the two groups. Venous anastomotic stenosis was the most common cause of graft thrombosis in both groups. In Group A, 90.5% of the grafts remained functional at 6 months and 38.1% remained functional at 12 months. In Group B, 55.0% of the grafts were functional at 6 months and 20.0% of the grafts were functional at 12 months. The post-intervention primary patency rate was significantly better in Group A (p=0.034). Conclusion: Surgical treatment resulted in significantly longer post-intervention primary patency in this study, and this supports its use as the primary method of management for most patients in whom dialysis graft obstruction develops. 배경: 인조혈관 동정맥루 폐쇄의 구조요법으로는 수술적 방법과 중재적 혈관내 치료법을 사용할 수 있다. 인조혈관 동정맥루를 재개통 시키는데 이 두가지 방법의 효율성을 후향적으로 분석하였다. 대상 및 방법: 2006년 1월부터 2007년 12월까지 수술적 혈전제거술 및 재건술(그룹 A) 또는 경피적 혈전제거술 및 혈관성형술(그룹 B)을 시행받은 41명의 환자를 대상으로 환자의 임상적 특성, 협착부의 위치, 시술 후 일차 개통률을 비교하였다. 결과: 총 41명의 환자 중, 21명의 환자는 수술적 혈전제거술 및 재건술을 받았으며, 20명의 환자는 경피적 혈전제거술 및 혈관성형술을 받았다. 두 군간에 환자의 임상적 특성은 차이가 없었다. 두 군 모두에서 정맥 문합부 협착이 인조혈관 동정맥루 폐쇄의 가장 흔한 원인이었다. 시술 후 일차 개통률은 6개월 누적 개통률이 그룹 A 90.5%, 그룹 B 55%였으며, 1년 누적 개통률은 그룹 A 38.1%, 그룹 B 20.0%로 그룹 A가 통계적으로 의미 있게 높은 개통률을 보였다(p=0.034). 결론: 본 연구에서는 조기에 적절한 수술적 재건술을 시행함으로써 인조혈관 동정맥루의 구제가 가능하였고 비교적 우수한 개통률을 얻을 수 있었다. 인조혈관 동정맥루의 폐쇄가 발생하였을 경우 일차적인 치료방법으로서 수술적 재건술은 효과적인 방법이라고 생각된다.
어류 병원성 세균에 대한 월계수(Laurus nobilis) 잎 유래 sesquiterpene lactone과 수산용 항생제의 병용효과
임재웅,최지석,투르크 아이만,이미경,김도형,강소영 한국어병학회 2024 한국어병학회지 Vol.37 No.1
This study is a report on combinational effects between four sesquiterpene lactones (SLs) from bay laurel (Laurus nobilis) leaves, and oxytetracycline (OTC) or amoxicillin (AMX) against four fish pathogenic bacteria such as Vibrio anguillarum, V. harveyi, Edwardsiella tarda, and Streptococcus iniae. Individually, four SLs exerted little antibacterial activity against fish pathogenic bacteria. However, when combined with OTC or AMX, they showed synergistic interaction against pathogenic bacteria. Especailly, zaluzanin C (1) reduced the MIC of OTC (or AMX) eight-fold. Our results showed that combinations of SLs with antibiotics (ABTs) are more effective than ABTs alone to control pathogenic bacteria. The highest synergistic effect was observed when zaluzanin C (1) was combined with OTC or AMX against V. harvey or S. iniae, displaying significant reductions of MICs up to 8-fold (0.125 to 0.015 µg/mL and 0.0078 to 0.0009 µg/mL). In addition, zaluzanin C (1) improved the antibiotic potency of OTC against OTC resistant V. harveyi (250 µg/mL to 62.5 µg/mL). Synergism between ABTs and phytochemical such as SLs could be a therapeutically helpful concept to improve the efficacy of ABTs and prevent antibiotic resistance. These results suggest that SLs can be used as an alternative to reduce antibiotic resistance in aquaculture.
임재웅,이규봉 동아시아식생활학회 1999 동아시아식생활학회지 Vol.9 No.4
This study was conducted to investigate the antimicrobial activity of Prunus mume extracts. Prunus mume extracts have growth inhibitory activity to various microorganisms. Gram positive bacteria such as Bacillus cereus, Bacillus subtilis, Micrococcus leteus, Staphylococcus epidrimidis were more easily inhibited than Gram negative bacteria tested Vibrio parahaemolyticus, Salmonella typhimurium, Escherichia coli, Proteus vulgaris and Yeasts by Prunus mume extracts. Among several fractions of methanol extract, EtOAc & BuOH fractions were showed strong antibacterial activities, but those fractions were not showed on fungi.
임재웅,윤상문,정노희 한국응용과학기술학회 2010 한국응용과학기술학회지 Vol.27 No.1
Silicone surfactants are widely used in many industrial area because of its thermal stability and lower foaming property. But it has limitation to expand the application because of migration and bubble generation issues when it is mixed with organic surfactant. In this study, epoxy functionalized fluoro-silicone surfactant, perfluoro glycidoxypropyl polyether siloxane(PFGES), was synthesized using hydrosilylation reaction among perfluoro methyl hydrogen siloxane, allyl glycidyl ether, and allyl ployether in order to get lower surface tension, better thermal stability than conventional silicone surfactant, and reactivity with anhydride function.
GWP(Great work place)조직문화가 긍정심리자본과 조직몰입에 미치는 영향에 대한 연구 : 대전·충청지역 자동차 부품 제조업체를 중심으로
임재웅,장석인 공주대학교 KNU 기업경영연구소 2017 기업경영리뷰 Vol.8 No.2
This study is an empirical analysis on the effect of GWP(Great work place) organization culture on positive psychology capital, organizational commitment. Previous studies have focused on case studies for specific companies and comparative studies on GWP organizational culture have been carried out in recent years. However, there is a lack of research that specifically segmented the GWP organizational culture and observed specific fields. The purpose of this study is to analyze the GWP organizational culture of auto parts makers in DaeJeon and ChungCheong areas based on previous studies and to analyze the effects on positive psychological capital and emotional organizational commitment, As a result of this study, we have started a study to help executives in the related field introduce the GWP organizational culture. Pride and Camaraderie excluding trust in GWP organizational culture have a positive effect on organizational commitment, trust and Pride except camaraderie have a positive influence on self-efficacy of positive psychological capital, positive influence of positive psychological capital Confidence and camaraderie had a positive effect on resilience, but trust did not directly affect resilience. In addition, positive psychological capital has a positive effect on affective organizational commitment. This study analyzes the relationship between GWP organizational culture, positive psychological capital and organizational commitment, and presents the practical value to companies that intend to introduce GWP organizational culture. In addition, This study will help to expand the academic scope of GWP organizational culture research. 본 연구는 GWP(Great work place)조직문화가 구성원들에게 긍정심리자본(Positive Psychology Capital)과 정서적 조직몰입(Organizational Commitment)에 미치는 영향에 대한 실증 연구이다. 기존에 선행연구는 특정 기업에 대상으로 사례 연구를 진행하였으며 최근 업종별 GWP조직문화에 대한 비교 연구들이 진행되고 있다. 하지만, GWP조직문화를 전문적으로 깊이 있게 세분화 하여 특정 분야를 관측한 연구는 부족한 형편이다. 세부적인 변수 간에 상관관계에 대해 전문적으로 연구하기 위해 산업별, 업종별로 세분화된 연구가 필요하다고 보며, 본 연구는 기존 선행연구를 바탕으로 충청권 자동차 부품 제조업체의 구성원을 대상으로 GWP조직 문화를 분석하여 긍정심리자본 및 정서적 조직몰입에 대한 영향관계를 분석하고 검증하여 연구자가 실무자에게 학문적·실용적 가치를 줄 것으로 기대된다. 본 연구의 결과로 GWP조직문화가 정서적 몰입에 유의(+)한 영향을 미치며, 긍정심리자본의 자기효능감 및 복원력에 유의(+)한 영향을 주고, 긍정심리자본은 정서적 몰입에 유의(+)한 영향을 준다는 연구 결과를 얻었다. 본 연구는 GWP조직문화를 도입하려는 기업들에게 실무적인 차원에서 GWP조직문화와 긍정심리자본 및 조직몰입과의 관계를 분석하여 실용적 가치를 제시하고자 하며, 또한 연구자에게 GWP조직문화의 학술적 범위를 넓히고자 한다.
임재웅,김민재,이강한,정상혁,김대솔,김유연,김진원,이요한,김현수,박선영,김동현 전남대학교 의과학연구소 2024 전남의대학술지 Vol.60 No.3
Colonoscopy is a key procedure for the early detection of colorectal cancer. Despite its importance, the discomfort associated with colonoscopy often requires sedation, and the ideal sedation regimen remains to be determined. In this prospective randomized controlled trial, patients scheduled for colonoscopy were randomly assigned to two different sedation protocols. Group A received a combination of midazolam and propofol, while group B was given midazolam and pethidine. The study analyzed data from 51 patients, with 23 in group A and 28 in group B. The incidence of adverse events was similar across both groups. Additionally, no significant differences were observed in cecal intubation times or total procedure durations. Notably, group A had a lower frequency of required postural changes (1.0±0.7 vs. 1.5±0.7, p=0.02) and a reduced rate of manual compression (52.2% vs. 82.1%, p=0.02). There were no significant differences between the groups regarding subjective pain or overall satisfaction. Both sedation regimens were found to be safe and effective. The midazolam and propofol combination was associated with a smoother procedure, evidenced by fewer postural adjustments and less manual compression needed during colonoscopy.