F-12 The role of all-trans retinoic acid and ephrin receptor tyrosine kinase A2 signaling in bleomycin-induced pulmonary fibrosis

임아영,신미화,김송이,송주한,정경수,김은영,정지예,강영애,김영삼,김세규,장준,박무석 대한결핵 및 호흡기학회 2016 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.121 No.0

Idiopathic pulmonary fibrosis is a progressive and usually lethal disease of unknown pathophysiology. The aim of this study is to evaluate the role and related signal pathways of ATRA and EphA2 signaling in the bleomycin-induced pulmonary fibrosis in mice model. We studied four experimental mice groups (control group, bleomycin group, ATRA group, EphA2 mAb group). On day 21, the cell counts and protein concentration in the bronchoalveolar lavage fluid (BALF), changes in histopathology, hydroxyproline assay, and the expression of several signal pathway proteins and cytokine levels were compared among the groups. We report that bleomycin exposure significantly upregulated EphA2 and EphrinA1 expression. ATRA posttreatment attenuated lung injury score and reduced protein concentration of BALF. The expression of PI3K protein was significantly increased after bleomycin instillation, and decreased after ATRA posttreatment. In addition, ATRA led to a decrease of IL-6 and TNF-α production in the ATRA group compared to the control group. Inhibiting EphA2 receptor by intranasal EphA2 mAb instillation attenuated pulmonary fibrosis, reduced cell counts and protein concentration of BALF. Furthermore, bleomycin exposure upregulated the expression of Wnt5a and PI3K, and inhibiting EphA2 receptor downregulated both of them. The present data suggest that ATRA attenuates bleomycin-induced pulmonary fibrosis, and that it may regulate the PI3K dependent pathway. Furthermore, EphA2 antagonism attenuates the PI3K dependent pathway and Wnt/ß-catenin pathway, and decreased pulmonary fibrosis.

경계선 성격과 커플관계 만족도의 관계에서 다름 수용 태도와 갈등해결전략의 역할

임아영,이슬아 한국건강심리학회 2023 한국심리학회지 건강 Vol.28 No.5

본 연구에서는 경계선 성격특성이 커플관계 만족도에 미치는 영향에서 다름 수용 태도와 갈등해결전략의 매개 역할을 검증하였다. 성인 300명을 대상으로 커플관계 다름 수용 척도를 비롯한 자기보고식 척도들을 실시하고 분석을 진행하였다. 그 결과, 경계선 성격은 커플관계 만족도에 직접 유의한 영향을 미치지 않았으나, 다름 수용 태도를 매개로 커플관계 만족도에 유의한 부적 영향을 미쳤다. 또한, 경계선 성격이 커플관계 만족도에 영향 미치는 과정에서 다름 수용 태도와 긍정적 갈등해결전략의 순차 매개효과도 유의하였다. 성별 및 결혼상태에 따른 차이도 유의하였는데, 경계선 성격과 커플관계 만족도의 관계에서 다름 수용 태도의 매개효과는 남성에게서, 다름 수용 태도와 긍정적 갈등해결전략의 순차 매개효과는 기혼자에게서만 유의하였다. 이러한 결과를 바탕으로 시사점과 제한점을 논의하였다. This study examined the mediating role of accepting differences and conflict resolution strategies on the influence of borderline personality traits on couples’ relationship satisfaction. The data of 300 adults who completed the Acceptance for Differences in Couple Relationships Scale (ADCRS) and other self-reporting scales were analyzed. The results indicated that while borderline personality did not directly impact relationship satisfaction, it significantly impacted relationship satisfaction through the mediating role of accepting differences. Furthermore, the study found significant sequential mediating effects of accepting differences and positive conflict resolution strategies in the relationship between borderline personality and relationship satisfaction. Notably, gender and marital status differences were observed. Specifically, accepting differences mediated the relationship between borderline personality and relationship satisfaction for men, but not for women. Additionally, the sequential mediating effect of accepting differences and positive conflict resolution strategies was only significant for married individuals, but not for unmarried individuals. The implications and limitations of these findings are discussed.

APCC SCoPS 계절 예측 모형의 Real-time 예측 성능 분석

임아영,양유빈,민영미,함수련 한국기상학회 2019 한국기상학회 학술대회 논문집 Vol.2019 No.4

코로나19 발생 이후 소비자의 온라인 식품 구매 채널 선택과 구매 만족도

임아영,최명훈,유소이 한국지역사회생활과학회 2023 한국지역사회생활과학회지 Vol.34 No.3

This study examined the factors influencing online food purchasing (channel selection, purchasing share, and satisfaction with online food purchases) after the occurrence of coronavirus disease 2019 (COVID-19), using raw data from the 2021 Food Consumption Behavior Survey collected by the Korea Rural Economic Institute. The results of this study revealed that when it comes to selecting online stores (channels) for food purchases, consumers prioritized accuracy and promptness of delivery, stability of payment systems, and price. The reasons for choosing online food purchases were primarily for the convenience and efficiency offered, such as delivery services and their timesaving aspects. Additionally, consumers also considered superior product quality and variety as the advantages of online food shopping. Furthermore, in terms of online food purchasing behavior, the following were observed: First, consumers primarily use mobile devices for online food shopping. Specialized online shopping malls are the most frequently used distribution channels for primary food purchases online. Additionally, when analyzing the factors influencing the choice of the online food purchasing channel (Personal Computer [PC] vs Mobile Phone), BMI (Body Mass Index) was found to be a significant factor influencing the choice. Second, the proportion of online food purchases was reported to be higher or constant compared to the previous year, and the factors influencing this trend were concerns about the influx of food from external sources and motivations, gender, income, household size, seniors. Third, when analyzing the factors influencing overall satisfaction with online food purchases, it was found that the proportion of online food purchases, satisfaction with price and quality, concerns about external food, motivations, and generations were significant factors.

후쿠시마 원전사고로 인한 방사능 유출과 수산물 안전 문제

임아영 이화여자대학교 스크랜튼대학 스크랜튼학부 2015 ATE Vol.5 No.-

Incident-angle-based Selective Tunability of Resonance Frequency in Terahertz Planar Metamolecules

임아영,이중욱 한국광학회 2022 Current Optics and Photonics Vol.6 No.6

We carry out numerical simulations of the responses of planar metamaterials composed of metamolecules under obliquely incident terahertz waves. A Fano-like-resonant planar metamaterial, with two types of resonance modes originating from the two meta-atoms constituting the meta-molecules, exhibits high performance in terms of resonance strength, as well as the outstanding ability to manipulate the resonance frequency by varying the incident angle of the terahertz waves. In the structure, the fundamental electric dipole resonance associated with Y-shaped meta-atoms is highly tunable, whereas the inductive-capacitive resonance of C-shaped meta-atoms is relatively omnidirectional. This is attributed to the electric near-field coupling between the two types of meta-atoms. Our work provides novel opportunities for realizing terahertz devices with versatile functions, and for improving the versatility of terahertz sensing and imaging systems.

자기결정적 고독과 성격 및 심리적 건강의 관계

임아영,이준득,이훈진 한국임상심리학회 2012 Korean Journal of Clinical Psychology Vol.31 No.4

Solitude, defined as the absence of social interaction, has both positive and negative sides. However, most previous studies have focused on its negative sides such as loneliness and social anxiety. The aim of the current study was to focus on the positive side of solitude and to examine the role of self-determination factor, which is hypothesized to lead positive experiences during solitude. In study 1, the Self-determined Motivation Scale for Solitude and Relationship(SMS) was adapted and validated. And the relationships among SMS, psychological health, and virtues such as creativity, openness, and self-control were then investigated using data from 347 undergraduate students. With proper reliability, SMS was found to be composed of four factors: Self-Determined Solitude(SDS), Not Self-Determined Solitude(NSDS), Self-Determined Relationship(SDR) and Not Self-Determined Relationship (NSDR). SDS showed a positive relationship with the preference of solitude, and productivity in solitude. In addition, SDS showed a positive correlation with positive characteristics, including life satisfaction, creativity, openness, and self-control. However, NSDS showed a positive relationship with psychological distress including loneliness, depression, and social avoidance. In study 2, the relationships among SMS, temperament and personality, and attachment were investigated, based on data from 189 undergraduate students. According to the results, both SDS and NSDS were linked to high introversion, and low reward dependence (social sensitivity), however, only NSDS was related to high harm avoidance, low self-directedness, and low cooperativeness. In addition, NSDS showd an association with avoidant and anxious attachment styles. The findings of the current study suggest the positive aspects of self-determined solitude. Results of this study also demonstrated the differences between self-determined solitude motivation and not self-determined solitude motivation in temperament, personality, and attachment. Finally, the implications and limitations of this study, as well as suggestions for future studies were discussed.

코로나 시기 온라인 교양교육에 대한 학습자 인식 및 만족도 연구-K 대학의 사례를 중심으로

임아영,이대연,이희숙 한국교양교육학회 2023 교양교육연구 Vol.17 No.5

본 연구는 코로나19 팬데믹이 본격화된 2020년과 2021년에 K 대학교의 온라인 교양교육에 대한학습자의 인식과 만족도를 조사하고, 변화 양상을 분석하였다. 연구 결과를 요약하면 다음과 같다. 첫째, 2020년에 비해 2021년 온라인 교양수업의 만족도가 전반적으로 상승하고 인식이 개선되었으나, 교수자의 충실한 피드백과 흥미로운 수업 구성에 대한 만족도는 여전히 낮게 나타났다. 둘째, 향후온라인 교양수업에 대한 수강 의향은 증가했지만, 교양실습 과목의 경우 수강 의향이 낮게 나타났으며, 인문계 및 이공계에 비해 예체능계 온라인 교양수업의 만족도가 낮았다. 셋째, 학습자들의 온라인수업 환경이 개선된 것으로 나타났으나, 디지털 정보격차 문제와 장애학생 지원 시스템에 대한 고려가 필요하다. 넷째, 학습자는 녹화된 강의 형태를 가장 선호하며, 향후 실시간 화상 강의에서 녹화 기능과 추가 영상 제공 등을 통한 보완이 필요하다. 다섯째, 2020년과 동일하게 2021년에도 과제 부담과 실습수업의 어려움, 교수와의 소통 문제 등이 온라인 교양수업의 단점으로 나타났으며, 이를 극복하기 위해 오프라인 실습 활동 병행 및 플립러닝 등의 방법을 고려할 필요가 있다. 여섯째, 2020년에 이어 2021년도에도 학습자들은 교수의 강의 전달력과 온라인 수업에 대한 교수의 관심 및 적극성이 온라인 교양수업질 향상을 위해 가장 중요한 덕목으로 인식하는 것으로 나타났다. 이러한 연구 결과를 바탕으로 온라인교양교육이 나아가야 할 방향과 개선 방안에 대한 시사점 및 추후 연구를 제안하였다. This study investigated the perceptions and satisfaction level of learners regarding online general education at K University during the COVID-19 pandemic in 2020 and 2021. The research aimed to analyze the changes in learners' perceptions and level of satisfaction. The summarized findings of the study are as follows: First, compared to 2020, the level of overall satisfaction among students with online general education classes increased in 2021, and learners' perceptions improved. However, their satisfaction with instructors' feedback and interesting class structures remained low. Second, there was an increased intention on the part of students to enroll in online general education courses, but the intention was lower for liberal arts practicum courses. Student satisfaction with online general courses in the performing arts field was lower compared to humanities and STEM (Science, Technology, Enginerring, Mathematics) fields. Third, learners reported an improvement in their online learning environments. However, addressing the digital information gap and supporting students with disabilities require consideration. Fourth, learners preferred pre-recorded lectures, and meeting their demands through features like recording functions and additional videos in real-time video lectures was necessary. Fifth, similar to 2020, learners identified assignment burdens, difficulties in practical courses, and communication issues with instructors as disadvantages of online liberal arts education. Sixth, in both 2020 and 2021, learners recognized that instructors' delivery skills and their interest and enthusiasm in online classes were the most crucial factors in enhancing the quality of online liberal arts education. Based on these findings, implications for the future direction and improvement of online liberal arts education were proposed, along with suggestions for further research.

[샘터가족실] 외삼촌의 여행

임아영 샘터사 1999 월간 샘터 Vol.30 No.5

수도권 집중호우 사례에 대한 WRF 미세물리 방안 민감도 실험

임아영,노준우,최영진 한국기상학회 2015 한국기상학회 학술대회 논문집 Vol.2015 No.4