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신면우(MW Shin),이효표(HP Lee),고영우(YW Koh),이진용(JY Lee) 대한산부인과학회 1970 Obstetrics & Gynecology Science Vol.13 No.10
A case of transverse septum of vagina, obscuringthe cervix, with a cental opening of a few millimeters in diameter is presented with a brief review of the concerned literature.
이효표(HP Lee),신면우(MW Shin) 대한산부인과학회 1982 Obstetrics & Gynecology Science Vol.25 No.10
Five fetal biophysical variables, fetal breathing movements, fetal movements, fetal tone, qualitative amniotic fluid volume, and the nonstress test were measured in the same observation period in 61 high risk and 30 normal patients hospitalized at S.N.U.H. All delivered within one week of the last observation. The relationship between individual biophysical variables and combinations of variables to the outcome of pregnancy as judged by five-minute Apgar Score, fetal distress in labor, and perinatal mortality rate was determined. For single test, the false negative rate was significantly low except qualitative amniotic fluid volume and was similar volume. Combining tests resulted in a significant change in both the false negative and false positive rates as compared to any single test. The most accurate differentiation of the normal from the compromised fetus was obtained when all five variables were studied. The perinatal mortality ranged from 0 when all variables were normal to 500 per 1,000 when 3 variables were abnormal. These data suggest that combined fetal biophysical testing is a more accurate method of antepartum fetal evaluation than any single method relatively.
신면우(MW Shin),이효표(HP Lee),신경자(KJ Shin),나태경(TK Rha) 대한산부인과학회 1970 Obstetrics & Gynecology Science Vol.13 No.10
The occurrence of true knot of the umbilical cord is rare and occasionally they may be pulled so tight as to become compressed and lead to fetal distress and death. A case of true knot of umbilical cord resulting in fetal death in utero is presented with the brief review of the literatures.
자궁경부암 및 난소암 환자에 있어서 수술후 OK-432투여가 면역반응에 미치는 영향에 관한 연구
이효표(HP Lee),조경훈(KH Cho),김석현(SH Kim),이필량(PY Lee),강순범(SB Kang),신면우(MW Shin) 대한산부인과학회 1989 Obstetrics & Gynecology Science Vol.32 No.1
1988년 3월부터 1988년 6월까지 서울대학교병원 산부인과에 자궁경부암 및 난소암으로 입원 하여 수술 시행받은 환자 43명에서 OK-432 투여군 26명과 대조군 17명의 면역반응을 비교 분석하여 다음과 같은 결론은 얻었다. 1. OK-432 투여군의 평균연령은 49.5세이엇고, 총 26명중 자궁경부암의 23명, 난소암의 3명 이었다. 2. 대조군의 평균연령은 47.8세이며, 총 17명중 자궁경부암이 13명, 난소암이 4명이었다. 3. 말초혈액임파구수는 OK-432 투여군에서 투여전 1420+-440/mm^3에서 투여후 2220+-740/mm^3으로 유의하게 증가하였다. 대조군은 각각1530+-560/mm^3과 1610+-630/mm^3으로 유의한 차이가 없었다. 4. 자연살해세포능은 OK-432 투여군에서 투여전에 41.2+-11.3%에서 투여후에 57.2+-16.5%로 유의하게 증가하였으며 대조군은 각각 40.5+-13.6% 45.2+-15.7%로 유의한 차이가 없었다. 5 OK-432 투여시 미열과 주사부위의 동통외에 특별한 부작용은 나타나지 않았다. OK-432 a streptococcal preparation, is a bacterial immunostimulant whose antitumor effect has been demonstrated both experimentally and clinically. To ivestigate OK-432 immunotherapy on immunological response, we compared natural killer cell activity nad number of peripheral blood lymphocytes in patients with uterine cervical and ovarian carcinoma after surgical operations (n=27) to those in control patients (n=17) The results were as follows. 1. The mean age of OK-432 treated group was 49.5 year. 23 were cervical carcinoma and 3were ovarian carcinoma 2. The mean age of control patients was 47.8years. 13 were cervical carcinoma and 4 were ovarian carcinoma 3. In OK-432 treated group , number of peripheral blood lymphocyte before treatment was 1420+-440/mm^3 and it increased significantly to 2220+-740/mm^3 after treatment . In control group , it was 1530+-560/mm^3 and 1610+-630/mm^3 each. 4. In OK-432 treated group , natural killer cell activity before treatment was 41.2+-11.3% and it significantly increased to 57.2+-16.5% after treatment . In control group , it was 40.5+-13.6% and 45.2+-15.7% each. 5. No significantly side effects of OK-432 was noticed except for transient mild fever and pain at the site of injection.
최영민,강순범,이효표,신면우,장윤석,박찬일,박진완,서대식,하성환 대한산부인과학회 1993 Obstetrics & Gynecology Science Vol.36 No.6
서울대학병원 산부인과학교실에서는 1959년부터 1987년까지 서울대학병원 산부인과와 치료 방서선과에서 자궁경부암으로 진단 및 치료받은 2555에의 임상양상과 1977년 1월부터 1982 년 12월까지 치료를 받은 침윤성 자궁경부암환자들의 임상기별 5년생존율을 생명표법(life table analysis)으로 구하여 다음과 같은 결과를 얻었다. 1. 자궁경부암의 임상양상(1959년~1987년) 1) 연평균 환자수는 88.1명이었다. 2) 연령별 분포는 41~50세군이 전체 환자의 41.9%를 차지하여 가장 높은 발생빈도를 보였다. 3) 임상병기별 분포는 II기가 41.4%로 가장 높은 빈도를 보였으며, I기(38.0%), 0기와 III기 (8.8%), IV기(3.0%)순이었다. 4) 조직병리학적 분포는 편평상피세포암이 95%, 선암이 4.3%, 선편평상피세포암이 0.7%였다. 5) 임파선전이는 I기에서는 15.2%, II기에서는 33.8%였다. 2. 생명표법(life table analysis)에 의한 침윤성 자궁경부암 환자의 5년생존율(1977년~1982년) 1) 대상환자는Ia기 37예, Ib기 199예, IIa기 127예, IIb기 171예, III기 64예, IV기 29예였다. 2) 5년생존율은 Ia기 100%, Ib기 80.8%, IIa기 74.5%, IIb기 66.8%, III기 51.9%, IV기 27.4%였다. From January 1959 to December 1987, 2555 cases of uterine cervical cancer were evaluated at Seoul National University Hospital, Seoul, Korea. The purpose of this study was to analyze the clinical profile and 5-year survival rate of cervical cancer. The mean number of patients per year was 88.1 cases. The majority of patients, 1070 cases (41.9%), was found in the group of age between 41 and 50. The distributions of patients by the clinical stages were as follows: Stage 0, 224 cases(8.8%); Stage I, 971 cases (38.0%); Stage II, 1059 cases (41.4%); Stage III, 225 cases (8.8%); and Stage IV, 76 cases (3.0%). The result of histopathologic subtype were distributed as follows: squamous cell carcinoma was 95.0%, adenocarcinoma was 4.3% and adenosquamous cell carcinoma was 0.7%. The frequency of lymph node metastasis was 15.2% in Stage I and 33.8% in Stage II. We have also evaluated the 5-year survival rate of the patients treated from January 1977 to December 1982, according to life table analysis. The results were as follows: Stage Ia, 100%: Stage Ib, 80.8% ; Stage IIa, 74.5%; Stage IIb, 66.8%; Stage III, 51.9%; Stage IV, 27.8%.